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| 1 | Synthesis, bioactivity, action mode and 3D-QSAR of novel anthranilic diamide derivatives显示文摘To study the pesticide effect, action mode, structure-activity relationships (SARs) of anthranilic diamide insecticide and screen highly active pesticides, novel anthranilic diamide derivatives were synthesized.Bioassays indicated that all of the title compounds displayed 100% mortality against diamondback moth and oriental armyworm at 100 mg/L, among which 12 v and 12 w showed 100% insecticidal acitvity at 5 mg/L. Surprisingly compound 12 w exhibited better insecticidal acitvity than commercialized chlorantraniliprole against Pyrausta nubilalis (0.1 mg/L) and Cnaphalocrocis Medinalis (2 mg/L). 3 D-QSAR and SARs statistical analysis revealed that title compounds with R^2 fixed as methoxy had the highest probability possessing high activity. The calcium fluorescence measurements on neurons revealed that E series compounds containing pyrazinyl may have a molecular target different from caffeine on ryanodine receptors rather than the voltage-gated calcium channel present on cytomembran. | Weijie Liu Jiao Li Kai He Fangfang Huang Yi Ma Yuxin Li Qingshan Li Fengbo Xu | 2019 | Chinese Chemical Letters2019，30，2： | 4 |
| 2 | Magnetic ED- TA-modified chitosan/SiO2/Fe3 04 adsorbent: Preparation, char- acterization, and application in heavy metal adsorption 显示文摘 | Ren Yong Abbood Hayder A He Fengbo | 2013 | Chem Eng J2013，226，： | 1 |
| 3 | Ultrasound-driven BaTiO_(3) nanorobots patching immunologic barrier to cure chronic rheumatoid arthritis显示文摘The disruption and reconstruction of the TREM2^(+) tissue resident macrophage(TRM)barrier on the surface of synovial lining play a key role in the activation and'remission'of rheumatoid arthritis(RA),which engender the prediction of this immunologic barrier as a potential driver for the achievement of'cure'in RA.However,strategies to promote the reconstruction of this barrier have not been reported,and the effect of patching this barrier remains unidentified.On the other hand,appropriate piezoelectric stimulation can reprogram macrophages,which has never been exerted on this barrier TRM yet.Herein,we design piezoelectric tetragonal BaTiO_(3)(BTO)ultrasound-driven nanorobots(USNRs)by the solvothermal synthesis method,which demonstrates satisfactory electro-mechanical conversion effects,paving the way to generate controllable electrical stimulation under ultrasound to reprogram the barrier TRM by minimally invasive injection into joint cavity.It is demonstrated that the immunologic barrier could be patched by this USNR effectively,thereby eliminating the hyperplasia of vessels and nerves(HVN)and synovitis.Additionally,TREM2 deficiency serum-transfected arthritis(STA)mice models are applied and proved the indispensable role of TREM2 in RA curing mediated by USNR.In all,our work is an interesting and important exploration to expand the classical tetragonal BTO nanoparticles in the treatment of autoimmune diseases,providing a new idea and direction for the biomedical application of piezoelectric ceramics. | Le Jiang Yifan Wang Chunlin Liu Nan Xu Wenshuo Li Lei Wang Yixian Wu Jingyun Wang Zhijun He Fengbo Sun Lingyun Zhao Qiong Wu Xiumei Wang Huihui Yuan Xiaohui Wang Xiaodan Sun | 2023 | Journal of Advanced Ceramics2023，12，5： | 0 |
| 4 | 多块巨大柿子粪石引起的胃出口梗阻病例显示文摘A phytobezoar is a bezoar or trapped mass in the gastrointestinal system that consists of indigestible plant material such as fibers,skins and seeds.A persimmon phytobezoar(considered to be harder than other types of phytobezoars)is formed after frequent consumption of persimmons.The complication of gastrointestinal tract obstruction from bezoars was found to exist in the intestines but was rarely reported in the gastric tract because of its flexible volume.Here we present a 57-yearold man with persimmon phytobezoars,which ultimately led to gastric outlet obstruction. | Fengbo Tan Hongbin Mo Xiao He Haiping Pei | 2019 | Gastroenterology Report2019，7，1： | 0 |
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