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| 1 | Potential predictive factors for pathologic complete response after the neoadjuvant treatment of rectal adenocarcinoma:a single center experience显示文摘Objective:To assess the response rate of patients with rectal adenocarcinoma to neoadjuvant therapy and to identify the predictors of histological regression after neoadjuvant radiotherapy(RT)or concurrent chemoradiotherapy(CCRT).Methods:This study recruited 64 patients.The patients had resectable cancer of the lower and the middle rectum(T3/T4 and/or N+)without distant metastasis and received neoadjuvant RT or CCRT followed by radical surgery with total mesorectal excision(TME)between January 2006 and December 2011.The patients were classified into non-response(NR),partial response(PR),and pathologic complete response(p CR)based on the Dworak tumor regression grading system.Results:The median age of patients was 57 years(ranging from 22 to 85).A total of 24 patients were treated with neoadjuvant CCRT,whereas 40 patients were treated with RT alone.Abdominoperineal resection(APR)was performed on 29 patients(45%).Anterior resection with TME was performed on 34 patients(53%).One patient had local resection.Histologically,12(19%),24(73%),and 28(44%)patients exhibited p CR,PR,and NR,respectively.Univariate analysis revealed that the predictors of tumor regression were as follows:the absence of lymph node involvement from initial imaging(c N0)(P=0.021);normal initial carcinoembryonic antigen(CEA)level(P=0.01);hemoglobin level≥12 g/dl(P=0.009);CCRT(P=0.021);and tumor downstaging in imaging(P=0.001).Multivariate analysis showed that the main predictors of p CR were CT combined with neoadjuvant RT,c N0stage,and tumor regression on imaging.Conclusions:Identifying the predictors of p CR following neoadjuvant therapy aids the selection of responsive patients for nonaggressive surgical treatment and possible surveillance. | Feryel Letaief Meher Nasri Mouna Ayadi Khedija Meddeb Amina Mokrani Yosra Yahyaoui Nesrine Chraiet Henda Raies Amel Mezlini | 2017 | Cancer Biology & Medicine2017,14,3: | 3 |
| 2 | Effects of cryopreservation on human sperm deoxyribonucleic acid integrity显示文摘 | Nassira Zribi Nozha Feki Chakroun Henda El Euch Jalel Gargouri Ali Bahloul Leila Ammar Keskes | 2010 | Fertility and Sterility2010,,1: | 1 |
| 3 | Exploration techniques of the spatial data warehouses : Overview and application to incendiary domain显示文摘 | Haier Baazaoui Zghal Samifciiz Henda Ben Ghezala | 2001 | IEEE Conference on Computer System2001,7,3: | 1 |
| 4 | Perfluoroalkyl epoxides :Synthesis and conversion into ionic surfactants显示文摘 | Ayari Abdelhamid Mekni Henda Grayaa Jaoued Najeh | 2012 | Mediterranean Journal of Chemistry2012,,: | 1 |
| 5 | Comparison of two chickpea varieties regarding their re- sponses to direct and induced Fe dificiency 显示文摘 | Henda Mahmoudi Hans-Wemer Koyro Ahmed Debez et a/ | 2009 | Environmental and experimental botany2009,66,3: | 1 |
| 6 | Beneficial insect attraction to light traps with different wavelengths显示文摘 | HENDA N WAYNE C B SEMI N | 1999 | Biological Control1999,16,: | 1 |
| 7 | Beneficial Insect Attraction to I,ight Traps with Different Wavelengths显示文摘 | Henda N Wayne C Bailey | 1999 | Biological Control1999,16,: | 1 |
| 8 | Biochemical basis of high temperature inhibition of ethylene biosynthesis in ripening tomato fruits 显示文摘 | Biggs M S Woodson W R Henda A K | 1988 | Physiologia Plantarum1988,,72: | 1 |
| 9 | Expression of HBsAg and preS2-S protein in different yeast based system: A comparative analysis显示文摘 | Nadia Hadiji-Abbes Istabrak Borchani-Chabchoub Henda Triki Radhouane Ellouz Ali Gargouri Raja Mokdad-Gargouri | 2009 | Protein Expression and Purification2009,,2: | 1 |
| 10 | QoS Assurance for Service-Based Applications Using Discrete-Event Simulation显示文摘 | Jamoussi Yassine Driss Maha Jézéquel Jean-Marc Ghézala Henda Hajjami Ben | 2010 | International Journal of Computer Science Issues (IJCSI)2010,,: | 1 |
| 11 | A Guidance Process for the Selec- tion of Business Process Modeling Techniques for tile Revised Business Process Reengineering 显示文摘 | Leila Jamel Menzli Sonia Ayachi Ghannouchi Henda Hadjami Ben Ghezala | 2007 | Journal of Convergence Information Technology2007,2,2: | 1 |
| 12 | Optical and structural properties of SiOx and SiNx materials 显示文摘 | Dehan E Temple-Boyer P Henda R | 1995 | Thin Solid Films1995,266,1: | 1 |
| 13 | Combined analysis of interferon-γ and interleukin-10 gene polymorphisms and chronic hepatitis C severity显示文摘 | Nadia Bouzgarrou Elham Hassen Karim Farhat Olfa Bahri Sallouha Gabbouj Nadia Maamouri Nabil Ben Mami Hammouda Saffar Abdelhalim Trabelsi Henda Triki Lotfi Chouchane | 2009 | Human Immunology2009,,4: | 1 |
| 14 | Testicular Synovial Sarcoma:A Case Report显示文摘This paper reports a case of testicular synovial sarcoma with molecular genetic analysis.A 24-year-old male presented with painless scrotal mass.Ultrasonography showed a heterogeneous mass of 66 mm×34 mm in size involving the inguinal region.Histological examination of a surgical biopsy showed a gradeⅢmonophasic growth pattern of spindle cell proliferation.Immunohistochemical analyses indicated positive staining for pancytokeratine and epithelial membrane antigen.Cytogenetic analysis showed the presence of CYT-SSX1 mutation,and CT scan showed non-specific pleural micro-nodules with a size of 7.5 mm.The patient had an extended left orchidectomy but was lost to follow-up for 1 year.A local recurrent scrotal mass of 32 mm×25 mm,multiple inguinal lymph nodes,and increased pleural nodules,which were confirmed by histological examination,were treated with three cycles of adriamycine and ifosfamide chemotherapy,surgical resection,and radiotherapy with complete response.After 3 months,the patient developed local recurrence and pulmonary metastases that did not respond to second-line chemotherapy based on gemcitabine and paclitaxel.The patient had dyspnea at the time of this writing and chest pain,and is under third-line chemotherapy based on Deticene after 30 months of following up.This patient died on November 16,2012 after a resperatory failure and malignant plural effusion. Synovial sarcoma should be considered in the differential diagnosis of soft tissue tumor and it should be aggressively treated to improve prognosis.Although our patient has shown numerous factors of bad prognosis,he has had a relatively long survival time. | Mejri Nesrine Rym Sellami Raoudha Doghri Hela Rifi Henda Raies Amel Mezlini | 2012 | Clinical oncology and cancer resexreh2012,9,4: | 0 |
| 15 | Oxidative stress in male infertility and therapeutic approach: A mini-review显示文摘Growing evidence suggests that oxidative stress is a major cause of male infertility.Spermatozoa are highly sensitive cells due to the vulnerability of their membrane fatty acids and the diminished antioxidant defense.Reactive oxygen species(ROS)impact multiple signaling pathways involved in mitochondrial dysfunction,hormonal unbalance and semen quality decline.The origin of ROS is diverse,including generated normal cellular metabolism,environmental exposure,advanced paternal age and inflammation.Research has indicated that antioxidant supplementation can improve oxidative stress and reduce the risk of chronic diseases.Moreover,it is widely known that antioxidant supplementation can enhance sperm quality and increase the pregnancy rate in couples undergoing fertility treatments.The current study highlights the deleterious effect of ROS and its impact on semen function.In addition,it contributes to the development of a clinical approach for the use of antioxidants in the management of male infertility. | Marwa Lahimer Henda Mustapha Véronique Bach Hafida Khorsi-Cauet Moncef Benkhalifa Mounir Ajina Habib Ben Ali | 2023 | Asian pacific Journal of Reproduction2023,12,6: | 0 |
| 16 | Free Convection of a Viscous Electrically Conducting Fluid Past a Stretching Surface显示文摘Free convection of a viscous electrically conducting liquid past a vertical stretching surface is investigated in the presence of a transverse magnetic field.Natural convection is driven by both thermal and solutal buoyancy.The original partial differential equations governing the problem are turned into a set of ordinary differential equations through a similar variables transformation.This alternate set of equations is solved through a Differential Transform Method(DTM)and the Pade approximation.The response of the considered physical system to the non-dimensional parameters accounting for the relative importance of different effects is assessed considering different situations. | Abdulmajeed D.Aldabesh P.K.Pattnaik S.Jena S.R.Mishra Mouna Ben Henda Iskander Tlili | 2022 | Fluid Dynamics & Materials Processing2022,18,2: | 0 |
| 17 | Exogenous approach to improve topic segmentation显示文摘Purpose-Topic segmentation is one of the active research fields in natural language processing.Also,many topic segmenters have been proposed.However,the current challenge of researchers is the improvement of these segmenters by using external resources.Therefore,the purpose of this paper is to integrate study and evaluate a new external semantic resource in topic segmentation.Design/methodology/approach-New topic segmenters(TSS-Onto and TSB-Onto)are proposed based on the two well-known segmenters C99 and TextTiling.The proposed segmenters integrate semantic knowledge to the segmentation process by using a domain ontology as an external resource.Subsequently,an evaluation is made to study the effect of this resource on the quality of topic segmentation along with a comparative study with related works.Findings-Based on this study,the authors showed that adding semantic knowledge,which is extracted from a domain ontology,improves the quality of topic segmentation.Moreover,TSS-Ont outperforms TSB-Ont in terms of quality of topic segmentation.Research limitations/implications-The main limitation of this study is the used test corpus for the evaluation which is not a benchmark.However,we used a collection of scientific papers from well-known digital libraries(ArXiv and ACM).Practical implications-The proposed topic segmenters can be useful in different NLP applications such as information retrieval and text summarizing.Originality/value-The primary original contribution of this paper is the improvement of topic segmentation based on semantic knowledge.This knowledge is extracted from an ontological external resource. | Marwa Naili Anja Habacha Chaibi Henda Hajjami Ben Ghezala | 2016 | International Journal of Intelligent Computing and Cybernetics2016,9,2: | 0 |