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| 1 | Outcomes of submucosal(T1b) esophageal adenocarcinomas removed by endoscopic mucosal resection显示文摘AIM To investigate the outcomes and recurrences of p T1 b esophageal adenocarcinoma(EAC) following endoscopic mucosal resection(EMR) and associated treatments.METHODS Patients undergoing EMR with pathologically confirmed T1 b EAC at two academic referral centers were retrospectively identified.Patients were divided into 4 groups based on treatment following EMR:Endoscopic therapy alone(group A),endoscopic therapy with either chemotherapy,radiation or both(group B),surgicalresection(group C) or no further treatment/lost to follow-up(<12 mo)(group D).Pathology specimens were reviewed by a central pathologist.Follow-up data was obtained from the academic centers,primary care physicians and/or referring physicians.Univariate analysis was performed to identify factors predicting recurrence of EAC.RESULTS Fifty-three patients with T1 b EAC underwent EMR,of which 32(60%) had adequate follow-up ≥ 12 mo(median 34 mo,range 12-103).There were 16 patients in group A,9 in group B,7 in group C and 21 in group D.Median follow-up in groups A to C was 34 mo(range 12-103).Recurrent EAC developed overall in 9 patients(28%) including 6(38%) in group A(median:21 mo,range:6-73),1(11%) in group B(median:30 mo,range:30-30) and 2(29%) in group C(median 21 mo,range:7-35.Six of 9 recurrences were local;of the 6 recurrences,5 were treated with endoscopy alone.No predictors of recurrence of EAC were identified.CONCLUSION Endoscopic therapy of T1 b EAC may be a reasonable strategy for a subset of patients including those either refusing or medically unfit for esophagectomy. | Darren D Ballard Neel Choksi Jingmei Lin Eun-Young Choi B Joseph Elmunzer Henry Appelman Douglas K Rex Hala Fatima William Kessler John M DeWitt | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，20： | 2 |
| 2 | Association Between Helicobacter pylori and Barrett’s Esophagus, Erosive Esophagitis, and Gastroesophageal Reflux Symptoms显示文摘 | Joel H. Rubenstein John M. Inadomi James Scheiman Philip Schoenfeld Henry Appelman Min Zhang Val Metko John Y. Kao | 2014 | Clinical Gastroenterology and Hepatology2014，，2： | 2 |
| 3 | In Vivo Molecular Imaging of Barrett’s Esophagus With Confocal Laser Endomicroscopy显示文摘 | Matthew B. Sturm Cyrus Piraka B. Joseph Elmunzer Richard S. Kwon Bishnu P. Joshi Henry D. Appelman D. Kim Turgeon Thomas D. Wang | 2013 | Gastroenterology2013，，1： | 1 |
| 4 | Association Between Helicobacter pylori and Barrett’s Esophagus, Erosive Esophagitis, and Gastroesophageal Reflux Symptoms显示文摘 | Joel H. Rubenstein John M. Inadomi James Scheiman Philip Schoenfeld Henry Appelman Min Zhang Val Metko John Y. Kao | 2014 | Clinical Gastroenterology and Hepatology2014，，2： | 1 |
| 5 | Campylobacter pylori is not associated with gastroparesis显示文摘 | Dr. Jeffrey L. Barnett MD Elizabeth M. Behler Henry D. Appelman MD Grace H. Elta MD | 1989 | Digestive Diseases and Sciences1989，，11： | 1 |
| 6 | Inflammatory cloacogenic polyp: A unique inflammatory lesion of the anal transitional zone显示文摘 | Paul F. Lobert Henry D. Appelman | 1981 | The American Journal of Surgical Pathology1981，，8： | 1 |
| 7 | Stromal Tumors of the Anorectum: A Clinicopathologic Study of 22 Cases显示文摘 | Joseph A. Tworek John R. Goldblum Sharon W. Weiss Joel K. Greenson Henry D. Appelman | 1999 | The American Journal of Surgical Pathology1999，，8： | 1 |
| 8 | In Vivo Molecular Imaging of Barrett’s Esophagus With Confocal Laser Endomicroscopy显示文摘 | Matthew B. Sturm Cyrus Piraka B. Joseph Elmunzer Richard S. Kwon Bishnu P. Joshi Henry D. Appelman D. Kim Turgeon Thomas D. Wang | 2013 | Gastroenterology2013，，1： | 1 |
| 9 | Surgical Pathology of Crohn’s Disease显示文摘 | Celina G. Kleer Henry D. Appelman | 2001 | Surgical Clinics of North America2001，，1： | 1 |
| 10 | Loss of CDX2 Expression and Microsatellite Instability Are Prominent Features of Large Cell Minimally Differentiated Carcinomas of the Colon显示文摘 | Takao Hinoi Masachika Tani Peter C. Lucas Karel Caca Rodney L. Dunn Ettore Macri Massimo Loda Henry D. Appelman Kathleen R. Cho Eric R. Fearon | 2001 | The American Journal of Pathology2001，，6： | 1 |
| 11 | Affinity Peptide for Targeted Detection of Dysplasia in Barrett’s Esophagus显示文摘 | Meng Li Constantinos P. Anastassiades Bishnu Joshi Chris M. Komarck Cyrus Piraka Badih J. Elmunzer Danielle K. Turgeon Timothy D. Johnson Henry Appelman David G. Beer Thomas D. Wang | 2010 | Gastroenterology2010，，： | 1 |
| 12 | Achalasia: A Morphologic Study of 42 Resected Specimens显示文摘 | John R. Goldblum Richard I. Whyte Mark B. Orringer Henry D. Appelman | 1994 | The American Journal of Surgical Pathology1994，，4： | 1 |
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