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| 1 | Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。 | Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim | 2015 | Cell Research2015，25，6： | 20 |
| 2 | Combined transplantation of GDAs^(BMP) and hr-decorin in spinal cord contusion repair显示文摘Following spinal cord injury, astrocyte proliferation and scar formation are the main factors inhibiting the regeneration and growth of spinal cord axons. Recombinant decorin suppresses inflammatory reactions, inhibits glial scar formation, and promotes axonal growth. Rat models of T8 spinal cord contusion were created with the NYU impactor and these models were subjected to combined transplantation of bone morphogenetic protein-4-induced glial-restricted precursor-derived astrocytes and human recombinant decorin transplantation. At 28 days after spinal cord contusion, double-immunofluorescent histochemistry revealed that combined transplantation inhibited the early inflammatory response in injured rats. Furthermore, brain-derived neurotrophic factor, which was secreted by transplanted cells, protected injured axons. The combined transplantation promoted axonal regeneration and growth of injured motor and sensory neurons by inhibiting astrocyte proliferation and glial scar formation, with astrocytes forming a linear arrangement in the contused spinal cord, thus providing axonal regeneration channels. | Liang Wu Jianjun Li Liang Chen Hong Zhang Li Yuan Stephen JA Davies | 2013 | Neural Regeneration Research2013，8，24： | 6 |
| 3 | Factors Predictive of Adverse Events Following Endoscopic Papillary Large Balloon Dilation: Results from a Multicenter Series显示文摘 | Soo Jung Park Jin Hong Kim Jae Chul Hwang Ho Gak Kim Don Haeng Lee Seok Jeong Sang-Woo Cha Young Deok Cho Hong Ja Kim Jong Hyeok Kim Jong Ho Moon Sang-Heum Park Takao Itoi Hiroyuki Isayama Hirofumi Kogure Se Joon Lee Kyo Tae Jung Hye Sun Lee Todd H. Baron | 2013 | Digestive Diseases and Sciences2013，，4： | 2 |
| 4 | Ultrastruetual localization of vascular permeability factor/Vascular endothetial growth factor (VPF/VEGF)to the abluminal plasma membrane and vesiculovacuolar orga neUes of tumor microvascular endothelium 显示文摘 | Qu hong Nagy JA Senger DR | 1995 | J Histochem Cytochem1995，，： | 1 |
| 5 | CT bronchus sign in malignant solitary pulmonary lesions:value in the prediction of cell type显示文摘 | Choi JA Kim JH Hong KT | 2000 | Eur Radiol2000，10，10： | 1 |
| 6 | The inhibition of T-cells proliferation by mouse mesenchymal stem cells through the induction of pl6INK4A-cyclin D1/cdk4 and p21wafl, p27kipl- cyclin E/cdk2 pathways 显示文摘 | Kim JA Hong S Lee B | 2007 | Cell Immunol2007，245，1： | 1 |
| 7 | Synthesis and antifungal evalu- ation of 7-arylamino-5, 8-dioxo-5, 8-dihydroisoquinoline-4-car- hoxylates显示文摘 | RYU CK SONG AL HONG JA | 2013 | Bioorg Med Chem Lett2013，23，7： | 1 |
| 8 | In vitro differentiation of human umbilical cord blood-derived mesenchymal stem cells into hepatocyte-like cells 显示文摘 | Hong SH Gang EJ Jeong JA | 2005 | Biochem Biophys Res Commun2005，330，4： | 1 |
| 9 | The effect of surface-modified nano-hydroxyapatite on biocompatibility of poly( ε -caprolactone)/hydroxyapatite nanocomposites显示文摘 | Hong Jae Lee Sung Eun Kim Hyung Woo Choi Chan Woo Kim Kyung Ja Kim Sang Cheon Lee | 2007 | European Polymer Journal2007，，5： | 1 |
| 10 | Elevation of CRABP-I in the cerebrospinal fluid of patients with Moyamoya disease显示文摘 | Kim SK Yoo JI Cho BK Hong SJ Kim YK Moon JA | 2003 | Stroke2003，34，12： | 1 |
| 11 | Depletion of DNA methyhransferase 1 and/or DNA methyhransferase 3b mediates'growth arrest and apoptosis in lung and esophageal cancer and malignant pleural mesothelioma cells 显示文摘 | Kassis ES Zhao M Hong JA | 2006 | J Thorac Cardiovasc Surg2006，131，2： | 1 |
| 12 | In vitro differentiation of human umbilical cord blood-derived mesenchymal stem cells into hepatocyte-like ceils显示文摘 | Hong SH Gang E J Jeong JA | 2005 | Biochem Biophys Res Commun2005，330，4： | 1 |
| 13 | The inhibition of T-cells proliferation by mouse mesenchymal stem cells through the induction of p16^INK4A-cyclinD1/cdk4 and p21^Waf1, p27^kip1- cyclinE/cdk2 pathways显示文摘 | Kim JA Hong A Lee B | 2007 | Cellular Immunology2007，245，1： | 1 |
| 14 | Differentiation of human circulating fibrocytes as mediated by transforming growth factorbeta and peroxisome proliferator-activated receptor gamma 显示文摘 | Hong KM Belperio JA Keane MP | 2007 | J Biol Chem2007，282，22： | 1 |
| 15 | Passive smoking as a risk factor of anemia in young children aged 0 ~ 35 months in Jordan显示文摘 | Hong R Betaneourt JA Ruiz-Beltran M | 2007 | BMC Pediatr2007，7，1： | 1 |
| 16 | In vitro mesengenic potential of human umbilical cord blood-derived mesenchymal stem cells显示文摘 | Gang EJ Hong SH Jeong JA | | 0，，01： | 1 |
| 17 | MD-2 as the target of nonlipidchalcone in the inhibition of endotoxin LPS-induced TLR4activity显示文摘 | Roh E Lee HS Kwak JA Hong JT Nam SY Jung SH LeeJY Kim ND Han SB Kim Y | 2011 | J Infect Dis volume2011，203，： | 1 |
| 18 | Passive smoking as a risk factor of anemia in young children aged 0-35 months in Jordan 显示文摘 | Hong R Betancourt JA Ruiz-Beltran M | 2007 | BMC Pediair2007，7，： | 1 |
| 19 | Histologically proven non‐alcoholic fatty liver disease and clinically related factors in recipients after liver transplantation显示文摘 | Hyeyoung Kim Kyoungbun Lee Kwang‐Woong Lee Nam‐Joon Yi Hae Won Lee Geun Hong YoungRok Choi Tae You Suk‐Won Suh Ja June Jang Kyung‐Suk Suh | 2014 | Clin Transplant2014，，5： | 1 |
| 20 | ln vitro differentiation of human umbilical cord blood-derived mesenchymal stem ceils into hepatocyte- like cells显示文摘 | Hong SH Gang EJ Jeong JA | 2005 | Biochem Biophys Res Commun2005，330，4： | 1 |
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