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5篇 您的检索式:作者名="Hong Liling"
    题名 作者 年代 出处 被引量
1Differentiation of human adipose-derived stem cells into neuron-like cells by Radix Angelicae Sinensis显示文摘Human adipose tissues are an ideal source of stem cells.It is important to find inducers that can safely and effectively differentiate stem cells into functional neurons for clinical use.In this study,we investigate the use of Radix Angelicae Sinensis as an inducer of neuronal differentiation.Primary human adipose-derived stem cells were obtained from adult subcutaneous fatty tissue,then pre-induced with 10%Radix Angelicae Sinensis injection for 24 hours,and incubated in serum-free Dulbecco’s modified Eagle’s medium/Nutrient Mixture F-12 containing 40%Radix Angelicae Sinensis to induce its differentiation into neuron-like cells.Butylated hydroxyanisole,a common inducer for neuronal differentiation,was used as the control.After human adipose-derived stem cells differentiated into neuron-like cells under the induction of Radix Angelicae Sinensis for 24 hours,the positive expression of neuron-specific enolase was lower than that of the butylated hydroxyanisole-induced group,and the expression of glial fibrillary acidic protein was negative.After they were induced for 48 hours,the positive expression of neuron specific enolase in human adipose-derived stem cells was significantly higher than that of the butylated hydroxyanisole-induced group.Our experimental findings indicate that Radix Angelicae Sinensis can induce human adipose-derived stem cell differentiation into neuron-like cells and produce less cytotoxicity.Qiaozhi Wang Lile Zhou Yong Guo Guangyi Liu Jiyan Cheng Hong Yu 2013Neural Regeneration Research2013,8,35:3
2A potential mechanism of metformin-mediated regulation of glucose homeostasis: Inhibition of Thioredoxin-interacting protein (Txnip) gene expression显示文摘Tin Fan Chai Shin Yee Hong Hongpeng He Liling Zheng Thilo Hagen Yan Luo Fa-Xing Yu 2012Cellular Signalling2012,,8:1
3The dynamic profile and potential function of B-cell subsets during pregnancy显示文摘As the main antibody-producing and antigen-presenting cells,B cells play critical roles in autoimmune diseases,tumors,and transplantation.Recently,the immunoregulatory functions of B cells have attracted attention and have been extensively studied in these fields.Liling Wang Panpan Jiang Sijia Zhao Hong Liu Liping Liu Gil Mor Chaohong Liu Aihua Liao 2021Cellular & Molecular Immunology2021,18,4:1
4Antiproliferative constituents from Gynura divaricata subsp, formosana 显示文摘Chen Shengchi Hong Liling Chang Chungyang 2003Chin Pharm J2003,55,2:1
5AF9YEATS结构域在分子层面偶联组蛋白巴豆酰化和活跃转录显示文摘染色质结合蛋白质模块(“阅读器”)识别组蛋白共价修饰构成表观遗传调控的主要方式之一,例如溴域识别乙酰化赖氨酸修饰。除乙酰化之外,近来研究发现组蛋白赖氨酸还能发生巴豆酰化、丁酰化、丙酰化等酰基化修饰.但能够偏好识别这些新型酰基化修饰的阅读器尚未见报道。Yuanyuan Li Benjamin R.Sabari Tatyana Panchenko Hong Wen Dan Zhao Haipeng Guan Liling Wan He Huang Zhanyun Tang Yingming Zhao Robert G.Roeder Xiaobing Shi C.David Allis 李海涛 2017科学新闻2017,19,4:0
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