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| 1 | Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD. | Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele | 2009 | World Journal of Gastroenterology2009，15，10： | 20 |
| 2 | Primary amyloidosis of the breast presenting as a solitary nodule:case report and review of the literature显示文摘 | Huerter ME Hammadeh R Zhou Q | 2014 | Ochsner J2014，14，2： | 1 |
| 3 | Recurrent angiomatoid fibrous histiocytoma a ease report and review of the literature 显示文摘 | Huerter ME Hammadeh R Zhou Q et ul | 2014 | Ochsner J2014，14，3： | 1 |
| 4 | Sinusitis and gastroesophageal reflux disease显示文摘 | DiBaise JK Huerter JV Quigley EM | 1998 | Ann Int Med1998，129，2： | 1 |
| 5 | Role of GERD in chronic resistant sinusitis :a prospective,open label, pilot trial显示文摘 | Dibaise JK Olusola BF Huerter JV | 2002 | Am J Gastroente rol2002，97，4： | 1 |
| 6 | Migraine aura 显示文摘 | Cutrer FM Huerter K | 2007 | Neurologist2007，13，： | 1 |
| 7 | Implications of combined ovariectomy and glucocorticoid (dexamethasone) treatment on mineral, microarchitectural, biomechanical and matrix properties of rat bone显示文摘 | Parameswari Govindarajan Thaqif Khassawna Marian Kampschulte Wolfgang B?cker Britta Huerter Lutz Dürselen Miriam Faulenbach Christian Heiss | 2013 | Int J Exp Path2013，，6： | 1 |
| 8 | A case of human orf contracted from a deer 显示文摘 | Kuhl J T Huerter C J Hashish H | 2003 | Cutis2003，71，4： | 1 |
| 9 | Migraine aura显示文摘 | Cutrer FM Huerter K | 2007 | Neurologist2007，13，： | 1 |
| 10 | Sinusitis and gas-troesophageal reflux disease显示文摘 | Di Baise JK Huerter JV Quigley EM | | 0，，12： | 1 |
| 11 | Sinusitis and gas - troesoph- ageal reflux disease 显示文摘 | Di Baise JK Huerter JV Quigley EM | 1998 | Ann Intern Med1998，129，12： | 1 |
| 12 | Sinusitis and gastroesophageal reflux disease 显示文摘 | DiBaise JK Huerter JV Quigley EM | 1998 | Ann Intern Med1998，129，12： | 1 |
| 13 | Role of GERD in chronic resistant sinusitis, a prospective, open label, pilot trial显示文摘 | DiBaise JK Olusola BF Huerter JV | 2002 | Am J Gastroenterol2002，97，4： | 1 |
| 14 | Exertional headache and coronary ischemia despite nor- mal electrocardiographic stress testing显示文摘 | Cutrer FM Huerter K | 2006 | Headache2006，46，1： | 1 |
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