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| 1 | Colonoscopy-induced ischemic colitis in patients without risk factors显示文摘Ischemic colitis is the most common form of intestinal ischemia.It is a condition that is commonly seen in the elderly and among individuals with risk factors for ischemia.Common predisposing conditions for ischemic colitis are major vascular occlusion,small vessel disorder,shock,some medications,colonic obstructions and hematologic disorders.Ischemic colitis following colonoscopy is rare.Here,we report two cases of ischemic colitis after a routine screening colonoscopy in patients without risk factors for ischemia. | Sang Ok Lee Sae Hee Kim Sung Hee Jung Chan Woong Park Min Ji Lee Jin A Lee Hyun Cheol Koo Anna Kim Hyun-Young Han Dong-Wook Kang | 2014 | World Journal of Gastroenterology2014,20,13: | 9 |
| 2 | Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells显示文摘 | Saiyong Zhu Raiesh Ambasudhan Woong Sun Hyun Jung Kim Maria Talantova Xiaojing Wang Mingliang Zhang Yu Zhang Timothy Laurent James Parker Han-Seop Kim Jeffrey D Zaremba Sofiyan Saleem Sara Sanz-Blasco Eliezer Masliah Scott R McKercher Yee Sook Cho Stuart A Lipton Janghwan Kim Sheng Ding | 2014 | Cell Research2014,24,1: | 6 |
| 3 | Effect of trapping vascular endothelial growth factor-A in a murine model of dry eye with inflammatory neovascularization显示文摘·AIM: To evaluate whether trapping vascular endothelial growth factor-A(VEGF-A) would suppress angiogenesis and inflammation in dry eye corneas in a murine corneal suture model.·METHODS: We established two groups of animals, one with non-dry eyes and the other with induced dry eyes.In both groups, a corneal suture model was used to induce inflammation and neovascularization. Each of two groups was again divided into three subgroups according to the treatment; subgroup I(aflibercept),subgroup II(dexamethasone) and subgroup III(phosphate buffered saline, PBS). Corneas were harvested and immunohistochemical staining was performed to compare the extents of neovascularization and CD11b+ cell infiltration. Real-time polymerase chain reaction was performed to quantify the expression of inflammatory cytokines and VEGF-A in the corneas.·RESULTS: Trapping VEGF-A with aflibercept resulted in significantly decreased angiogenesis and inflammation compared with the dexamethasone and PBS treatments in the dry eye corneas(all P <0.05), but with no such effects in non-dry eyes. The anti-inflammatory and antiangiogenic effects of VEGF-A trapping were stronger than those of dexamethasone in both dry eye and non-dry eye corneas(all P <0.05). The levels of RNA expression of VEGF-A, TNF-alpha, and IL-6 in the aflibercept subgroup were significantly decreasedcompared with those in the PBS subgroup in the dry eye group.·CONCLUSION: Compared with non-dry eye corneas,dry eye corneas have greater amounts of inflammation and neovascularization and also have a more robust response to anti-inflammatory and anti-angiogenic agents after ocular surface surgery. Trapping VEGF-A is effective in decreasing both angiogenesis and inflammation in dry eye corneas after ocular surface surgery. | Jin Woo Kwon Jin A Choi Eun Young Shin Tae Yoon La Dong Hyun Jee Yeon Woong Chung Yang Kyung Cho | 2016 | International Journal of Ophthalmology(English edition)2016,9,11: | 5 |
| 4 | Comparison of postoperative corneal changes between dry eye and non-dry eye in a murine cataract surgery model显示文摘AIM: To compare the effects of the surgical insult of cataract surgery on corneal inflammatory infiltration,neovascularization(NV) and lymphangiogenesis(LY)between the dry eye and non-dry eye in murine cataract surgery models.·METHODS: We established two groups of animals, one with normal eyes(non-dry eye) and the second with induced dry eyes. In both groups, we used surgical insults to mimic human cataract surgery, which consisted of lens extraction, corneal incision and suture.After harvesting of corneas on the 9th postoperative day and immunohistochemical staining, we compared NV, LY and CD11b+ cell infiltration in the corneas.· RESULTS: Dry eye group had significantly more inflammatory infiltration(21.75%±7.17% vs 3.65%±1.49%;P =0.049). The dry eye group showed significantly more NV(48.21% ±4.02% vs 26.24% ±6.01%; P =0.016) and greater levels of LY(9.27%±0.48% vs 4.84%±1.15%; P =0.007). In corneas on which no surgery was performed,there was no induction of NV in both the dry and non-dry group, but dry eye group demonstrated more CD11b+cells infiltration than the non-dry eye group(0.360% ±0.160% vs 0.023% ±0.006%; P =0.068). Dry eye group showed more NV than non-dry eye group in both topical PBS application and subconjunctival PBS injection(P =0.020 and 0.000, respectively).·CONCLUSION: In a murine cataract surgery model,preexisting dry eye can induce more postoperative NV,LY, and inflammation in corneal tissue. | Jin Woo Kwon Yeon Woong Chung Jin A Choi Tae Yoon La Dong Hyun Jee Yang Kyung Cho | 2016 | International Journal of Ophthalmology(English edition)2016,9,2: | 5 |
| 5 | Caveolin 1 Expression Correlates with Poor Prognosis and Focal Adhesion Kinase Expression in Gastric Cancer显示文摘 | Nam Kyung Han Lee Byung Lan Park Joo Hyun Kim Jin Han Nayoung Lee Hee Eun Kim Min A Lee Hye Seung Kim Woo Ho | 2012 | Pathobiology2012,,2: | 2 |
| 6 | Simulation model for electron irradiated IGZO thin film transistors显示文摘An efficient drain current simulation model for the electron irradiation effect on the electrical parameters of amorphous In–Ga–Zn–O(IGZO) thin-film transistors is developed. The model is developed based on the specifications such as gate capacitance, channel length, channel width, flat band voltage etc. Electrical parameters of un-irradiated IGZO samples were simulated and compared with the experimental parameters and 1 kGy electron irradiated parameters. The effect of electron irradiation on the IGZO sample was analysed by developing a mathematical model. | G K Dayananda C Shantharama Rai A Jayarama Hyun Jae Kim | 2018 | Journal of Semiconductors2018,39,2: | 2 |
| 7 | Experimental study on natural convection heat transfer from horizontal cylinders with longitudinal plate fins 显示文摘 | HYUN J K BYOUNG H A JINIL P | 2013 | Mechanical Science and Technology2013,27,2: | 1 |
| 8 | Distinctive features of angiogenesis and lymphangiogenesis determine their functionality during de novo tumor development 显示文摘 | Eichten A Hyun WC Coussens LM | 2007 | Cancer Res2007,67,11: | 1 |
| 9 | Water purification by TiO2 powder显示文摘 | KIN DONG HYUN ANDERSON MARC A | 1994 | Environ Sci Technol1994,28,2: | 1 |
| 10 | Microstamping on an activated polymer surface: Patterning biotin and streptavidin onto common polymeric biomaterials显示文摘 | HYUN J ZHU Y LIEBMANN-VINSON A | 2001 | Langmuir2001,17,20: | 1 |
| 11 | 显示文摘 | Lee I J Hyun SW Nandi A | 2003 | Am J Physiol Lung Cell Mol Physiol2003,284,1: | 1 |
| 12 | Effect of Post-Oxidizing Time on Corrosion Properties of Plasma Nitrocarburized AISI 1020Steel显示文摘 | Kou Hyun Lee a Ki Suk Nama Pyung Woo Shin | 2003 | Materials Letters2003,57,: | 1 |
| 13 | Preparation and Characterization of Composites Based on Polylactic Acid and Beeswax with Improved Water Vapor Barrier Properties显示文摘 | Jung Hoon Lim Jeong Ae Kim Jung A Ko Hyun Jin Park | 2015 | Journal of Food Science2015,,: | 1 |
| 14 | Block copolymer compatibilization of co-continuous polymer blends显示文摘 | JEFFREY A GALLOWAY HYUN K JEON JOEL R BELL | 2005 | Polymer2005,46,: | 1 |
| 15 | Fabrication of CdS nanowires decorated with TiO2 nanoparticles for photocatalytic hydrogen production under visible light irradiation显示文摘 | Jang Jum Suk Kim Hyun Gyu Joshi Upendra A | 2008 | International Journal of Hydrogen Energy2008,33,21: | 1 |
| 16 | miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARγ expression显示文摘 | Sang Yun Kim A Young Kim Hyun Woo Lee You Hwa Son Gha Young Lee Joo-Won Lee Yun Sok Lee Jae Bum Kim | 2010 | Biochemical and Biophysical Research Communications2010,,: | 1 |
| 17 | Quantification of ammonia-oxidizing bacteria and factors controlling nitrification in salt marsh sediment 显示文摘 | Dollhopf S L Hyun J H Smith A C | 2005 | Appl Environ Microbiol2005,71,: | 1 |
| 18 | Patterning Cells in Highly Deformable Microstructures: Effect of Plastic Deformation of Substrate on Cellular Phenotype and Gene Expression显示文摘 | Hyun J H Chen J S Lori A | 2006 | Biomaterials2006,27,8: | 1 |
| 19 | Ethylbenzene removal in a multiple-stage biofilter显示文摘 | Hyun K S Bradley A S | 2001 | Air Waste Manag Assoc2001,51,12: | 1 |
| 20 | Role of IL-17A in the develop- ment of colitis-associated cancer aintestinal tumorigenesis 显示文摘 | Y S Hyun D SHan A R Lee | 2010 | Proc Natl Acad Sci U S A2010,107,12: | 1 |