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| 1 | Global myocardial strain assessment by different imaging modalities to predict outcomes after ST-elevation myocardial infarction:A systematic review显示文摘AIM: To conduct a systematic review relating myocardial strain assessed by different imaging modalities for prognostication following ST-elevation myocardial infarction(STEMI).METHODS: An online literature search was performed in Pub Med and OVID® electronic databases to identify any studies that assessed global myocardial strain parameters using speckle-tracking echocardiography(STE) and/or cardiac magnetic resonance imaging(CMR) techniques [either myocardial tagging or feature tracking(FT) software] in an acute STEMI cohort(days 0-14 post-event) to predict prognosis [either development of major adverse cardiac events(MACE)] or adverse left ventricular(LV) remodelling at follow-up(≥ 6 mo for MACE,≥ 3 mo for remodelling). Search was restricted to studies within the last 20 years. All studies that matched the pre-defined search criteria were reviewed and their results interpreted. Due to considerable heterogeneity between studies,metaanalysis was not performed.RESULTS: A total of seven studies(n = 7) were identified that matched the search criteria. All studies used STE to evaluate strain parameters- five(n = 5) assessed global longitudinal strain(GLS)(n = 5),one assessed GLS rate(GLS-R)(n = 1) and one assessed both(n = 1). Three studies showed that GLS independently predicted the development of adverse LV remodelling by multivariate analysis- odds ratio between 1.19(CI: 1.04-1.37,P < 0.05) and 10(CI: 6.7-14,P < 0.001) depending on the study. Four studies showed that GLS predicted the development of MACE- hazard ratio(HR) between 1.1(CI: 1-1.1,P = 0.006) and 2.34(1.10-4.97,P < 0.05). One paper found that GLS-R could significantly predict MACEHR 18(10-35,P < 0.001)- whilst another showed it did not. GLS <-10.85% had sensitivity/specificity of 89.7%/91% respectively for predicting the development of remodelling whilst GLS <-13% could predict the development of MACE with sensitivity/specificity of 100%/89% respectively. No suitable studies were identified that assessed global strain by CMR tagging or FT techniques.CONCLUSION: GLS measured acutely post-STEMI by STE is a predictor of poor prognosis. Further research is needed to show that this is true for CMR-based techniques. | Abhishek Shetye Sheraz A Nazir Iain B Squire Gerald P McCann | 2015 | World Journal of Cardiology2015，7，12： | 2 |
| 2 | The IgA system: a comparison of structure and function in different species显示文摘 | Veerle S Iain R P | 2006 | Vet Res2006，，37： | 1 |
| 3 | Biomedical research: increasing value, reducing waste显示文摘 | Malcolm R Macleod Susan Michie Ian Roberts Ulrich Dirnagl Iain Chalmers John P A Ioannidis Rustam Al-Shahi Salman An-Wen Chan Paul Glasziou | 2014 | The Lancet . 2014 (9912)2014，，9912： | 1 |
| 4 | Talking Trash:Legitimacy,Impression Management and Unsystematic Risk in the Context of the Natural Environmen 显示文摘 | Bansal P Iain C | 2004 | Academy of Management Journal2004，，47： | 1 |
| 5 | Optimisation of the two-dimensional gel electrophoresis protocol using the Taguchi approach显示文摘 | Guennadi A K Iain M P Julian B J | 2004 | Proteome Science2004，，2： | 1 |
| 6 | Analysis of mechanical systems using interval computations applied to finite element methods 显示文摘 | Dessombz O Thouverez F Iaine J P | 2001 | Journal of Sound and Vibration2001，239，5： | 1 |
| 7 | C-reactive protein concentration in children: relationship to adiposity and other cardiovascular risk factors显示文摘 | Derek G Cook Mike A Mendall Peter H Whincup Iain M Carey Lydia Ballam Julia E Morris George J Miller David P Strachan | 2000 | Atherosclerosis2000，，1： | 1 |
| 8 | Natural history of mesenchymal stem cells, from vessel walls to culture vessels显示文摘 | Iain R. Murray Christopher C. West Winters R. Hardy Aaron W. James Tea Soon Park Alan Nguyen Tulyapruek Tawonsawatruk Lorenza Lazzari Chia Soo Bruno Péault | | Cellular and Molecular Life Sciences0，，8： | 1 |
| 9 | Potent vasorelaxant activity of the TMEM16A inhibitor T16Ainh‐A01显示文摘 | Alison J Davis Jian Shi Harry AT Pritchard Preet S Chadha Normand Leblanc Georgios Vasilikostas Zhen Yao AS Verkman Anthony P Albert Iain A Greenwood | 2013 | Br J Pharmacol2013，，3： | 1 |
| 10 | Generation of high-affinity chicken single-chain Fv antibody fragments for measurement of the pseudonitzschia pungens toxin domoic 显示文摘 | William J J F Iain S Joanna P R | 2006 | Acid applied And Environmental Microbiology2006，，： | 1 |
| 11 | Understanding the roles of registered general nurses and care assistants in UK nursing home显示文摘 | Michelle P Iain C David C | | 0，，05： | 1 |
| 12 | An SNF2 Protein associated with nuclear RNA silencing and the spread of a silencing signal between cells in Arabidopsis显示文摘 | Lisa M S Olga P Iain S | 2007 | Plant Cell2007，19，： | 1 |
| 13 | The influence of controlled release fertilizersand the form of applied fertilizer nitrogen on nitrous oxide emis-sions from an andosol 显示文摘 | IAIN P HARUO T | 2003 | Nutrient Cycling in Agroecosystems2003，67，： | 1 |
| 14 | The role of P2X7 in pain and inflammation显示文摘 | Jane P Hughes Jonathan P Hatcher Iain P Chessell | 2007 | Purinergic Signalling (-)2007，，1： | 1 |
| 15 | Thermoregulatory behavior of the crayfish Procambarus clarkii in a burrow environment显示文摘 | Aaron L P Iain J M | 2003 | Comparative Biochemistry and Physiology Part A2003，136，： | 1 |
| 16 | The influence of controlled release fertilisers and the form of applied fertiliser nitrogen on nitrous oxide emissions from an andosol 显示文摘 | Iain P McTaggart Haruo Tsuruta | 2003 | Nutrient Cycling in Agroecosystems2003，67，1： | 1 |
| 17 | Assessing the quality of re- search显示文摘 | Paul G Vandenbroucke J P Iain C | 2004 | BMJ2004，328，7430： | 1 |
| 18 | Thermoregulatory behavior of the crayfish (Procambarus clarkii) in a burrow environment 显示文摘 | Aaron L P Iain J M | 2003 | Comp Biochem Physiol A2003，136，： | 1 |
| 19 | Carbon and nitrogen stable isotope analysis of three types of oyster tissue in an impact-ed estuary 显示文摘 | Richard F P Stephanie K M Iain M S | 2006 | Estuarine Coastal and Shelf Science2006，66，： | 1 |
| 20 | A chemokine-like viral protein enhances alpha interferon production by plasmacytoid dendritic ceils but delays C D8+T Cell activation and impairs viral clearance 显示文摘 | Wikstrom M E Fleming P Iain C | 2013 | Journal of Virology2013，87，14： | 1 |
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