|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Weekly docetaxel and gemcitabine in previously treated metastatic esophageal squamous cell carcinoma显示文摘AIM: To assess the efficacy and safety of weekly docetaxel plus a fixed-dose rate(FDR) of gemcitabine in metastatic esophageal squamous cell carcinoma(SCC).METHODS: A multi-center, open-label, prospective phase Ⅱ study was designed.Thirty-three esophageal SCC patients with documented progression after fluoropyrimidine/platinum-based first-line chemotherapy were enrolled and treated with docetaxel 35 mg/m2 and gemcitabine 1000 mg/m2 iv at a FDR(10 mg/m2 per minute) on days 1 and 8.Treatment was repeatedevery twenty-one days until disease progression, unacceptable toxicity, or consent withdrawal.The primary endpoint was response rate(RR), and secondary endpoints were safety, progression-free survival(PFS) and overall survival(OS).RESULTS: Combination of weekly docetaxel and FDR gemcitabine was well tolerated: the most common treatment-related adverse events were anemia(97%), fatigue(64%) and neutropenia(55%).One patient with multiple lung and lymph node metastases died of respiratory failure after receiving four cycles of chemotherapy, and the possibility of drug-induced pneumonitis could not be completely excluded.Disease control(objective response plus stable disease) in the ITT population was achieved in 88% of patients, and the overall RR was 30%(95%CI: 15%-46%).The median PFS and OS were 4.0(95%CI: 3.4-4.6) and 8.8 mo(95%CI: 7.8-9.8 mo), respectively.CONCLUSION: A combination of weekly docetaxel and FDR gemcitabine showed promising antitumor activity and tolerability in previously treated, metastatic esophageal SCC. | Min-Young Lee Ki Sun Jung Hae Su Kim Ji Yun Lee Sung Hee Lim Moonjin Kim Hyun Ae Jung Sung Min Kim Jong Mu Sun Myung-Ju Ahn Jeeyun Lee Se Hoon Park Seong Yoon Yi In Gyu Hwang Sang-Cheol Lee Hee Kyung Ahn Do Hyoung Lim Soon Il Lee Keon Woo Park | 2015 | World Journal of Gastroenterology2015，21，14： | 2 |
| 2 | Effects of social anxiety on non verbal accuracy and response time: facial expression 显示文摘 | Mu 11 ins D T Duke M P | 2004 | Journal of Nonverbal Behavior2004，28，1： | 1 |
| 3 | Audit Qualification and Timing of Earnings Announcements : Evidence from China 显示文摘 | Haw In - Mu G Park Kyungjoo Qi Da- qing Wu Woody | 2003 | Auditing: A Journal of Practice & Theory2003，22，2： | 1 |
| 4 | 'True' anti mit ochon-drial anti body-negative primary biliary cirrhos is, low sen- sitivity of the routine assays, or both? 显示文摘 | Mu ratori P M uratoriL Gershw in ME | 2004 | Clin Exp Immuno2004，135，1： | 1 |
| 5 | Prevalence of mixed hypertension, isolated systolic hypertension and isolated diastolic hypertension in the elderly population in the community显示文摘 | Ekpo EB Ashworeh IN Fernando MU | 1994 | J Hum Hypertens1994，8，： | 1 |
| 6 | Preservative treatment of wood - based composites with 3 - iodo - 2 - propynyl bu- tylcarbamate using super - critical carbon dioxide impreg- nation 显示文摘 | MU IN M TSUNODAK | 2003 | J Wood Sci2003，49，： | 1 |
| 7 | Feasibility of supercritical carbon dioxide as a carrier solvent for preservative treat- ment of wood - based composites 显示文摘 | MU IN M TSUNODA K | 2003 | J Wood Sci2003，49，： | 1 |
| 8 | The effects of hypebaric oxyegen on free flaps in rats 显示文摘 | Knelim Cm In MU Myers RA | 1990 | Arch Surg1990，125，5： | 1 |
| 9 | Timeliness of Annual Report Releases and Market Reaction to Earnings Announcements in an Emerging Capital Market:The Case of China 显示文摘 | Haw In - Mu Daqing Qi Woody Wu | 2000 | Journal of International Financial Management & Accounting2000，11，2： | 1 |
| 10 | Esophageal cancer: pneumo-64-MDCT显示文摘 | Marina Ulla Demetrio Cavadas Inés Mu?oz Axel Beskow Alberto Seehaus Ricardo García-Mónaco | 2010 | Abdominal Imaging2010，，4： | 1 |
| 11 | Immunolocalization of Pit-1 in gonadotroph nuclei is indicative of the transdifferentiation of gonadotroph to lactotroph cells in prolactinomas induced by estrogen显示文摘 | Jorge Humberto Mukdsi Ana Lucía Paul Sonia Mu?oz Agustín Aoki Alicia Inés Torres | 2004 | Histochemistry and Cell Biology2004，，6： | 1 |
| 12 | Less anterior knee pain with a mobile-bearing prosthesis compared with a fixed-bear- ing prosthesis 显示文摘 | Breugem SJ Siereveh IN Schafroth MU | 2008 | Clin Orthop Relat Res2008，466，8： | 1 |
| 13 | Less an-terior knee pain with a mobile-bearing prosthesis com-pared with a fixed-bearing prosthesis 显示文摘 | Breugem SJ Sierevelt IN Schafroth MU ei al | 2008 | Clin OrthopRelat Res2008，，466： | 1 |
| 14 | Application of bronchoscopic Argon plasma coagulation in the treatment of tumorous endobronchial tuberculosis:Historical controlled trial显示文摘 | IN F MU D XIE Y | 2013 | J Thorac Cardiovasc Surg2013，145，6： | 1 |
| 15 | Less anterior knee pain with a mobile-bearing prosthesis compared with a fixed-bearing prosthesis显示文摘 | Breugem SJ Sierevelt IN Schafroth MU | 2008 | Clin Orthop2008，466，： | 1 |
| 16 | 微小RNA介导的治疗调节血脑屏障破坏,改善血管性认知功能障碍显示文摘目前,还没有有效的治疗方法来预防与血管性认知功能障碍相关的痴呆症。微小RNA(microRNA)在转录后水平调节基因表达并在血管疾病中起关键作用。肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)通过修饰脑血管紧密连接调节血脑屏障破坏。 | 刘莉 叶鹏 Toyama K Spin JM Deng AC Huang TT Wei K Wagenhuser MU Yoshino T Nguyen H Mulorz J Kundu S Raaz U Adam M Schellinger IN Jagger A Tsao PS | 2018 | 中华高血压杂志2018，26，6： | 1 |
| 17 | Radiofrequency ablation of benign symptomatic thyroid nodules: prospec- tive safety and efficacy study显示文摘 | Ugurlu MU Uprak K Akpinar IN | 2015 | World J Surg2015，39，4： | 1 |
| 18 | Child neglect in one-child fami- lies from Suzhou city of mainland, China 显示文摘 | JING H ZHE MU BRIGHT IN | 2014 | BMC Int Health Human Rights2014，14，： | 1 |
| 19 | Market consequences of earnings management in response to security regulations in China显示文摘 | Haw In -Mu Daqing Qi Donghui Wu Woody Wu | 2005 | Contemporary Accounting Research (Spring)2005，22，1： | 1 |
| 20 | Arthroscopic Hybrid Fixation of a Tibial Eminence Fracture in Children显示文摘 | Jong In Kim Jae Ho Kwon Dong Hyun Seo Shaishav M. Soni Michael Mu?oz Kyung Wook Nha | 2013 | Arthroscopy Techniques2013，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员