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| 1 | Ganglion cells apoptosis in diabetic rats as early prediction of glaucoma:a study of Brn3b gene expression and association with change of quantity of NO, caspase-3, NF-κB, and TNF-α显示文摘AIM:To find a new concept to show whether or not apoptosis of retinal ganglion cells(RGCs)canbe determined in the histology of acute hyperglycemia in the role of expressed Brn3b gene related to nitric oxide(NO),caspase-3,nuclear factor kappa-B(NF-κB),and tumor necrosis factor-α(TNF-α)as an early predictor of primary open angle glaucoma(POAG)eyes and their associations.METHODS:Experimental in vivo study was carried out using adult male,white Sprague-Dawley rats aged≥2 mo,weighing 150-200 g.The animals were divided into two groups,one group receiving intraperitoneal injection of streptozotociz 50 mg/kg in 0.01 mol/L citricbuffer and p H 4.5 and a comparison made with the control group.Retinal tissue was divided into two parts(both experimental and control groups respectively):a)right retina for immunohistochemistry(IHC;caspase-3 and TNF-α);b)left retina was divided into two parts for the purpose of real-time polymerase chain reaction(PCR)test(RNA extraction for Brn3b gene expression analysis)and ELISA test(NO and NF-κB).RESULTS:The experimental group showed a decrease in Brn3b gene expression compared to the control group(1.3-fold lower in 2nd month;1.1-fold lower in 4th month and 2.5-fold lower in 6th month).However,there was a decrease of NO,caspase-3,and an increase of NF-κB and TNF-αquantity.CONCLUSION:The expression of m RNA Brn3b gene is inversely proportional to apoptosis in RGCs.The quantity of NO,caspase-3,NF-κB and TNF-αis influential in expression of Brn3b in RGCs caused by hyperglycemia in diabetic rats. | Irwan Tjandra Purnomo Soeharso Widya Artini Nurjati Chairani Siregar Andi Arus Victor | 2020 | International Journal of Ophthalmology(English edition)2020，13，12： | 2 |
| 2 | 记忆实践:重建记忆场所的混合城中村显示文摘理论命题THEORETICAL PROPOSITION导言Introduction区域化和全球化依然是21世纪争论的话题,特别是在亚洲的发展中地区,这些地区的高速城市化受欧洲和北美现代城市的影响。《变化》书中阐明的"罗马操作系统"成为西方现代城市的普适原则,也成为扩散到全球大城市的模型。亚洲的古老城市如北京、 | Irwan Soetikno 陈风 | 2013 | 北京规划建设2013，，2： | 2 |
| 3 | Self-care practices and health-seeking behavior among older persons in a developing country:Theories-based research显示文摘Purpose:The aim of this study was to examine the self-care practices and health-seeking behaviours of older adults in urban Indonesia.Methods:The cross-sectional study was performed from January to March 2014 in the Tammua sub-district of Indonesia.At the time of the study,273 older adults resided in Tammua,and half of them(51.2%)participated in this study.Data collection was carried out including self-care practices,health literacy,self-efficacy and basic conditioning factors.Results:It was found that most respondents(124;88.6%)always ate various protein sources daily.However,many participants never limited consumption of sugar(55;39.3%)or salt(40;28.6%),and more than half of respondents(96;68.6%)did not regularly visit MHCs.Health status(p<0.05),health maintenance(p<0.01)and salt limitation(p<0.05)were all significantly associated with salt limitation.It was found that respondents with higher selfefficacy,those who did not want to get information,and those of younger ages are less likely to visit MHCs regularly.Conclusion:An understanding of self-care practices and self-efficacy is needed to improve health care in developing countries.High self-efficacy should be promoted along with adequate health literacy.Older persons should learn the importance of regular health examinations to promote health,prevent diseases,and slow the progress of chronic diseases.The number of respondents who never limit their sugar and salt intake was especially surprising.An intervention program should be developed to limit salt and sugar intake of Indonesian elderly and to motivate older persons to use primary health services. | Andi Masyitha Irwan Mayumi Kato Kazuyo Kitaoka Teruhiko Kido Yoshimi Taniguchi Miho Shogenji | 2016 | International Journal of Nursing Sciences2016，3，1： | 2 |
| 4 | Acetone-initiated photografting of methacrylic acid on low-density polyethylene film in water solvent显示文摘 | IRWAN G S KONDO T | 2000 | European Polymer J2000，36，： | 1 |
| 5 | Image Quality in Reduced-Dose Coronary CT Angiography显示文摘 | Gagarina NV Irwan K Gordina G | 2011 | Acad Radiol2011，18，： | 1 |
| 6 | Introduction of stimuli-responsive polymers into regenerated cellulose film by means of photographing 显示文摘 | Irwan G S Kuroda S I Kubota H | 2001 | European Polymer Journal2001，37，： | 1 |
| 7 | Correlation of proton MR spectroscopy and diffusion tensor imaging 显示文摘 | Irwan R Sijens PE Potze JH | 2005 | Magnetic Resonance Imaging2005，23，： | 1 |
| 8 | Visual analogue scales:a source of erro显示文摘 | Snow S K irwan J R | 1988 | Ann Rheum Dis1988，47，6： | 1 |
| 9 | Characteristics of acrylic acid-grafted polyethylene prepared by photografting using mixed solvents consisting of water and organic solvent显示文摘 | IRWAN G S AOYAMA Y KURODA S I | 2004 | European Polymer Journal2004，40，1： | 1 |
| 10 | Online preconcentration of arsehie compounds by dynamic pH junction-capillary electrophoresis 显示文摘 | JAAFAR J IRWAN Z AHAMAD R | 2007 | J Sep Sci2007，30，3： | 1 |
| 11 | Analysis of the human brain in primary progressive multiple sclerosis with mapping of the spatial distributions using 1H MR spectroscopy and diffusion tensor imaging显示文摘 | Irwan R Sijens PE Potze JH | 2005 | Eur Radiol2005，15，： | 1 |
| 12 | Acetone initiated photografting of methacrylic acid on low-density polyethylene film in water solvent 显示文摘 | Zhao Liqun Irwan G S Kondo T | 2000 | Eur Polym J2000，36，8： | 1 |
| 13 | Polycyclic Aromatic Hydrocarbons in the Sediments of the Milwaukee Harbor Estuary, Wisconsin, U.S.A.显示文摘 | An Li Irwan A. Ab Razak Fan Ni Michael F. Gin Erik R. Christensen | 1998 | Water Air and Soil Pollution (-)1998，，1： | 1 |
| 14 | Al2O3-coated nanoporous TiO2 electrode for solid-state dye-sensitized solar cell 显示文摘 | Zhang X T Irwan S Taketo T | 2003 | Solar Energy Mater Solar Cells2003，80，： | 1 |
| 15 | Correlation of proton MR spec- troscopy and diffusion tensor imaging显示文摘 | Irwan R Sijens PE Potze JH | 2005 | Magnetic Resonance Ima- ging2005，23，8： | 1 |
| 16 | Test of Shear Transfer Enhancement in Symmetric Cold- formed Steel-concrete Composite Beams显示文摘 | IRWAN J M HANIZAH A H AZMI I | 2009 | Journal of Constructional Steel Research2009，65，12： | 1 |
| 17 | Assessment of the variations in fat content in normal liver,using a fast MR imaging method in comparison with results obtained by spectroscopic imaging显示文摘 | IRWAN R EDENS MA SUENS PE | 2008 | Eur Radiol2008，18，4： | 1 |
| 18 | Test of shear transfer enhancement in symmetric cold-formed steel- concrete composite beams 显示文摘 | IRWAN J M HANIZAH A H AZMI I | 2009 | Journal of Constructional Steel Research2009，65，12： | 1 |
| 19 | Large- scale test of symmetric cold-formed steel (CFS)-concrete composite beams with BTTST enhancement 显示文摘 | IRWAN J M HANIZAH A H AZMI I | 2011 | Journal of Constructional Steel Research2011，67，4： | 1 |
| 20 | Image quality in reduced-dose coronary CT angiography 显示文摘 | Gagarina NV Irwan R Gordina G | 2011 | Acad Radiol2011，18，8： | 1 |
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