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| 1 | Comparative prospective study between medial and lateral distal tibial locking compression plates for distal third tibial fractures显示文摘 | Sandeep Garg Vikram Khanna Mahaveer Prashad Goyal Narendra Joshi Amrut Borade Ishan Ghuse | 2017 | Chinese Journal of Traumatology2017，20，3： | 8 |
| 2 | A rare case of Staphylococcus lugdunensis septicemia associated with myocarditis and atrioventricular block显示文摘Myocarditis is a relatively rare,possibly life-threatening disease characterized by the inflammation of the myocardium.111 The disease pathogenesis is primarily initiated by acute injury and necrosis of cardiomyocytes,leading to an inflammatory response mediated by the immune system that can potentially cause further aggravation of myocardial damage and organ dysfunction.Prognosis in patients with myocarditis depends on the clinical presentation,which ranges from an asymptomatic disease course to the concomitant development of cardiac arrhythmias,heart failure,cardiogenic shock and even the occurrence of death in extreme cases[1]. | Alex Tsz Lai Nganh Sharen Lee Tong LIU Mark Tam Ka Hou Christien Li Michelle Vangi Wong Michael Huen Sum Lam Gary Tse Ishan Lakhani | 2019 | Journal of Geriatric Cardiology2019，16，1： | 2 |
| 3 | Impact of gut microbiome in the development and treatment of pancreatic cancer:Newer insights显示文摘The gut microbiome plays an important role in the variation of pharmacologic response.This aspect is especially important in the era of precision medicine,where understanding how and to what extent the gut microbiome interacts with drugs and their actions will be key to individualizing therapy.The impact of the composition of the gut microbiome on the efficacy of newer cancer therapies such as immune checkpoint inhibitors and chimeric antigen receptor T-cell treatment has become an active area of research.Pancreatic adenocarcinoma(PAC)has a poor prognosis even in those with potentially resectable disease,and treatment options are very limited.Newer studies have concluded that there is a synergistic effect for immunotherapy in combination with cytotoxic drugs,in the treatment of PAC.A variety of commensal microbiota can affect the efficacy of conventional chemotherapy and immunotherapy by modulating the tumor microenvironment in the treatment of PAC.This review will provide newer insights on the impact that alterations made in the gut microbial system have in the development and treatment of PAC. | Ayrton I Bangolo Chinmay Trivedi Ishan Jani Silvanna Pender Hirra Khalid Budoor Alqinai Alina Intisar Karamvir Randhawa Joseph Moore Nicoleta De Deugd Shaji Faisal SuchithBoodgere Suresh Parva Gopani Vignesh K Nagesh Tracy Proverbs-Singh Simcha Weissman | 2023 | World Journal of Gastroenterology2023，29，25： | 2 |
| 4 | Does black hole spin play a key role in the FSRQ/BL Lac dichotomy?显示文摘Blazars are characterized by large intensity and spectral variations across the electromagnetic spectrum It is believed that jets emerging from them are almost aligned with the line-of-sight. The majority of identified extragalactic sources in γ-ray catalogs of EGRET and Fermi are blazars. Observationally,blazars can be divided into two classes: flat spectrum radio quasars(FSRQs) and BL Lacs. BL Lacs usually exhibit lower γ-ray luminosity and harder power law spectra at γ-ray energies than FSRQs. We attempt to explain the high energy properties of FSRQs and BL Lacs from Fermi γ-ray space telescope observations. It was argued previously that the difference in accretion rates is mainly responsible for the large mismatch in observed luminosity in γ-ray. However, when intrinsic luminosities are derived by correcting for beaming effects, this difference in γ-ray luminosity between the two classes is significantly reduced. In order to explain this difference in intrinsic luminosities, we propose that spin plays an important role in the luminosity distribution dichotomy of BL Lacs and FSRQs. As the outflow power of a blazar increases with increasing spin of a central black hole, we suggest that the spin plays a crucial role in making BL Lac sources low luminous and slow rotators compared to FSRQ sources. | Debbijoy Bhattacharya Parameswaran Sreekumar Banibrata Mukhopadhyay Ishan Tomar | 2016 | Research in Astronomy and Astrophysics2016，16，4： | 2 |
| 5 | Heparin-protein interactions显示文摘 | Ishan C Robert JL | 2002 | Angew Chem Int Ed2002，41，： | 1 |
| 6 | What's new: finding signifi2 cant differences in network data streams 显示文摘 | CORMODE G MUTHUKR ISHAN S | 2004 | ACM INFOCOM2004，33，1： | 1 |
| 7 | Teehno-economie Evaluation of Concentrating Solar Power Generation in India 显示文摘 | Ishan Purohit Pallav Purohit | 2010 | Energy Policy2010，38，： | 1 |
| 8 | Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system显示文摘 | SHILADITYA S DAVID E ISHAN C | 2005 | Nature2005，436，7050： | 1 |
| 9 | Characterization and Selection of Phosphorus Deficiency Tolerant Rice Genotypes in Sri Lanka显示文摘Phosphorus(P) deficiency in soil is a major constrain for rice production. An important set of rice genotypes(landraces, old improved and new improved varieties) were screened for P deficiency tolerance in two major cropping seasons of Sri Lanka, in 2012. The Ultisol soil, which was collected from a plot cultivated with rice without fertilizer application for past 40 years(P_0) at the Rice Research and Development Institute(RRDI), Bathalagoda, Sri Lanka, was used as the potting medium for greenhouse trials. Two field trials were conducted in the same plots at RRDI. Both P_0 and P_(30)(30 mg/kg P_2O_5) conditions were used in the two greenhouse trials. At the early vegetative(three weeks after transplanting), late vegetative(six weeks after transplanting) and flowering stages, plant height and number of tillers per plant were recorded. At the flowering stage, shoots were harvested and shoot dry weight, shoot P concentration, shoot P uptake and P utilization efficiency were measured. All data were statistically analyzed using analysis of variance, regression and cluster procedures. The measured parameters were significantly different between P_0 and P_(30) conditions(P < 0.05). Higher shoot dry weight was reported by the rice genotypes H4 and Marss under P_0 conditions. The regression analysis between shoot dry weight and P utilization efficiency revealed that the studied rice genotypes could be categorized to three P deficiency tolerance classes. A total of 13 genotypes could be considered as highly tolerant and 4 genotypes as sensitive for P deficiency. These results could be used to select parental genotypes for breeding and genetic studies and also to select interesting varieties or landraces for organic rice production. | Y. C. ALUWIHARE M. ISHAN M. D. M. CHAMIKARA C. K. WEEBADDE D. N. SIRISENA W. L. G. SAMARASINGHE S. D. S. S. SOORIYAPATHIRANA | 2016 | Rice science2016，23，4： | 1 |
| 10 | Gas hydrate deposition on a cold surface in water-saturated gas systems显示文摘 | RAO Ishan KOH Carolyn A SLOAN E Dendy | 2013 | Industrial&Engineering Chemistry Research2013，52，18： | 1 |
| 11 | Heparin-protein interactions 显示文摘 | Ishan C Robert JL | 2002 | Angew Ehem Int Ed2002，41，： | 1 |
| 12 | Techno-economic evaluation of concentrating solar power generation in India显示文摘 | Ishan Purohit Pallav Purohit | 2010 | Energy Policy2010，，6： | 1 |
| 13 | Multiphase flow modeling of gas hydrates with a simple hydrodynamic slug flow model显示文摘 | LUIS E Z ISHAN R ZACHARY A | 2013 | Chemical Engineering Science2013，99，8： | 1 |
| 14 | Rotenone-induced apoptosis and role of calcium: a study on Neuro-2a cells显示文摘 | Supriya Swarnkar Poonam Goswami Pradeep Kamat Sonam Gupta Ishan Patro Sarika Singh Chandishwar Nath | 2012 | Archives of Toxicology2012，，： | 1 |
| 15 | Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system显示文摘 | Shiladitya Sengupta David Eavarone Ishan Capila | 2005 | Nature2005，436，： | 1 |
| 16 | Temporal targeting of tumour cells and neovasculature with a nanoscale deliv- ery system显示文摘 | Shiladitya S David E Ishan C | 2005 | Nature2005，436，7050： | 1 |
| 17 | Culturally tailored intervention for rural African Americans with type 2 diabetes显示文摘 | Sharon WU Ishan CW Randy J | 2008 | Diabetes Edue2008，34，5： | 1 |
| 18 | Is pulse pressure useful in predicting risk for coronary heart disease? The Framinghan Heart Study 显示文摘 | Frank lin S S Ishan S A Wong S D | 1999 | Circulation1999，100，： | 1 |
| 19 | Biomarket for transforming agriculture to drive Asian economic boom显示文摘 | Ishan Chaturvedi | 2009 | Journal of US-China Public Administration2009，6，1： | 0 |
| 20 | Unusual presentation of extramedullary blast crisis in chronic myeloid leukemia:A case report显示文摘BACKGROUND Extramedullary blast crisis in chronic myeloid leukemia(CML)is an uncommon occurrence of leukemic blast infiltration in regions other than the bone marrow.Malignant infiltration of the serosal membranes should be considered in cases where CML presents with ascites or pleural effusion.CASE SUMMARY A 23-year-old female with CML presented with progressively worsening ascites and pleural effusion despite first-line tyrosine kinase inhibitor treatment.Her blood work indicated leukocytosis with myelocyte bulge and 2%blasts.Analysis of the patient’s bone marrow confirmed the chronic phase of CML.Abdominal ultrasound revealed hepatosplenomegaly with ascites.The fluid investigation of both ascites and pleural effusion revealed a predominance of neutrophils with exudate.However,no acid-fast bacilli or growth was observed after culturing.Although hydroxyurea reduced cell counts,there was no observed effect on ascites or pleural effusion.Repeat investigation of the ascitic and pleural fluid revealed a polymorphous myeloid cell population consisting of myelocytes,metamyelocytes,band forms,neutrophils and a few myeloblasts.Extramedullary blast crisis was suspected,and mutation analysis was performed.We switched the patient to dasatinib.The patient’s symptoms were relieved,and ascites and pleural effusion diminished.CONCLUSION Serosal membrane involvement in CML is extremely rare.In this case,the patient responded well to dasatinib treatment. | Rashmi Mishra Sandeep Garg Praveen Bharti Deepak Ranjan Malla Ishan Rohatgi Sachin Gautam | 2023 | World Journal of Hematology2023，10，4： | 0 |
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