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| 1 | High Risk Factors of Pancreatic Carcinoma显示文摘Over the past decades, cancer has become one of the toughest challenges for health professionals. The epidemiologists are increasingly directing their research efforts on various malignant tumor worldwide. Of note, incidence of cancers is on the rise more quickly in developed countries. Indeed, great endeavors have to be made in the control of the life-threatening disease. As we know it, pancreatic cancer(PC) is a malignant disease with the worst prognosis. While little is known about the etiology of the PC and measures to prevent the condition, so far, a number of risk factors have been identified. Genetic factors, pre-malignant lesions, predisposing diseases and exogenous factors have been found to be linked to PC. Genetic susceptibility was observed in 10% of PC cases, including inherited PC syndromes and familial PC. However, in the remaining 90%, their PC might be caused by genetic factors in combination with environmental factors. Nonetheless, the exact mechanism of the two kinds of factors, endogenous and exogenous, working together to cause PC remains poorly understood. The fact that most pancreatic neoplasms are diagnosed at an incurable stage of the disease highlights the need to identify risk factors and to understand their contribution to carcinogenesis. This article reviews the high risk factors contributing to the development of PC, to provide information for clinicians and epidemiologists. | Soriba Naby Camara 殷涛 杨明 李响 龚琼 周静 赵刚 杨智勇 Tajoo Aroun Martin Kuete Sonam Ramdany Alpha Kabinet Camara Aissatou Taran Diallo 冯珍 宁辛 熊炯新 陶京 钦琪 周伟 崔静 黄敏 郭尧 勾善淼 王博 刘涛 Ohoya Etsaka Terence Olivier Tenin Conde Mohamed Cisse Aboubacar Sidiki Magassouba Sneha Ballah Naby Laye Moussa Keita Ibrahima Sory Souare Aboubacar Toure Sadamoudou Traore Abdoulaye Korse Balde Namory Keita Naby Daouda Camara Dusabe Emmanuel 吴河水 王春友 | 2016 | Journal of Huazhong University of Science and Technology(Medical Sciences)2016，36，3： | 3 |
| 2 | Central line-associated bloodstream infection among children with biliary atresia listed for liver transplantation显示文摘BACKGROUND Pre-transplant nutrition is a key driver of outcomes following liver transplantation in children.Patients with biliary atresia(BA) may have difficulty achieving satisfactory weight gain with enteral nutrition alone,and parenteral nutrition(PN) may be indicated.While PN has been shown to improve anthropometric parameters of children with BA listed for liver transplantation,less is known about the risks,particularly infectious,associated with this therapy among this specific group of patients.AIM To describe the incidence,microbiology,and risk factors of central line-associated bloodstream infection(CLABSI) among children with BA listed for liver transplantation.METHODS Retrospective review of children aged ≤ 2-years of age with BA who were listed for primary liver transplantation at Texas Children's Hospital from 2008 through2015(n = 96).Patients with a central line for administration of PN(n = 63) were identified and details of each CLABSI event were abstracted.We compared the group of patients who experienced CLABSI to the group who did not,to determine whether demographic,clinical,or laboratory factors correlated with development of CLABSI.RESULTS Nineteen of 63 patients(30%,95%CI:19,43) experienced 29 episodes of CLABSI during 4800 line days(6.04 CLABSI per 1000 line days).CLABSI was predominantly associated with Gram-negative organisms(14/29 episodes,48%)including Klebsiella spp.,Enterobacter spp.,and Escherichia coli.The sole polymicrobial infection grew Enterobacter cloacae and Klebsiella pneumoniae.Grampositive organisms(all Staphylococcus spp.) and fungus(all Candida spp.)comprised 9/29(31%) and 6/29(21%) episodes,respectively.No demographic,clinical,or laboratory factors were significantly associated with an increased risk for the first CLABSI event in Cox proportional hazards regression analysis CONCLUSION There is substantial risk for CLABSI among children with BA listed for liver transplantation.No clinical,demographic,or laboratory factor we tested emerged as an independent predictor of CLABSI.While our data did not show an impact of CLABSI on the short-term clinical outcome,it would seem prudent to implement CLABSI reduction strategies in this population to the extent that each CLABSI event represents potentially preventable hospitalization,unnecessary healthcare dollar expenditures,and may exact an opportunity cost,in terms of missed allograft offers. | Nicole D Triggs Stacey Beer Sonam Mokha Kat Hosek Danielle Guffey Charles G Minard Flor M Munoz Ryan W Himes | 2019 | World Journal of Hepatology2019，11，2： | 2 |
| 3 | Etiology, Pathology, Management and Prognosis of Chronic Pancreatitis in Chinese Population: A Retrospective Study显示文摘The purpose of this study was to investigate the etiology, pathological characteristics, management and prognosis of chronic pancreatitis in the Chinese population. The clinical data of 142 patients with chronic pancreatitis were retrospectively studied. All patients were of Chinese nationality and hospitalized from January 2008 to December 2011. Their ages ranged from 14 to 76 years, with a mean of 43 years. Of 142 patients, there were 72 cases of obstructive chronic pancreatitis(50.70%), 19 cases of alcoholic chronic pancreatitis(13.38%), 14 cases of autoimmune pancreatitis(9.86%) and 37 cases of undetermined etiology(26.06%). Pathologically, the average inflammatory mass diameter was 3.8±3.3 cm, biliary obstruction occurred in 36 cases, gall stones in 70 cases, calcification in 88 cases, ductal dilatation in 61 cases, side branch dilatation in 32 cases, ductal irregularity in 10 cases, lymphocytic inflammation in 23 cases, obliterative phlebitis in 14 cases, extra pancreatic lesion in 19 cases and fibrosis in 142 cases. Location of pancreatic lesion in the region of head(n=97), neck(n=16), body(n=12), tail(n=15) and whole pancreas(n=2) influenced the choice of surgical procedures. Ninety-four patients(66.20%) received surgical treatment and 33.80% received other treatments. After operation, 80.85% of 94 patients experienced decreased pain, and 8.51% of 94 showed recovery of endocrine function but with a complication rate of 12.77%. All the operations were performed successfully. According to the pain scale of European Organization for Research and Treatment of Cancer(QLQ-C30) a decrease from 76±22 to 14±18 was observed. Etiology, pathological characteristics, management and prognosis of chronic pancreatitis in the Chinese population vary from others. | Soriba Naby Camara Sonam Ramdany 赵刚 勾善淼 熊炯炘 杨智勇 殷涛 杨明 Oumar Taibata Balde Ahmed Boubacar Barry Seid.Adji 李想 金岩 吴河水 王春友 | 2015 | Journal of Huazhong University of Science and Technology(Medical Sciences)2015，35，3： | 2 |
| 4 | Simultaneous voltammetric determination of hypoxanthine xanthine and uric acid 显示文摘 | Goyal R N Mittal Alok Sharma Sonam | 1994 | Electroanalysis1994，6，7： | 1 |
| 5 | Clinical and magnetic resonance imaging findings in patients with Leigh syndrome and SURF1 mutations显示文摘 | Kothari Sonam Nahid Akthar Khan Parayil Sankaran Bindu Arun B. Taly N. Gayathri M.M. Srinivas Bharath C. Govindaraju H.R. Arvinda Madhu Nagappa Sanjib Sinha K. Thangaraj | 2013 | Brain and Development2013，，： | 1 |
| 6 | Lab Based Contrast Limited Adaptive Histogram Equalization for Underwater Images 显示文摘 | Sonam B | 2015 | International Journal of Computer Application2015，5，4： | 1 |
| 7 | Household perspectives on school attendance in rural Tibet, Gerard Postiglione 显示文摘 | BEN J SONAM G | 2006 | Education review2006，58，3： | 1 |
| 8 | Discovering endangered Tibetic varieties in the easternmost Tibetosphere:A case study on Dartsendo Tibetan显示文摘 | Hiroyuki Suzuki Wangmo Sonam | 2015 | Linguistics of the Tibeto-Burman Area2015，，2： | 1 |
| 9 | Access Control Based Data Security in Cloud Computing显示文摘 | Sonam Chugh Sateesh Kumar Peddoju | | 0，，： | 1 |
| 10 | Changes in megakaryocytes in case of thrombocytopenia:bone marrow aspiration and biopsy analysis显示文摘 | Tejinder SB Sonam S Mridu M | 2013 | J Clin Diagn Res2013，7，3： | 1 |
| 11 | Cell Signaling Pathways Involved During Invasion and Syncytialization of Trophoblast Cells显示文摘 | Satish Kumar Gupta Sudha Saryu Malhotra Ankita Malik Sonam Verma Piyush Chaudhary | 2016 | Am J Reprod Immunol2016，，： | 1 |
| 12 | Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer显示文摘 | J. Chad Brenner Bushra Ateeq Yong Li Anastasia K. Yocum Qi Cao Irfan A. Asangani Sonam Patel Xiaoju Wang Hallie Liang Jindan Yu Nallasivam Palanisamy Javed Siddiqui Wei Yan Xuhong Cao Rohit Mehra Aaron Sabolch Venkatesha Basrur Robert J. Lonigro Jun Yang | 2011 | Cancer Cell2011，，5： | 1 |
| 13 | Rotenone-induced apoptosis and role of calcium: a study on Neuro-2a cells显示文摘 | Supriya Swarnkar Poonam Goswami Pradeep Kamat Sonam Gupta Ishan Patro Sarika Singh Chandishwar Nath | 2012 | Archives of Toxicology2012，，： | 1 |
| 14 | Manual small incision cataract surgery for subluxated cataract with lens coloboma显示文摘 | Ruchi Goel Saurabh Kamal Bhawna Khurana Sushil Kumar K.P.S. Malik Sonam Angmo Bodh Malvika Singh | 2011 | Contact Lens and Anterior Eye2011，，2： | 1 |
| 15 | Development of the pneumatic valve with bimorph type PZT ac-tuator显示文摘 | Yun Sonam Lee Kyungwoo Kim Honghee | 2006 | Materials Chemistry and Physics2006，97，1： | 1 |
| 16 | Is targetingeNOS a key mechanistic insight of cardiovascular defensivepotentials of statins 显示文摘 | Pitchai Balakumar Sonam Kathuria Gaurav Taneja | 2012 | Journal of Molecular and CellularCardiology2012，52，1： | 1 |
| 17 | Wavefront fitting and comparison of camera aberrations using Zernike circle polynomials显示文摘 | Sonam Singh Dinesh Ganotra | 2013 | Optik - International Journal for Light and Electron Optics2013，，16： | 1 |
| 18 | Bilateral hypertrophic olivary nucleus degeneration on magnetic resonance imaging in children with Leigh and Leigh-like syndrome 显示文摘 | Bindu PS Taly AB Sonam K | 2014 | Br J Radiol2014，87，20： | 1 |
| 19 | Free to be me: a survey study on eustomization with World of Warcraft and City Of Heroes/Villains players 显示文摘 | Selen Turkay Sonam Adinolf | 2010 | Procedia Social and Behavioral Seiences2010，，2： | 1 |
| 20 | Safety and Efficacy of Green Foliage in the Treatment of Fungal Infections and Associated Clinical Conditions显示文摘 | Sandeep Dhankhar Seema Dhankhar Sonam Ruhil Manish Kumar Mrridula Narwal Meenakshi Balhara A.K. Chhillar | 2013 | Current Drug Safety2013，，4： | 1 |
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