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| 1 | Conventional digital cameras as a tool for assessing leaf area index and biomass for cereal breeding显示文摘Affordable and easy-to-use methods for assessing biomass and leaf area index(LAI) would be of interest in most breeding programs. Here, we describe the evaluation of a protocol for photographic sampling and image analysis aimed at providing low-labor yet robust indicators of biomass and LAI. In this trial, two genotypes of triticale, two of bread wheat, and four of tritordeum were studied. At six dates during the growing cycle, biomass and LAI were measured destructively, and digital photography was taken on the same dates. Several vegetation indices were calculated from each image. The results showed that repeatable and consistent values of the indices were obtained in consecutive photographic samplings on the same plots. The photographic indices were highly correlated with the destructive measurements, though the magnitude of the correlation was lower after anthesis. This work shows that photographic assess-ment of biomass and LAI can be fast, affordable, have good repeatability, and can be used under bright and overcast skies. A practical vegetation index derived from pictures is the fraction of green pixels over the total pixels of the image, and as it shows good correlations with all biomass variables, is the most robust to lighting conditions and has easy interpretation. | Jaume Casadesús Dolors Villegas | 2014 | Journal of Integrative Plant Biology2014，56，1： | 7 |
| 2 | Local recurrence of a parosteal osteosarcoma 21 years after incomplete resection显示文摘Parosteal osteosarcoma (POS) is the most common form of surface osteosarcoma. Its symptoms are insidious and its duration prior to diagnosis is considerably longer than that of other types of osteosarcoma. We report a case of POS with a growing mass but no evidence of metastasis. This tumor, which was diagnosed as calcified hematoma with benign characteristics, was incompletely resected in our hospital 21 years before the diagnosis of recurrence. The patient underwent a wide en bloc resection in our hospital and was free of symptoms, with no signs of tumor recurrence or metastasis during a 53-month follow-up. | Andrés Combalia Ernesto Muoz-Mahamud Antonio Palacín Jaume Pomés Vicente López | 2011 | Chinese Journal of Cancer2011，30，12： | 5 |
| 3 | Exploratory study on microRNA profiles from plasma-derived extracellular vesicles in Alzheimer’s disease and dementia with Lewy bodies显示文摘Background:Because of the increasing life expectancy in our society,aging-related neurodegenerative disorders are one of the main issues in global health.Most of these diseases are characterized by the deposition of misfolded proteins and a progressive cognitive decline.Among these diseases,Alzheimer’s disease(AD)and dementia with Lewy bodies(DLB)are the most common types of degenerative dementia.Although both show specific features,an important neuropathological and clinical overlap between them hampers their correct diagnosis.In this work,we identified molecular biomarkers aiming to improve the misdiagnosis between both diseases.Methods:Plasma extracellular vesicles(EVs)-from DLB,AD and healthy controls-were isolated using size-exclusion chromatography(SEC)and characterized by flow cytometry,Nanoparticle Tracking Analysis(NTA)and cryo-electron microscopy.Next Generation Sequencing(NGS)and related bibliographic search was performed and a selected group of EV-associated microRNAs(miRNAs)was analysed by qPCR.Results:Results uncovered two miRNAs(hsa-miR-451a and hsa-miR-21-5p)significantly down-regulated in AD samples respect to DLB patients,and a set of four miRNAs(hsa-miR-23a-3p,hsa-miR-126-3p,hsa-let-7i-5p,and hsamiR-151a-3p)significantly decreased in AD respect to controls.The two miRNAs showing decreased expression in AD in comparison to DLB provided area under the curve(AUC)values of 0.9 in ROC curve analysis,thus suggesting their possible use as biomarkers to discriminate between both diseases.Target gene analysis of these miRNAs using prediction online tools showed accumulation of phosphorylation enzymes,presence of proteasome-related proteins and genes involved in cell death among others.Conclusion:Our data suggest that plasma-EV associated miRNAs may reflect a differential profile for a given dementia-related disorder which,once validated in larger cohorts of patients,could help to improve the differential diagnosis of DLB versus AD. | Ana Gámez-Valero Jaume Campdelacreu Dolores Vilas Lourdes Ispierto Ramón Reñé RamiroÁlvarez MPilar Armengol Francesc E.Borràs Katrin Beyer | 2019 | Translational Neurodegeneration2019，8，1： | 4 |
| 4 | Determination of drug,excipients and coating distribution in pharmaceutical tablets using NIR-CI显示文摘The growing interest of the pharmaceutical industry in Near Infrared-Chemical Imaging (NIR-CI) is a result of its high usefulness for quality control analyses of drugs throughout their production process (particularly of its non-destructive nature and expeditious data acquisition).In this work,the concentration and distribution of the major and minor components of pharmaceutical tablets are determined and the spatial distribution from the internal and external sides has been obtained.In addition,the same NIR-CI allowed the coating thickness and its surface distribution to be quantified.Images were processed to extract the target data and calibration models constructed using the Partial Least Squares (PLS) algorithms.The concentrations of Active Pharmaceutical Ingredient (API) and excipients obtained for uncoated cores were essentially identical to the nominal values of the pharmaceutical formulation.But the predictive ability of the calibration models applied to the coated tablets decreased as the coating thickness increased. | Anna Palou Jordi Cruz Marcelo Blanco Jaume Tomàs Joaquín de los Ríos Manel Alcalà | 2012 | Journal of Pharmaceutical Analysis2012，2，2： | 4 |
| 5 | Lanreotide in Metastatic Enteropancreatic Neuroendocrine Tumors显示文摘 | Martyn E. Caplin Marianne Pavel Jaros?aw B. ?wik?a Alexandria T. Phan Markus Raderer Eva Sedlá?ková Guillaume Cadiot Edward M. Wolin Jaume Capdevila Lucy Wall Guido Rindi Alison Langley Séverine Martinez Jo?lle Blumberg Philippe Ruszniewski | 2014 | The New England Journal of Medicine2014，，： | 3 |
| 6 | Accumulation of Pb and Zn in Bidens triplinervia and Senecio sp. spontaneous species from mine spoils in Peru and their potential use in phytoremediation显示文摘 | Jaume Bech Paola Duran Núria Roca Wilfredo Poma Isidoro Sánchez Luis Roca-Pérez Rafael Boluda Juan Barceló Charlotte Poschenrieder | 2012 | Journal of Geochemical Exploration2012，，： | 2 |
| 7 | Relationship of lipid oxidation with subclinical atherosclerosis and 10-year coronary events in general population显示文摘 | Miquel Gómez Joan Vila Roberto Elosua Lluís Molina Jordi Bruguera Joan Sala Rafel Masià Maria Isabel Covas Jaume Marrugat Montserrat Fitó | 2014 | Atherosclerosis2014，，1： | 1 |
| 8 | Skeletal Muscle Apoptosis andWeight loss in Chronic Obstructive Pulmonary Disease显示文摘 | Alvar GN Agusti Jaume S | 2002 | A m JRespir Crit Care Med2002，166，4： | 1 |
| 9 | Analysis of the relative in- crease in photosynthetic 02 up take when photosynthesis in grape- vine leaves is inhibited following low night temperatures and or water stress显示文摘 | Jaume F Murray B Wah S C | 1999 | Plant Physiology1999，121，2： | 1 |
| 10 | A general algorithm for automated scheduling of drip irrigation in tree crops显示文摘 | Jaume Casadesús Mercè Mata Jordi Marsal Joan Girona | 2012 | Computers and Electronics in Agriculture2012，，： | 1 |
| 11 | Molecular cloning and characterization of genes for antibodies generated by orbitaltissue-infiltrating B-cells in Graves' ophthalmopathy显示文摘 | Portolano S Prummel MF | 1994 | J Clin Endocrinol Metab1994，78，： | 1 |
| 12 | On the 16th Hilbert problem for algebraic limit cycles显示文摘 | JAUME L RAFAEL R NATALIA S | 2010 | J Differential Equations2010，248，6： | 1 |
| 13 | Clinical events after transjugular intrahepatic portosystemic shunt: Correlation with hemodynamic findings显示文摘 | Marta Casado Jaume Bosch Juan Carlos García-Pagán Conxita Bru Rafael Ba?ares Juan Carlos Bandi Angels Escorsell José Manuel Rodríguez-Láiz Rosa Gilabert Faust Feu Carlos Schorlemer Antonio Echenagusia Joan Rodés | 1998 | Gastroenterology1998，，6： | 1 |
| 14 | Diabetes-associated dry eye syn- dromein a new humanized transgenic model of type 1 diabetes显示文摘 | Imam S Elagin RB Jaume JC | 2013 | Mol Vis2013，8，19： | 1 |
| 15 | Evolving towards a critical point:a review of accelerating seismic moment/energy release prior to large and great earthquakes显示文摘 | Jaumé S C Sykes L R | 1999 | Pure and Applied Geophysics1999，155，24： | 1 |
| 16 | Anti-severe acute re- spiratory syndrome coronavirus spike antibodies trigger infec- tion of human immune cells via a pH- and cysteine prote- ase-independent FcR pathway显示文摘 | Jaume M Yip M S Cheung C Y | 2011 | J Virol2011，85，10： | 1 |
| 17 | Variability of water use efficiency in grapevines显示文摘 | Magdalena Tomás Hipólito Medrano Jose M. Escalona Sebastià Martorell Alicia Pou Miquel Ribas-Carbó Jaume Flexas | 2013 | Environmental and Experimental Botany2013，，： | 1 |
| 18 | Prediction of Postoperative Pulmonary Complications in a Population-based Surgical Cohort显示文摘 | Jaume Canet Lluís Gallart Carmen Gomar Guillem Paluzie Jordi Vallès Jordi Castillo Sergi Sabaté Valentín Mazo Zahara Briones Joaquín Sanchis | 2010 | Anesthesiology2010，，6： | 1 |
| 19 | Responses of leaf night transpiration to drought stress in Vitis vinifera L.显示文摘 | José Mariano Escalona Sigfredo Fuentes Magdalena Tomás Sebastià Martorell Jaume Flexas Hipólito Medrano | 2013 | Agricultural Water Management2013，，： | 1 |
| 20 | Average daily light interception determines leaf water use efficiency among different canopy locations in grapevine显示文摘 | Hipólito Medrano Alicia Pou Magdalena Tomás Sebastià Martorell Javier Gulias Jaume Flexas José M. Escalona | 2012 | Agricultural Water Management2012，，： | 1 |
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