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| 1 | Investigation and Analysis of Rabies Viral Infection and Distribution in China in 2005-2012显示文摘Dear Editor, We report the results of a preliminary investigation of data collected between 2005 and 2012. A National Human Rabies Surveillance program was initiated in high rabies incidence regions in 2005, and subsequently carried out nationally to monitor rabies situation. Our work presents a summary of epidemiological and etiologic rabies surveillance data collected since the implementation of the program. | Wentao Jiao Hao Li Xiaoyan Tao Miao Song Xinxin Shen Zhenyang Guo Yunjiao Zhao Qing Tang Guodong Liang | 2013 | Virologica Sinica2013,28,3: | 6 |
| 2 | Hyperthermia based individual in situ recombinant vaccine enhances lymph nodes drainage for de novo antitumor immunity显示文摘The continuing challenges that limit effectiveness of tumor therapeutic vaccines were high heterogeneity of tumor immunogenicity, low bioactivity of antigens, as well as insufficient lymph nodes(LNs) drainage of antigens and adjuvants. Transportation of in situ neoantigens and adjuvants to LNs may be an effective approach to solve the abovementioned problems. Therefore, an FA-TSL/AuNCs/SV nanoplatform was constructed by integrating simvastatin(SV) adjuvant loaded Au nanocages(AuNCs)as cores(AuNCs/SV) and folic acid modified thermal-sensitive liposomes(FA-TSL) as shells to enhance de novo antitumor immunity. After accumulation in tumor guided by FA, AuNCs mediated photothermal therapy(PTT) induced the release of tumor-derived protein antigens(TDPAs) and the shedding of FATSL. Exposed AuNCs/SV soon captured TDPAs to form in situ recombinant vaccine(AuNCs/SV/TDPAs). Subsequently, AuNCs/SV/TDPAs could efficiently transport to draining LNs owing to the hyperthermia induced vasodilation effect and small particle size, achieving co-delivery of antigens and adjuvant for initiation of specific T cell response. In melanoma bearing mice, FA-TSL/AuNCs/SV and laser irradiation effectively ablated primary tumor, against metastatic tumors and induced immunological memory. This approach served a hyperthermia enhanced platform drainage to enable robust personalized cancer vaccination. | Cuixia Zheng Xinxin Liu Yueyue Kong Lei Zhang Qingling Song Hongjuan Zhao Lu Han Jiannan Jiao Qianhua Feng Lei Wang | 2022 | Acta Pharmaceutica Sinica B2022,12,8: | 2 |
| 3 | Revealing the surface atomic arrangement of noble metal alkane dehydrogenation catalysts by a stepwise reduction-oxidation approach显示文摘Surface characterization of metal nanoparticles is a critical need in nanocatalysis for in-depth understanding of the structure-function relationships.The surface structure of nanoparticles is often different from the subsurface,and it is challenging to separately characterize the surface and the subsurface.In this work,theoretical calculations and extended X-ray absorption fine structure(EXAFS)analysis illustrate that the surface atoms of noble metals(Pt and Pd)are oxidized in the air,while the subsurface atoms are not easily oxidized.Taking advantage of the oxidation properties,we suggest a stepwise reduction-oxidation approach to determine the surface atomic arrangement of noble metal nanoparticles,and confirm the rationality of this approach by identifying the surface structure of typical 2-3 nm Pt and Pd nanoparticles.The reduction-oxidation approach is applied to characterize the surface structure of model Pd-Sb bimetallic catalyst,which illustrates that the surface Pd is well isolated by Sb atoms with short bond distance at 2.70Å,while there are still Pd-Pd bonds in the subsurface.Density functional theory(DFT)calculations and Pd L edge X-ray absorption near edge structure(XANES)indicate that the isolation of surface Pd significantly decreases the adsorption energies of Pd-hydrocarbon,which leads to the high propylene selectivity and turnover frequency Pd-Sb bimetallic catalyst for propane dehydrogenation. | Chenliang Ye Mao Peng Tingting Cui Xinxin Tang Dingsheng Wang Miaolun Jiao Jeffrey T.Miller Yadong Li | 2023 | Nano Research2023,16,4: | 0 |
| 4 | Photocatalytic Degradation of 4-Chlorophenol by Gd-Doped β-Bi2O3 Under Visible Light Irradiation显示文摘Chlorophenols are known as persistent organic pollutants.Therefore,research on the removal of chlorophenols has attracted widespread attention.Hereto,the photocatalytic degradation of 4-chlorophenol by Gd-doped β-Bi2O3 under visible light irradiation was studied.The results showed that Gd-doped β-Bi2O3 materials are efficient catalysts for the photocatalytic degradation of chlorophenols,and 2%(atomic traction)Gd-doped β-Bi2O3 exhibits the highest photocatalytic activity for 4-chlorophenol degradation,because doping an appropriate amount of Gd^3+ions can effectively reduce the recombination rate of the photogenerated e^-/h^+pairs and then enhance the photocatalytic performance.When the reaction was carried out at 25 ℃ for 6 h using the 2% Gd-doped/β-Bi2O3 micro/nano materials of 200 mg and at air flow rate of 40 mL/min,the degradation rate of 4-chlorophenol reached 92.3%.Additionally based on the analysis of the products,it was speculated that the dominant photocatalytic degradation mechanism of 4-chlorophenol by Gd-doped β-Bi2O3 under visible light irradiation is an oxidative process involving an attack by the hydroxyl radical. | LIN Shijing DU Wutong TONG Laga JI Tao JIAO Xinxin | 2019 | Chemical Research in Chinese Universities2019,35,1: | 0 |
| 5 | Hypergraph-Based Data Reduced Scheduling Policy for Data-Intensive Workflow in Clouds显示文摘Data-intensive computing is expected to be the next-generation IT computing paradigm. Data-intensive workflows in clouds are becoming more and more popular. How to schedule data-intensive workflow efficiently has become the key issue. In this paper, first, we build a directed hypergraph model for data-intensive workflow, since Hypergraphs can more accurately model communication volume and better represent asymmetric problems, and the cut metric of hypergraphs is well suited for minimizing the total volume of communication.Second, we propose a concept data supportive ability to help the presentation of data-intensive workflow application and provide the merge operation details considering the data supportive ability. Third, we present an optimized hypergraph multi-level partitioning algorithm. Finally we bring a data reduced scheduling policy HEFT-P for data-intensive workflow. Through simulation,we compare HEFT-P with three typical workflow scheduling policies.The results indicate that HEFT-P could obtain reduced data scheduling and reduce the makespan of executing data-intensive | Zhigang Hu Jia Li Meiguang Zheng Xinxin Zhang Hui Kang Yong Tao Jiao Yang | 2017 | 国际计算机前沿大会会议论文集2017,,2: | 0 |
| 6 | Long-term light grazing does not change soil organic carbon stability and stock in biocrust layer in the hilly regions of drylands显示文摘Livestock grazing is the most extensive land use in global drylands and one of the most extensive stressors of biological soil crusts(biocrusts).Despite widespread concern about the importance of biocrusts for global carbon(C)cycling,little is known about whether and how long-term grazing alters soil organic carbon(SOC)stability and stock in the biocrust layer.To assess the responses of SOC stability and stock in the biocrust layer to grazing,from June to September 2020,we carried out a large scale field survey in the restored grasslands under long-term grazing with different grazing intensities(represented by the number of goat dung per square meter)and in the grasslands strictly excluded from grazing in four regions(Dingbian County,Shenmu City,Guyuan City and Ansai District)along precipitation gradient in the hilly Loess Plateau,China.In total,51 representative grassland sites were identified as the study sampling sites in this study,including 11 sites in Guyuan City,16 sites in Dingbian County,15 sites in Shenmu City and 9 sites in Ansai District.Combined with extensive laboratory analysis and statistical analysis,at each sampling site,we obtained data on biocrust attributes(cover,community structure,biomass and thickness),soil physical-chemical properties(soil porosity and soil carbon-to-nitrogen ratio(C/N ratio)),and environmental factors(mean annual precipitation,mean annual temperature,altitude,plant cover,litter cover,soil particle-size distribution(the ratio of soil clay and silt content to sand content)),SOC stability index(SI)and SOC stock(SOCS)in the biocrust layer,to conduct this study.Our results revealed that grazing did not change total biocrust cover but markedly altered biocrust community structure by reducing plant cover,with a considerable increase in the relative cover of cyanobacteria(23.1%)while a decrease in the relative cover of mosses(42.2%).Soil porosity and soil C/N ratio in the biocrust layer under grazing decreased significantly by 4.1%–7.2%and 7.2%–13.3%,respectively,compared with those under grazing exclusion.The shifted biocrust community structure ultimately resulted in an average reduction of 15.5%in SOCS in the biocrust layer under grazing.However,compared with higher grazing(intensity of more than 10.00 goat dung/m2),light grazing(intensity of 0.00–10.00 goat dung/m2 or approximately 1.20–2.60 goat/(hm2•a))had no adverse effect on SOCS.SOC stability in the biocrust layer remained unchanged under long-term grazing due to the offset between the positive effect of the decreased soil porosity and the negative effect of the decreased soil C/N ratio on the SOC resistance to decomposition.Mean annual precipitation and soil particle-size distribution also regulated SOC stability indirectly by influencing soil porosity through plant cover and biocrust community structure.These findings suggest that proper grazing might not increase the CO_(2) release potential or adversely affect SOCS in the biocrust layer.This research provides some guidance for proper grazing management in the sustainable utilization of grassland resources and C sequestration in biocrusts in the hilly regions of drylands. | MA Xinxin ZHAO Yunge YANG Kai MING Jiao QIAO Yu XU Mingxiang PAN Xinghui | 2023 | Journal of Arid Land2023,15,8: | 0 |