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| 1 | Down-scaled regional ocean modeling system (ROMS) for high-resolution coastal hydrodynamics in Korea显示文摘A down-scaled operational oceanographic system is developed for the coastal waters of Korea using a regional ocean modeling system(ROMS).The operational oceanographic modeling system consists of atmospheric and hydrodynamic models.The hydrodynamic model,ROMS,is coupled with wave,sediment transport,and water quality modules.The system forecasts the predicted results twice a day on a 72 h basis,including sea surface elevation,currents,temperature,salinity,storm surge height,and wave information for the coastal waters of Korea.The predicted results are exported to the web-GIS-based coastal information system for real-time dissemination to the public and validation with real-time monitoring data using visualization technologies.The ROMS is two-way coupled with a simulating waves nearshore model,SWAN,for the hydrodynamics and waves,nested with the meteorological model,WRF,for the atmospheric surface forcing,and externally nested with the eutrophication model,CE-QUAL-ICM,for the water quality.The operational model,ROMS,was calibrated with the tidal surface observed with a tide-gage and verified with current data observed by bottom-mounted ADCP or AWAC near the coastal waters of Korea.To validate the predicted results,we used real-time monitoring data derived from remote buoy system,HF-radar,and geostationary ocean color imager(GOCI).This down-scaled operational coastal forecasting system will be used as a part of the Korea operational oceanographic system(KOOS) with other operational oceanographic systems. | LIM Hak-Soo KIM Chang S PARK Kwang-Soon SHIM Jae Seol CHUN Insik | 2013 | Acta Oceanologica Sinica2013，32，9： | 4 |
| 2 | Features of extrahepatic metastasis after radiofrequency ablation for hepatocellular carcinoma显示文摘BACKGROUND Extrahepatic metastasis(EHM)of hepatocellular carcinoma(HCC)is associated with poor outcomes.However,the clinical features and risk factors of EHM of HCC after radiofrequency ablation(RFA)remain unclear.AIM To elucidate the characteristics and risk factors of EHM after RFA for HCC.METHODS From January 2008 to December 2017,we retrospectively enrolled 661 patients who underwent RFA as first-line treatment for HCC at 2 tertiary hospitals.The inclusion criteria were age≥18 years,a diagnosis of HCC,and treatment-naivety.Abdominal computed tomography(CT)or magnetic resonance imaging(MRI)and alpha-fetoprotein measurements were routinely performed at 1 mo after RFA and followed-up at intervals of 3-6 mo.Univariate analyses were performed using the chi-squared test or Student’s t-test,and univariate and multivariate analyses were performed via logistic regression,as appropriate.RESULTS EHM was diagnosed in 44 patients(6.7%)during a median follow-up period of 1204 days.The 10-year cumulative rate of HCC recurrence and EHM was 92.7%and 33.7%,respectively.Initial recurrence was most often intrahepatic,and the rate of extrahepatic recurrence at initial recurrence was only 1.2%.The median time to the diagnosis of EHM was 2.68 years,and 68.2%of patients developed EHM within 2 years of the first recurrence,regardless of recurrence-free survival and 75.0%of patients developed EHM within 5 years after first recurrence.EHM was mostly diagnosed via abdominal CT/MRI in 33(75.0%)and 38 of 44 patients(86.4%)with EHM had either positive abdominal CT scan results or serum AFP level elevation.In multivariate analysis,recurrence-free survival<2 years,ablation zone/tumor size<2,and alpha-fetoprotein level>400 IU/mL were associated with a high EHM risk.CONCLUSION EHM occurs following multiple intrahepatic recurrences after RFA and combined contrast-enhanced abdominal CT and serum AFP were useful for surveillance.Patients especially with high-risk factors require close follow-up for EHM. | Jae H Yoon Young J Goo Chae-Jun Lim Sung K Choi Sung B Cho Sang S Shin Chung H Jun | 2020 | World Journal of Gastroenterology2020，26，32： | 3 |
| 3 | Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial显示文摘 | Charles S Fuchs Jiri Tomasek Cho Jae Yong Filip Dumitru Rodolfo Passalacqua Chanchal Goswami Howard Safran Lucas Vieira dos Santos Giuseppe Aprile David R Ferry Bohuslav Melichar Mustapha Tehfe Eldar Topuzov John Raymond Zalcberg Ian Chau William Campbell | 2014 | The Lancet2014，，9911： | 3 |
| 4 | Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial显示文摘 | Charles S Fuchs Jiri Tomasek Cho Jae Yong Filip Dumitru Rodolfo Passalacqua Chanchal Goswami Howard Safran Lucas Vieira dos Santos Giuseppe Aprile David R Ferry Bohuslav Melichar Mustapha Tehfe Eldar Topuzov John Raymond Zalcberg Ian Chau William Campbell | 2014 | 2014 (9911)2014，，9911： | 2 |
| 5 | 男性C反应蛋白、纤维蛋白原和心肺适应性与高血压发生风险的相关性显示文摘在正常血压和高血压高危人群中,较高的心肺适应性(cardiorespiratory fitness)可预防高血压[1-2]。但高心肺适应性能否降低炎症水平升高的受试者发生高血压的风险,尚不清楚。本研究旨在探讨男性中,独立于肥胖,炎症与高血压发生的相关性;心肺适应性、炎症与高血压发生的联合相关性。研究者假设炎症与高血压发生相关,但高心肺适应性可降低这种相关性。 | Jae SY Kurl S Laukkanen JA Lee CD Choi YH Fernhall B Franklin BA | 2015 | 中华高血压杂志2015，23，9： | 2 |
| 6 | International experts consensus guidelines on robotic liver resection in 2023显示文摘The robotic liver resection(RLR)has been increasingly applied in recent years and its benefits shown in some aspects owing to the technical advancement of robotic surgical system,however,controversies still exist.Based on the foundation of the previous consensus statement,this new consensus document aimed to update clinical recommendations and provide guidance to improve the outcomes of RLR clinical practice.The guideline steering group and guideline expert group were formed by 29 international experts of liver surgery and evidence-based medicine(EBM).Relevant literature was reviewed and analyzed by the evidence evaluation group.According to the WHO Handbook for Guideline Development,the Guidance Principles of Development and Amendment of the Guidelines for Clinical Diagnosis and Treatment in China 2022,a total of 14 recommendations were generated.Among them were 8 recommendations formulated by the GRADE method,and the remaining 6 recommendations were formulated based on literature review and experts’opinion due to insufficient EBM results.This international experts consensus guideline offered guidance for the safe and effective clinical practice and the research direction of RLR in future. | Rong Liu Mohammed Abu Hilal Go Wakabayashi Ho-Seong Han Chinnusamy Palanivelu Ugo Boggi Thilo Hackert Hong-Jin Kim Xiao-Ying Wang Ming-Gen Hu Gi Hong Choi Fabrizio Panaro Jin He Mikhail Efanov Xiao-Yu Yin Roland S Croner Yu-Man Fong Ji-Ye Zhu Zheng Wu Chuan-Dong Sun Jae Hoon Lee Marco V Marino Iyer Shridhar Ganpati Peng Zhu Zi-Zheng Wang Ke-Hu Yang Jia Fan Xiao-Ping Chen Wan Yee Lau | 2023 | World Journal of Gastroenterology2023，29，32： | 2 |
| 7 | Overexpression of Arabidopsis phytochelatin synthase paradoxically leads to hypersensitivity to cadmium stress显示文摘 | Sangman Lee Jae s Moon Tae-Seok Ko | 2003 | Plant Physiology2003，131，： | 1 |
| 8 | Critical velocity and burning rate in pool fire during longitudinal ventilation显示文摘 | JAE S R HING S R DONG H K | 2007 | Tunnelling and Underground Space Technology2007，，22： | 1 |
| 9 | Transduction of human catalase mediated by an HIV-1 tat protein basic domain and arginine-rich peptides into mammalian cells 显示文摘 | LI H J JAE H B WON S E | 2001 | Free Radical Biology & Medicine2001，31，11： | 1 |
| 10 | Understanding Information Technology Acceptance by Individual Professionals: Toward an Integrative View显示文摘 | Mun Y Yi Joyce D Jackson Jae S Park | 2006 | Information and Management2006，43，3： | 1 |
| 11 | A study on die wear model considering thermal softening ( Ⅱ ): Application of the suggested wear model显示文摘 | Kang J H Park I W Jae J S | 1999 | Journal of Materials Processing Technology1999，94，23： | 1 |
| 12 | The Performance of Remote Display Mechanisms for Thin-Client Computing显示文摘 | S Jae Yong Jason Nieh Matt Selsky | 2002 | In:Proceddings of the 2002 USENIX Annual Technical Conference2002，，6： | 1 |
| 13 | Targeted delivery of low moleculardrugs using chitosan and its derivatives显示文摘 | Jae H P Gurusamy S Kwangmeyung K | 2010 | Advanced Drug Delivery Revie-ws2010，62，： | 1 |
| 14 | The imp-ortance of phase in signals显示文摘 | Ian V Oppenheim Jae S Lira | 1981 | Proceedings of the IEEE1981，69，5： | 1 |
| 15 | Atomic scale investigation on the distribution of boron in medium carbon steels by atom probe tomography and EELS显示文摘 | JAE B S GIL H G NAMS L | 2010 | Ultramicroscopy2010，110，7： | 1 |
| 16 | Laser clad Ni-base alloy added nano- and micron-size CeO2 composites显示文摘 | Zhang S H Li M X Tong Yul Cho Jae Hong Yoon Chan Gyu Lee and He Y Z | 2008 | Optics & Laser Technology2008，40，5： | 1 |
| 17 | Improved method for efficient production of biodiesel from palm oil显示文摘 | RAHMAN TALUKDER M M MIN BEATRICE K L PUAY SONG O PUAH S CHUAN WU J JAE WON C CHOW Y | 2008 | Energy Fuels2008，22，1： | 1 |
| 18 | Lack of association between vitamin D receptor genotypes and osteoporosis in Korean显示文摘 | Sung K L Young S P Jae M P | 1995 | J Clin Endocrinol Metab1995，80，12： | 1 |
| 19 | A new process for the synthesis of diphenyl carbonate from dimethyl carbonate and phenol over heterogeneous catalysts显示文摘 | Won B K Jae S L | 1999 | Catalyst Letter1999，59，1： | 1 |
| 20 | REGARD:A phase III,randomized,double-blinded trial of ramucirumab and best supportive care(BSC)versus placebo and BSC in the treatment of metastatic gastric or gastroesophageal junction(GEJ)adenocarcinoma following disease progression on first-line platinum-and/or fluoropyrimidine-containing combination therapy显示文摘 | Charles S Fuchs Jiri T Jae Y | 2012 | J Clin Oncol2012，，： | 1 |
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