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您的检索式：作者名="Jalaj Kumar"
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| 1 | Stress triaxiality effect on fracture behavior of IMI-834 titanium alloy: A micromechanics approach 显示文摘 | Jalaj Kumar | 2009 | Materials and Design2009，30，： | 1 |
| 2 | Stress triaxiality effect on fracture behavior of IMI-834 titanium alloy: A micromechanics approach显示文摘 | Jalaj Kumar B. Srivathsa Vikas Kumar | 2008 | Materials and Design2008，，4： | 1 |
| 3 | Cyanobacteria,Lyngbya aestuarii and Aphanothece bullosa as antifungal and antileishmanial drug resources显示文摘Objective:To investigate two cyanobacteria isolated from different origins i.e.Lyngbya aestuarii(L.aestuarii)from brackish water and Aphanothece bullosa(4.bullosa)from fresh water paddy fields for antifungal and antileishmanila activity taking Candida albicans and Leishmania donovain as targets.Methods:Biomass of L.aestuarii and A.bullosa were harvested after 40 and60 d respectively and lyophilized twice in methanol(100%)and redissolved in methanol(5%)for bioassay.Antifungal bioassay was done by agar well diffusion method while antileishmanial,by counting cell numbers and flageller motility observation of promastigotes and amastigotes from L.donovani.fluconazole and 5%methanol were used as control.Results:Both the cyanobacteria were found to be potent source of antifungal activity keeping fluconazole as positive control,however,methanolic crude extract(15 mg/mL)of A.bullosa was found more potent(larger inhibition zone)over that of methanolic crude extract of L.aestuarii,Similarly antileishmanial activity of crude extract(24.0 mg/mL)of A.bullosa was superior over that of methanolic crude extract of L.aestuarii(25.6 mg/mL).Conclusions:Antifungal and antileishmanial drugs are still limited in the market.Screening of microbes possessing antifungal and antileishmanial activity drug is of prime importance.Cyanobacteria are little explored in this context because most of the drugs in human therapy are derived from microorganisms,mainly bacterial,fungal and actinomycetes.Thus in the present study two cyanobacterial strains from different origins showed potent source of antifungal and antileishmanial biomolecules. | Maheep Kumar Manoj Kumar Tripathi Akanksha Srivastava Jalaj Kumar Gour Rakesh Kumar Singh Ragini Tilak Ravi Kumar Asthana | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，6： | 0 |
| 4 | Detection of urinary antigens and their seroreactivity with serum of patients in Leishmania donovani infection显示文摘Objective:To detect leishmanial antigens in pre and post treated urine of visceral leishmaniasis (VL) patients.Methods:Urine and serum sample from three VL patients were collected. Ammonium sulphate precipitation and purification of urine sample was done for proteins isolation.SDS PAGE of proteins was done followed by western blotting,with the patient’s pre and post treatment serum.Results:Eight proteins of molecular weights 17 kDa,25 kDa,28 kDa,42 kDa, 47 kDa,54 kDa,60 kDa and 85 kDa were detected in the urine of VL patients before treatment. After treatment with miltefosine,none of the above proteins was detected in urine samples.The western blot analysis with pre treatment serum confirmed the antigenicity of four urinary proteins of molecular weights 25 kDa,28 kDa,54 kDa and 60 kDa.The seropositivity with 25 kDa and 28 kDa antigens was negative with serum obtained after the completion of treatment.Conclusions:In the context to unavailability of a prognostic tool,urinary leishmanial antigens may offer a better choice and may also be useful as immunoprophylactic candidates. | Vinod Kumar Jalaj Kumar Gour Surabhi Bajpai Manish Mishra Rakesh Kumar Singh | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，5： | 0 |
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