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| 1 | Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis显示文摘Background Stroke is a major cause of death or long-term disability worldwide.Many patients with stroke receive integrative therapy consisting of Western medicine(WM)and routine rehabilitation in conjunction with Chinese medicine(CM),such as acupuncture and Chinese herbal medicine.However,there is no available evidence on the effectiveness of the combined use of WM and CM interventions in stroke rehabilitation.Aims The purpose of this meta-analysis is to evaluate the results of all individual studies to assess the combined use of CM and WM in stroke rehabilitation compared with WM only.Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines were followed.MEDLINE,EMBASE,Cochrane and China National Knowledge Infrastructure(CNKI)were searched.The included outcomes were dependency,motor function,depression and swallowing function.Subgroup analysis was performed,and publication bias was assessed using funnel plots.Summary of review 58 studies and 6339 patients were included in the meta-analysis.Subgroup analysis revealed that combined therapy comprising both acupuncture and WM had a superior effect on improving dependency and swallowing function compared with standard WM therapy alone.Potential superiority of combined therapy comprising CM and WM in improving depression compared with standard WM therapy was also found.Conclusions Our results indicate that the combined use of CM and WM could be more efficacious in stroke rehabilitation compared with the use of WM therapy alone.However,most studies were short in duration(2 to 4 weeks)and prone to different types of biases,which prevents making any conclusion regarding the long-term effects and raises concerns regarding true efficacy in context of high likelihood of Hawthorn bias.So,more randomised controlled trials with more rigorous design and longer duration of treatment and follow-up need to be conducted to compare WM alone versus WM and CM combined. | Linda LD Zhong Ya Zheng Alexander Y Lau Norman Wong Liang Yao Xingyao Wu Tengteng Shao Zhenxing Lu Huijuan Li Chun Sum Yuen Jianwen Guo Suzanne Lo Janita Chau Kam Wa Chan Bacon Fung Leung Ng Zhaoxiang Bian Edwin Chau-leung Yu | 2022 | Stroke & Vascular Neurology2022，7，1： | 7 |
| 2 | Cortical acetylcholine and processing capacity: Effects of cortical cholinergic deafferentation on crossmodal divided attention in rats 显示文摘 | Turchi Janita Sarter Martin | 1997 | Cognitive Brain Research1997，6，2： | 1 |
| 3 | Self - efficacy and quality of life among stoma patients in Hong Kong 显示文摘 | Helen Kit -Man Wu Janita Pak - Chun Chau Sheila Twinn | 2007 | Cancer Nursing2007，30，3： | 1 |
| 4 | Barriers to, and facilitators of, research utilisa- tion : A survey of Hong Kong registered nurses 显示文摘 | Thompson DR Janita P | 2006 | Int J Evid Based Healthc2006，4，2： | 1 |
| 5 | Stakeholder identification in innovation projects: going beyond classification 显示文摘 | JANITA F J | 2006 | European Journal of Innovation Management2006，9，2： | 1 |
| 6 | A Systematic Review of Methods of Eye Irrigation for Adults and Children with Ocu- lar Chemical Burns 显示文摘 | Janita chau Diana Lee Suzanne Lo | 2012 | Worldviews on Evidence - Based Nursing2012，4，3： | 1 |
| 7 | Characterization of mon- oclonal antibodies against prostate specific antigen pro- duced by genetic immunization 显示文摘 | Jari L Pauliina N Janita L | 2004 | J Immunol Methods2004，289，1： | 1 |
| 8 | A feasibility study to investigate the acceptability and potential effectiveness of a telecare service for older people with chronic obstructive pulmonary disease显示文摘 | Janita Pak-Chun Chau Diana Tze-Fan Lee Doris Sau-Fung Yu | 2012 | International journal of medical informatics2012，81，10： | 1 |
| 9 | Barriers to, and facilitators of, re- search utilization:A survey of Hong Kong registered nurses显示文摘 | Thompson D Janita P Lopez V | 2006 | Int J Evid Based Healthc2006，4，2： | 1 |
| 10 | Characterization of monoclonal antibodies against prostate specific antigen produced by genetic im- munization 显示文摘 | Jail L Pauliina N Janita L | 2004 | J Immunol Methods2004，289，1： | 1 |
| 11 | Characterization of monoclonal antibodies against prostate specific antigen produced by genetic immunization 显示文摘 | Jail L Pauliina N Janita L | 2004 | J Immunol Methods2004，289，1： | 1 |
| 12 | Barriers to, and facilitators of, research utilization: A survey of Hong Kong registered nurses 显示文摘 | Thompson D Janita P Lopez V | 2006 | Int J Evid Based Healthc2006，4，2： | 1 |
| 13 | Relationship between self-concept and self-care ability of elderly in a Hong Kong hostel显示文摘 | Wan-Yim I P Janita | 1996 | The Hong Kong Nursing Journal1996，72，： | 1 |
| 14 | A feasibility study to investigate the acceptability and potential effectiveness of a telecare service for older people with chronic obstructive pul- monary disease显示文摘 | Janita Pak-Chun Chau Diana Tze-Fan Lee Doris Sau-l=ung Yu | 2012 | International Journal of Medical In- formatics2012，81，10： | 1 |
| 15 | Determinants of particiFation restric- tion among community dwelling stroke survivors : a path analysis 显示文摘 | Janita PC David R Sheila T | 2009 | Neurology2009，49，9： | 1 |
| 16 | Factor structure of the Chinese version of the Geriatric Depression Scale显示文摘 | Janita Chau Colin R. Martin David R. Thompson Anne M. Chang Jean Woo | 2006 | Psychology, Health & Medicine2006，，1： | 1 |
| 17 | Characterization of monoclonal antibodies against prostate specific antigen produced bygenetic immunization显示文摘 | Jari L Pauliina N Janita L | 2004 | J Immunol Methods2004，289，1： | 1 |
| 18 | Barriers to and Facilitators of, Research Utilization: a Survey of Hong Kong Registered nurses显示文摘 | Thompson D Janita P Lopez V | 2006 | International Journal of Evidence-Based Health- care2006，4，2： | 1 |
| 19 | Factor structure of the Chinese version of the Geriatric Depression Scale显示文摘 | Janita Chau Colin R. Martin David R. Thompson Anne M. Chang Jean Woo | 2006 | Psychology, Health & Medicine2006，，1： | 1 |
| 20 | Depression among Chinese stroke survivorssix months after dis- chargefmm a rehabilitation hospital 显示文摘 | Janita P&C Chau David R Thompson Anne M Chang | 2010 | Journal of Clinical Nurs- ing2010，19，： | 1 |
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