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| 1 | What operation for recurrent rectal prolapse after previous Delorme's procedure? A practical reality显示文摘AIM: To report our experience with perineal repair(Delorme's procedure) of rectal prolapse with particular focus on treatment of the recurrence.METHODS: Clinical records of 40 patients who underwent Delorme's procedure between 2003 and 2014 were reviewed to obtain the following data: Gender; duration of symptoms, length of prolapse, operation time, ASA grade, length of post-operative stay, procedure-related complications, development and treatment of recurrent prolapse. Analysis of post-operative complications, rate and time of recurrence and factors influencing the choice of the procedure for recurrent disease was conducted. Continuous variables were expressed as the median with interquartile range(IQR). Statistical analysis was carried out using the Fisher exact test.RESULTS: Median age at the time of surgery was 76 years(IQR: 71-81.5) and there were 38 females and 2 males. The median duration of symptoms was 6 mo(IQR: 3.5-12) and majority of patients presented electively whereas four patients presented in the emergency department with irreducible rectal prolapse. The median length of prolapse was 5 cm(IQR: 5-7), median operative time was 100 min(IQR: 85-120) and median post-operative stay was 4 d(IQR: 3-6). Approximately16% of the patients suffered minor complications such as- urinary retention, delayed defaecation and infected haematoma. One patient died constituting postoperative mortality of 2.5%. Median follow-up was 6.5 mo(IQR: 2.15-16). Overall recurrence rate was 28%(n = 12). Recurrence rate for patients undergoing an urgent Delorme's procedure who presented as an emergency was higher(75.0%) compared to those treated electively(20.5%), P value 0.034. Median time interval from surgery to the development of recurrence was 16 mo(IQR: 5-30). There were three patients who developed an early recurrence, within two weeks of the initial procedure. The management of the recurrent prolapse was as follows: No further intervention(n = 1), repeat Delorme's procedure(n = 3), Altemeier's procedure(n = 5) and rectopexy with faecal diversion(n = 3). One patient was lost during follow up.CONCLUSION: Delorme's procedure is a suitable treatment for rectal prolapse due to low morbidity and mortality and acceptable rate of recurrence. The management of the recurrent rectal prolapse is often restricted to the pelvic approach by the same patientrelated factors that influenced the choice of the initial operation, i.e., Delorme's procedure. Early recurrence developing within days or weeks often represents a technical failure and may require abdominal rectopexy with faecal diversion. | Muhammad A Javed Faryal G Afridi Dmitri Y Artioukh | 2016 | World Journal of Gastrointestinal Surgery2016，8，7： | 4 |
| 2 | Studies on organic foulants in the seawater feed of reverse osmosis plants of SWCC 显示文摘 | Dalvi A G I AI-Rasheed R Javeed M A | 2000 | Desalination2000，35，13： | 1 |
| 3 | Mortality in broiler chickson feed amended with Fusarium proliferatum culture material orwith purified fumonisin B1 and moniliformin显示文摘 | Javed T Bennett G A Richard J L | 1993 | Mycopathologia1993，123，： | 1 |
| 4 | Physical, electrical and dielectric properties of Ca-substituted strontium hexaferrite (SrFe12O19) nanoparticles synthesized by co-precipitation method 显示文摘 | Javed I M Naeem A M Hussain G I | 2010 | J Magn Magn Mater2010，322，13： | 1 |
| 5 | Comparative prevalence of streak canal and intramammary microorganisms and their contemporaneous association in a dairy cow and buffalo herd lacking mastitis control program显示文摘 | Javed S Muhammad G Saqib M | 2015 | Int J Agric Biol2015，17，： | 1 |
| 6 | Role of Diode Lasers (800- 980 Nm) as Adjuncts to Scaling and Root Planing in the Treatment of Chronic Periodontitis: A Systematic Review显示文摘 | Qadri T Javed F Johannsen G | 2015 | Photomed Laser Surg2015，33，11： | 1 |
| 7 | Synthesis and Blood Glucose Lowering Effect of Novel Pyridazinone Substituted Benzenesulfonylurea Derivatives显示文摘 | Rathish I G Javed K Bano S | 2009 | Eur J Med Chem2009，44，6： | 1 |
| 8 | Studies on organic foulants in the seawater feed of reverse osmosis plants of SWCC显示文摘 | Dalvi A G I Al-Rasheed R Javeed M A | 2000 | Desalination2000，132，13： | 1 |
| 9 | Rutin protects the neural damage induced by transient focal ischemia in rats显示文摘 | Khan MM Ahmad A Ishrat T Khuwaja G Srivastawa P Khan MB Raza SS Javed H Vaibhav K Khan A Islam F | | 0，，： | 1 |
| 10 | Role of diode lasers(800-980 nm)as adjuncts to scaling and root planing in the treatment of chronic periodontitis:a systematic review 显示文摘 | Qadri T Javed F Johannsen G | 2015 | Photomed Laser Surg2015，33，11： | 1 |
| 11 | Ser-262 in human recombinant Tau protein is a markedly more favorable site for phosphorylation by CaMK-Ⅱ than PKA or phK显示文摘 | SIRONI J J YEN S H JAVED A G | 1998 | FEBS Letters1998，436，： | 1 |
| 12 | The Runx2 osteogenic transcription factor regulates matrix metanoproteinase 9 in bone metastatic cancer cells and controls cell invasion 显示文摘 | Pratap J Javed A Languino L R van Wijnen A J Stein J L Stein G S | 2005 | Mol Cell Biol2005，25，： | 1 |
| 13 | Conservative management of signifi- cant supratentorial epidural hematomas in pediatric patients 显示文摘 | Khan MB Riaz M Javed G | 2014 | Childs Nerv Syst2014，30，7： | 1 |
| 14 | Haloacetic acids (HAAs) formation in desalination processes from disinfectants显示文摘 | ABDUL G RADWAN A JAVEED M | 2000 | Desalination2000，129，3： | 1 |
| 15 | Recent advances in the monitoring and control of haemodynamic variables during haemodialysis:A review显示文摘 | Javed F Savkin A V Chan G S H | | 0，，01： | 1 |
| 16 | Differences in soil CO2 flux be- tween different land use types in mid-subtropical China显示文摘 | JAVED I HU R G DU L J | 2008 | Soil Biol- ogy and Biochemistry2008，40，9： | 1 |
| 17 | Energy versus Electron Transfer in Pyridylporphyrin Osmium ( Ⅱ ) Dyads显示文摘 | Hysop A G Orphanide M Javed U | 2003 | Inorg Chim Acta2003，355，： | 1 |
| 18 | Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in β cells and mice显示文摘 | Aggarwal G Ramachandran V Javeed N | 2012 | Gastroenterology2012，143，6： | 1 |
| 19 | Synthesis and antiin-flammatory activity and gastric ulcerogenicity of novel nitric oxidedonating pyrazoline derivatives显示文摘 | Rathish I G Javed K Ahmad S | | 0，，： | 1 |
| 20 | Osteoblast-related transcription factors Runx2 (Cbfal/AMI3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells显示文摘 | BARNES G JAVED A WALLER S | 2003 | Cancer Res2003，63，10： | 1 |
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