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| 1 | Effect of the Inclusion of Chestnut in the Finishing Diet on Volatile Compounds of Dry-Cured Ham from Celta Pig Breed显示文摘The effect of the inclusion of chestnut in pigs finishing diet on volatile compounds of dry-cured Celta ham was studied.Twelve hams of each type(from three different pigs finishing diets:concentrate(CO),mixed(MI)and chestnut(CH)) were used.Volatiles were extracted using a purge-and-trap method and analyzed by gas chromatography/mass spectrometry(GC/MS).Thirty-nine volatile compounds were identified in dry-cured Celta ham samples.Most abundant volatiles in ham samples were aldehydes,which represented respectively,53%(CO),51%(MI)and 46%(CH)of the total volatile composition.With the exception of 2-butenal,2-methyl,all aldehydes were affected by feeding system.On the other hand,hydrocarbons n-alkanes were the second major group in the volatile profile of dry-cured Celta hams and represented 28.9,35.7 and 32.4%of the total volatile composition for CO,MI and CH groups,respectively.Ham samples from chestnut group showed a higher content of alcohols and this result could be related with the inclusion of chestnut in the finishing diet of pigs.Principal component analysis showed a good separation among groups.The discriminant analysis selected eight variables(butanoic acid,hexanal,octanal,nonenal(E),decenal(E),tetradecane,decane trimethyl and pyridine 2-methyl) and calculated two discriminating functions to predict if chestnut has been included in the finishing diet.Thus,it was possible to discriminate between groups fed with finishing diets containing chestnuts in their composition(mixed and chestnut group). | José M Lorenzo Javier Carballo Daniel Franco | 2013 | Journal of Integrative Agriculture2013，12，11： | 22 |
| 2 | Second-line Therapy With Levofloxacin After Failure of Treatment to Eradicate Helicobacter pylori Infection: Time Trends in a Spanish Multicenter Study of 1000 Patients显示文摘 | Javier P. Gisbert ángeles Pérez-Aisa Fernando Bermejo Manuel Castro-Fernández Pedro Almela Jesús Barrio ángel Cosme Inés Modolell Felipe Bory Miguel Fernández-Bermejo Luis Rodrigo Jesús Ortu?o Pilar Sánchez-Pobre Sam Khorrami Alejandro Franco Albert Tomas | 2013 | Journal of Clinical Gastroenterology2013，，2： | 5 |
| 3 | Panda X-III: Searching for neutrinoless double beta decay with high pressure ^(136)Xe gas time projection chambers显示文摘Searching for the neutrinoless double beta decay(NLDBD)is now regarded as the topmost promising technique to explore the nature of neutrinos after the discovery of neutrino masses in oscillation experiments.Panda X-III(particle and astrophysical xenon experiment III)will search for the NLDBD of136Xe at the China Jin Ping Underground Laboratory(CJPL).In the first phase of the experiment,a high pressure gas Time Projection Chamber(TPC)will contain 200 kg,90%136Xe enriched gas operated at10 bar.Fine pitch micro-pattern gas detector(Microbulk Micromegas)will be used at both ends of the TPC for the charge readout with a cathode in the middle.Charge signals can be used to reconstruct the electron tracks of the NLDBD events and provide good energy and spatial resolution.The detector will be immersed in a large water tank to ensure~5 m of water shielding in all directions.The second phase,a ton-scale experiment,will consist of five TPCs in the same water tank,with improved energy resolution and better control over backgrounds. | Xun Chen Chang Bo Fu Javier Galan Karl Giboni Franco Giuliani Ling Hui Gu Ke Han Xiang Dong Ji Heng Lin Jiang Lai Liu Kai Xiang Ni Hiroki Kusano Xiang Xiang Ren Shao Bo Wang Yong Yang Dan Zhang Tao Zhang Li Zhao Xiang Ming Sun Shou Yang Hu Si Yu Jian Xing Long Li Xiao Mei Li Hao Liang Huan Qiao Zhang Ming Rui Zhao Jing Zhou Ya Jun Mao Hao Qiao Si Guang Wang Ying Yuan Meng Wang Amir N.Khan Neill Raper Jian Tang Wei Wang Jia Ning Dong Chang Qing Feng Cheng Li Jian Bei Liu Shu Bin Liu Xiao Lian Wang Dan Yang Zhu Juan F.Castel Susana Cebri'an Theopisti Dafni Javier G.Garza Igor G.Irastorza Francisco J.Iguaz Gloria Luz ′on Hector Mirallas Stephan Aune Eric Berthoumieux Yann Bedfer Denis Calvet Nicole d'Hose Alain Delbart Maria Diakaki Esther Ferrer-Ribas Andrea Ferrero Fabienne Kunne Damien Neyret Thomas Papaevangelou Franck Sabatie Maxence Vanderbroucke AnDi Tan Wick Haxton Yuan Mei Chinorat Kobdaj Yu-Peng Yan | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，6： | 2 |
| 4 | Eutrophication Assessment in Basque Estuaries: Comparing a North American and a European Method显示文摘 | Maialen Garmendia Suzanne Bricker Marta Revilla ángel Borja Javier Franco Juan Bald Victoriano Valencia | 2012 | Estuaries and Coasts2012，，4： | 1 |
| 5 | Gold Nanozymes:From Concept to Biomedical Applications显示文摘In recent years,gold nanoparticles have demonstrated excellent enzyme-mimicking activities which resemble those of peroxidase,oxidase,catalase,superoxide dismutase or reductase.This,merged with their ease of synthesis,tunability,biocompatibility and low cost,makes them excellent candidates when compared with biological enzymes for applications in biomedicine or biochemical analyses.Herein,over 200 research papers have been systematically reviewed to present the recent progress on the fundamentals of gold nanozymes and their potential applications.The review reveals that the morphology and surface chemistry of the nanoparticles play an important role in their catalytic properties,as well as external parameters such as pH or temperature.Yet,real applications often require specific biorecognition elements to be immobilized onto the nanozymes,leading to unexpected positive or negative effects on their activity.Thus,rational design of efficient nanozymes remains a challenge of paramount importance.Different implementation paths have already been explored,including the application of peroxidase-like nanozymes for the development of clinical diagnostics or the regulation of oxidative stress within cells via their catalase and superoxide dismutase activities.The review also indicates that it is essential to understand how external parameters may boost or inhibit each of these activities,as more than one of them could coexist.Likewise,further toxicity studies are required to ensure the applicability of gold nanozymes in vivo.Current challenges and future prospects of gold nanozymes are discussed in this review,whose significance can be anticipated in a diverse range of fields beyond biomedicine,such as food safety,environmental analyses or the chemical industry. | Javier Lou‑Franco Bhaskar Das Christopher Elliott Cuong Cao | 2021 | Nano-Micro Letters2021，13，1： | 1 |
| 6 | Effect of ripening time and type of rennet (farmhouse rennet from kid or commercial calf) on proteolysis during the ripening of León cow milk cheese显示文摘 | Bernardo Prieto Inmaculada Franco José M. Fresno Josefa González Prieto Ana Bernardo Javier Carballo | 2003 | Food Chemistry2003，，3： | 1 |
| 7 | Real-time brake torque estimation for internal combustion engines显示文摘 | Javier Franco Matthew A. Franchek Karolos Grigoriadis | 2007 | Mechanical Systems and Signal Processing2007，，2： | 1 |
| 8 | Monitoring landslides from optical remotely sensed imagery: the case history of Tessina landslide, Italy显示文摘 | Javier Hervás José I Barredo Paul L Rosin Alessandro Pasuto Franco Mantovani Sandro Silvano | 2003 | Geomorphology2003，，1： | 1 |
| 9 | Phytoplankton composition indicators for the assessment of eutrophi- cation in marine waters : Present state and challenges within the Eu- repean directives 显示文摘 | Maialen Garmendia Angel Borja Javier Franco Marta ReviUa | 2013 | Marine Pollution Bulletin2013，66，12： | 1 |
| 10 | Amino acid and soluble nitrogen evolution throughout ripening of Serra da Estrela cheese显示文摘 | Freni K Tavaria Inmaculada Franco F Javier Carballo F Xavier Malcata | 2003 | International Dairy Journal2003，，7： | 1 |
| 11 | Fibrinogen-thrombin collagen patch reinforcement of highrisk colonic anastomoses in rats显示文摘AIM To evaluate the effectiveness of human fibrinogenthrombin collagen patch (TachoSil?) in the reinforcement of high-risk colon anastomoses. METHODS A quasi-experimental study was conducted in Wistar rats (n = 56) that all underwent high-risk anastomoses (anastomosis with only two sutures) after colectomies.The rats were divided into two randomized groups:Control group (24 rats) and treatment group (24 rats).In the treatment group, high-risk anastomosis was reinforced with TachoSil? (a piece of TachoSil? was applied over this high-risk anastomosis, covering the gap). Leak incidence, overall survival, intra-abdominal adhesions, and histologic healing of anastomoses were analyzed. Survivors were divided into two subgroups and euthanized at 15 and 30 d after intervention in order to analyze the adhesions and histologic changes.RESULTS Overall survival was 71.4% and 57.14% in the TachoSil? group and control group, respectively (P = 0.29); four rats died from other causes and six rats in the treatment group and 10 in the control group experienced colonic leakage (P > 0.05). The intra-abdominal adhesion score was similar in both groups, with no differences between subgroups. We found non-significant differences in the healing process according to the histologic score used in both groups (P = 0.066). CONCLUSION In our study, the use of TachoSil? was associated with a non-statistically significant reduction in the rate of leakage in high-risk anastomoses. TachoSil? has been shown to be a safe product because it does not affect the histologic healing process or increase intra-abdominal adhesions. | Juan Manuel Suárez-Grau Carlos Bernardos García Carmen Cepeda Franco Cristina Mendez García Salud García Ruiz Fernando Docobo Durantez Salvador Morales-Conde Javier Padillo Ruiz | 2016 | World Journal of Gastrointestinal Surgery2016，8，9： | 1 |
| 12 | Biogenic amine content during the manufacture of dry-cured lacón, a Spanish traditional meat product: Effect of some additives显示文摘 | José M. Lorenzo Sidonia Martínez Inmaculada Franco Javier Carballo | 2007 | Meat Science2007，，2： | 1 |
| 13 | Nanozymes in Point-of-Care Diagnosis:An Emerging Futuristic Approach for Biosensing显示文摘Nanomaterial-based artificial enzymes(or nanozymes) have attracted great attention in the past few years owing to their capability not only to mimic functionality but also to overcome the inherent drawbacks of the natural enzymes.Numerous advantages of nanozymes such as diverse enzyme-mimicking activities,low cost,high stability,robustness,unique surface chemistry,and ease of surface tunability and biocompatibility have allowed their integration in a wide range of biosensing applications. Several metal,metal oxide,metal–organic framework-based nanozymes have been exploited for the development of biosensing systems,which present the potential for point-of-care analysis. To highlight recent progress in the field,in this review,more than 260 research articles are discussed systematically with suitable recent examples,elucidating the role of nanozymes to reinforce,miniaturize,and improve the performance of point-of-care diagnostics addressing the ASSURED(a ordable,sensitive,specific,user-friendly,rapid and robust,equipment-free and deliverable to the end user) criteria formulated by World Health Organization. The review reveals that many biosensing strategies such as electrochemical,colorimetric,fluorescent,and immunological sensors required to achieve the ASSURED standards can be implemented by using enzyme-mimicking activities of nanomaterials as signal producing components. However,basic system functionality is still lacking. Since the enzyme-mimicking properties of the nanomaterials are dictated by their size,shape,composition,surface charge,surface chemistry as well as external parameters such as pH or temperature,these factors play a crucial role in the design and function of nanozyme-based point-of-care diagnostics. Therefore,it requires a deliberate exertion to integrate various parameters for truly ASSURED solutions to be realized. This review also discusses possible limitations and research gaps to provide readers a brief scenario of the emerging role of nanozymes in state-of-the-art POC diagnosis system development for futuristic biosensing applications. | Bhaskar Das Javier Lou Franco Natasha Logan Paramasivan Balasubramanian Moon Il Kim Cuong Cao | 2021 | Nano-Micro Letters2021，13，12： | 1 |
| 14 | Economic analysis of scenarios for the sustainability of extensive livestock farming in Spain under the CAP显示文摘 | Juan Agustín Franco Paula Gaspar Francisco Javier Mesias | 2012 | Ecological Economics2012，，： | 1 |
| 15 | Real-time brake torque estimation for internal combustion engines显示文摘 | Javier Franco Matthew A. Franchek Karolos Grigoriadis | 2007 | Mechanical Systems and Signal Processing2007，，2： | 1 |
| 16 | A new approach to landslide geom~wphological mapping using the Open Source software in the Olver a area ( Cadiz, Spain ) 显示文摘 | Franco Mantovani Francisco Javier Gracia Pietro Domenico de Cosmo | 2010 | Landslides2010，7，1： | 1 |
| 17 | Amino Acid and Soluble Nitrogen Evolution Throughout Ripening of Serra Da Estrela Cheese 显示文摘 | TAVARIA F K FRANCO I JAVIER CARBALLO F | 2003 | International Dairy Journal2003，13，7： | 1 |
| 18 | The Study of Technical and Scientific Translation: An Examination of its Historical Development 显示文摘 | Franco Aixeld Javier | 2004 | Jostrans : The Journal of Specialised Translation2004，，1： | 1 |
| 19 | Screening for Human Milk Amino Acids by HPLC-ESI-MS/MS显示文摘 | Cristina Sánchez Javier Cubero Javier Sánchez Lourdes Franco Ana Rodríguez Montserrat Rivero Carmen Barriga | 2012 | Food Analytical Methods2012，，2： | 1 |
| 20 | Implementation of the European water framework directive from the Basque country (northern Spain): a methodological approach显示文摘 | ángel Borja Javier Franco Victoriano Valencia Juan Bald I?igo Muxika Mar??a Jesús Belzunce Oihana Solaun | 2003 | Marine Pollution Bulletin2003，，3： | 1 |
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