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| 1 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 2 | Pancreatic ductal adenocarcinoma: Long-term survival does not equal cure显示文摘 | Cristina R. Ferrone Rafael Pieretti-Vanmarcke Jordan P. Bloom Hui Zheng Jackye Szymonifka Jennifer A. Wargo Sarah P. Thayer Gregory Y. Lauwers Vikram Deshpande Mari Mino-Kenudson Carlos Fernández-del Castillo Keith D. Lillemoe Andrew L. Warshaw | 2012 | Surgery2012，，： | 2 |
| 3 | Effect of Shock-activation of Post-shock Reaction Synthesis of Ternary Ceramics显示文摘 | Jennifer L Jordan Naresh N Thadhani | 2001 | Shock Compression of Condensed Matter2001，27，5： | 1 |
| 4 | Feminist Fantasies:Zora Neale Hurston's Their Eyes Were Watching God显示文摘 | Jordan Jennifer | 1998 | Tulsa Studies in Women''s Literature1998，，1： | 1 |
| 5 | Taking the First Step Toward a Moral Ac- tion: A Review of Moral Sensitivity Measurement Across Domains 显示文摘 | Jennifer Jordan | 2007 | The Journal of Genetic Psychology2007，168，3： | 1 |
| 6 | CO 2 , CO, and Hg emissions from the Truman Shepherd and Ruth Mullins coal fires, eastern Kentucky, USA显示文摘 | Jennifer M.K. O’Keefe Kevin R. Henke James C. Hower Mark A. Engle Glenn B. Stracher J.D. Stucker Jordan W. Drew Wayne D. Staggs Tiffany M. Murray Maxwell L. Hammond Kenneth D. Adkins Bailey J. Mullins Edward W. Lemley | 2009 | Science of the Total Environment2009，，7： | 1 |
| 7 | Comparison of open and closed hyperthermic intraperitoneal chemotherapy: Results from the United States hyperthermic intraperitoneal chemotherapy collaborative显示文摘BACKGROUND Cytoreductive surgery(CRS)with hyperthermic intraperitoneal chemotherapy(HIPEC)for peritoneal carcinomatosis can be performed in two ways:Open or closed abdominal technique.AIM To evaluate the impact of HIPEC method on post-operative and long-term survival outcomes.METHODS Patients undergoing CRS with HIPEC from 2000-2017 were identified in the United States HIPEC collaborative database.Post-operative,recurrence,and overall survival outcomes were compared between those who received open vs closed HIPEC.RESULTS Of the 1812 patients undergoing curative-intent CRS and HIPEC,372(21%)patients underwent open HIPEC and 1440(79%)underwent closed HIPEC.There was no difference in re-operation or severe complications between the two groups.Closed HIPEC had higher rates of 90-d readmission while open HIPEC had a higher rate of 90-d mortalities.On multi-variable analysis,closed HIPEC technique was not a significant predictor for overall survival(hazards ratio:0.75,95%confidence interval:0.51-1.10,P=0.14)or recurrence-free survival(hazards ratio:1.39,95%confidence interval:1.00-1.93,P=0.05)in the entire cohort.These findings remained consistent in the appendiceal and the colorectal subgroups.CONCLUSION In this multi-institutional analysis,the HIPEC method was not independently associated with relevant post-operative or long-term outcomes.HIPEC technique may be left to the discretion of the operating surgeon. | Jennifer L Leiting Jordan M Cloyd Ahmed Ahmed Keith Fournier Andrew J Lee Sophie Dessureault Seth Felder Jula Veerapong Joel M Baumgartner Callisia Clarke Harveshp Mogal Charles A Staley Mohammad Y Zaidi Sameer H Patel Syed A Ahmad Ryan J Hendrix Laura Lambert Daniel E Abbott Courtney Pokrzywa Mustafa Raoof Christopher J LaRocca Fabian M Johnston Jonathan Greer Travis E Grotz | 2020 | World Journal of Gastrointestinal Oncology2020，12，7： | 1 |
| 8 | PAX2 Loss by Immunohistochemistry Occurs Early and Often in Endometrial Hyperplasia显示文摘 | Kimberly H. Allison Kristen Upson Susan D. Reed Carolyn D. Jordan Katherine M. Newton Jennifer Doherty Elizabeth M. Swisher Rochelle L. Garcia | 2012 | International Journal of Gynecological Pathology2012，，2： | 1 |
| 9 | Arsenic speciation in freshwater fish:challenges and research needs显示文摘Food and water are the main sources of human exposure to arsenic.It is important to determine arsenic species in food because the toxicities of arsenic vary greatly with its chemical speciation.Extensive research has focused on high concentrations of arsenic species in marine organisms.The concentrations of arsenic species in freshwater fish are much lower,and their determination presents analytical challenges.In this review,we summarize the current state of knowledge on arsenic speciation in freshwater fish and discuss challenges and research needs.Fish samples are typically homogenized,and arsenic species are extracted using water/methanol with the assistance of sonication and enzyme treatment.Arsenic species in the extracts are commonly separated using high-performance liquid chromatography(HPLC)and detected using inductively coupled plasma mass spectrometry(ICPMS).Electrospray ionization tandem mass spectrometry,used in combination with HPLC and ICPMS,provides complementary information for the identification and characterization of arsenic species.The methods and perspectives discussed in this review,covering sample preparation,chromatography separation,and mass spectrometry detection,are directed to arsenic speciation in freshwater fish and applicable to studies of other food items.Despite progress made in arsenic speciation analysis,a large fraction of the total arsenic in freshwater fish remains unidentified.It is challenging to identify and quantify arsenic species present in complex sample matrices at very low concentrations.Further research is needed to improve the extraction efficiency,chromatographic resolution,detection sensitivity,and characterization capability. | Karen S.Hoy Tetiana Davydiuk Xiaojian Chen Chester Lau Jordan R.M.Schofield Xiufen Lu Jennifer A.Graydon Ruth Mitchell Megan Reichert X.Chris Le | 2023 | Food Quality and Safety2023，7，3： | 0 |
| 10 | A Randomized Controlled Trial of Mindfulness in Recovery from Colorectal Cancer显示文摘Objective:This study examined whether a 4-week group-based mindfulness intervention would be superior in reducing psychological distress in colorectal cancer(CRC)patients compared to a psychoeducation and cognitive behavioural skills learning support active control group.Methods:Patients with CRC were randomized via Computerised Permuted Block Randomisation to mindfulness or active control groups(2-h weekly sessions over 4 weeks).Outcomes were measured pre-intervention,and 8 weeks and 6 months post-baseline.The primary outcome was psychological distress measured by the Hospital Anxiety and Depression Scale.Secondary outcomes were generic quality of life(QoL),disease specific QoL,mindfulness,and intervention credibility and acceptability.Results:Sixty-eight participants were randomized to mindfulness(n=35)or active control group(n=33).Uptake of potentially eligible patients consenting was low(28.0%)and the dropout rate was 33.8%.Depression scores were reduced in both groups at week 8(P=0.020).Control participants had greater improvement in generic mental QoL scores at week 8 than mindfulness(P=0.023).In disease specific QoL,there was reduction in impotence symptom in the mindfulness group(P=0.022)and reduction in faecal incontinence in the control group(P=0.019).The embarrassment symptom had a significantly lower increase in the mindfulness group at week 8 compared to the control group(P=0.009).Both groups rated the treatments as credible and acceptable.Conclusions:Mindfulness was not superior to the active control group in terms of alleviating psychological distress but both treatments were associated with some improvements in depression.There was low uptake of both interventions.(Trial registration number:ACTRN12616001033437) | Andrew McCombie Jennifer Jordan Roger Mulder Kishion Dee Ee Lin Ong Fernanda Fernandez Zimmermann Chris Frampton Frank Frizelle | 2023 | Chinese Journal of Integrative Medicine2023，29，7： | 0 |
| 11 | Immunotherapy in hepatocellular carcinoma: Combination strategies显示文摘Liver cancer is one of the most common causes of cancer death globally,and its incidence in the United States is increasing.Patients with advanced hepatocellular carcinoma(HCC)who are not candidates for surgical resection,liver transplant,or locoregional therapies can be treated with systemic therapies.Multiple agents,including sorafenib,lenvatinib,and regorafenib are approved for use as either first-or second-line therapy in this patient population,but all have relatively modest survival benefits.HCC is potentially susceptible to therapy with checkpoint inhibitors,including agents such as nivolumab and pembrolizumab,which are both approved by the Food and Drug Administration for patients previously treated with sorafenib but have not demonstrated superior overall survival in phase III trials.It is clear that more effective approaches are needed to potentiate the effects of checkpoint inhibitors in patients with HCC.This review will outline and appraise the current literature on the use of checkpoint inhibitors in HCC as part of a combination treatment involving an additional mode of therapy.The list of agents that can be paired with checkpoint inhibitors includes an additional checkpoint inhibitor,vascular endothelial growth factor or vascular endothelial growth factor receptor inhibitors,tyrosine kinase inhibitors,OX-40 agonists,and PT-112 inhibitors.The main non-pharmacologic therapies currently being studied for inclusion in a combination strategy include radiation therapy,trans-arterial chemoembolization,and ablation. | Alexander Claudius Jordan Jennifer Wu | 2020 | World Journal of Meta-Analysis2020，8，3： | 0 |
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