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| 1 | Research on geo-electrical resistivity observation system specially used for earthquake monitoring in China显示文摘This paper deals with the design and development of the observational system of geo-electrical resistivity on the basis of the demands for exploring the temporal variations of electrical properties of Earth media in the fixed points of the networks,which would be associated with the earthquake preparation.The observation system is characterized by the high accuracy in measurement,long term stability in operation and high level of rejection to the environmental interference.It consists of three main parts,configuration system measurement system,the calibration and inspection system. | Jialiu Zhao Lanwei Wang Jiadong Qian | 2011 | Earthquake Science2011，24，6： | 7 |
| 2 | Testing and modeling of soil-structure interface 显示文摘 | HU Liming PU Jialiu | 2004 | Journal of Geotechnical and Geoenvironmental Engineering2004，130，8： | 1 |
| 3 | Testing and modeling of soilstructure interface显示文摘 | HU Liming PU Jialiu | 2004 | Journal of Geotechnical and Geoenvironmental Engineering2004，130，8： | 1 |
| 4 | Hail growth in a three-dimensional cloud model显示文摘 | Xu Jialiu | 1983 | J Atmos Sci1983，40，： | 1 |
| 5 | Quantitative Measurements of the Ciliary Body in Eyes with Malignant Glaucoma after Trabeculectomy Using Ultrasound Biomicroscopy显示文摘 | Zhonghao Wang Jingjing Huang Jialiu Lin Xuanwei Liang Xiaoyu Cai Jian Ge | 2013 | Ophthalmology2013，，： | 1 |
| 6 | Behav- ior of plastic concrete diaphragm and walls in Three Gorge Project 显示文摘 | Zhang Jianhong Hu Liming Pu Jialiu | 1999 | Tsinghua Science and Technology1999，4，1： | 1 |
| 7 | Study on TiN precipitation during solidification of hypereutectoid tire cord steel 显示文摘 | Lei Jialiu Xue Zhengliang Jiang Yuedong | 2012 | Metalurgia International2012，17，9： | 1 |
| 8 | Development and in‐house validation of the event‐specific qualitative and quantitative PCR detection methods for genetically modified cotton MON15985显示文摘 | LingxiJiang LitaoYang JunRao JinchaoGuo ShuWang JiaLiu SeonghunLee DabingZhang | 2010 | J Sci Food Agric2010，，3： | 1 |
| 9 | Production of neutralizing monoclonal antibody against human vascular endothelial growth factor receptor Ⅱ显示文摘AIM: To prepare neutralizing monoclonal antibody (mAb) against extracellular immunoglobulin (Ig)-like domain Ⅲ of vascular endothelial growth factor receptor KDR and study its biological activity. METHODS: Soluble KDR Ig domain III (KDR-Ⅲ) fusion protein was expressed in E Coli and purified from the bacterial periplasmic extracts via an affinity chromatography. Monoclonal antibodies against KDR-Ⅲ were prepared by hybridoma technique. ELISA and FACS analysis were used to identify its specificity. Immunoprecipitation and [^3H]-thymidine incorporation assay were also used to detect the activity of anti-KDR mAb blocking the phosphorylation of KDR tyrosine kinase receptor and the influence on vascular endothelial growth factor-induced mitogenesis of human endothelial cells. RESULTS: A monoclonal antibody, Ycom1D3 (IgG1), was generated from a mouse immunized with the recombinant KDR-Ⅲ protein. YcomlD3 bound specifically to both the soluble KDR-Ⅲ and the cell-surface expressed KDR. Ycom1D3 effectively blocked VEGF/KDR interaction and inhibited VEGF-stimulated KDR activation in human endothelial cells. Furthermore, the antibody efficiently neutralized VEGF-induced mitogenesis of human endothelial cells. CONCLUSION: Our results suggest that the anti-KDR mAb, Ycom1D3, has potential applications in the treatment of cancer and other diseases where pathological angiogenesis is involved. | RongLI Dong-shengXIONG Xiao-fengSHAO JiaLIU Yuan-fuXU Yuan-shengXU Han-zhiLIU Zhen-pingZHU Chun-zhengYANG | 2004 | Acta Pharmacologica Sinica2004，25，10： | 1 |
| 10 | Bog Bilberry (Vaccinium uliginosum?L.) Extract Reduces Cultured Hep‐G2, Caco‐2, and 3T3‐L1 Cell Viability, Affects Cell Cycle Progression, and Has Variable Effects on Membrane Permeability显示文摘 | JiaLiu WeiZhang HaoJing David G.Popovich | 2010 | Journal of Food Science2010，，3： | 1 |
| 11 | Testing and modeling of soil-structure interface显示文摘 | Hu Liming Pu Jialiu | 2004 | Journal of Geotechnical and Geoenvironmental Engineering2004，130，8： | 1 |
| 12 | Application of damage model for soil-structure interface显示文摘 | Hu Liming Pu Jialiu | 2003 | Computers and Geotechnics2003，30，1： | 1 |
| 13 | Inflation & Growth in a Service Economy显示文摘 | Jialius D eAnne John Bult er | 1998 | Bank of England1998，38，： | 1 |
| 14 | Behavior of plastic concrete diaphragm and walls in Three Gorge Project 显示文摘 | ZHANG Jianhong HU Liming PU Jialiu | 1999 | Tsinghua Science and Technology1999，4，1： | 1 |
| 15 | An improved transfer matrix-direct integration method for rotor dynamics显示文摘 | Gu Jialiu | 1986 | Jounal of Vibration Acoustic Stress and Reliability in Design1986，108，2： | 1 |
| 16 | Application of damage model for soilstructure interface 显示文摘 | Hu Liming Pu Jialiu | 2003 | Computers and Geotechnics2003，30，1： | 1 |
| 17 | 131I therapy for 345 pa- tients with refractory severe hyperthyroidism:Without antithyroid drug pretreatment显示文摘 | Yong Ding Jialiu Xing Yi Fang | 2016 | Experimental Biology and Medicine2016，241，3： | 1 |
| 18 | Decabromodiphenyl ether induces the chromosome association disorders of spermatocytes and deformation failures of spermatids in mice显示文摘The environmental presence of decabromodiphenyl ether(BDE-209),which is toxic to the male reproductive system,is widespread.The current study investigated its mechanism of toxicity in mice.The results showed,that BDE-209 induced DNA damage,decreased the expression of the promoter of meiosis spermatogenesis-and oogenesis-specific basic helix-loop-helix 1(Sohlh1),meiosis related-factors Lethal(3)malignant brain tumor like 2(L3MBTL2),PIWI-like protein 2(MILI),Cyclin-dependent kinase 2(CDK2),Cyclin A,synaptonemal complex protein 1(SYCP1)and synaptonemal complex protein 3(SYCP3),and caused spermatogenic cell apoptosis,resulting in a decrease in sperm quantity and quality.Furthermore,BDE-209 downregulated the levels of anaphase-promoting complex/cyclosome(APC/C),increased the expression of PIWI-like protein 1(MIWI)in the cytoplasm of elongating spermatids,and decreased the nuclear levels of RING finger protein 8(RNF8),ubiquitinated(ub)-H2A/ub-H2B,and Protamine 1(PRM1)/Protamine 2(PRM2),while increasing H2A/H2B nuclear levels in spermatids.The reproductive toxicity was persistent for 50 days following the withdrawal of BDE-209 exposure.The results suggested that BDE-209 inhibits the initiation of meiosis by decreasing the expression of Sohlh1.Furthermore,the reduced expression of L3MBTL2 inhibited the formation of chromosomal synaptonemal complexes by depressing the expression of meiosis regulators affecting the meiotic progression and also inhibited histone ubiquitination preventing the replacement of histones by protamines,by preventing RNF8 from entering nuclei,which affected the evolution of spermatids into mature sperm. | Jinglong Xue Xiangyang Li Yafei Chi Leqiang Gao Yue Zhang Yan Wang Moxuan Zhao Jialiu Wei Zhixiong Shi Xianqing Zhou | 2024 | Journal of Environmental Sciences2024，，4： | 0 |
| 19 | The Puccinia striiformis effector Hasp98 facilitates pathogenicity by blocking the kinase activity of wheat TaMAPK4显示文摘The obligate biotrophic fungus Puccinia striiformis f.sp.tritici(Pst)employs virulence effectors to disturb host immunity and causes devastating stripe rust disease.However,our understanding of how Pst effectors regulate host defense responses remains limited.In this study,we determined that the Pst effector Hasp98,which is highly expressed in Pst haustoria,inhibits plant immune responses triggered by flg22or nonpathogenic bacteria.Overexpression of Hasp98 in wheat(Triticum aestivum)suppressed avirulent Pst-triggered immunity,leading to decreased H2O2accumulation and promoting P.striiformis infection,whereas stable silencing of Hasp98 impaired P.striiformis pathogenicity.Hasp98 interacts with the wheat mitogenactivated protein kinase TaMAPK4,a positive regulator of plant resistance to stripe rust.The conserved TEY motif of TaMAPK4 is important for its kinase activity,which is required for the resistance function.We demonstrate that Hasp98inhibits the kinase activity of TaMAPK4 and that the stable silencing of TaMAPK4 compromises wheat resistance against P.striiformis.These results suggest that Hasp98 acts as a virulence effector to interfere with the MAPK signaling pathway in wheat,thereby promoting P.striiformis infection. | Jinping Wei Xiaodong Wang Zeyu Hu Xiaojie Wang Jialiu Wang Jianfeng Wang Xueling Huang Zhensheng Kang Chunlei Tang | 2023 | Journal of Integrative Plant Biology2023，65，1： | 0 |
| 20 | RHEOLOGICAL BEHAVIOURS OF CAST STEEL DURING SOLIDIFICATION显示文摘The stress-strain relation for cast low alloy carbon steel at solidification temperature hasbeen examined by the authors’ own desingned apparatus for rheological propertiesmeasurement.The rheology model,the stress-strain constitutive equation and the rheologicalparameters therefrom of the cast steel were proposed.Thus the theoretical basis and calcula-ting data for computerized s#nulation on the stress-strain relation and thermal cracking ofthe cast steel were suggested. | LIN Jialiu ZHU Shigen YU Zhenzong Tsinghua University,Beijing,China | 1992 | Acta Metallurgica Sinica(English Letters)1992，5，8： | 0 |
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