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| 1 | Fluid Inclusion and H-O Isotope Geochemistry of the Phapon Gold Deposit, NW Laos: Implications for Fluid Source and Ore Genesis显示文摘The Phapon gold deposit, located in northern Laos, is a unique large-scale gold deposit in Luang Prabang-Loei metallogenic belt. It is hosted in the Lower Permian limestone and controlled by a NE-trending ductile-brittle fault system. There are three types of primary ore including auriferous calcite vein type, disseminated type, and breccia type, and the first two are important in the Phapon gold deposit. Based on fluid inclusion petrography and microthermometry, three types of primary fluid inclusions including type 1 liquid-rich aqueous, type 2 vapor-rich aqueous and type 3 daughter mineralbearing aqueous were identified in hydrothermal calcite grains. The ore-forming fluids are normally homogeneous, as indicated by the widespread type 1 inclusions with identical composition. The coexistence of type 1 and type 2 inclusions, showing similar final homogenization temperature but different compositions, indicate that fluid immiscibility did locally take place in both two types of ores. The results of microthermometry and H-O isotopes geochemistry indicate that there are little differences on ore-fluid geochemistry between the auriferous calcite vein-type and disseminated type ores. The oreforming fluids are characterized by medium-low temperatures(157–268 oC) and low salinity(1.6 wt.%–9.9 wt.% NaCl eq.). It is likely to have a metamorphic-dominant mixed source, which could be associated with dehydration and decarbonisation of Lower Permian limestone and Middle–Upper Triassic sandstones during the dynamic metamorphism. The fluid-wallrock interaction played a major role, and the locally occurred fluid-immiscible processes played a subordinate role in gold precipitation. Combined with the regional and ore deposit geology, and ore-fluid geochemistry, we suggest that the Phapon gold deposit is best considered to be a member of the epizonal orogenic deposit class. | Linnan Guo Shusheng Liu Lin Hou Jieting Wang Meifeng Shi Qiming Zhang Fei Nie Yongfei Yang Zhimin Peng | 2019 | Journal of Earth Science2019，30，1： | 11 |
| 2 | miR-23b promotes cutaneous wound healing through inhibition of the inflammatory responses by targeting ASK1显示文摘Wound healing is a complicated event that develops in three overlapping phases:inflammatory, proliferative,and remodeling.MicroRNAs (miRNAs)have been proved to play an important role in the healing process of skin trauma,and alteration of specific miRNA expression during different phases may be associated with abnormal wound healing.In this study,we determined the variation of miR-23b expression after trauma in normal mice and in cultured cells exposed to lipopolysaccharide.We further demonstrated that excessive miR-23b could significantly accelerate wound healing in vivo.Up-regulation of miR-23b decreases infiltration of inflammatory cells,as evidenced by pathologic staining.Meanwhile,miR-23b could significantly inhibit the expression of pro-inflammatory cytokines,including TNF-α,IL-1β,IL-6,and Ccl2,and significantly increase antiinflammatory factor IL-10.Furthermore,miR-23b could also promote α-SMA expression in a fiber pattern and increase the expression of Col1a1 and Col3a1.Importantly,we also showed that miR- 23b could inhibit inflammation to promote wound healing by targeting apoptotic signal-regulating kinase 1 (ASK1).Notably,knockdown of ASK1 could reduce inflammation factor expression in vitro.Together,our data reveal that miR-23b is a potent therapeutic agent for cutaneous wound healing that shortens the period of inflammatory responses and promotes keratinocyte migration for the re-epithelialization of wound sites. | Hongzhi Li Xiao Han Kuiyang Zuo Li Li Jieting Liu Xiaohuan Yuan Yongchao Shen Minglong Shao Daxin Pang Yanhui Chu Binghai Zhao | 2018 | Acta Biochimica et Biophysica Sinica2018，50，11： | 5 |
| 3 | Research on Causality Relationship of Low-Carbon Development and Industrial Structure显示文摘 | Liu Chunmei Duan Maosheng Zhang Xiliang Zhou Jieting Zhang Tianhou Yang Guang Ou Xunmin Wang Enchuang Dai Chunyan Guo Shiyi Hu Guangping Zhou Lingling Qi Tianyu | 2011 | Procedia Environmental Sciences2011，，： | 1 |
| 4 | Empirical Research on the Contributions of Industrial Restructuring to Low-Carbon De-velopment显示文摘 | Liu Chunmei Duan Maosheng Zhang Xiliang Zhou Jieting Zhou Lingling Hu Guangping | | 0，，5： | 1 |
| 5 | Identification and expression profile of GbAGL2, a C-class gene from G ossypium barbadense显示文摘 | Xiang Liu Kaijing Zuo Fei Zhang Ying Li Jieting Xu Lida Zhang Xiaofen Sun Kexuan Tang | 2009 | Journal of Biosciences2009，，6： | 1 |
| 6 | Output-based al- lowance allocations under China' s carbon intensity target 显示文摘 | ZHOU Jieting DUAN Maosheng LIU Chunmei | 2011 | Energy Procedia2011，5，1： | 1 |
| 7 | Empirical Research on the Contributions of Industrial Restructuring to Low-Carbon Development显示文摘 | Liu Chunmei Duan Maosheng Zhang Xiliang Zhou Jieting Zhou Lingling Hu Guangping | 2011 | Energy Procedia2011，5，： | 1 |
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