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| 1 | Selective COX-2 inhibitor,NS-398,suppresses cellular proliferation in human hepatocellular carcinoma cell lines via cell cycle arrest显示文摘AIM: To investigate the growth inhibitory mechanism of NS-398, a selective cyclooxygenase-2 (COX-2) inhibitor, in two hepatocellular carcinoma (HCC) cell lines (HepG2 and Huh7). METHODS: HepG2 and Huh7 cells were treated with NS-398. Its effects on cell viability, cell proliferation, cell cycles, and gene expression were respectively evaluated by water-soluble tetrazolium salt (WST-1) assay, 4’-6-diamidino-2-phenylindole (DAPI) staining, flow cytometer analysis, and Western blotting, with dimethyl sulfoxide (DMSO) as positive control. RESULTS: NS-398 showed dose- and time-dependent growth-inhibitory effects on the two cell lines. Proliferating cell nuclear antigen (PCNA) expressions in HepG2 and Huh7 cells, particularly in Huh7 cells were inhibited in a time- and dose-independent manner. NS-398 caused cell cycle arrest in the G1 phase with cell accumulation in the sub-G1 phase in HepG2 and Huh7 cell lines. No evidence of apoptosis was observed in two cell lines. CONCLUSION: NS-398 reduces cell proliferation by inducing cell cycle arrest in HepG2 and Huh7 cell lines, and COX-2 inhibitors may have potent chemoprevention effects on human hepatocellular carcinoma. | Ji Yeon Baek Wonhee Hur Jin Sang Wang Si Hyun Bae Seung Kew Yoon | 2007 | World Journal of Gastroenterology2007，13，8： | 27 |
| 2 | Intrahepatic biliary cystadenoma:Is there really an almost exclusively female predominance?显示文摘Biliary cystic tumors,such as cystadenomas and cystadenocarcinomas,are rare cystic tumors of the liver,accounting for less than 5% of all intrahepatic cysts of biliary origin.Biliary cystadenomas have been known to occur predominantly in women (> 85%),and 38%-44% of biliary cystadenocarcinomas have occurred in males.We wrote this letter to comment on a brief article (World J Gasteroenterol 2011 January 21;17(3):361-365) regarding a case of intrahepatic biliary cystic neoplasm treated with surgery.The adenoma-carcinoma sequence is the possible mechanism of carcinogenesis.If the carcinogenesis of biliary cystadenocarcinoma occurs in the adenoma-carcinoma sequence,we believe that the male-to-female ratio of cystadenoma should be higher than the incidence rate that has been reported to date. | Ho Hyun Kim Young Hoe Hur Yang Seok Koh Chol Kyoon Cho Jin Woong Kim | 2011 | World Journal of Gastroenterology2011，17，25： | 12 |
| 3 | The growth inhibitory effect of lapatinib, a dual inhibitor of EGFR and HER2 tyrosine kinase, in gastric cancer cell lines显示文摘 | Jin Won Kim Hwang-Phill Kim Seock-Ah Im Soyeong Kang Hyung Seok Hur Young-Kwang Yoon Do-Youn Oh Jee Hyun Kim Dong Soon Lee Tae-You Kim Yung-Jue Bang | 2008 | Cancer Letters2008，，2： | 2 |
| 4 | Antimicrobial resistance of Salmonella isolated from food animals: A review显示文摘 | Jin Hur Chetan Jawale John Hwa Lee | 2011 | Food Research International2011，，2： | 2 |
| 5 | Laparoscopy-Assisted Endoscopic Full-Thickness Resection with Basin Lymphadenectomy Based on Sentinel Lymph Nodes for Early Gastric Cancer显示文摘 | Hoon Hur Sun Gyo Lim Cheulsu Byun Joon Koo Kang Sung Jae Shin Kee Myung Lee Jin Hong Kim Yong Kwan Cho Sang-Uk Han | 2014 | Journal of the American College of Surgeons2014，，3： | 2 |
| 6 | Robotic versus laparoscopic coloanal anastomosis with or without intersphincteric resection for rectal cancer显示文摘 | Se Jin Baek Sami AL-Asari Duck Hyoun Jeong Hyuk Hur Byung Soh Min Seung Hyuk Baik Nam Kyu Kim | 2013 | Surgical Endoscopy2013，，11： | 2 |
| 7 | Antimicrobial resistance of Salmonella isolated from food animals: A review显示文摘 | Jin Hur Chetan Jawale John Hwa Lee | 2011 | Food Research International2011，，2： | 2 |
| 8 | Comparative study of resection and radiofrequency ablation in the treatment of solitary colorectal liver metastases显示文摘 | Hyuk Hur Yong Taek Ko Byung Soh Min Kyung Sik Kim Jin Sub Choi Seung Kook Sohn Chang Hwan Cho Heung Kyu Ko Jong Tai Lee Nam Kyu Kim | 2009 | The American Journal of Surgery2009，，6： | 2 |
| 9 | Comparison of the structural, spectroscopic and phenanthrene binding characteristics of humic acids from soils and lake sediments显示文摘 | Jin Hur Doo-Hee Lee Hyun-Sang Shin | 2009 | Organic Geochemistry2009，，10： | 1 |
| 10 | Importance of nutrient availability for soluble microbial products formation during a famine period of activated sludge:Evidence from multiple analyses显示文摘Much remains unknown about compositional variations in soluble microbial products(SMP)with the shift of the substrate condition from a feast to a famine phase in biological treatment systems.This study demonstrated that the formation of SMP could be suppressed by up to 75%during the famine phase with the addition of essential nutrients.In contrast,presence of electron acceptor did not play any significant role during the stress condition,showing the similar amounts of SMP(r=0.98,p<0.05)formation between the bioreactors supplied with air and N2.The SMP formed in the famine phase was more biorefractory in the famine versus the feast phase with a linear correlation shown between the production and their aromatic structures in the composition(R^2>0.95).The fluorescence excitation-emission matrix coupled with parallel factor analysis(EEM-PARAFAC)revealed the presence of four different fluorescent components,including two protein-like(C1 and C4),fulvic-like(C2),and humic-like(C3)components,in the SMP and bEPS formed at different conditions.Both C1 and C4 showed increasing trends(R^2>0.95)with the length of starvation in the bioreactors without essential nutrients.Nutrient availability was found to be a key factor to quench the production of large-sized biopolymers.This study provides a wealth of information on operation conditions of activated sludge treatment systems to minimize large sized SMP molecules(particularly proteins),which typically exert many environmental concerns to effluent organic matter quality. | Tahir Maqbool Jinwoo Cho Jin Hur | 2019 | Journal of Environmental Sciences2019，31，10： | 1 |
| 11 | Characteristic Analysis of Interior Permanent-Magnet Synchronous Motor in Electrohydraulic Power Steering Systems 显示文摘 | Jin Hur | 2008 | IEEE Transactions on Industrial Electronics (S0278-0046)2008，55，6： | 1 |
| 12 | Identification of a Novel Role of T Cells in Postnatal Vasculogenesis:Characterization of Endothelial Progenitor Cell Colonies显示文摘 | Jin Hur Han-Mo Yang Chang-Hwan Yoon | 2007 | Circulation2007，116，： | 1 |
| 13 | Microbial transformation of dissolved organic matter from different sources and its influence on disinfection byproduct formation potentials显示文摘 | Jin Hur Mi-Hee Lee Hocheol Song Mark A. Schlatman | 2013 | Environmental Science and Pollution Research2013，，6： | 1 |
| 14 | Synergistic Neovascularization by Mixed Transplantation of Early Endothelial Progenitor Cells and Late Outgro wth Endothelial Cells:The Role of Angiogenic Cytokines and Matrix Metalloprotei nases显示文摘 | Chang-Hwan Yoon Jin Hur Kyung-Woo Park | 2005 | Circulation2005，112，： | 1 |
| 15 | Characterization of two types of endothelial progenitor cells and their different contributions to neovasculogenesis显示文摘 | Jin Hur Chang-Hwan Yoon | 2004 | Arterioscler Thromb Vase Biol2004，24，： | 1 |
| 16 | Performance analysis of a brushless dc motor due to magnetization distribution in a continuous ring magnet显示文摘 | Hur Jin Jung In-Soung Sung Ha-Gyeong | 2003 | Journal of applied physics2003，，10： | 1 |
| 17 | Robotic Versus Laparoscopic Low Anterior Resection of Rectal Cancer: Short-Term Outcome of a Prospective Comparative Study显示文摘 | Seung Hyuk Baik MD Hye Youn Kwon MD Jin Soo Kim MD Hyuk Hur MD Seung Kook Sohn MD Chang Hwan Cho MD Hoguen Kim MD | 2009 | Annals of Surgical Oncology2009，，6： | 1 |
| 18 | Endoscopic stenting is not as effective for palliation of colorectal obstruction in patients with advanced gastric cancer as emergency surgery显示文摘 | Bo Kyung Kim Sung Pil Hong Hyun Mi Heo Jin Young Kim Hyuk Hur Kang Young Lee Jae Hee Cheon Tae Il Kim Won Ho Kim | 2012 | Gastrointestinal Endoscopy2012，，2： | 1 |
| 19 | Oncologic Outcomes After Radical Surgery Following Preoperative Chemoradiotherapy for Locally Advanced Lower Rectal Cancer: Abdominoperineal Resection Versus Sphincter-Preserving Procedure显示文摘 | Jin Soo Kim Hyuk Hur Nam Kyu Kim Young Wan Kim Sun Yeon Cho Jeong Yeon Kim Byung Soh Min Joong Bae Ahn Ki Chang Keum Hoguen Kim Seung Kook Sohn Chang Hwan Cho | 2009 | Annals of Surgical Oncology2009，，5： | 1 |
| 20 | Viseral fat thick-ness measured by ultrasonography can estimate not only visceralobesity but also risks of cardiovascular and metabolic diseases显示文摘 | Soo Kyung Kim Hae Jin Kim Kyu Yeon Hur | 2004 | American Journal of Clinical Nutrition2004，79，59： | 1 |
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