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| 1 | Scutellaria baicalensis in Stroke Management:Nature's Blessing in Traditional Eastern Medicine显示文摘Scutellaria baicalensis Georgi is the most widely used medicinal plant in traditional Eastern medicine,especially in Chinese medicine.The major phytochemicals isolated from S.baicalensis are flavonoids,glycosides and their glucoronides such as baicalin,baicalein,wogonin etc.More than 30 different kinds of flavonoids are isolated from this plant.S.baicalensis and its flavonoids are reported to have several pharmacological activities,which includes anti-allergic,antioxidant,anti apoptic,anti-inflammatory effects and many more.Recently,S.baicalensis and its isolated flavonoids have been studied for their neuroprotective effects,through a variety of in vitro and in vivo models of neurodegenerative diseases,plausibly suggesting that S.baicalensis has salutary effect as a nature's blessing for neuroprotection.In this review,we are focousing on the neuroprotective effects of S.baicalensis and its flavonoids in ischemia or stroke-induced neuronal cell death.We aimed at compiling all the information regarding the neuroprotective effect of S.baicalensis in various experimental models of cerebral ischemia or stroke. | Bhakta Prasad Gaire Sang-Kwan Moon Hocheol Kim | 2014 | Chinese Journal of Integrative Medicine2014，20，9： | 8 |
| 2 | Amomum villosum induces longitudinal bone growth in adolescent female rats显示文摘OBJECTIVE:This study was conducted to evaluate the effect of Amomum villosum on longitudinal bone growth.METHODS:Adolescent female Sprague-Dawley rats were divided into 3 groups and treated for 4 days:control(distilled water,p.o.),recombinant human growth hormone(rhGH;100 μg/kg,s.c.),and A.villosum(500 mg/kg,p.o.) groups.On day 3,tetracycline(20 g/kg,i.p.) was injected for growth plate identification.On days 2,3 and 4,5-bromo-2'-deoxyuridine(BrdU)(50 mg/kg,i.p.) was injected to label proliferating cells.On day 5,tibias were dissected and fixed in 4% paraformaldehyde,dehydrated,and sectioned for immunohistochemistry and histomorphometry.RESULTS:The rate of bone growth in the A.villosum and rhGH groups increased to(410 ± 44) and(389 ± 46) μm/day(P<0.01),respectively,as compared with the control(330.7 ± 34.7) μm/day.The thickness of the growth plates also increased to(591 ± 37) and(598 ± 32) μm,respectively,as compared with the control(524± 89) μm(P<0.001).The number of BrdU-positive cells in the chondrocytes of the A.villosum and rhGH groups was also significantly higher(126±24) and(143±18) cells/mm 2,respectively) than in the control(109 ± 25) mm 2(P<0.05).Insulin-like growth factor-1 and bone morphogenetic protein-2 in the A.villosum and rhGH groups were highly expressed in the growth plate as compared with the control samples,indicating increased bone formation.CONCLUSIONS:A.villosum could be used to treat growth retardation during adolescence. | Sun Haeng Lee Ji Young Kim Hocheol Kim Seul Ki Park Cho Young Kim Sun Yong Chung Gyu Tae Chang | 2012 | Journal of Traditional Chinese Medicine2012，32，3： | 6 |
| 3 | Neuroprotective effects of Fructus Chebulae extracts on experimental models of cerebral ischemia显示文摘OBJECTIVE:To investigate the neuroprotective effects of Fructus Chebulae extract using both in vivo and invitromodels of cerebral ischemia.METHODS:As an in vitro model,oxygen glucose deprivation followed by reoxygenation(OGD-R)and hydrogen peroxide(H2O2)induced cellular damage in rat pheochromocytoma(PC12)cells was used to investigate the neuroprotective effects of extract of Fructus Chebulae.3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay was used to calculate cell survival.For in vivo,occlusion of left middle cerebral artery on rats was carried out as a focal cerebral ischemic model.RESULTS:Fructus Chebulae extract increases the PC12 cell survival against OGD-R and H2O2by 68%and 91.4%respectively.Fructus Chebulae also de-creases the cerebral infarct volume by 39%and extent of hemisphere swelling from 17%in control group to 10%in FructusChebulaetreated group.CONCLUSION:Fructus Chebulae,as a traditional medicine,can rescue the neuronal cell death against ischemia related damage.The possible mechanism for the neuroprotection might be the inhibition of oxidative damages occurring after acute phase of cerebral ischemia. | Bhakta Prasad Gaire Hocheol Kim | 2014 | Journal of Traditional Chinese Medicine2014，34，1： | 2 |
| 4 | Microbial transformation of dissolved organic matter from different sources and its influence on disinfection byproduct formation potentials显示文摘 | Jin Hur Mi-Hee Lee Hocheol Song Mark A. Schlatman | 2013 | Environmental Science and Pollution Research2013，，6： | 1 |
| 5 | Biological reprocessing of mixed office waste (mow) using modified cellulase by production of functional copolymer显示文摘 | Kwinam Park Jongjin Park Hocheol Song Hochul Shin Jinwon Park June-shu Ahn | | 0，，： | 1 |
| 6 | Numericalstudy on the flow noise generation in an automotivemuffler system显示文摘 | HOCHEOL S SEJONG P KYOUNGSUK P | 2007 | SAE International2007，，8： | 1 |
| 7 | The effects of pH, bromide and nitrite on halonitromethane and trihalomethane formation from amino acids and amino sugars显示文摘 | Junhong Shan Jia Hu S. Sule Kaplan-Bekaroglu Hocheol Song Tanju Karanfil | 2011 | Chemosphere2011，，4： | 1 |
| 8 | Investigation into mechanical properties of austempered ductile cast iron (ADI) in accordance with austempering temperature显示文摘 | Kim Yoon-Jun Shin Hocheol Park Hyounsoo | 2008 | Materials Letters2008，62，： | 1 |
| 9 | Halonitromethane formation potentials in drinking waters显示文摘 | Jia Hu Hocheol Song Jesse W. Addison Tanju Karanfil | 2009 | Water Research2009，，1： | 1 |
| 10 | A novel chitosan/clay/magnetite composite for adsorption of Cu(II) and As(V)显示文摘 | Dong-Wan Cho Byong-Hun Jeon Chul-Min Chon Yongje Kim Franklin W. Schwartz Eung-Seok Lee Hocheol Song | 2012 | Chemical Engineering Journal2012，，： | 1 |
| 11 | Regulation of IL- 18 production by IFN- 7 and PGE2 in mouse microglial cells: involvement of NF-κB pathway in the regulatory processes显示文摘 | Kyoungho S Sun YK Hocheol K | 2001 | Immunology Letters2001，77，2001： | 1 |
| 12 | Flavonoid wngonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia显示文摘 | Heasuk Lee Young Ok Kim Hocheol Kim etal | | The FASEB Journal express article0，17，： | 1 |
| 13 | Biological Reprocessing of Mixed Office Waste (MOW) Using Modified Cellulase by Production of Functional Copolymer显示文摘 | KWINAM PARK JONGJIN PARK HOCHEOL SONG | 2002 | Korean J Chem Eng2002，19，2： | 1 |
| 14 | The effects of selected preoxidation strategies on I-THM formation and speciation 显示文摘 | Darryl B Jones Hocheol Song Tanju Karanfil | 2012 | Water Research2012，46，： | 1 |
| 15 | Defluoridation from aqueous solutions by granular ferric hydroxide (GFH)显示文摘 | Eva Kumar Amit Bhatnagar Minkyu Ji Woosik Jung Sang-Hun Lee Sun-Joon Kim Giehyeon Lee Hocheol Song Jae-Young Choi Jung-Seok Yang Byong-Hun Jeon | 2008 | Water Research2008，，2： | 1 |
| 16 | The effects of pH, bromide and nitrite on halonitromethane and trihalomethane formation from amino acids and amino sugars显示文摘 | Junhong Shan Jia Hu S. Sule Kaplan-Bekaroglu Hocheol Song Tanju Karanfil | 2011 | Chemosphere2011，，4： | 1 |
| 17 | Serum ferritin levels predict incident non-alcoholic fatty liver disease in healthy Korean men显示文摘 | Chan-Won Kim Yoosoo Chang Eunju Sung Hocheol Shin Seungho Ryu | 2012 | Metabolism2012，，8： | 1 |
| 18 | Adsorption of nitrate and Cr(VI) by cationic polymer-modified granular activated carbon显示文摘 | Dong-Wan Cho Chul-Min Chon Yongje Kim Byong-Hun Jeon Frank W. Schwartz Eung-Seok Lee Hocheol Song | 2011 | Chemical Engineering Journal2011，，： | 1 |
| 19 | Protective effects of methanol extract of acori graminei rhizome and uneariae ramulus et uncus on ischemia-induced neuronal death and cognitive impairments in the rat显示文摘 | Bombi L YoungKook C Hocheol K | 2003 | Lfie Sciences2003，74，： | 1 |
| 20 | Removal of toxic elements from aqueous environments using nano zero-valent iron-and iron oxide-modified biochar:a review显示文摘Biochar(BC)has gained attention for removal of toxic elements(TEs)from aqueous media;however,pristine biochar often exhibits low adsorption capability.Thus,various modification strategies in BC have been developed to improve its removal capability against TEs.Nanoscale zero-valent iron(nZVI)and iron oxides(FeOx)have been used as sorbents for TE removal.However,these materials are prone to agglomeration and also expensive,which make their usage limited for large-scale applications.The nZVI technical demerits could be resolved by the development of BC-based composite sorbents through the loading of nZVI or FeOx onto BC surface.Nano zero-valent iron modified BC(nZVIBC),FeOx-modified BC(FeOxBC)have attracted attention for their capability in removing pollutants from the aqueous phases.Nonetheless,a potential use of nZVIBC and FeOxBC for TE removal from aqueous environments has not been well-realized or reviewed.As such,this article reviews:(i)the preparation and characterization of nZVIBC and FeOxBC;(ii)the capacity of nZVIBC and FeOxBC for TE retention in line with their physicochemical properties,and(iii)TE removal mechanisms by nZVIBC and FeOxBC.Adopting nZVI and FeOx in BC increases its sporptive capability of TEs due to surface modifications in morphology,functional groups,and elemental composition.The combined effects of BC and nZVI,FeOx or Fe salts on the sorption of TEs are complex because they are very specific to TEs.This review identified significant opportunities for research and technol-ogy advancement of nZVIBC and FeOxBC as novel and effective sorbents for the remediation of TEs contaminated water. | Sabry M.Shaheen Ahmed Mosa Natasha Hamada Abdelrahman Nabeel Khan Niazi Vasileios Antoniadis Muhammad Shahid Hocheol Song Eilhann E.Kwon Jörg Rinklebe | 2022 | Biochar2022，4，1： | 1 |
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