|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A Comparative Study on the Performance of Typical Types of Bionic Groove Dry Gas Seal based on Bird Wing显示文摘 | Jinbo Jiang Xudong Peng Jiyun Li Yuan Chen | 2016 | Journal of Bionic Engineering2016，13，2： | 15 |
| 2 | Mitochondrial calcium uniporter protein MCU is involved in oxidative stress-induced cell death显示文摘Mitochondrial 钙 uniporter (MCU ) 是在在真核细胞的房间的 mitochondrial 的保存 Ca 2+ transporter。然而,在氧化导致压力的房间死亡的 MCU 蛋白质的角色仍然保持不清楚。这里,我们证明宫外地表示的 MCU 是在局部性的 mitochondrial HeLa 和主要小脑的小粒神经原(CGN ) 。内长的 MCU 减少 mitochondrial Ca 2+ 举起追随者组织安刺激击倒并且稀释氧化应力在 HeLa 房间和 CGN 导致的房间死亡。我们也发现 MCU 与 VDAC1 交往并且调停在 CGN 的 VDAC1 导致 overexpression 的房间死亡。这发现证明那 MCU-VDAC1 建筑群调整 mitochondrial Ca 2+ 举起和氧化导致压力的 apoptosis,它可能表示为氧化应力的治疗学的目标联系了疾病。 | Yajin Liao Yumin Hao Hong Chen Qing He Zengqiang Yuan Jinbo Cheng | 2015 | Protein & Cell2015，6，6： | 12 |
| 3 | Gas Film Disturbance Characteristics Analysis of High-Speed and High-Pressure Dry Gas Seal显示文摘The dry gas seal(DGS) has been widely used in high parameters centrifugal compressor, but the intense vibrations of shafting,especially in high-speed condition, usually result in DGS's failure. So the DGS's ability of resisting outside interference has become a determining factor of the further development of centrifugal compressor. However, the systematic researches of which about gas film disturbance characteristics of high parameters DGS are very little. In order to study gas film disturbance characteristics of high-speed and high-pressure spiral groove dry gas seal(S-DGS) with a flexibly mounted stator, rotor axial runout and misalignment are taken into consideration, and the finite difference method and analytical method are used to analyze the influence of gas film thickness disturbance on sealing performance parameters, what's more, the effects of many key factors on gas film thickness disturbance are systematically investigated. The results show that, when sealed pressure is 10.1MPa and seal face average linear velocity is 107.3 m/s, gas film thickness disturbance has a significant effect on leakage rate, but has relatively litter effect on open force; Excessively large excitation amplitude or excessively high excitation frequency can lead to severe gas film thickness disturbance; And it is beneficial to assure a smaller gas film thickness disturbance when the stator material density is between 3.1 g/cm^3 to 8.4 g/cm^3; Ensuring sealing performance while minimizing support axial stiffness and support axial damping can help to improve dynamic tracking property of dry gas seal. The proposed research provides the instruction to optimize dynamic tracking property of the DGS. | CHEN Yuan JIANG Jinbo PENG Xudong | 2016 | Chinese Journal of Mechanical Engineering2016，29，6： | 11 |
| 4 | PKM2 coordinates glycolysis with mitochondrial fusion and oxidative phosphorylation显示文摘A change in the metabolic flux of glucose from mitochondrial oxidative phosphorylation (OXPHOS) to aerobic glycolysis is regarded as one hallmark of cancer. However, the mechanisms underlying the metabolic switch between aerobic glycolysis and OXPHOS are unclear. Here we show that the M2 isoform of pyruvate kinase (PKM2), one of the rate-limiting enzymes in glycolysis, interacts with mitofusin 2 (MFN2), a key regulator of mitochondrial fusion, to promote mitochondrial fusion and OXPHOS, and attenuate glycolysis. mTOR increases the PKM2:MFN2 interaction by phosphorylating MFN2 and thereby modulates the effect of PKM2: MFN2 on glycolysis, mitochondrial fusion and OXPHOS. Thus, an mTOR-MFN2-PKM2 signaling axis couples glycolysis and OXPHOS to modulate cancer cell growth. | Tong Li Jinbo Han Liangjie Jia Xiao Hu Liqun Chen Yiguo Wang | 2019 | Protein & Cell2019，10，8： | 10 |
| 5 | New double Wronskian solutions of the AKNS equation显示文摘Soliton solutions, rational solutions, Matveev solutions, complexitons and interaction solutions of the AKNS equation are derived through a matrix method for constructing double Wronskian entries. The latter three solutions are novel. Moreover, rational solutions of the nonlinear Schrodinger equation are obtained by reduction. | CHEN DenYuan ZHANG DaJun BI JinBo | 2008 | Science China Mathematics2008，51，1： | 8 |
| 6 | A preliminary study of the failure mechanisms of cascading landslide dams显示文摘Landslide dams commonly form when mass earth or rock movements reach a river channel and cause a complete or partial blockage of the channel.Intense rainfalls can induce upstream flows along a sloping channel that significantly affect downstream landslide dams.If a series of landslide dams are collapsed by incoming mountain torrents(induced by intense rainfall),large debris flows can form in a very short period.Furthermore,the failure of these dams can amplify the magnitude and scale of debris flows in the flow direction.The catastrophic debris flows that occurred in Zhouqu County,China on 8 August 2010 were caused by intense rainfall and the upstream cascading failure of landslide dams along the gullies.Incorporating the role of outburst floods associated with the complete or partial failure of landslide dams is an interesting problem usually beyond the scope of analysis because of the inherent modeling complexity.To understand the cascading failure modes of a series of landslide dams,and the dynamic effect these failures have on the enlargement of debris flow scales,experimental tests are conducted in sloping channels mimicking field conditions,with the modeled landslide dams distributed along a sloping channel and crushed by different upstream flows.The failure modes of three different cascades of landslide dams fully or partially blocking a channel river are parametrically studied.This study illustrates that upstream flows can induce a cascading failure of the landslide dams along a channel.Overtopping is the primary failure mechanism,while piping and erosion can also induce failures for different constructed landslide dams.A cascading failure of landslide dams causes a gradually increasing flow velocity and discharge of the front flow,resulting in an increase in both diameter and percentage of the entrained coarse particles.Furthermore,large landslide blockages can act to enhance the efficiency of river incision,or conversely to induce aggradation of fluvial sediments,depending on the blockage factor of the landslide dams and upstream discharge. | Gordon G.D Peng Cui Xinghua Zhu Jinbo Tang Huayong Chen Qicheng Sun | 2015 | International Journal of Sediment Research2015，30，3： | 8 |
| 7 | A genome-wide analysis of SWEET gene family in cotton and their expressions under different stresses显示文摘Background: The SWEET(Sugars will eventually be exported transporters) gene family plays multiple roles in plant physiological activities and development process. It participates in reproductive development and in the process of sugar transport and absorption, plant senescence and stress responses and plant-pathogen interaction. However,thecomprehensive analysis of SWEET genes has not been reported in cotton.Results: In this study, we identified 22, 31, 55 and 60 SWEET genes from the sequenced genomes of Gossypium arboreum, G. raimondii, G. hirsutum and G. barbadense, respectively. Phylogenetic tree analysis showed that the SWEET genes could be divided into four groups, which were further classified into 14 sub-clades. Further analysis of chromosomal location, synteny analysis and gene duplication suggested that the orthologs showed a good collinearity and segmental duplication events played a crucial role in the expansion of the family in cotton. Specific MtN3_slv domains were highly conserved between Arobidopsis and cotton by exon-intron organization and motif analysis. In addition, the expression pattern in different tissues indicated that the duplicated genes in cotton might have acquired new functions as a result of sub-functionalization or neo-funtionalization. The expression pattern of SWEET genes showed that the different genes were induced by diverse stresses. The identification and functional analysis of SWEET genes in cotton may provide more candidate genes for genetic modification.Conclusion: SWEET genes were classified into four clades in cotton. The expression patterns suggested that the duplicated genes might have experienced a functional divergence. This work provides insights into the evolution of SWEET genes and more candidates for specific genetic modification, which will be useful in future research. | ZHAO Lanjie YAO Jinbo CHEN Wei LI Yan L Youjun GUO Yan WANG Junyi YUAN Li LIU Ziyang ZHANG Yongshan | 2018 | Journal of Cotton Research2018，1，2： | 6 |
| 8 | LncRNA-MALAT1 mediates cisplatin resistance via miR-101-3p/VEGF-C pathway in bladder cancer显示文摘The mitotically associated lncRNA(MANCR)participates in breast cancer cell proliferation,while its involvement in other cancers is still unknown.In this study,we therefore studied the role of MANCR in mantle cell lymphoma(MCL).We found that serum MANCR and Runt-related transcription factor 2(RUNX2)were upregulated in MCL patients when compared with those in healthy controls.A positive correlation between serum MANCR and RUNX2 was found in MCL patients but not in controls.Upregulation of serum MANCR distinguished MCL patients from controls.MANCR overexpression promoted RUNX2 expression in MCL cells,while RUNX2 overexpression failed to significantly change the expression levels of MANCR.MANCR overexpression promoted the proliferation of MCL cells,while MANCR silencing inhibited the proliferation of MCL cells.In addition,RUNX2 overexpression attenuated the inhibitory effects of MANCR silencing on cell proliferation.However,MANCR overexpression and silencing had no significant effects on cell migration and invasion.Further bioinformatics analysis showed that MANCR may sponge miR-218 to upregulate RUNX2.Therefore,we conclude that downregulation of MANCR may inhibit cancer cell proliferation in MCL possibly by interacting with RUNX2. | Peihua Liu Xiaozhou Li Yu Cui Jinbo Chen Chao Li Qiaqia Li Huihuang Li Xiangyang Zhang Xiongbing Zu | 2019 | Acta Biochimica et Biophysica Sinica2019，51，11： | 6 |
| 9 | Reemergent Cases of COVID-19--Dalian City,Liaoning Province,China,July 22,2020显示文摘From July 22-23,3 local COVID-19 cases were reported in Dalian City,Liaoning Province,China.All 3 patients reported that they did not leave Dalian 14 days before the onset of disease and had no COVID-19 case contact history and no foreign personnel contact history.Epidemiological investigation,medical isolation,and nucleic acid detection was immediately carried out in Dalian,and 12 asymptomatic infections were detected in close contacts of Patient 1.Because asymptomatic infections made up a large proportion of total infections,the outbreak was likely observed in the beginning stages. | Xiang Zhao Lingling Mao Jianqun Zhang Yong Zhang Yang Song Zhijian Bo Hong Wang Ji Wang Cao Chen Jinbo Xiao Tianjiao Ji Qian Yang Wenbo Xu Dayan Wang Wenqing Yao | 2020 | China CDC weekly2020，2，34： | 5 |
| 10 | The Seasonal Variation of Large Volume Airgun Signals in Hutubi,Xinjiang显示文摘In order to study the seasonal variation of large volume airgun signals in Hutubi,Xinjiang,we analyzed 2,936 signals of airgun source excitations during 2015-2016 received by a seismograph on the bank of the excitation pool.Firstly,the RMS value of the signal amplitude and the daily average temperature were compared after linearly superimposing the signal in days,to analyze the influence of the surface ice cover on the excitation energy release of the airgun source.The result shows that the ice cover will reduce the excitation energy,and the thicker the ice cover is,the more obvious the excitation energy reduces.Secondly,the time-frequency analysis method was used to analyze the influence of the surface ice cover on the signal frequency.It is concluded that the existence of the ice cover has little effect on the signal frequency,but it will affect the intensity of the signal around 4 Hz between 1-2 s after excitation.The cause of these phenomena is that the ice cover affects the bubble oscillation,which in turn affects the energy conversion.The study shows that when using the cross-correlation delay method to calculate the wave velocity,the signals can be divided into two periods according to the daily average temperature:with or without ice cover on the upper surface of the excitation pool.This can help eliminate the influence of the source variation and improve the accuracy of the monitoring results. | SU Jinbo WANG Qiong ZHANG Wenxiu WEI Yunyun CHEN Hao WANG Haitao | 2019 | Earthquake Research in China2019，33，2： | 5 |
| 11 | WSe2 2D p-type semiconductor-based electronic devices for information technology:Design,preparation,and applications显示文摘The pioneering exfoliation of monolayer tungsten diselenide has greatly inspired researchers toward semiconducting applications.WSe2 belongs to a family of transition-metal dichalcogenides.Similar to graphene,WSe2 and analogous dichalcogenides have layered structures with weak van der Waals interactions between two adjacent layers.First,the readers are presented with the fundamentals of WSe2,such as types,morphologies,and properties.Here,we report the characterization principles and practices such as microscopy,spectroscopy,and diffraction.Second,the methods for obtaining high-quality WSe2,such as exfoliation,hydrothermal and chemical vapor deposition,are briefly listed.With advantages of light weight,flexibility,and high quantum efficiency,2D materials may have a niche in optoelectronics as building blocks in p-n junctions.Therefore,we introduce a state-of-the-art demonstration of heterostructure devices employing the p-type WSe2 semiconductor.The device architectures include field-effect transistors,photodetectors,gas sensors,and photovoltaic solar cells.Due to its unique electronic,optical,and energy band properties,WSe2 has been increasingly investigated due to the conductivity of the p-type charge carrier upon palladium contact.Eventually,the dynamic research on WSe2 and van der Waals heterostructures is summarized to arouse the passion of the 2D research community. | Qilin Cheng Jinbo Pang Dehui Sun Jingang Wang Shu Zhang Fan Liu Yuke Chen Ruiqi Yang Na Liang Xiheng Lu Yanchen Ji Jian Wang Congcong Zhang Yuanhua Sang Hong Liu Weijia Zhou | 2020 | InfoMat2020，2，4： | 5 |
| 12 | Fast-Suppressor Screening for New Components in Protein Trafficking,Organelle Biogenesis and Silencing Pathway in Arabidopsis thaliana Using DEX-Inducible FREE1-RNAi Plants显示文摘Membrane trafficking is essential for plant growth and responses to external signals.The plant unique FYVE domain-containing protein FREE1 is a component of the ESCRT complex(endosomal sorting complex required for transport).FREE1 plays multiple roles in regulating protein trafficking and organelle biogenesis including the formation of intraluminal vesicles of multivesicular body(MVB),vacuolar protein transport and vacuole biogenesis,and autophagic degradation.FREE1 knockout plants show defective MVB formation,abnormal vacuolar transport,fragmented vacuoles,accumulated autophagosomes,and seedling lethality.To further uncover the underlying mechanisms of FREE1 function in plants,we performed a forward genetic screen for mutants that suppressed the seedling lethal phenotype of FREE1-RNAi transgenic plants.The obtained mutants are termed as suppressors of free1(sof).To date,229 putative sof mutants have been identified.Barely detecting of FREE1 protein with M3plants further identified 84 FREE1-related suppressors.Also145 mutants showing no reduction of FREE1 protein were termed as RNAi-related mutants.Through next-generation sequencing(NGS)of bulked DNA from F2mapping population of two RNAi-related sof mutants,FREE1-RNAi T-DNA inserted on chromosome 1 was identified and the causal mutation of putative sof mutant is being identified similarly.These FREE1-and RNAi-related sof mutants will be useful tools and resources for illustrating the underlying mechanisms of FREE1 function in intracellular trafficking and organelle biogenesis,as well as for uncovering the new components involved in the regulation of silencing pathways in plants. | Qiong Zhao Caiji Gao PoShing Lee Lin Liu Shaofang Li Tangjin Hu Jinbo Shen Shuying Pan Hao Ye Yunru Chen Wenhan Cao Yong Cui Peng Zeng Sheng Yu Yangbin Gao Liang Chen Beixin Mo Xin Liu Shi Xiao Yunde Zhao Silin Zhong Xuemei Chen Liwen Jiang | 2015 | Journal of Genetics and Genomics2015，42，6： | 4 |
| 13 | Research on Large Volume Airgun Source Signal Reception in Hutubi, Xinjiang Using Seismic Network Data显示文摘We used data from the Xinjiang Digital Seismic Network and PSD( Power Spectral Density) method to perform noise level assessment for six stations. We calculated the median of the power spectral density to evaluate the noise level of different stations. After the comparison of the power spectral density of different stations and the airgun signal recognition,we found that noise level of stations with recognizable airgun source signals is lower than that of stations without recognizable signals. The largest difference of the power spectral density is 40 d B,and the smallest is 15 d B. Finally,we found that the failure to recognize the signal of airgun sources at some stations is due to the noise level. | Su Jinbo Wang Qiong Wang Haitao Shi Yongjun Chen Xiangjun Feng Lei Chen Hao Zhang Wenxiu | 2016 | Earthquake Research in China2016，30，3： | 4 |
| 14 | Genomic characterization of SARS-CoV-2 identified in a reemerging COVID-19 outbreak in Beijing's Xinfadi market in 2020显示文摘After 56 days without coronavirus disease 2019(COVID-19)cases,reemergent cases were reported in Beijing,China on June 11,2020.Here,we report the genetic characteristics of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)sequenced from the clinical specimens of 4 human cases and 2 environmental samples.The nucleotide similarity among six SARS-CoV-2 genomes ranged from 99.98%to 99.99%.Compared with the reference strain of SARS-CoV-2(GenBank No.NC_045512),all six genome sequences shared the same substitutions at nt241(C→T),nt3037(C→T),nt14408(C→T),nt23403(A→G),nt28881(G→A),nt28882(G→A),and nt28883(G→C),which are the characteristic nucleotide substitutions of L-lineage European branch I.This was also proved by themaximum likelihood phylogenetic tree based on the full-length genome of SARS-CoV-2.They also have a unique shared nucleotide substitution,nt6026(C→T),which is the characteristic nucleotide substitution of SARS-CoV-2 in Beijing's Xinfadi outbreak.It is noteworthy that there is an amino acid D614Gmutation caused by nt23403 substitution in all six genomes,which may enhance the virus's infectivity in humans and help it become the leading strain of the virus to spread around the world today.It is necessary to continuously monitor the genetic variation of SARS-CoV-2,focusing on the influence of key mutation sites of SARS-CoV-2 on viral transmission,clinical manifestations,severity,and course of disease. | Yong Zhang Yang Pan Xiang Zhao Weifeng Shi Zhixiao Chen Sheng Zhang Peipei Liu Jinbo Xiao Wenjie Tan Dayan Wang William J.Liu Wenbo Xu Quanyi Wang Guizhen Wu | 2020 | Biosafety and Health2020，2，4： | 3 |
| 15 | Fasting-induced hormonal regulation of lysosomal function显示文摘 | Chen, Liqun Wang, Ke Long, Aijun Jia, Liangjie Zhang, Yuanyuan Deng, Haiteng Li, Yu Han, Jinbo Wang, Yiguo | 2017 | Cell Research2017，27，6： | 3 |
| 16 | Path,feedrate and trajectory planning for free-form surface machining:A state-of-the-art review显示文摘Nowadays,free-form surfaces have been widely used in various industrial fields.They are usually machined by CNC machine tools,but recently have also begun to be manufactured by industrial robotic arm manipulators,thanks to low cost,large operation reaching space and high machining flexibility of robot.So far,various methodologies have been proposed to improve efficiency and quality of free-form surface machining,thus this paper aims at providing a state-ofthe-art review on research advances in free-form surface machining.In this review,tool path generation,feedrate scheduling in Cartesian space and trajectory planning in joint space are focused for both CNC machining and robot machining,and their research statues,existing difficulties and key issues are discussed in detail.Finally,the feasible routes,breakthrough points and future development trend are also expounded. | Yuwen SUN Jinjie JIA Jinting XU Mansen CHEN Jinbo NIU | 2022 | Chinese Journal of Aeronautics2022，35，8： | 3 |
| 17 | Identification of Histoplasma causing an unexplained disease cluster in Matthews Ridge, Guyana显示文摘Here,we report the identification of Histoplasma causing an unexplained disease cluster in Matthews Ridge,Guyana.In March 2019,14 employees of Chongqing Bosai Mining Company,China,working in a manganese mining of Guyana,had unexplained fever,and two of them died.We obtained lung and brain tissues as well as the blood samples from the two deceased cases(patient No.1 and 2),and bronchoscopy lavages and cerebrospinal fluid samples from one severe case(patient No.3),respectively.All samples were tested by pathological examination,high-throughput sequencing,and real-time PCR.Pathological detection showed the presence of spore-like structures in the lung tissue of patient No.1,indicating a fungal infection in this patient.Nanopore sequencing identified the existing of H.capsulatum in the lung tissue sample within 13 h.Next-generation sequencing identified specific fragments of H.capsulatum in all of the samples tested(lung,brain and blood serum from the deceased cases,and plasma from the severe case).Real-time PCR assays did not reveal any viral infection related to transmission from bat feces.We conclude that H.capsulatum was the causative pathogen of this disease cluster based on epidemiologic,clinical,pathological and nucleic acid evidence. | Ji Wang Weimin Zhou Hua Ling Xiaoping Dong Yi Zhang Jiandong Li Yong Zhang Jingdong Song William J.Liu Yang Li Ruiqing Zhang Wei Zhen Kun Cai Shuangli Zhu Dongyan Wang Jinbo Xiao Yigang Tong Wenli Liu Lihua Song Wei Wu Yang Liu Xiang Zhao Ruihuan Wang Sheng Ye Jing Wang Roujian Lu Baoying Huang Fei Ye Wenwen Lei Rongbao Gao Qi Shi Cao Chen Jun Han Wenbo Xu George F.Gao Xuejun Ma Guizhen Wu | 2019 | Biosafety and Health2019，1，3： | 3 |
| 18 | CAS FGOALS-g3 Model Datasets for the CMIP6 Scenario Model Intercomparison Project(ScenarioMIP)显示文摘This paper describes the datasets from the Scenario Model Intercomparison Project(ScenarioMIP)simulation experiments run with the Chinese Academy of Sciences Flexible Global Ocean–Atmosphere–Land System Model,GridPoint version 3(CAS FGOALS-g3).FGOALS-g3 is driven by eight shared socioeconomic pathways(SSPs)with different sets of future emission,concentration,and land-use scenarios.All Tier 1 and 2 experiments were carried out and were initialized using historical runs.A branch run method was used for the ensemble simulations.Model outputs were three-hourly,six-hourly,daily,and/or monthly mean values for the primary variables of the four component models.An evaluation and analysis of the simulations is also presented.The present results are expected to aid research into future climate change and socio-economic development. | Ye PU Hongbo LIU Ruojing YAN Hao YANG Kun XIA Yiyuan LI Li DONG Lijuan LI He WANG Yan NIE Mirong SONG Jinbo XIE Shuwen ZHAO Kangjun CHEN Bin WANG Jianghao LI and Ling ZUO | 2020 | Advances in Atmospheric Sciences2020，37，10： | 3 |
| 19 | Catalytic decomposition of ethyl acetate over La-modified Cu-Mn oxide supported on honeycomb ceramic显示文摘The La-modified Cu-Mn spinel oxide was successfully coated onto honeycomb ceramic by a washcoating method for complete catalytic decomposition of ethyl acetate.The La-modified Cu-Mn oxides were characterized by X-ray diffraction,X-ray fluorescence,H_(2)-temperature programmed reduction,Brunauer-Emmett-Teller method,field-emission scanning electron microscopy and high-resolution transmission electron microscopy.The effects of different precipitants and rare earth doping on the structure and catalytic performance of the catalysts were investigated.The results show that the CuMn_(2)O_(4) spinel with(NH_(4))_(2)CO_(3) as a precipitant can form a larger specific surface area and a suitable pore size,which is beneficial to the absorption of ethyl acetate.Although the rare earth doping does not significantly change the crystal phase structure of the catalyst,it improves its reducibility and lowers the temperature of the catalytic decomposition.With respect to the catalytic decomposition of ethyl acetate,the rare earth-modified Cu-Mn oxide supported on honeycomb ceramic shows excellent catalytic performance with 100% conversion under the conditions of 239℃,space velocity of 12500 h^(-1) and 1000 ppm.And the ethyl acetate removal rate is still 100% after 1440 min of continuous reaction. | Rui Xiao Ruixiang Qin Chunxue Zhang Shan Chen Jinbo Wang | 2021 | Journal of Rare Earths2021，39，7： | 2 |
| 20 | CRTC2 modulates hepatic SREBPlc cleavage by controlling Insig2a expression during fasting显示文摘 | Yuanyuan Zhang Yi Liu Liqun Chen Yiguo Wang Jinbo Han | 2018 | Protein & Cell2018，9，8： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员