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| 1 | Biomaterial–Related Cell Microenvironment in Tissue Engineering and Regenerative Medicine显示文摘An appropriate cell microenvironment is key to tissue engineering and regenerative medicine.Revealing the factors that influence the cell microenvironment is a fundamental research topic in the fields of cell biology,biomaterials,tissue engineering,and regenerative medicine.The cell microenvironment consists of not only its surrounding cells and soluble factors,but also its extracellular matrix(ECM)or nearby external biomaterials in tissue engineering and regeneration.This review focuses on six aspects of bioma-terial-related cell microenvironments:①chemical composition of materials,②material dimensions and architecture,③material-controlled cell geometry,④effects of material charges on cells,⑤matrix stiff-ness and biomechanical microenvironment,and⑥surface modification of materials.The present chal-lenges in tissue engineering are also mentioned,and eight perspectives are predicted. | Jingming Gao Xiaoye Yu Xinlei Wang Yingning He Jiandong Ding | 2022 | Engineering2022,8,6: | 3 |
| 2 | A CONSIDERATION OF DIFFERENT INDIVIDUAL FACTORS IN CLASSROOM LANGUAGE TEACHING显示文摘Students’ individual differences pose a challenge to language teachers and influence the way in which a foreign language is learned. We are therefore invited to consider the role of our students’ personalities,motivation and cognitive styles in the language classroom. LANGUAGE teaching would be much easier if all students were alike. The number of instructional decisions would be greatly reduced; teaching methods would be rather simpler; lesson designs would not have to be modified; teachers would not have to consider alternative procedures; teacher-student | Gao Zhiguo Jingming Vocational and Technical Education Centre, Gansu Province | 1998 | Chinese Journal of Applied Linguistics1998,21,1: | 2 |
| 3 | Magnetic resonance imaging for non-invasive clinical evaluation of normal and regenerated cartilage显示文摘With the development of tissue engineering and regenerative medicine,it is much desired to establish bioimaging techniques to monitor the real-time regeneration efficacy in vivo in a non-invasive way.Herein,we tried magnetic resonance imaging(MRI)to evaluate knee cartilage regeneration after implanting a biomaterial scaffold seeded with chondrocytes,namely,matrix-induced autologous chondrocyte implantation(MACI).After summary of the T2 mapping and the T1-related delayed gadolinium-enhanced MRI imaging of cartilage(dGEMRIC)in vitro and in vivo in the literature,these two MRI techniques were tried clinically.In this study,18 patients were followed up for 1 year.It was found that there was a significant difference between the regeneration site and the neighboring normal site(control),and the difference gradually diminished with regeneration time up to 1 year according to both the quantitative T1 and T2 MRI methods.We further established the correlation between the quantitative evaluation of MRI and the clinical Lysholm scores for the first time.Hence,the MRI technique was confirmed to be a feasible semiquantitative yet non-invasive way to evaluate the in vivo regeneration of knee articular cartilage. | Xian Xu Jingming Gao Shuyun Liu Liang Chen Min Chen Xiaoye Yu Ning Ma Jun Zhang Xiaobin Chen Lisen Zhong Lin Yu Liming Xu Quanyi Guo Jiandong Ding | 2021 | Regenerative Biomaterials2021,8,5: | 2 |
| 4 | Induction of priming by cold stress via inducible volatile cues in neighboring tea plants^FA显示文摘Plants have evolved sophisticated defense mechanisms to overcome their sessile nature.However,if and how volatiles from cold‐stressed plants can trigger interplant communication is still unknown.Here,we provide the first evidence for interplant communication via inducible volatiles in cold stress.The volatiles,including nerolidol,geraniol,linalool,and methyl salicylate,emitted from cold‐stressed tea plants play key role(s)in priming cold tolerance of their neighbors via a C‐repeatbinding factors‐dependent pathway.The knowledge will help us to understand how plants respond to volatile cues in cold stress and agricultural ecosystems. | Mingyue Zhao Lu Wang Jingming Wang Jieyang Jin Na Zhang Lei Lei Ting Gao Tingting Jing Shangrui Zhang Yi Wu Bin Wu Yunqing Hu Xiaochun Wan Wilfried Schwab Chuankui Song | 2020 | Journal of Integrative Plant Biology2020,62,10: | 2 |
| 5 | Promoter and coding sequence diversity of CsCCD1 may contribute to the differential accumulation of floralβ-ionone in fresh tea leaves显示文摘The carotenoid-derived volatileβ-ionone makes an important contribution to tea fragrance.Here,we qualitatively and quantitatively analysed 15 carotenoids in tea leaves of 13 cultivars by UHPLC-APCI-MS/MS.The 13 cultivars were divided into two groups by PCA(Principal Component Analysis)clustering analysis of their carotenoid content,and OPLS-DA(Orthogonal projections to latent structures)indicated that the levels ofβ-carotene(VIP=2.89)and lutein(VIP=2.30)were responsible for much of the variation between the two groups.Interestingly,theβ-carotene toβ-ionone conversion rates in Group 1 were higher than in Group 2,while theβ-carotene content was significantly lower in Group 1 than in Group 2.Theβ-ionone content was significantly higher in Group 1.Pearson Correlation Coefficient calculation between the transcription level of candidate genes(CsCCD1 and CsCCD4)and the accumulation ofβ-ionone indicated that CsCCD1 may involve in the formation ofβ-ionone in 13 cultivars.Prokaryotic expression and in vitro enzyme activity assays showed that‘Chuanhuang 1’had an amino acid mutation in carotenoid cleavage dioxygenases 1(CsCCD1)compared with‘Shuchazao’,resulting in a significantly higherβ-ionone content in‘Chuanhuang 1’.Sequence analysis showed that‘Chuanhuang 1’and‘Huangdan’had different CsCCD1 promoter sequences,leading to significantly higher CsCCD1 expression andβ-ionone accumulation in‘Chuanhuang 1’.These results indicated that the promoter and coding sequence diversity of CsCCD1 might contribute to the differential accumulation ofβ-ionone in different tea cultivars. | Jingming Wang Mingyue Zhao Ting Gao Yingying Feng Feiquan Wang Yuting Pan Jieyang Jin Tingting Jing Mengqian Lu Mengting Zhang Danyang Guo Xiaochun Wan Wilfried Schwab Chuankui Song | 2023 | Horticultural Plant Journal2023,9,4: | 1 |
| 6 | Amplification of early drought responses caused by volatile cues emitted from neighboring tea plants显示文摘Plants have developed sophisticated mechanisms to survive in dynamic environments.Plants can communicate via volatile organic compounds(VOCs)to warn neighboring plants of threats.In most cases,VOCs act as positive regulators of plant defense.However,the communication and role of volatiles in response to drought stress are poorly understood.Here,we showed that tea plants release numerous VOCs.Among them,methyl salicylate(MeSA),benzyl alcohol,and phenethyl alcohol markedly increased under drought stress.Interestingly,further experiments revealed that drought-induced MeSA lowered the abscisic acid(ABA)content in neighboring plants by reducing 9-cis-epoxycarotenoid dioxygenase(NCED)gene expression,resulting in inhibition of stomatal closure and ultimately decreasing early drought tolerance in neighboring plants.Exogenous application of ABA reduced the wilting of tea plants caused by MeSA exposure.Exposure of Nicotiana benthamiana to MeSA also led to severe wilting,indicating that the ability of drought-induced MeSA to reduce early drought tolerance in neighboring plants may be conserved in other plant species.Taken together,these results provide evidence that drought-induced volatiles can reduce early drought tolerance in neighboring plants and lay a novel theoretical foundation for optimizing plant density and spacing. | Jieyang Jin Mingyue Zhao Ting Gao Tingting Jing Na Zhang Jingming Wang Xianchen Zhang Jin Huang Wilfried Schwab Chuankui Song | 2021 | Horticulture Research2021,8,1: | 1 |
| 7 | Correction: Amplification of early drought responses caused by volatile cues emitted from neighboring tea plants显示文摘After the publication of this article 1,the authors became aware that the word of“tea”was not mentioned in the title.To make the title clear and complete,the word‘tea’is added to the title. | Jieyang Jin Mingyue Zhao Ting Gao Tingting Jing Na Zhang Jingming Wang Xianchen Zhang Jin Huang Wilfried Schwab Chuankui Song | 2021 | Horticulture Research2021,8,1: | 1 |
| 8 | A novel compact double pulse forming lines显示文摘 | Yang Jianhua Gao Jingming Shu Ting | 2013 | Review of Scientific Instruments2013,84,06: | 1 |
| 9 | ‘Invisible’ orthodontics by polymeric ‘clear’ aligners molded on 3D-printed personalized dental models显示文摘The malalignment of teeth is treated classically by metal braces with alloy wires,which has an unfavorable influence on the patients appearance during the treatment.With the development of digitization,computer simulation and three-dimensional(3D)printing technology,herein,a modern treatment was tried using clear polymeric aligners,which were fabricated by molding polyurethane films via thermoforming on the 3D-printed personalized dental models.The key parameters of photocurable 3D printing of dental models and the mechanical properties of the clear aligner film material were examined.The precision of a 3D-printed dental model mainly relied on characteristics of photocurable resin,the resolution of light source and the exposure condition,which determined the eventual shape of the molded clear aligner and thus the orthodontic treatment efficacy.The biocompatibility of the polyurethane filmmaterial was confirmed through cytotoxicity and hemolysis tests in vitro.Following a series of 3D-printed personalized dental models and finite element analysis to predict and plan the fabrication and orthodontic processes,corresponding clear aligners were fabricated and applied in animal experiments,which proved the efficacy and biocompatibility in vivo.Clinical treatments of 120 orthodontic cases were finally carried out with success,which highlights the advantage of the clear aligners as an esthetic,compatible and efficient appliance. | Xiaoye Yu Guanghui Li Yikan Zheng Jingming Gao Ye Fu Qunsong Wang Lei Huang Xiaogang Pan Jiandong Ding | 2022 | Regenerative Biomaterials2022,9,1: | 0 |
| 10 | Balancing QoE and Fairness of Heterogeneous Traffics Based on Equivalent Rate Scaling显示文摘With great increase of mobile service in recent years,high quality of experience(QoE) is becoming a comprehensive and major goal for service provider.To unify evaluations of different services,mean opinion score(MOS) as a subjective assessment is usually adopted for accurate and convincing reflection of user perceived quality.In this paper,we consider the effect of the burst transmission of best effort(BE) traffic on the uses with real time video traffic in the same cell.We extend the rate scaling process which was initially used to shape burstiness of BE users as interference to handle the scenario that BE users act as resource competitors with video users.A power reallocation strategy between the two types of users is presented and an algorithm further improving the fairness of BE users is proposed.The simulation results demonstrate that the proposed algorithm can not only promote the QoE of both types of users,but also guarantee the fairness among users. | GAO Qiang FEI Zesong LI Na XING Chengwen KUANG Jingming | 2015 | China Communications2015,12,1: | 0 |
| 11 | Revealing alkali metal ions transport mechanism in the atomic channels of Au@a-MnO_(2)显示文摘Understanding alkali metal ions’(e.g.,Li^(+)/Na^(+)/K^(+))transport mechanism is challenging but critical to improving the performance of alkali metal batteries.Herein using a-MnO_(2)nanowires as cathodes,the transport kinetics of Li^(+)/Na^(+)/K^(+)in the 2×2 channels of a-MnO_(2)with a growth direction of[001]is revealed.We show that ion radius plays a decisive role in determining the ion transport and electrochemistry.Regardless of the ion radii,Li^(+)/Na^(+)/K^(+)can all go through the 2×2 channels of a-MnO_(2),generating large stress and causing channel merging or opening.However,smaller ions such as Li^(+)and Na^(+)cannot only transport along the[001]direction but also migrate along the<110>direction to the nanowire surface;for large ion such as K^(+),diffusion along the<110>direction is prohibited.The different ion transport behavior has grand consequences in the electrochemistry of metal oxygen batteries(MOBs).For Li-O_(2)battery,Li^(+)transports uniformly to the nanowire surface,forming a uniform layer of oxide;Na^(+)also transports to the nanowire surface but may be clogged locally due to its larger radius,therefore sporadic pearl-like oxides form on the nanowire surface;K^(+)cannot transport to the nanowire surface due to its large radius,instead,it breaks the nanowire locally,causing local deposition of potassium oxides.The study provides atomic scale understanding of the alkali metal ion transport mechanism which may be harnessed to improve the performance of MOBs. | Jingzhao Chen Yong Su Hongjun Ye Yushu Tang Jitong Yan Zhiying Gao Dingding Zhu Jingming Yao Xuedong Zhang Tingting Yang Baiyu Guo Hui Li Qiushi Dai Yali Liang Jun Ma Bo Wang Haiming Sun Qiunan Liu Jing Wang Congcong Du Liqiang Zhang Yongfu Tang Jianyu Huang | 2023 | Journal of Energy Chemistry2023,,7: | 0 |
| 12 | Hydrothermal sedimentation and superlarge ore deposit显示文摘HYDROTHERMAL fluids, circulated under earth surface, yielded infilling, replacement and thermal dynamic process when ascended near basin basement and resulted in sedimentation when vented into basin, anddeposited pure massive sulfide, chert, feldspar, barite, carbonate and tourmaline rocks with specialstructures, such as massive, laminated, banded, brecciated, stockwork, veinlet and vein which weredistributed in a zonation in space. Sometimes the hydrothermal sediments are mainly composed of microbios. The various types of hydrothermal sedimentary deposits are developed very well in several stages ofgeological history in China. This note will mainly discuss the hydrothermal sedimentary mineralization andthe formation of superlarge ore deposits in four metallogenic belts in China: Devonian belt in QinlingMountains; Sinian belt in South China; Middle Proterozoic belt in Inner Mongolia; Permian belt in SouthChina. 1 Devonian metallogenic belt in Qinling | CHEN Xianpei~1, CHEN Doufu~1, GAO Jiyuan~1, PAN Jingming~1, CHEN Guangqian~1, QI Shijing~2 and LI Ying~2 1. Guangzhou Institute of Geochemistry, Chinese Academy of Scienees, Guangzhou 510640, China 2. Department of Geology, Xi’an Institute of Geology, Xi’an 710054, China | 1999 | Chinese Science Bulletin1999,44,S2: | 0 |
| 13 | Mineralization of sediment-hosted ore deposits in reef-chert suite in China显示文摘THE reef-chert suite, named by Chen, mainly consists of four types of rocks, with reef carbonate in thelower part, fine detrital rocks in the upper part, chert beds with ore bodies in the intermediate, and synchronous volcanic rocks either in this sequence or in the same sequence in the neighboring district. It isformed as a fixed and ordered suite in space and time, and is the comprehensive product of normal sedimentary process, biological process in extensional basin, hydrothermal sedimentary process near basinbase and magmatic process in the deep of lithosphere in the special geological setting. Many of thesediment-hosted ore deposits usually occur in such a suite in China, such as Dajiangping pyrite deposit,Shuikoushan lead-zinc ore deposit, Changkeng gold-silver deposit, Dachang cassiterite-lead-zinc ore deposit, Xikuangshan stibium ore deposit, Changba-Lijiangou lead-zinc ore deposit, Baiyunebo | CHEN Duofu, CHEN Xiangpei, GAO Jiyuan, PAN Jingming and CHEN Guangqian Guangzbou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China | 1999 | Chinese Science Bulletin1999,44,S2: | 0 |
| 14 | Research progress on chemical constituents in Sigesbeckiae Herba and their pharmacological activities显示文摘Sigesbeckiae Herba,a dry whole plant of Sigesbeckia glabrescens Makino,Sigesbeckia pubescens Makino and Sigesbeckia orientalis L.,is a traditional Chinese medicine used to dispel dampness,dredge meridians and collaterals,clear heat and detoxicate.Its chemical components are complex and abundant,including mainly diterpenoids,sesquiterpenoids and flavonoids.Among them,diterpenoids are the main active components.Modern pharmacological studies have found that the compounds isolated from Sigesbeckiae Herba have anti-inflammatory,anti-tumor,antithrombus and other pharmacological activities.This review systematically summarized the chemical components identified from Sigesbeckiae Herba and their pharmacological activities by searching Chinese and English databases,in order to provide references for the further development of Sigesbeckiae Herba and the improvement of its quality standards. | Meiya Lian Xiaoxu Gao Jingming Jia Anhua Wang | 2021 | Asian Journal of Traditional Medicines2021,16,3: | 0 |
| 15 | Content determination of saponins and HS-GC/MS analysis of volatile components in Chinese Shizhu Panax of different growth years显示文摘HPLC and headspace-gas chromatography-mass spectrometry(HS-GC-MS)were used to investigate the content of saponins and volatile components in Chinese Shizhu Panax of different growth years.82 components were isolated from Chinese Shizhu Panax,69 components of them were successfully identified.They mainly contained monoterpenes,alkanes and sesquiterpenoids,of which sesquiterpenoids were the main components.The results indicated that the content of saponins in Chinese Shizhu Panax of different growth years was dissimilar and diverse.The content of total saponins can be enriched when properly prolonging the growth years of Chinese Shizhu Panax.However,the content of ginsenosides can reach the level in the fifth year according to Chinese Pharmacopoeia.The volatile components in Chinese Shizhu Panax of different growth years also differ in content,type and proportion of compounds to a certain degree. | Jiangchun Wei Yuning Gao Ting Yan Gaosheng Hu Anhua Wang Yurong Song Qingquan Wang Jingming Jia | 2020 | Asian Journal of Traditional Medicines2020,15,3: | 0 |
| 16 | Research progress on chemical constituents in Sophora alopecuroides L.and their pharmacological activities显示文摘Sophora alopecuroides L.,a perennial plant belonging to Leguminosae family,is used as medicinal materials to treat a variety of skin diseases.Its chemical components are complex and diverse,mainly including alkaloids and flavonoids.Modern pharmacological studies have found that the isolated compounds from S.alopecuroides have a variety of pharmacological activities.In particular,alkaloids represented by matrine,aloperine and oxymatrine have significant anti-inflammatory,anti-viral,anti-tumor,anti-bacterial and immunomodulatory activities.This paper summarized the chemical constituents and pharmacological activities of S.alopecuroides,aiming to provide the basis for further research. | Bohan Yang Jing Wang Xiaoxu Gao Jingming Jia Anhua Wang | 2021 | Asian Journal of Traditional Medicines2021,16,5: | 0 |