|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Advanced prediction of tunnel boring machine performance based on big data显示文摘Predicting the performance of a tunneling boring machine is vitally important to avoid any possible accidents during tunneling boring.The prediction is not straightforward due to the uncertain geological conditions and the complex rock-machine interactions.Based on the big data obtained from the 72.1 km long tunnel in the Yin-Song Diversion Project in China,this study developed a machine learning model to predict the TBM performance in a real-time manner.The total thrust and the cutterhead torque during a stable period in a boring cycle was predicted in advance by using the machine-returned parameters in the rising period.A long short-term memory model was developed and its accuracy was evaluated.The results show that the variation in the total thrust and cutterhead torque with various geological conditions can be well reflected by the proposed model.This real-time predication shows superior performance than the classical theoretical model in which only a single value can be obtained based on the single measurement of the rock properties.To improve the accuracy of the model a filtering process was proposed.Results indicate that filtering the unnecessary parameters can enhance both the accuracy and the computational efficiency.Finally,the data deficiency was discussed by assuming a parameter was missing.It is found that the missing of a key parameter can significantly reduce the accuracy of the model,while the supplement of a parameter that highly-correlated with the missing one can improve the prediction. | Jinhui Li Pengxi Li Dong Guo Xu Li Zuyu Chen | 2021 | Geoscience Frontiers2021，12，1： | 17 |
| 2 | Early-Mid Ordovician brachiopod diversification in South China显示文摘Affected by paleogeographic position, paleoclimatic condition and depositional environments, the increase of the Early-Mid Ordovician brachiopod diversity of South China commenced at the beginning of the Ordovician (early Tremadoc), accelerated from the Tetra- graptus approximatus Biozone (base of Arenig), and reached its first acme in the Didymograptus eobifidus Biozone (mid early Arenig) when the number of brachiopod genera was over 7 times as great as that at the start of the Ordovician. This was the first radiation in the history of brachiopod macroevolution in South China, which occurred nearly 5 graptolitic biozones earlier than the global trend of the great Ordovician biodiversification (in the lower part of the Undulograptus austrodentatus Biozone). It is also characterized by (1) the origination or first occurrences of some major groups, such as the punctate dalmanelloids and the pseudopunctate stro- phomenoids including Plectambonitoidea (cardinal process simple or absent) and Stro- phomenoidea (cardinal process bilobed) in South China; (2) niche expansion, particularly in the first occupation of deeper water benthic regimes by the Euorthisina-Nocturnellia Association developed at Houping, Chengkou, northern Chongqing; and (3) the differentiation of brachiopod faunas under different environmental conditions. The gradual and increasing separation from Gondwana may have been one of the factors responsible for the radiation in South China. | ZHAN Renbin, RONG Jiayu, CHENG Jinhui & CHEN Pengfei Nanjing Institute of Geology and Palaeontology, Chinese Academy of Sciences State Key Laboratory of Palaeobiology and Stratigraphy, Nanjing 210008, China | 2005 | Science China Earth Sciences2005，48，5： | 14 |
| 3 | Biological characteristics of an improved triploid crucian carp显示文摘An improved triploid crucian carp(ITCC) was produced by crossing improved tetraploids(G1×AT,) with improved red crucian carp(IRCC,),which were obtained by distant crossing and gynogenesis.The biological characteristics of ITCC,including the number and karyotype of chromosomes,gonadad and pituitary structures,phenotype,and growth rate are reported.ITCC possessed 150 chromosomes with the karyotype 33m+51sm+33st+33t.In the breeding season,both ovary-like and testis-like gonads of ITCC were unable to produce normal mature gametes.The ultrastructure of the pituitary of ITCC showed that most of the endocrine granules in gonadotrophic hormone(GTH) cells had not been released,providing endocrinological evidence for the sterility of ITCC.Compared with triploid crucian carp(TCC) produced by mating Japanese crucian carp with allotetraploid hybrids,ITCC not only retained the excellent traits of fast growth rate and sterility,but also acquired improved morphological characteristics,including higher body,shorter tail and smaller head. | CHEN Song,WANG Jing,LIU ShaoJun,QIN QinBo,XIAO Jun,DUAN Wei,LUO KaiKun,LIU JinHui & LIU Yun Key Laboratory of Protein Chemistry and Developmental Biology of State Education Ministry of China,College of Life Sciences,Hunan Normal University,Changsha 410081,China | 2009 | Science China(Life Sciences)2009，52，8： | 14 |
| 4 | Comparative biomechanical study of reversed less invasive stabilization system and proximal femoral nail antirotation for unstable intertrochanteric fractures显示文摘 | Chen Ying Liu Shouyao Lin Peng Wang Yunting Wang Jinhui Tao Jianfeng Cai Rongrong | 2014 | Chinese Medical Journal2014，，23： | 13 |
| 5 | Esophageal cancer:Epidemiology,risk factors and screening显示文摘More than 600,000 people are diagnosed with esophageal cancer(EC)every year globally,and the five-year survival rate of EC is less than 20%.Two common histological subtypes of EC,esophageal squamous cell carcinoma(ESCC)and esophageal adenocarcinoma(EAC),have great geographical variations in incidence rates.About half of the world’s EC was diagnosed in China and a majority of which belong to ESCC.Globally,the overall incidence rate of EC is decreasing.In some high-risk Asian regions,such as China,the incidence rate of ESCC has generally declined,potentially due to economic growth and improvement of diet habits.In some European high-income countries and the United States,the decline is mainly attributed to the decrease in smoking and drinking.The risk factors of EC are not well understood,and the importance of environmental and genetic factors in the pathogenesis is also unclear.The incidence and mortality of advanced EC can be reduced through early diagnosis and screening.White light endoscopy is still the gold standard in the current screening technology.This article reviews the epidemiology,risk factors,and screening strategies of EC in recent years to help researchers determine the most effective management strategies to reduce the risk of EC. | Jiang Li Jianguo Xu Yadi Zheng Ya Gao Siyi He He Li Kaiyong Zou Ni Li Jinhui Tian Wanqing Chen Jie He | 2021 | Chinese Journal of Cancer Research2021，33，5： | 12 |
| 6 | Stem Cell Regulation by Arabidopsis WOX Genes显示文摘功能的多样化跟随的基因扩大是在进化的主要力量。这的一个典型例子在 WUSCHEL 相关的 HOMEOBOX (WOX ) 基因家庭被看见,依照 Arabidopsis 干细胞管理者 WUSCHEL 命名。这里,我们在 WOX 基因家庭分析功能的分叉。除了形成层干细胞管理者 WOX4, WUS clade 的成员能在射击和花的干细胞维护代替 WUS 功能到不同的度。WUS 的干细胞功能要求正规 WUS 盒子,为和 TPL/TPR 合作抑压者的相互作用必要,而压抑的耳朵领域是非必需的,酸的领域仅仅似乎为女富饶被要求。与 WUS clade 相对照,古老的 WOX13 和 WOX9 clades 的成员不能支持干细胞维护。尽管 homeodomains 在 WUS 和 WOX9 clade 成员之间是可互换的,和正规 WUS 盒子的 WUS 兼容的 homeodomain 不为干细胞维护是足够的。我们的结果建议在射击和 Arabidopsis 的花的分裂组织的那个 WOX 函数被限制为现代 WUS clade,建议干细胞控制是一个导出的函数。除了 homeodomain 和 WUS 盒子的然而未被发现的功能的领域为这功能是必要的。 | Alicja Dolzblasz Judith Nardmann Elena Clerici Barry Causier Eric van der Graaff Jinhui Chen Brendan Davies Wolfgang Werr Thomas Laux | 2016 | Molecular Plant2016，9，7： | 11 |
| 7 | Formation and biological characterization of three new types of improved crucian carp显示文摘The improved tetraploids (G1×AT) were obtained by distant crossing and gynogenesis and the high-body individuals accounted for 2% among G1×AT. After mating with each other, the high-body in- dividuals produced three kinds of bisexual fertile diploid fishes: high-body red crucian carp, high-body fork-like-tails goldfish and gray common carp. The high-body red crucian carp mating with each other formed three types of improved crucian carp (ICC) including improved red crucian carp (IRCC), im- proved color crucian carp (ICCC) and improved gray crucian carp (IGCC). The phenotypes, chromo- some numbers, gonadal structure and fertility of the three kinds of ICC and their offspring were observed. All the three kinds of ICC possessed some improved phenotypes such as higher body, smaller head and shorter tail. The ratios of the body height to body length of IRCC, ICCC and IGCC were 0.54, 0.51 and 0.54, respectively. All of them were obviously higher than that of red crucian carp 0.41 (P<0.01). Three kinds of ICC had the same chromosome number as red crucian carp with 100 chromosomes. All the ICC possessed normal gonads producing mature eggs or sperm, which was important for the production of an improved diploid population. Compared with red crucian carp, all the ICC had stronger fertility such as higher gametes production, higher fertilization rate and higher hatchery rate. Three types of improved diploid fish population were generated from the three kinds of ICC by self-crossing, respectively. The ICC can serve as ornamental fish and edible fish. They are also ideal parents to produce triploids by mating with tetraploids. The new ICC plays an important role in biological evolution and fish genetic breeding. | WANG Jing, QIN QinBo, CHEN Song, LIU ShaoJun, DUAN Wei, LIU JinHui, ZHANG Chun, LUO KaiKun, XIAO Jun & LIU Yun Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education of China, College of Life Sciences, Hunan Normal University, Changsha 410081, China | 2008 | Science China(Life Sciences)2008，51，6： | 8 |
| 8 | Transcriptome analysis and metabolic profiling reveal the key role of carotenoids in the petal coloration of Liriodendron tulipifera显示文摘Liriodendron tulipifera,also known as tuliptree,is a popular ornamental horticultural plant with extraordinary tulipshaped flowers characterized by an orange band near their base.The mechanisms underlying petal band-specific pigmentation during L.tulipifera flower development are unclear.Here,we combined nontargeted and targeted metabolomics and transcriptomics to identify a pathway cascade leading to carotenoid biosynthesis that is specifically activated in the petal band.The comparative analysis of carotenoid metabolites between L.tulipifera and Liriodendron hybrids indicates thatγ-carotene,a rare carotene in plants,is the most likely orange pigment responsible for the coloration of the petal band.Phenotypic and transcriptomic analyses of developing petals reveal that the band area is first predefined by the loss of green color.Later,the band is maintained by locally activating and repressing carotenoid and chlorophyll biosynthesis genes,respectively.Two rate-limiting genes of carotene biosynthesis,carotenoid isomerase(CRTISO)and epsilon lycopene cyclase(ε-LCY),encode the core enzymes responsible for petal band-specific orange pigmentation in L.tulipifera.In particular,a putative additionalε-LCY copy specific to L.tulipifera may contribute to the distinct petal coloration pattern,compared with L.chinense.Taken together,our work provides a first glimpse of the metabolome and transcriptome dynamics in tuliptree flower coloration and provides a valuable resource for flower breeding or metabolic engineering as well as for understanding flower evolution in an early woody angiosperm. | Zhaodong Hao Siqin Liu Lingfeng Hu Jisen Shi Jinhui Chen | 2020 | Horticulture Research2020，7，1： | 7 |
| 9 | Synthesis and electrochemical performances of LiCoO_2 recycled from the incisors bound of Li-ion batteries显示文摘A new LiCoO2 recovery technology for Li-ion batteries was studied in this paper. LiCoO2 was peeled from the Al foil with dimethyl acetamide (DMAC), and then polyvinylidene fluoride (PVDF) and carbon powders in the active material were eliminated by high temperature calcining. Subsequently, Li2CO3, LiOH·H2O and LiAc·2H2O were added into the recycled powders to adjust the Li/Co molar ratio to 1.00. The new LiCoO2 was obtained by calcining the mixture at 850°C for 12 h in air. The structure and morphology of the recycled powders and resulting samples were studied by XRD and SEM techniques, respectively. The layered structure of LiCoO2 synthesized by adding Li2CO3 is the best, and it is found to have the best characteristics as a cathode material in terms of charge-discharge capacity and cycling performance. The first discharge capacity is 160 mAh·g-1 between 3.0-4.3 V. The discharge capacity after cycling for 50 times is still 145.2 mAh·g-1. | LI Jinhui ZHONG Shengwen XIONG Daoling CHEN Hao | 2009 | Rare Metals2009，28，4： | 6 |
| 10 | Low-complexity optimal spatial channel pairing for AF-based multi-pair two-way relay networks显示文摘This paper considers a multi-pair two-way relay system with multi-antenna users and proposes a low-complexity optimal spatial channel pairing(SCP) strategy at the relay station(RS) for such a system. The proposed SCP scheme, following the BD-like beamformer at RS, pairs the uplink spatial subchannels of each user pair with the corresponding downlink spatial subchannels by maximizing sum-rate(Max-SR). Furthermore, a new mathematical inequality(arrangement inequalities of a product) is developed and applied to obtain sufficient and necessary conditions for achieving Max-SR-SCP. This also yields a simple low-complexity implementation of the proposed SCP in contrast to the NP-hard complexity of the original Max-SR-SCP problem. Simulation results illustrate that the proposed Max-SR-SCP achieves substantial sum-rate gains over other pairing schemes. | SHU Feng CHEN Yu YOU XiaoHu LU JinHui | 2014 | Science China(Information Sciences)2014，57，10： | 6 |
| 11 | Multidisciplinary design optimization of adaptive wing leading edge显示文摘Adaptive wing can significantly enhance aircraft aerodynamic performance, which refers to aerodynamic and structural opti-mization designs. This paper introduces a two-step approach to solve the interrelated problems of the adaptive leading edge. In the first step, the procedure of airfoil optimization is carried out with an initial configuration of NACA 0006. On the basis of the combination of design of experiment (DOE), response surface method (RSM) and genetic algorithm (GA), an adaptive air-foil can be obtained whose lift-to-drag ratio is larger than the baseline airfoil's at the given angle of attack and subsonic speed.The next step is to design a compliant structure to achieve the target airfoil shape, which is the optimization result of the previous step. In order to minimize the deviation of the deformed shape from the target shape, the load path representation topology method is presented. This method is developed by way of GA, with size and shape optimization incorporated in it simul-taneously. Finally, a comparison study with the Solid Isotropic Material with Penalization (SIMP) method in Altair OptiStruct is conducted, and the results demonstrate the validity and effectiveness of the proposed approach. | SUN RuJie CHEN GuoPing ZHOU Chen ZHOU LanWei JIANG JinHui | 2013 | Science China(Technological Sciences)2013，56，7： | 5 |
| 12 | The art of two-dimensional soft nanomaterials显示文摘The discovery of graphene has triggered the explosive development of two-dimensional(2D) nanomaterials, including both inorganic and organic species. Benefiting from the simple elemental composition, inorganic 2D nanomaterials were the center research in the past decade, which has long shadowed the research of 2D organic(or soft) nanomaterials. Although many kinds of2D soft nanomaterials have been successfully prepared, a unified definition for them is still impossible due to the complicate and quite different chemical structures between each other and even relying on totally different techniques to distinguish them. Since our first review on 2D soft nanomaterials in 2015, this field has moved forward with big success. In this review, we will focus on the development of 2D soft nanomaterials after 2015. In order to deliver better overview of this field, new and comprehensive classification is used in this review: 2D aromatic molecules, graphene and graphene nanoribbons, graphyne and graphdiyne,BxCyNznanosheets, 2D polymers, 2D supramolecules, crystalline 2D assemblies, 2D covalent organic frameworks, 2D metalorganic frameworks, sandwich-like 2D porous polymers, 2D polymer nanosheets, etc. The focus of this review lies on synthetic strategies and the challenges of characterization, definition and fundamental understanding. | Caini Zheng Jinhui Zhu Chongqing Yang Chenbao Lu Zhenying Chen Xiaodong Zhuang | 2019 | Science China Chemistry2019，62，9： | 5 |
| 13 | Overview and outlook on railway track stiffness measurement显示文摘Stiffness is one of the basic performance parameters for railway track. The efficient and accurate stiffness measurement has been considered as the foundation for further development of railway engineering, and therefore has great theoretical and practical significance.Based on a summary of the connotation and measurement of track stiffness, the state of the art of measurement methods for track stiffness was analyzed systematically.The standstill measurement of track stiffness can be performed with the traditional jack-loading method, impact hammer method, FWD(falling weight deflectometer)method, and track loading vehicle method. Although these methods can be adopted in stiffness measurement for a section of railway track, they are not desirable owning to small range and low efficiency. In the recent 20 years,researchers have proposed many methods like unbalancedloading laser displacement method, deflection basin deformation rate method, and eccentricity excitation method to continuously measure track stiffness; however,these methods have drawbacks like poor accuracy, low speed, and insufficient data analysis. In this work, the merits and demerits of these methods were summarized,and optimization suggestions were presented. Based on the wave transmission mechanism and principle of vibration energy harvesting, an overall conception on continuous measurement of stiffness and long-term stiffness monitoring for special sections was proposed. | Ping Wang Li Wang Rong Chen Jinhui Xu Jinmang Xu Mingyuan Gao | 2016 | Journal of Modern Transportation2016，24，2： | 5 |
| 14 | Unexpected catalytic activity of rhodium nanodendrites with nanosheet subunits for methanol electrooxidation in an alkaline medium显示文摘Rh 的 Nanocrystals,高贵金属催化剂家庭的一个重要成员,在异构的催化反应有宽应用。控制这些高贵金属 nanocrystals 的形态学为改进他们的催化活动和耐久性成为了有效策略。在这个工作,有很薄的三角形的分支的明确的 Rh nanodendrites 用一个灵巧的 diethylene 乙二醇减小方法作为子单元被综合,作为一个复杂形成的代理人和表面活化剂由 polyethyleneimine 帮助了。第一次,有明确的形态学的 Rh nanocrystals 上的甲醇氧化反应(粗腐殖质) 在碱的媒介用各种各样的电气化学的技术被调查。出人意料地,同样准备的 Rh nanodendrites 与 ultrathin nanosheet 子单元,在碱的媒介在 MOR 期间展出优异 electrocatalytic 活动和耐久性,与特定的形态学显示那 Rh nanocrystals 可以是在在碱的媒介的 MOR 的磅 electrocatalysts 的高度有希望的选择。 | Yongqiang Kang Fumin Li Shuni Li Pujun Jin Jinhui Zeng Jiaxing Jiang Yu Chen | 2016 | Nano Research2016，9，12： | 5 |
| 15 | Principles and Characteristics of Polymerization-Induced Self-Assembly with Various Polymerization Techniques显示文摘A chemical reaction that drives a physical polymer selfassembly process,namely,polymerization-induced self-assembly(PISA),combines block copolymer synthesis and nanoparticle formation efficiently at high polymer concentrations.Various nanoparticlemorphologies such as spheres,worms,and vesicles can be prepared readily in polar and nonpolarmedia.PISA has been well developed in combination with reversible addition-fragmentation chain transfer(RAFT)polymerization.Notably,developments with other polymerization methods are also achieved.In this report,first,we discuss the general principles of RAFT-PISA and the nanoparticles generated from this method.Specifically,new insights into polymer nucleation and subsequent morphological evolution are highlighted.Subsequently,PISA formulations that use other polymerization methods[atom transfer radical polymerization(ATRP),nitroxide-mediated polymerization(NMP),ring-opening metathesis polymerization(ROMP),and ring-opening polymerization(ROP)of N-carboxyanhydrides(NCAs)]are summarized in detail.Finally,more exotic PISA formulations are emphasized:these are based on organotelluriummediated living radical polymerization(TERP),living anionic polymerization(LAP),addition-fragmentation chain transfer(AFCT)polymerization,reversible complexation-mediated polymerization(RCMP),and cobalt-mediated radical polymerization(CMRP),or utilize a comonomer that undergoes radical ringopening polymerization(rROP).This reviewis concluded with a perspective on the status and potential of PISA. | Erik Jan Cornel Jinhui Jiang Shuai Chen Jianzhong Du | 2021 | CCS Chemistry2021，3，4： | 4 |
| 16 | Goldfish vsx1 inhibits chordamesoderm gene ntl expression at the dorsal midline显示文摘vsx1(visual system homeobox-1),a homeobox gene originally identified from an adult goldfish retinal cDNA library,has been shown to regulate retina progenitor proliferation,differentiation and functional maintenance of bipolar cells in vertebrates.However,in all the examined vertebrate species,vsx1 transcripts can be also detected at the early developmental stage,suggesting that it may play an important role in regulating early embryogenesis as well.Here,we investigated the function of vsx1 in early embryogenesis of goldfish(Carassius auratus) with both overexpression and gene knockdown approaches.It was found that vsx1 overexpression specifically blocked dorsal midline structure for-mation and vsx1 knockdown led to disorganized dorsal midline structure.Whole-mount in situ hy-bridization revealed that the midline expression of ntl,a key regulatory gene for chordamesoderm,was repressed by vsx1 overexpression but enhanced in the vsx1 knockdown.Furthermore,VSX1 protein could bind ntl promoter directly and was sufficient to inhibit ntl promoter-driven reporter gene green fluorescence protein transcription.Together,these results suggested that vsx1 may act to repress ec-topic expression of ntl in neural progenitor cells to ensure neural tube development in a spatially coordinated pattern during early embryogenesis. | LIU ZhengHua CHEN JinHui MA ShanShan TONG Ying LUO Chen | 2009 | Chinese Science Bulletin2009，54，8： | 4 |
| 17 | The role of γ-aminobutyric acid in aluminum stress tolerance in a woody plant, Liriodendron chinense×tulipifera显示文摘The aluminum(Al)cation Al^(3+)in acidic soil shows severe rhizotoxicity that inhibits plant growth and development.Most woody plants adapted to acidic soils have evolved specific strategies against Al^(3+)toxicity,but the underlying mechanism remains elusive.The four-carbon amino acid gamma-aminobutyric acid(GABA)has been well studied in mammals as an inhibitory neurotransmitter;GABA also controls many physiological responses during environmental or biotic stress.The woody plant hybrid Liriodendron(L.chinense×tulipifera)is widely cultivated in China as a horticultural tree and provides high-quality timber;studying its adaptation to high Al stress is important for harnessing its ecological and economic potential.Here,we performed quantitative iTRAQ(isobaric tags for relative and absolute quantification)to study how protein expression is altered in hybrid Liriodendron leaves subjected to Al stress.Hybrid Liriodendron shows differential accumulation of several proteins related to cell wall biosynthesis,sugar and proline metabolism,antioxidant activity,cell autophagy,protein ubiquitination degradation,and anion transport in response to Al damage.We observed that Al stress upregulated glutamate decarboxylase(GAD)and its activity,leading to increased GABA biosynthesis.Additional GABA synergistically increased Al-induced antioxidant enzyme activity to efficiently scavenge ROS,enhanced proline biosynthesis,and upregulated the expression of MATE1/2,which subsequently promoted the efflux of citrate for chelation of Al^(3+).We also showed similar effects of GABA on enhanced Al^(3+)tolerance in Arabidopsis.Thus,our findings suggest a function of GABA signaling in enhancing hybrid Liriodendron tolerance to Al stress through promoting organic acid transport and sustaining the cellular redox and osmotic balance. | Pengkai Wang Yini Dong Liming Zhu Zhaodong Hao LingFeng Hu Xiangyang Hu Guibin Wang Tielong Cheng Jisen Shi Jinhui Chen | 2021 | Horticulture Research2021，8，1： | 3 |
| 18 | Degradation of furan tebufenozide in laboratory and field trials显示文摘Furan tebufenozide is a newly developed insect growth regulator and has been applied as a pesticide in agriculture in China.Its degradation under both laboratory and field conditions was investigated,and the degradation kinetics was fitted by simple first order kinetics (SFO) model and first order double exponential (FOD) model.Laboratory studies were conducted with or without light in five simulated media (sterilized deionized water,river water,soil solution,sterilized soil and natural soil).No dissipations of furan tebufenozide were observed in sterilized aqueous and soil media under light prevented conditions,whereas degradation occurred under all the other conditions in the laboratory.Derived from SFO and FOD models,DT50 in the dark and light laboratory conditions was in the range of 39.7-82.5 and 1.1-8.0 days,respectively.These results indicated that microbes and light were the main factors for the degradation of the pesticide in the laboratory.During field trials,derived from the SFO model,DT50 and DT90 were 30.3 and 100.5 days,while derived from the FOD model,DT50 and DT90 were 28.9 and 274.9 days,respectively.Compared with laboratory experiments,field trials were influenced by multiple factors.Therefore,the SFO model could not fit experimental data as well as the FOD model did in field trials. | GUO Cong,LI DaHui,CHEN JinHui,GUO BaoYuan,WANG HuiLi & LI JianZhong Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences,Beijing 100085,China | 2010 | Science China Chemistry2010，53，8： | 3 |
| 19 | The EffectofLocally Im planted Com plexes of Adriam ycin-Hydroxyapatite Com plexes on Tum or —— Study of A NewAlternative Treatm entfor Hepatic Cancer显示文摘A new targeting anticancer system was prepared by using hydroxyapatite particles (2 mm in diameter) as carrier material and adriamycin as anticancer agent. The adsorption and release properties of the complexes were assayed by fluorometry in vivo and in vitro and the curative effect on W 256 sarcoma of rat was observed. The results showed that one particle of hydroxyapatite could adsorb approximately 0.08 mg adriamycin and they can maintain a steady and slow release of adriamycin from hydroxyapatite for one month. When hydroxyapatite adriamycin complexes were implanted into the liver of rat, liver adriamycin concentration at the implanted region was obviously higher than that achieved by injection of adriamycin solution. The locally implanted complexes obviously inhibited the growth of subcutaneous implanted tumor of rat, and increased the survival rate of rat with implanted liver tumor. | XIA Qinghua ) 1, NIE Haiyang 2, CHEN Daoda, CHEN Jianying, TIAN Yuan, ZHANG Jinhui 1 Department of General Surgery, Xiehe Hospital, Tongji Medical University, Wuhan 430022 2 Department of Orthopedics, Puqi Peoples Hospital, Puqi 437300 | 1999 | Journal of Huazhong University of Science and Technology(Medical Sciences)1999，19，3： | 3 |
| 20 | Genome-wide identification and cold stress-induced expression analysis of the CBF gene family in Liriodendron chinense显示文摘Cold-resistance pathways that operate in model plants such as Arabidopsis thaliana and Oryza sativa have been studied extensively.It has been found that CBF genes play an important role in plant cold resistance.Liriodendron chinense,a tree known for its graceful tree shape and widely spread in south China,has weak cold tolerance.However,little is known about its response to cold.To further study the function of L.chinense CBF gene family,we started by characterizing all members of this gene family in the L.chinense genome and their expression profiling.Phylogenetic analysis found that 14 CBF genes in L.chinense are more closely related to their homologues in woody plants and A.thaliana than those in O.sativa.Cis-acting elements and GO analysis showed that some LcCBF genes participated in the biological process of cold stress response.The transcriptomic and RT-qPCR data showed that most of LcCBF genes displayed an initially increasing and subsequently decreasing trend during cold stress course and the expression profile of each member was different.Some LcCBF genes exhibited a different abundance in callus,root,stem and leaf tissues.The structure and expression characteristics of LcCBF genes imply that they may have similar and different functions in response to cold stress conditions.The identification and analysis of LcCBF gene family have laid the foundation for future studies into L.chinense cold stress mechanisms and for the cultivation of cold-resistance cultivars. | Yuanlin Guan Siqin Liu Weihuang Wu Kaiyue Hong Rongxue Li Liming Zhu Yang Liu Ye Lu Jinhui Chen Liming Yang Jisen Shi | 2021 | Journal of Forestry Research2021，32，6： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员