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| 1 | Water quality monitoring in a slightly-polluted inland water body through remote sensing-Case study of the Guanting Reservoir in Beijing,China显示文摘This study focused on the water quality of the Guanting Reservoir,a possible auxiliary drinking water source for Beijing.Through a remote sensing(RS)approach and using Landsat 5 Thematic Mapper(TM)data,water quality retrieval models were established and analyzed for eight common water quality variables,including algae content,turbidity,and concentrations of chemical oxygen demand,total nitrogen,ammonia nitrogen,nitrate nitrogen,total phosphorus,and dissolved phosphorus.The results show that there exists a statistically significant correlation between each water quality variable and remote sensing data in a slightly-polluted inland water body with fairly weak spectral radiation.With an appropriate method of sampling pixel digital numbers and multiple regression algorithms,retrieval of the algae content,turbidity,and nitrate nitrogen concentration was achieved within 10% mean relative error,concentrations of total nitrogen and dissolved phosphorus within 20%,and concentrations of ammonia nitrogen and total phosphorus within 30%.On the other hand,no effective retrieval method for chemical oxygen demand was found.These accuracies were acceptable for the practical application of routine monitoring and early warning on water quality safety with the support of precise traditional monitoring.The results show that performing the most traditional routine monitoring of water quality by RS in relatively clean inland water bodies is possible and effective. | Weiqi HE Shan CHEN Xuehua LIU Jining CHEN | 2008 | Frontiers of Environmental Science & Engineering2008，2，2： | 10 |
| 2 | Clinical relationship between MDR1 gene and gallbladder cancer显示文摘BACKGROUND: The most common mechanisms of mul- tidrug resistance (MDR) in cancer cells is the expression of an energy-dependent exfflux pump. P-glycoprotein (P-gp) encoded by MDR1 gene and multidrug associated protein (MRP) are well known proteins associated with MDR. In human cancers, the MDR1 gene expression is common in patients with intrinsic and acquired MDR. It is a major therapeutic problem in cancer chemotherapy. Previously we found that the MDR of HCC is related to MRP gene ex- pression and initiates the intrinsic MDR. The aim of this study is to study the expression of MDR1 gene encoding P-gp and MDR1 mRNA in primary gallbladder carcinoma, and analyze its clinical significance. METHODS: Immunohistochemistry (IHC) S-P method and in situ polymerase chain reaction (ISPCR) were used to detect the expression of P-gp and MDR1 mRNA in 53 cases of untreated primary gallbladder carcinoma and 12 ca- ses of cholecystitis (archival paraffin-embedded tissues). RESULTS: The positive expression rates of P-gp and MDR1 mRNA in the 53 cases and 12 cases were 60.38%, 71.69% and 25.00%, 33.33%, respectively. There was a significant difference between the two groups (P<0.05). The positive expression rate of P-gp and MDRlmRNA were 69.44%, 83.33% and 41.18%, 47.06% respectively in tissues in stage of Nevin against Nevin , (P<0.05). In well, moderately differentiated gallbladder carcinoma tissues, their expressions were 79.49%, 69.23% against 50.00%, 35.71% in low, undifferentiated tissues (P<0.05). CONCLUSIONS: MDR to gallbladder carcinoma is closely related to the intrinsic MDR and it provides an important evidence to reverse the MDR by detection of the MDR1gene. Meanwhile, MDR1 gene expression in gallbladder carcinoma is correlated with some biological characteris- tics , takes part in the carcinogenesis of gallbladder tissues, and acts as a valuable biomarker of prognosis. | Bai-Lin Wang, Hai-Ying Zhai, Bing-Yi Chen, Shu-Ping Zhai, Hai-Yan Yang, Xiao-Ping Chen, Wen-Tao Zhao and Lei Meng Guangzhou, China Third Department of Surgery, First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, China Depart- ment of Surgery, First People’s Hospital, Jining 272100, China Department of Surgery, General Hospital of PLA, Beijing 100853, China and Hepatic Surgery Center, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，2： | 9 |
| 3 | Molecular diversity of arbuscular mycorrhizal fungi at a large-scale antimony mining area in southern China显示文摘Arbuscular mycorrhizal fungi(AMF) have great potential for assisting heavy metal hyperaccumulators in the remediation of contaminated soils. However, little information is available about the community composition of AMF under natural conditions in soils contaminated by antimony(Sb). The objective of this study was to investigate the characteristics of AMF molecular diversity, and to explore the effects of Sb content and soil properties on the AMF community structure in an Sb mining area. Four Sb mine spoils and one adjacent reference area were selected from around the Xikuangshan mine in southern China. The association of AMF molecular diversity and community composition with the rhizosphere soils of the dominant plant species was studied by Polymerase Chain Reaction-Denaturing Gradient Gel Electrophoresis(PCR-DGGE). Results from all five studied sites showed that the diversity of AMF decreased with increasing Sb concentration. Principal component analysis(PCA) indicated that the AMF community structure was markedly different among these groups. Further redundancy analysis(RDA) showed that Sb contamination was the dominating factor influencing the AMF community structure in the Sb mine area. However, the multivariate analysis showed that, apart from the soil Sb content, extractable nitrogen content and organic matter content also attributed to AMF sequence distribution type. Some AMF sequences were only found in the highly contaminated area and these might be ideal candidates for improving phytoremediation efficiency in Sb mining regions. Gene sequencing analysis revealed that most species were affiliated with Glomus, suggesting that Glomus was the dominant AMF genus in the studied Sb mining area. | Yuan Wei Zhipeng Chen Fengchang Wu Hong Hou Jining Li Yuxian Shangguan Juan Zhang Fasheng Li Qingru Zeng | 2015 | Journal of Environmental Sciences2015，27，3： | 6 |
| 4 | Sustainability of urban drainage management: a perspective on infrastructure resilience and thresholds显示文摘 | Xiong NING Yi LIU Jining CHEN Xin DONG Wangfeng LI Bin LIANG | 2013 | Frontiers of Environmental Science & Engineering2013，7，5： | 4 |
| 5 | Substance flow analysis for an urban drainage system of a representative hypothetical city in China显示文摘这篇论文作为一个工具讨论物质流动分析(SFA ) 的使用在城市的排水系统上支持确定的研究。基于集体平衡的原则,一个静态的物质流动模型被建立在中国描述并且检验水,对一个代表性的假想城市( RH 城市)的化学的氧要求(货到付款),全部的氮( TN )和全部的磷( TP )的线路和紧张,它是用在国家水平的城市的情形的统计特征的一个设计并且可伸缩的城市。通过在 2010 的城市的排水系统的水,货到付款, TN 和 TP 的年度流动是 5510 万 m,这被估计 < 啜 class= “ a-plus-plus ” > 3 , 16037.3 t, 1649.5 t 和 209.7 t 分别地。废水处理植物(WWTP ) 的自河为污染物质排出物作为最重要的小径被识别,它作出贡献约 60% 货到付款, 65% TN 和到收到的 50% TP 流水。在废水处理过程, 100 万 m3, 7042.5 t, 584.2 t 和四的 161.4 t 期间,学习物质被播送了进污泥,同时,货到付款的 3813.0 t 和 TN 的 394.0 t 被变换成并且射出空气。与 2000 的代表性的假想城市相比,城市的人口和城市的造的区域的区域在十年期间分别地在约 90% 和 80% 膨胀了,导致进城市的排水系统的物质的输入的非常三方面的增加。由于城市的排水系统的开发,总数大量城市在类似的水平被维持。 | Hua BAI Siyu ZENG Xin DONG Jining CHEN | 2013 | Frontiers of Environmental Science & Engineering2013，7，5： | 3 |
| 6 | EXISTENCE OF MULTIPLE POSITIVE SOLUTIONS TO SINGULAR SECOND ORDER NEUMANN BOUNDARY VALUE PROBLEMS显示文摘Using the fixed point index in cones, we study the existence of one and two positive solutions to singular second order Neumann boundary value problems under some conditions, which concerns the first eigenvalue of the relevant linear problem. Our results improve and extend some known ones in the previous literature. | Xiangping Chen, Rengui Li (Dept. of Math., Jining University, Qufu 273155, Shandong) | 2010 | Annals of Differential Equations2010，26，2： | 3 |
| 7 | Mining of a streptothricin gene cluster from Streptomyces sp.TP-A0356 genome via heterologous expression显示文摘Streptothricins (STs) are used commercially to treat bacterial and fungal diseases in agriculture. Mining of the sequenced microbial genomes uncovered two cryptic ST clusters from Streptomyces sp. C and Streptomyces sp. TP-A0356. The ST cluster from S. sp. TP-A0356 was verified by successful heterologous expression in Streptomyces coelicolor M145. Two new ST analogs were produced together with streptothricin F and streptothricin D in the heterologous host. The ST cluster was further confirmed by inactivation of gene stnO, which was proposed encoding an aminomutase supplying -lysines for the poly-β-Lys chain formation. A putative biosynthetic pathway for STs is proposed based on bioinformatics analyses of the ST genes and experimental evidence. | LI JinE GUO ZhengYan HUANG Wei MENG XiangXi AI GuoMin TANG GongLi CHEN YiHua | 2013 | Science China(Life Sciences)2013，56，7： | 3 |
| 8 | Predicting future dynamics from short-term time series using an Anticipated Learning Machine显示文摘Predicting time series has significant practical applications over different disciplines.Here,we propose an Anticipated Learning Machine(ALM)to achieve precise future-state predictions based on short-term but high-dimensional data.From non-linear dynamical systems theory,we show that ALM can transform recent correlation/spatial information of high-dimensional variables into future dynamical/temporal information of any target variable,thereby overcoming the small-sample problem and achieving multistep-ahead predictions.Since the training samples generated from high-dimensional data also include information of the unknown future values of the target variable,it is called anticipated learning.Extensive experiments on real-world data demonstrate significantly superior performances of ALM over all of the existing 12 methods.In contrast to traditional statistics-based machine learning,ALM is based on non-linear dynamics,thus opening a new way for dynamics-based machine learning. | Chuan Chen Rui Li Lin Shu Zhiyu He Jining Wang Chengming Zhang Huanfei Ma Kazuyuki Aihara Luonan Chen | 2020 | National Science Review2020，7，6： | 3 |
| 9 | The multi-soliton solutions of the CH-γ equation显示文摘This paper solves the integrable CH-γequation for analytical multiple soliton solutions with the Darboux transformation method.Some properties of the soliton solutions are different from the CH equation. | CHEN ChunLi~(1+) LI YiShen~2 ZHANG JinE~3 1 Department of Mathematics,Shanghai Jiaotong University,Shanghai 200240,China 2 Department of Mathematics,University of Science and Technology of China,Hefei 230026,China 3 SB and SEF,University of Hong Kong,Pokfulam Road,Hong Kong,China | 2008 | Science China Mathematics2008，51，2： | 3 |
| 10 | Comparison of CO 2 emission scenarios and mitigation opportunities in China’s five sectors in 2020显示文摘 | Wenjia Cai Can Wang Jining Chen Ke Wang Ying Zhang Xuedu Lu | 2008 | Energy Policy2008，，3： | 3 |
| 11 | Decomposition of energy-related CO 2 emission in China: 1957–2000显示文摘 | Can Wang Jining Chen Ji Zou | 2004 | Energy2004，，1： | 2 |
| 12 | Modeling of nitrobenzene in the river with ice process in high-latitude regions显示文摘To deal with the accidental release of pollutants into frozen rivers, those rivers in high-latitude regions should be treated differently. Pollutants could be stored up in the ice and released when the ice melts in spring, perhaps resulting in secondary pollution in the river. A water quality model of nitrobenzene has been developed in this paper to assess the influence on river water quality due to the freezing process. The model is made up of three modules: thermodynamic module, hydrodynamic module and water quality module. The thermodynamic module considers the complex heat exchange processes between the water body and the atmosphere, the water body and the river bed, the water body and the ice cover, and so on. The growth of the ice cover is simulated in a simplified form whilst taking consideration of heat balance. The hydrodynamic model uses the Saint-Venant equations in non-constant flow and the influence of the ice cover is measured. The degradation, diffusion, absorption and desorption, and the influence of the freezing process are incorporated in the water quality module and the concept of Con- tinuously Stirred Tanked Reactors (CSTRs) model is applied in the model construction. The model has been applied to supporting the management of accidental pollution in the Songhua River. The model was calibrated and validated with monitored data. Regional sensitivity analysis based on a task-based Hornberger-Spear-Young (HSY) algorithm was carried out to examine the model structure and the re- sult showed that the model could describe the system very well. Then the conditioned model was ap- plied to predicting the concentration of nitrobenzene in the water when the ice melted in spring. The predictive result showed that the release of pollutants in the ice could lead to an increase in the con- centration of pollutants in the water, but the increase would be very small because there was only a small amount of pollutants stored in the ice. A secondary pollution could therefore be avoided. Also, with necessary modifications, the model established in this study could be applied to the water quality management in rivers that freeze in winter. | SUN PengCheng ZENG SiYu CHEN JiNing | 2009 | Science China Earth Sciences2009，52，3： | 2 |
| 13 | Lipid-lowering effects of oleanolic acid in hyperlipidemic patients显示文摘Oleanolic acid(OA) is a pentacyclic triterpenoid compound extracted from olea europaeal, a traditional Chinese medicine herb. OA has been used in the clinic as a hepatoprotective medicine in China since 1970 s. In our previous study, we observed that OA could ameliorate hyperlipidemia in animal models. In the present study, we conducted a small-scale clinical trial to evaluate the hypolipidemia effect of OA in hyperlipidemic patients. Hyperlipidemic patients were administrated with OA for four weeks(4 tablets once, three times a day). The blood samples of the patients were collected before and after OA treatment. The biological parameters were measured. Furthermore, three patients' blood samples were studied with DNA microarray. After OA administration, the TC, TG, and HDLC levels in serum decreased significantly. DNA microarray analysis results showed that the expressions of 21 m RNAs were significantly changed after OA treatment. Bioinformatics analysis showed 17 m RNAs were up-regulated and 4 m RNAs were down-regulated significantly after OA treatment. Five m RNAs(CACNA1 B, FCN, STEAP3, AMPH, and NR6 A1) were selected to validate the expression levels by q RT-PCR. Therefore, OA administration differentially regulated the expression of genes involved in lipid metabolism. The data showed a clinical evidence that OA could improve hyperlipidemia and also unveiled a new insight into the molecular mechanisms underlying the pharmacological effect of OA on hyperlipidemia. | LUO Han-Qiong SHEN Jie CHEN Cai-Ping MA Xiao LIN Chao OUYANG Qiong XUAN Chun-Xiao LIU Jine SUN Hong-Bin LIU Jun | 2018 | Chinese Journal of Natural Medicines2018，16，5： | 2 |
| 14 | Scenario analysis on CO 2 emissions reduction potential in China’s iron and steel industry显示文摘 | Ke Wang Can Wang Xuedu Lu Jining Chen | 2006 | Energy Policy2006，，4： | 2 |
| 15 | A cost-benefit analysis for the economic growth in China 显示文摘 | Wen Zongguo Chen Jining | 2008 | Ecological Economics2008，65，2： | 1 |
| 16 | Decomposition of energy- related CO2 emission in China: 1957 - 2000 显示文摘 | Can Wang Jining Chen Ji Zou | 2005 | Energy2005 (30) : 73 - 832005，2005，30： | 1 |
| 17 | Assessment of policy alternatives and key technologies for energy conservation and water pollution reduction in China’s synthetic ammonia industry显示文摘 | Chao Zhang Jining Chen Zongguo Wen | 2011 | Journal of Cleaner Production2011，，： | 1 |
| 18 | Decomposition of energy-re- lated CO2 emission in China: 1957-2000 显示文摘 | WANG Can CHEN Jining ZOU Ji | 2005 | Energy2005，，30： | 1 |
| 19 | Regional Industrial Production's Spatial Distribution and Water Pollution Control: A Plant Level Aggregation Method for the Case of A Small Region in China 显示文摘 | Zhao Nan Liu Yi Chen Jining | 2009 | Science of the Total Environment2009，407，17： | 1 |
| 20 | Decomposition of energy- related CO2 emission in China : 1957- 2000 显示文摘 | WANG Can CHEN Jining ZOU Ji | 2005 | Energy2005，30，1： | 1 |
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