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| 1 | Piperlongumine Inhibits Zika Virus Replication In vitro and Promotes Up-Regulation of HO-1 Expression, Suggesting An Implication of Oxidative Stress显示文摘Owing to the widespread distribution of mosquitoes capable of transmitting Zika virus, lack of clinical vaccines and treatments, and poor immunity of populations to new infectious diseases, Zika virus has become a global public health concern. Recent studies have found that Zika virus can continuously infect human brain microvascular endothelial cells.These cells are the primary components of the blood–brain barrier of the cerebral cortex, and further infection of brain tissue may cause severe damage such as encephalitis and fetal pituitary disease. The present study found that a biologically active base, piperlongumine(PL), inhibited Zika virus replication in human brain microvascular endothelial cells, Vero cells, and human umbilical vein endothelial cells. PL also significantly increased heme oxygenase-1(HO-1) gene expression, while silencing HO-1 expression and using the reactive oxygen species scavenger, N-acetylcysteine, attenuated the inhibitory effect of PL on Zika virus replication. These results suggest that PL induces oxidative stress in cells by increasing reactive oxygen species. This, in turn, induces an increase in HO-1 expression, thereby inhibiting Zika virus replication. These findings provide novel clues for drug research on the prevention and treatment of Zika virus. | Weizhi Lu Linjuan Shi Jing Gao Huimin Zhu Ying Hua Jintai Cai Xianbo Wu Chengsong Wan Wei Zhao Bao Zhang | 2021 | Virologica Sinica2021，36，3： | 4 |
| 2 | Environmental taxation and regional inequality in China显示文摘In order to combat environmental pollution, China enacted the Environmental Protection Tax Law in early 2018. Yet the impacts of the environmental tax on individual regions with different socioeconomic statuses, which are crucial for social justice and public acceptance, remain unclear. Based on a MultiRegional Input-Output(MRIO) table and a nationally regulated tax payment calculation method, this study analyzes the distributional impacts of an environmental tax based upon province’s consumption from both inter-provincial and rural-urban aspects. The national tax revenue based on the current levy mechanism is estimated to be only one seventh of the economic loss from premature mortality caused by ambient particulate matter(PM2.5). The taxation may slightly alleviate urban-rural inequality but may not be helpful with reducing inter-provincial inequality. We further analyze two alternative levy mechanisms. If each province imposes taxes to products it consumes(rather than produces, as in the current mechanism), with the tax rate linearly dependent on its per capita consumption expenditure, this would moderately increase the national tax revenue and significantly reduce inter-provincial inequality.To better compensate for the economic costs of air pollution and reduce regional inequality, it would be beneficial to increase the tax rate nationwide and implement a levy mechanism based on provincially differentiated levels of consumption and economic status. | Jingxu Wang Jintai Lin Kuishuang Feng Peng Liu Mingxi Du Ruijing Ni Lulu Chen Hao Kong Hongjian Weng Mengyao Liu Giovanni Baiocchi Yu Zhao Zhifu Mi Jing Cao Klaus Hubacek | 2019 | Science Bulletin2019，64，22： | 3 |
| 3 | Stratospheric Ozone-induced Cloud Radiative Effects on Antarctic Sea Ice显示文摘Recent studies demonstrate that the Antarctic Ozone Hole has important influences on Antarctic sea ice.While most of these works have focused on effects associated with atmospheric and oceanic dynamic processes caused by stratospheric ozone changes,here we show that stratospheric ozone-induced cloud radiative effects also play important roles in causing changes in Antarctic sea ice.Our simulations demonstrate that the recovery of the Antarctic Ozone Hole causes decreases in clouds over Southern Hemisphere(SH)high latitudes and increases in clouds over the SH extratropics.The decrease in clouds leads to a reduction in downward infrared radiation,especially in austral autumn.This results in cooling of the Southern Ocean surface and increasing Antarctic sea ice.Surface cooling also involves ice-albedo feedback.Increasing sea ice reflects solar radiation and causes further cooling and more increases in Antarctic sea ice. | Yan XIA Yongyun HU Jiping LIU Yi HUANG Fei XIE Jintai LIN | 2020 | Advances in Atmospheric Sciences2020，37，5： | 3 |
| 4 | Dynamic characteristics of the out-of-plane vibration for an axially moving membrane 显示文摘 | Shin Changho Chung Jintai Kim Wonsuk | 2005 | Journal of Sound and Vibration2005，286，： | 1 |
| 5 | Dynamic Responses of the In-plane and Out-of-plane Vibrations for an Axially Moving Membrane显示文摘 | Changho S Jintai C Hong H Y | 2006 | Journal of Sound and Vibration2006，297，2： | 1 |
| 6 | Dynamic responses of the inplane and out-of-plane vibrations for an axially moving membrane显示文摘 | Changho S Jintai C Hong H Y | 2006 | Journal of Sound and Vibration2006，297，2： | 1 |
| 7 | Inverting square systems algebraically is exponential 显示文摘 | DING Jintai CLOUGH C ARAUJO R | 2014 | Finite Fields and Their Applications2014，26，： | 1 |
| 8 | Case history:Noise source identification of an automobile alternator by rpm dependent noise and vibration spectrum analysis显示文摘 | Sang Joon Suh Jintai Chung Byung Duk Lim | 1991 | Noise Control Engineers Journal1991，37，1： | 1 |
| 9 | Dynamic responses of the in-plane and out-of-plane vibrations for an axially moving membrane 显示文摘 | Changho S Jintai C Hong H Y | 2006 | Journal of Sound and Vibration2006，297，2： | 1 |
| 10 | Dynamic characteristics of the out-of-plane vibration for an axially moving membrane显示文摘 | Changbo Shin Jintai Chung Wonsuk Kim | 2005 | Journal of Sound and Vibration2005，286，： | 1 |
| 11 | Multivariable Public Key Cryptosystem 显示文摘 | Jintai Ding Dieter Schmit | 2006 | Contemporary Mathematics2006，419，： | 1 |
| 12 | Dynamic responses of the in-plane and out-of-plane vibrations for an axially moving membrane显示文摘 | Changho Shina Jintai Chung Hong Hee Yoo | 2006 | Journal of Sound and Vibration2006，297，： | 1 |
| 13 | Dynamic analysis for a planetary gear with time-varying pressure angles and contact ratios显示文摘 | Woohyung Kim Ji Yeong Lee Jintai Chung | 2012 | Journal of Sound and Vibration2012，331，4： | 1 |
| 14 | New fluid velocity expression in an extensible semi-circular pipe conveying fluid显示文摘 | Duhan Jung Jintai Chung Hong Hee Yoo | 2007 | Journal of Sound and Vibration2007，，1： | 1 |
| 15 | Free in-plane vibration of an axially moving membrane显示文摘 | Shin C H Wonsuk Kim Jintai Chung | 2004 | Journal of Sound and Vibration2004，272，12： | 1 |
| 16 | Dynamic model for free vibration and response analysis of rotating beams显示文摘 | Hyungrae Kim Hong Hee Yoo Jintai Chung | 2013 | Journal of Sound and Vibration2013，，： | 1 |
| 17 | Dynamic analysis for a planetary gear with time-varying pressure angles and contact ratios显示文摘 | Woohyung Kim Ji Yeong Lee Jintai Chung | 2011 | Journal of Sound and Vibration2011，，4： | 1 |
| 18 | Immune Response, Safety, and Survival and Quality of Life Outcomes for Advanced Colorectal Cancer Patients Treated with Dendritic Cell Vaccine and Cytokine-Induced Killer Cell Therapy显示文摘 | Hui Zhu Xuejing Yang Jiali Li Yanjie Ren Tianyu Zhang Chunze Zhang Jintai Zhang Jing Li Yan Pang Shiwu Zhang | 2014 | BioMed Research International2014，，： | 1 |
| 19 | New fluid velocity expression in an extensible semi-circular pipe conveying fluid 显示文摘 | Jung Duhan Chung Jintai Yoo H H | 2007 | Journal of Sound and Vibration2007，304，： | 1 |
| 20 | Recent changes in particulate air pollution over China observed from space and the ground: effectiveness of emission control显示文摘 | LIN Jintai NIELSEN C ZHAO Yu | 2010 | Environ Sci Technol2010，44，： | 1 |
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