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| 1 | Introduction of a multicenter online database for non-metastatic breast cancer in China显示文摘Dear Editor,Breast cancer is now the most frequently diagnosed cancer and is the fifth leading cause of cancer-related death in Chinese women. Therefore, the burden of breast cancer in China is gradually increasing. According to figures released by the Chinese Cancer Center in 2018, the number of newly diagnostic breast cancer is about 278,900 cases, accounting for 16.51%of all women who were diagnosed with the first primary malignant tumors;and 66,000 cases of breast cancer died in 2014 (Chen et al., 2016). | Yaping Yang Jieqiong Liu Min Peng Fengxi Su Xiaoming Xie Zhenzhen Liu Jundong Wu Wei Wei Dongxian Zhou Weiwen Li Ailing Zhang Guosen Su Weixiong Yang Jishang Chen Dekui Ma Yongguang Cai Kai Chen Liling Zhu Qiang Liu Erwei Song | 2020 | Science China(Life Sciences)2020，63，9： | 4 |
| 2 | A Field Investigation on the Effects of Background Erosion on the Free Span Development of a Submarine Pipeline显示文摘The safety of submarine pipelines is largely influenced by free spans and corrosions. Previous studies on free spans caused by seabed scours are mainly based on the stable environment, where the background seabed scour is in equilibrium and the soil is homogeneous. To study the effects of background erosion on the free span development of subsea pipelines, a submarine pipeline located at the abandoned Yellow River subaqueous delta lobe was investigated with an integrated surveying system which included a Multibeam bathymetric system, a dual-frequency side-scan sonar, a high resolution sub-bottom profiler, and a Magnetic Flux Leakage(MFL) sensor. We found that seabed homogeneity has a great influence on the free span development of the pipeline. More specifically, for homogeneous background scours, the morphology of scour hole below the pipeline is quite similar to that without the background scour, whereas for inhomogeneous background scour, the nature of spanning is mainly dependent on the evolution of seabed morphology near the pipeline. Magnetic Flux Leakage(MFL) detection results also reveal the possible connection between long free spans and accelerated corrosion of the pipeline. | WEN Shipeng XU Jishang HU Guanghai DONG Ping SHEN Hong | 2015 | Journal of Ocean University of China2015，14，4： | 4 |
| 3 | Calculation of Maximum Allowable Free Span Length and Safety Assessment of the DF1-1 Submarine Pipeline显示文摘The DF1-1 submarine pipeline was investigated using a dual-frequency side-scan sonar and a swath sounder system.More than a hundred scour pits under the pipeline were found,most of which have caused the span of the pipeline to increase and threatened its safety.The maximum allowable free span length (MAFSL) of the pipeline was determined through the limitations regarding maximum allowable stress under static or quasi-static loads and the onset of Vortex Induced Vibrations (VIV) under different hydrodynamic actions.The results show that the MAFSL under static conditions is 56 m.However,the MAFSLs are 30 m and 20 m under ordinary weather conditions and hurricane-induced currents for the 100-year return period,respectively,to avoid VIV as calculated by using the highest safety class factor.It is suggested that spanning pipelines longer than 20 m should be supported.Additionally,eight successive spans which may also threaten the pipeline were proposed.The most hazardous scour pits are along the pipeline section from KP42 to KP51. | XU Jishang LI Guangxue Juan J. Horrillo YANG Rongmin CAO Lihua | 2010 | Journal of Ocean University of China2010，9，1： | 4 |
| 4 | Responses of Yellow Sea Cold Water Mass to Typhoon Bolaven显示文摘A two-month seabed-mounted observation(YSG1 area) was carried out in the western Yellow Sea Cold Water Mass(YSCWM) using an RDI-300 K acoustic Doppler current profiler(ADCP) placed at a water depth of 38 m in late summer, 2012. On August 2012, Typhoon Bolaven passed east of YSG1 with a maximum wind speed of 20 m s-1. The water depth, bottom temperature, and profile current velocities(including u, v and w components) were measured, and the results showed that the typhoon could induce horizontal current with speed greater than 70 cm s-1 in the water column, which is especially rare at below 20 meters above bottom(mab). The deepening velocity shear layer had an intense shear velocity of around 10 cm s-1 m-1, which indicated the deepening of the upper mixed layer. In the upper water column(above 20 mab), westward de-tide current with velocity greater than 30 cm s-1 was generated with the typhoon's onshore surge, and the direction of current movement shifted to become southward. In the lower water column, a possible pattern of eastward compensation current and delayed typhoon-driven current was demonstrated. During the typhoon, bottom temperature variation was changed into diurnal pattern because of the combined influence of typhoon and tidal current. The passage of Bolaven greatly intensified local sediment resuspension in the bottom layer. In addition, low-density particles constituted the suspended particulate matter(SPM) around 10 mab, which may be transported from the central South Yellow Sea by the typhoon. Overall, the intensive external force of the Typhoon Bolaven did not completely destroy the local thermocline, and most re-suspended sediments during the typhoon were restricted within the YSCWM. | LI Jianchao LI Guangxue XU Jishang QIAO Lulu MA Yanyan DING Dong LIU Shidong | 2019 | Journal of Ocean University of China2019，18，1： | 3 |
| 5 | The Marine Dynamics and Changing Trend off the Modern Yellow River Mouth显示文摘Topography around the Yellow River mouth has changed greatly in recent years, but studies on the current state of ma- rine dynamics off the Yellow River mouth are relatively scarce. This paper uses a two-dimension numerical model(MIKE 21) to reveal the tidal and wave dynamics in 2012, and conducts comparative analysis of the changes from 1996 to 2012. The results show that M2 amphidromic point moved southeastward by 11 km. It further reveals that the tides around the Yellow River mouth are relatively stable due to the small variations in the tidal constituents. Over the study period, there is no noticeable change in the distribution of tidal types and tidal range, and the mean tidal range off the river mouth during the period studied is 0.5–1.1 m. However, the tidal currents changed greatly due to large change in topography. It is observed that the area with strong tidal currents shifted from the old river mouth(1976–1996) to the modern river mouth(1996–present). While the tidal current speeds decreased continually off the old river mouth, they increased off the modern river mouth. The Maximum Tidal Current Speed(MTCS) reached 1.4 m s-1, and the maximum current speed of 50-year return period reached 2.8 m s-1. Waves also changed greatly due to change in topography. The significant wave height(H1/3) of 50-year return period changed proportionately with the water depth, and the ratio of H1/3 to depth being 0.4–0.6. H1/3 of the 50-year return period in erosion zone increased continually with increasing water depth, and the rate of change varied between 0.06 and 0.07 m yr-1. Based on the results of this study, we infer that in the future, the modern river mouth will protrude gradually northward, while the erosion zone, comprising the old river mouth and area between the modern river mouth and the old river mouth(Intermediate region) will continue to erode. As the modern river mouth protrudes towards the sea, there will be a gradual increase in the current speed and decrease in wave height. Conversely, the old river mouth will retreat, with gradual decrease in current speed and increase in wave height. As more coastal constructions spring up around the Yellow River mouth in the future, we recommend that variation in hydrodynamics over time should be taken into consideration when designing such coastal constructions. | WANG Nan LI Guangxue XU Jishang QIAO Lulu DADA Olusegun A. ZHOU Chunyan | 2015 | Journal of Ocean University of China2015，14，3： | 3 |
| 6 | The spatio-temporal invariability of sediment concentration and the flow–sediment relationship for hilly areas of the Chinese Loess Plateau显示文摘 | Mingguo Zheng Fen Qin Jishang Yang Qiangguo Cai | 2013 | Catena2013，，： | 2 |
| 7 | The spatio- temporal invariability of sediment concentration and the flow- sediment relationship for hilly areas of the Chinese Loess Plateau显示文摘 | Zheng Mingguo Qin Fen Yang Jishang | 2013 | Catena2013，109，： | 1 |
| 8 | Source Evolution and Its Relationship to Climate Change Since the Middle–Late Pleistocene in Laizhou Bay, China显示文摘Through the geochemical analysis of two hundred-meters cores KD4 and ZK3 from Laizhou Bay,in this study,we determined the distribution law and controlling factors of the geochemical elements.We analyzed 24 elements with respect to their R factors and major principal components,which were combined with the source discrimination functions DFCr/Th and DFCa/Al to obtain the sediment source index and its variation with depth for this area.A comparison of the changes in climate indicators suggests a clear correlation between the source and climate changes.The results show that the Yellow River and surrounding short-term rivers are the main sediment sources in this area.The PC3 of the KD4 core and PC2 of the ZK3 core(e.g.,CaO,MnO,SiO2)exhibit significant variations and reflect the relative contributions of Yellow River sources.The deposition process can be divided into six stages:in Phase I(MIS 5c–MIS 5a),the Yellow River formed,and the composition of the Yellow River had a greater influence on the sedimentary composition of the study area.In Phase II(MIS 5a–MIS 3),the sediment sources of the Yellow River and the short-term streams in this area were wavering,with the sediments derived from short-term rivers playing a more important role.In Phase III(MIS 3),with a sharp drop in temperature,the study area was in the process of retreat,and the sediment source changed from the Yellow River to short-term rivers,after which the Yellow River source material remained the main sediment source for the region.A similar process occurred three more times in Phase IV(MIS 3–MIS 2),Phase V(MIS 2–MIS 1),and Phase VI(MIS 1).With changes in climate,especially during alternating sea-land phases,the sediment source varied in marine-terrestrial-marine phases,and the changes are observed as Yellow River source-surrounding provenance-Yellow River source.However,this process of change is not synchronized with the sea-land strata alternation. | GONG Chuanzhang LI Guangxue LIU Yong DING Dong XU Jishang MA Yanyan QIAO Lulu and WANG Haoyin | 2020 | Journal of Ocean University of China2020，19，1： | 1 |
| 9 | Seasonal Suspended Particles Distribution Patterns in Western South Yellow Sea Based on Acoustic Doppler Current Profiler Observation显示文摘An Acoustic Doppler Current Profiler(ADCP) observation site was set up in the Western South Yellow Sea from 2012 to 2013 to study the local suspended particle matters(SPM) distribution pattern. The SPM concentration could be semi-quantitatively represented by backscatter intensity(Sv), converted by the echo intensity(EI) of ADCP. Results show two types of SPM in the water column: the quasi-biological SPM and quasi-mineral SPM. The quasi-biological SPM mainly exists in summer half year and is concentrated above the thermocline. It has periodically diurnal variations with high concentration at night and low concentration in the daytime. The quasi-mineral SPM is located in lower part of the water column, with similar relation to monthly tidal current variation all year round. However, the daily quasi-mineral SPM distribution patterns vary between summer and winter half year. The sunlight is thought to be the origin factor leading to the diurnally vertical motion of the biological features, which might cause the diurnal Sv variation. Unlike in winter half year when tidal current is relatively single driving force of the monthly SPM pattern, the high speed current near the thermocline is also responsible for the concentration of quasi-mineral SPM in summer half year. The sediment input difference between summer and winter half year contribute to the varied daily variation of quasi-mineral SPM with re-suspended SPM in winter and sediments from Yellow Sea Mud Area(YSMA) in summer. The seasonal variations in hydrodynamics, water structure and heavy-wind incidents are the primary factors influencing the differential seasonal SPM distribution patterns. | LI Jianchao LI Guangxue XU Jishang QIAO Lulu DONG Ping DING Dong LIU Shidong SUN Pingkuo | 2015 | Journal of Ocean University of China2015，14，3： | 1 |
| 10 | Estimation of Extreme Marine Hydrodynamic Variables in Western Laizhou Bay显示文摘Laizhou Bay and its adjacent waters are of great importance to China's marine oil and gas development. It is therefore crucial to estimate return-period values of marine environmental variables in this region to ensure the safety and success of maritime engineering and maritime exploration. In this study, we used numerical simulations to estimate extreme wave height, sea current velocity and sea-level height in western Laizhou Bay. The results show that the sea-level rise starts at the mouth of the bay, increases toward west/southwest, and reaches its maximum in the deepest basin of the bay. The 100-year return-period values of sea level rise can reach 3.4–4.0 m in the western bay. The elevation of the western part of the Qingdong Oil Field would remain above the sea surface during extreme low sea level, while the rest of the oil field would be 1.6–2.4 m below the sea surface. The return-period value of wave height is strongly affected by water depth; in fact, its spatial distribution is similar to the isobath's. The 100-year return-period values of effective wave height can be 6 m or higher in the central bay and be more than 1 m in the shallow water near shore. The 100-year return-period values of current velocity is about 1.2–1.8 m s-1 in the Qingdong Oil Field. These results provide scientific basis for ensuring construction safety and reducing construction cost. | DAI Yanchen QIAO Lulu XU Jishang ZHOU Chunyan DING Dong BI Wei | 2015 | Journal of Ocean University of China2015，14，3： | 1 |
| 11 | Evolution of Palaeoenvironment of the South Yellow Sea Since the Last Deglaciation显示文摘The sediments in core YS01 recovered from the South Yellow Sea mud deposit zone contain abundant benthic foraminifera,particularly shallow continental shelf species,but rare of planktonic foraminifera.The benthic foraminifera are dominated by stenohaline cold shallow-water species and euryhaline brackish-water species.In this paper,the palaeoenvironmental changes were discussed based on the grain-size compositions and benthic foraminiferal assemblages.Six different benthic foraminiferal assemblages were discriminated by species analysis from the foraminiferal fauna.According to AMS14C dating data in core YS01,we identified four main stages of marine environmental changes since the last deglaciation:a near-shore depositional stage(13.1–9.5 kyr B.P.),a transitional stage from near-shore deposition to shallow-sea deposition(9.5–5.6 kyr B.P.),a high sea level stage with shallow-sea deposition(5.6–2.9 kyr B.P.),and a stable shallow-sea depositional stage(2.9 kyr B.P.to the present). | WANG Haoyin LI Guangxue ZHANG Yang LIU Yong LIU Dongsheng DING Dong XU Jishang MA Yanyan QIAO Lulu WANG Liyan LI Qian | 2020 | Journal of Ocean University of China2020，19，4： | 0 |
| 12 | Sedimentary Characteristics of the Second Marine Layer During the Late Marine Isotope Stage 3 in Southern Yellow Sea and Their Response to the East Asian Monsoon显示文摘We use the particle size of sediments in core YS01 A to study the sedimentary environment of the mud deposit in the central South Yellow Sea of China during late Marine Isotope Stages 3(MIS3;40.5 kyr–31.3 kyr).In addition,the East Asian Monsoon and its relationship with the North Atlantic Ocean climate change are discussed based on the sensitive grain-size calculation and the spectrum analysis.The results show that during late MIS3,the muddy area in the central South Yellow Sea experienced the evolution of coastal facies,shallow marine facies,coastal facies,and continental facies,with weak hydrodynamic conditions.Compared with other climate indicators,we found that there were many century to millennium-scale climate signals documented in the muddy area sediments in the central South Yellow Sea.According to our particle size results,three strong winter monsoon events occurred at 37.6 kyr,35.6 kyr and 32.2 kyr.The East Asian Winter Monsoon records in core YS01 A are consistent with the Greenland ice core and the Hulu cave stalagmite δ^(18)O.The millennial and centennial scale cycles,which are 55 yr,72 yr,115 yr,262 yr respectively,correspond to solar activity cycles,while the 1049 yr and 2941 yr cycles correspond to the Dansgaard-Oeschger cycles.These cycles indicate that the paleoclimate evolution of the area was controlled by the solar activities,with the high-latitude driving thermohaline circulation as the main energy conveyor belt,followed by the sea-air-land amplification of the winter monsoon variation in the central Yellow Sea in the late MIS3. | ZHANG Yang LI Guangxue GUO Hongzhou LIU Yong WANG Haoyin XU Jishang DING Dong QIAO Lulu MA Yanyan WANG Liyan LI Qian | 2018 | Journal of Ocean University of China2018，17，5： | 0 |
| 13 | Preparation of Polyclonal Antisera of Dairy Cow S100A12 Protein显示文摘[Objective] This study aimed to prepare dairy cow anti-S100A12 antisera and develop a highly effective and sensitive immunological detection reagent for further investigation of the functions of dairy cow S100A12.[Method] Purified S100A12 protein was respectively emulsified with Freund's complete adjuvant and Freund's incomplete adjuvant as the antigen for immunizing New Zealand white rabbits to prepare the polyclonal antisera.The titer was detected using agar double diffusion assay and indirect enzyme-linked immunosorbent assay (ELISA) and the specificity was determined with Western Blot.[Result] The titer of anti-S100A12 antisera was 1∶8 as determined by agar double diffusion assay and over 1∶409 600 by ELISA.Western Blot result showed that the polyclonal antisera could be specifically combined with S100A12 protein.[Conclusion] The results indicated that anti-S100A12 polyclonal antibody with high titer and high specificity was successfully obtained, which provided a novel tool for further investigation of the functions of S100A12 gene. | Suizhong CAO Yafei CUI Xueping YAO Kang YONG Jishang LI Shumin YU | 2013 | Agricultural Biotechnology2013，2，3： | 0 |
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