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| 1 | Sentinel lymph node biopsy in clinically detected ductal carcinoma in situ显示文摘AIM:To study the indications for sentinel lymph node biopsy(SLNB) in clinically-detected ductal carcinoma in situ(CD-DCIS).METHODS:A retrospective analysis of 20 patients with an initial diagnosis of pure DCIS by an image-guided core needle biopsy(CNB) between June 2006 and June 2012 was conducted at King Faisal Specialist Hospital.The accuracy of performing SLNB in CD-DCIS,the rate of sentinel and non-sentinel nodal metastasis,and the histologic underestimation rate of invasive cancer at initial diagnosis were analyzed.The inclusion criteria were a preoperative diagnosis of pure DCIS with no evidence of invasion.We excluded any patient with evidence of microinvasion or invasion.There were two cases of mammographically detected DCIS and 18 cases of CDDCIS.All our patients were diagnosed by an imageguided CNB except two patients who were diagnosed by fine needle aspiration(FNA).All patients underwent breast surgery,SLNB,and axillary lymph node dissection(ALND) if the SLN was positive.RESULTS:Twenty patients with an initial diagnosis of pure DCIS underwent SLNB,2 of whom had an ALND.The mean age of the patients was 49.7 years(range,35-70).Twelve patients(60%) were premenopausal and 8(40%) were postmenopausal.CNB was the diagnostic procedure for 18 patients,and 2 who were diagnosed by FNA were excluded from the calculation of the underestimation rate.Two out of 20 had a positive SLNB and underwent an ALND and neither had additional non sentinel lymph node metastasis.Both the sentinel visualization rate and the intraoperative sentinel identification rate were 100%.The false negative rate was 0%.Only 2 patients had a positive SLNB(10%) and neither had additional metastasis following an ALND.After definitive surgery,3 patients were upstaged to invasive ductal carcinoma(3/18 = 16.6%) and 3 other patients were upstaged to DCIS with microinvasion(3/18 = 16.6%).Therefore the histologic underestimation rate of invasive disease was 33%.CONCLUSION:SLNB in CD-DCIS is technically feasible and highly accurate.We recommend limiting SLNB to patients undergoing a mastectomy. | Ahmed Yahia Al-Ameer Sahar Al Nefaie Badria Al Johani Ihab Anwar Taher Al Tweigeri Asma Tulbah Mohmmed Alshabanah Osama Al Malik | 2016 | World Journal of Clinical Oncology2016，7，2： | 3 |
| 2 | Determination of functional fitness age in women aged 50 and older显示文摘Background: The construction of useful and attainable indicators of fitness assessment deserves special attention in clinical practice. We aimed to construct an indicator of the functional fitness age(FFA) of women aged 50 and older by an equation using fitness outcomes and its correlation with chronological age(CA) and to analyze the external validity of our results by comparing our sample to others.Methods: Participants(n=459, age: 70.3 ± 7.9 years, mean ± SD) were evaluated using the Senior Fitness Test battery. We applied a multiple regression and a subsequent Holt's exponential smoothing to analyze the outcomes.Results: We obtained a statistically significant expression of F(6, 452) = 328.384; p < 0.0005 in which the coefficients of the equation explain81% of variability(R_(corrected)~2 = 0.813). The equation correlates fitness assessment in women aged 50 and over with regards to CA:FFA = 40.146 + 0.350 X CS(stand)-0.714 X AC(rep)-0.110 X ST(step)-0.177 X CSR(cm)-0.101 X BS(cm) + 8.835 X FUG(s) where CS means chair stand test, AC. means arm curl test, ST means 2-min step test, CSR means chair sit-and-reach test, BS means back scratch test, FUG means 8-foot up-and-go test. We compared this index with percentiles distribution from our sample and from other studies.Conclusion: We suggest the use of FFA as a valid indicator of fitness in adult and senior women as well as a useful motivational tool to undertake exercise programs. | Edgar Johani Latorre-Rojas Joan Antoni Prat-Subirana Xavier Peirau-Terés Sebastià Mas-Alòs José Vicente Beltrán-Garrido Antoni Planas-Anzano | 2019 | Journal of Sport and Health Science2019，8，3： | 2 |
| 3 | Orofacial granulomatosis: Clinical features and long-term outcome of therapy 显示文摘 | Johani KA Moles DR Hodgson TA | 2010 | J Am Acad Dermatol2010，62，： | 1 |
| 4 | Multi-drug carbapenem-resistant Klebsiella pneumoniae infection carrying the OXA-48 gene and showing variations in outer membrane protein 36 causing an outbreak in a tertiary care hospital in Riyadh, Saudi Arabia显示文摘 | Zaman UZ Aldrees M AL Johani SM | 2014 | Int J Infect Dis2014，28，： | 1 |
| 5 | Prevalence of antimicrobial resistance among gram-negative isolates in an adult intensive care unit at a tertiary care center in Saudi Arabia显示文摘 | Al Johani SM Akhter J Balkhy H | | 0，，05： | 1 |
| 6 | Targeting frameshifting in the human immunodeficiency virus显示文摘 | Léa Brakier-Gingras Johanie Charbonneau Samuel E Butcher | 2012 | Expert Opinion on Therapeutic Targets2012，，3： | 1 |
| 7 | Calcineurin inhibitors in oral medicine显示文摘 | AL JOHANI K A HEGARTY A M PORTER S R | 2009 | J Am Acad Dermatol2009，61，5： | 1 |
| 8 | Calcineurin inhibitors in oral medicine显示文摘 | AI Johani KA Hegarty AM Porter SR | 2009 | J Am Acad Dermatol2009，61，5： | 1 |
| 9 | Randomized trial of ligation versus combined ligation and sclerotherapy for bleeding esophageal varices显示文摘 | Ibrahim Al Traif Fayiz Sbeih Fachartz Abdulrahman Al Jumah Mishall Al Johani Ahmed Al Omair Fahad Al Bakr Bandar Al Knawy Ahmed El Hafi Mohammed H. Khan | 1999 | Gastrointestinal Endoscopy1999，，1： | 1 |
| 10 | Maternal and neo- natal risk factors for early-onset group B streptococcal disease: a case control study 显示文摘 | AI-Kadri HM Bamuhair SS Johani SM | 2013 | Int J Women Health2013，5，： | 1 |
| 11 | Prevalence of antimicrobial resistance among gram-negative isolates in an adult intensive care unit at a tertiary care center in Saudi Arabia显示文摘 | A1 Johani S M Akhter J Balkhy H | 2010 | Ann Saudi Med2010，30，5： | 1 |
| 12 | Genetic diversity of OXA - 51 - like genes among muhidrug - resistant Acinetobacter bau- mannii in Riyadh, Saudi Arabia 显示文摘 | Aly M Tayeb HT A1 Johani SM | 2014 | European journal of clinical mi- crobiology & infectious diseases : official publication of the European Society of Clinical Microbiology2014，33，7： | 1 |
| 13 | Self - management prac- tices among type 2 diabetes patients attending primary health - care centres in Medina, Saudi Arabia显示文摘 | A1 Johani KA Kendall GE Snider PD | 2015 | East Mediterr Health J2015，21，9： | 1 |
| 14 | Prevalence of an- timicrobial resistance among gram-negative isolates in an a- dult intensive care unit at a tertiary care center in Saudi Ara- bia显示文摘 | A1 Johani SM Akhter J Balkhy H etal | 2010 | Ann Saudi Med2010，30，5： | 1 |
| 15 | Prevalence of antimicrobial resistance among gram-negative isolates in an adult intensive care unit at a tertiary care center in Saudi Arabia显示文摘 | Johani S Akhter J Balkhy H | 2010 | Ann Saudi Med2010，30，5： | 1 |
| 16 | Genetic diversity of OXA-51-like genes among multidrugresistant Acinetobacter baumannii in Riyadh,Saudi Arabia显示文摘 | Aly M Tayeb HT Al Johani SM | 2014 | Eur J Clin Microbiol Infect Dis2014，33，7： | 1 |
| 17 | Orofaeial granu- lomatosis: Clinical features and long-term outcome of therapy显示文摘 | A1 Johani KA Moles DR Hodgson TA | 2010 | J Am Acad Dermatol2010，62，4： | 1 |
| 18 | Orofacial granulomatosis: Clinical features and long-term outcome of therapy显示文摘 | Khalid A. Al Johani David R. Moles Tim A. Hodgson Stephen R. Porter Stefano Fedele | 2009 | Journal of the American Academy of Dermatology2009，，4： | 1 |
| 19 | Maternal and neonatal risk factors for early-onset group B streptococcal disease:a case control study显示文摘 | Al-Kadri HM Bamuhair SS Johani SM | 2013 | Int J Womens Health2013，5，： | 1 |
| 20 | Genetic diversity of OXA-51-like genes among multidrug-resistant Acinetobacter baumannii in Riyadh,Saudi Arabia显示文摘 | Aly M Tayeb HT Al Johani SM | 2014 | Eur J Clin Microbiol Infect Dis2014，33，7： | 1 |
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