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| 1 | Liver iron transport显示文摘肝在铁新陈代谢起一个中央作用。它是为铁的主要存储地点并且也表示涉及铁运输和铁动态平衡的规定的分子的一个复杂范围。与肝的铁运输或规定联系的越来越多的基因被识别了。这些包括转铁蛋白受体(TFR1 并且 2 ) , ferrireductase (STEAP3 ) ,运输 ers 二价的金属 transporter-1 (DMT1 ) 和象 haemochromatosis 蛋白质, HFE 和 haemojuvelin (HJV ) 一样的 ferroportin (FPN ) ,它正在表明分子。许多也这些基因参予铁集中于肝的肽 hepcidin 的规章的小径。然而,我们开始仍然仅仅正在理解在肝之间的复杂相互作用熨运输和铁动态平衡。这评论在铁运输和铁动态平衡的规定构画出我们铁新陈代谢和他们的角色的分子的当前的知识。 | Ross M Graham Anita CG Chua Carly E Herbison John K Olynyk Debbie Trinder | 2007 | World Journal of Gastroenterology2007，13，35： | 12 |
| 2 | Mapping landslide susceptibility at the Three Gorges Reservoir, China, using gradient boosting decision tree,random forest and information value models显示文摘This work was to generate landslide susceptibility maps for the Three Gorges Reservoir(TGR) area, China by using different machine learning models. Three advanced machine learning methods, namely, gradient boosting decision tree(GBDT), random forest(RF) and information value(InV) models, were used, and the performances were assessed and compared. In total, 202 landslides were mapped by using a series of field surveys, aerial photographs, and reviews of historical and bibliographical data. Nine causative factors were then considered in landslide susceptibility map generation by using the GBDT, RF and InV models. All of the maps of the causative factors were resampled to a resolution of 28.5 m. Of the 486289 pixels in the area,28526 pixels were landslide pixels, and 457763 pixels were non-landslide pixels. Finally, landslide susceptibility maps were generated by using the three machine learning models, and their performances were assessed through receiver operating characteristic(ROC) curves, the sensitivity, specificity,overall accuracy(OA), and kappa coefficient(KAPPA). The results showed that the GBDT, RF and In V models in overall produced reasonable accurate landslide susceptibility maps. Among these three methods, the GBDT method outperforms the other two machine learning methods, which can provide strong technical support for producing landslide susceptibility maps in TGR. | CHEN Tao ZHU Li NIU Rui-qing TRINDER C John PENG Ling LEI Tao | 2020 | Journal of Mountain Science2020，17，3： | 7 |
| 3 | Iron:An emerging factor in colorectal carcinogenesis显示文摘The carcinogenic potential of iron in colorectal cancer(CRC) is not fully understood.Iron is able to undergo reduction and oxidation,making it important in many physiological processes.This inherent redox property of iron,however,also renders it toxic when it is present in excess.Iron-mediated generation of reactive oxygen species via the Fenton reaction,if uncontrolled,may lead to cell damage as a result of lipid peroxidation and oxidative DNA and protein damage.This may promote carcinogenesis through increased genomic instability,chromosomal rearrangements as well as mutations of proto-oncogenes and tumour suppressor genes. Carcinogenesis is also affected by inflammation which is exacerbated by iron.Population studies indicate an association between high dietary iron intake and CRC risk.In this editorial,we examine the link betweeniron-induced oxidative stress and inflammation on the pathogenesis of CRC. | Anita CG Chua Borut Klopcic Ian C Lawrance John K Olynyk Debbie Trinder | 2010 | World Journal of Gastroenterology2010，16，6： | 3 |
| 4 | Modeling and representation issues in automated feature extraction from aerial and satellite images 显示文摘 | Arcot Sowmya John Trinder | 2000 | ISPRS Journal of Photogrammetry & Remote Sensing2000，55，： | 1 |
| 5 | Automatic Road Extraction from Aerial Images显示文摘 | John C. Trinder Yandong Wang | 1998 | Digital Signal Processing1998，，4： | 1 |
| 6 | Hepatic iron loading in mice increases cholesterol biosynthesis显示文摘 | Ross M. Graham Anita C. G. Chua Kim W. Carter Roheeth D. Delima Daniel Johnstone Carly E. Herbison Martin J. Firth Rebecca O’Leary Elizabeth A. Milward John K. Olynyk Debbie Trinder | 2010 | Hepatology2010，，2： | 1 |
| 7 | Using the Dempster–Shafer method for the fusion of LIDAR data and multi-spectral images for building detection显示文摘 | Franz Rottensteiner John Trinder Simon Clode Kurt Kubik | 2004 | Information Fusion2004，，4： | 1 |
| 8 | Using the Dempster–Shafer method for the fusion of LIDAR data and multi-spectral images for building detection显示文摘 | Franz Rottensteiner John Trinder Simon Clode Kurt Kubik | 2004 | Information Fusion2004，，： | 1 |
| 9 | Assessing environmental impacts of urban growth using remote sensing显示文摘This paper provides a study of the changes in land use in urban environments in two cities,Wuhan,China and western Sydney in Australia.Since mixed pixels are a characteristic of medium resolution images such as Landsat,when used for the classification of urban areas,due to changes in urban ground cover within a pixel,Multiple Endmember Spectral Mixture Analysis(MESMA)together with Super-Resolution Mapping(SRM)are employed to derive class fractions to generate classification maps at a higher spatial resolution using an Artificial Neural Network(ANN)predicted Wavelet method.Landsat images over the two cities for a 30-year period,are classified in terms of vegetation,buildings,soil and water.The classifications are then processed using Indifrag software to assess the levels of fragmentation caused by changes in the areas of buildings,vegetation,water and soil over the 30 years.The extents of fragmentation of vegetation,buildings,water and soil for the two cities are compared,while the percentages of vegetation are compared with recommended percentages of green space for urban areas for the benefit of health and well-being of inhabitants.Changes in Ecosystem Service Values(ESVs)resulting from the urbanization have been assessed for Wuhan and Sydney.The UN Sustainable Development Goals(SDG)for urban areas are being assessed by researchers to better understand how to achieve the sustainability of cities. | John Trinder Qingxiang Liu | 2020 | Geo-Spatial Information Science2020，23，1： | 1 |
| 10 | The Regulation of Cellular Iron Metabolism显示文摘 | Anita C. G. Chua Ross M. Graham Debbie Trinder John K. Olynyk | 2007 | Critical Reviews in Clinical Laboratory Sciences (-)2007，，5： | 1 |
| 11 | Clostridium difficile colitis causing toxic megacolon, severe sepsis and multiple organ dysfunction syndrome显示文摘 | Giles Dobson Caroline Hickey John Trinder | 2003 | Intensive Care Medicine2003，，6： | 1 |
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