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| 1 | 国际教育信息化2013地平线报告(高等教育版)显示文摘国际新媒体联盟(New Media Consortium,简称NMC)所发布的年度地平线报告已经成为全球范围内教育信息化发展的显示器与风向标。2012年10月,北京开放大学与美国新媒体联盟签署协议,授权北京开放大学作为其在中国发行其年度报告中文版的唯一官方机构。本期学报正式刊出的2013年度地平线报告显示,未来五年内影响高等教育的六大技术为:大规模开放网络课程、平板电脑、游戏和游戏化、学习分析技术、3D打印技术、可穿戴技术。这些新技术对于我们生活中的沟通交流、获取信息、社会交往、日常学习等方面正在产生重大而深远的影响。希望本报告能够有助于国内同行及时了解国际范围内教育信息化的发展趋势、新技术应用,为促进信息技术更有效地提高教学质量服务提供有益借鉴。新媒体联盟总裁莱瑞博士(Larry Johnson)专门写信祝贺2013年度地平线报告(中文版)刊出:'北京开放大学与新媒体联盟的合作已使成千上万的中国教育界同行有机会围绕教育技术及其在大学和中小学课堂应用问题参与全球对话。北京开放大学以其在教育技术、在线学习的实践探索及开展的国际合作等方面取得的业绩成为国际地平线项目有价值的合作者。你们为地平线专题研究做出了贡献,还承担了地平线报告(中文版)的翻译出版。借助你们的帮助,许多国外同行开始了解信息技术如何在中国这一人口大国的大学和中小学得到应用;同时,也使中国教育界了解世界各国同行正在开展的信息化实践探索。' | Johnson L. AdamsBecker S. Cummins M. Estrada V. Freeman A. Ludgate H. 张铁道 殷丙山 殷蕾 白晓晶 | 2013 | 北京广播电视大学学报2013，，2： | 50 |
| 2 | 减少急性冠状动脉综合征和卒中患者求医的延误——美国心脏协会心血管护理委员会和卒中委员会的科学声明显示文摘在寻求急性冠状动脉综合征和卒中症状的治疗方面,患者延误是限制提供这些疾病的确定性治疗的主要因素。尽管数十年来的研究和公众教育活动一直旨在缩短患者延误时间,但大多数患者仍然不能及时求医。在本科学声明中,我们总结了以下证据:(1)证明早期治疗的益处;(2)描述患者延误问题的程度;(3)确定与患者延误及时求医有关的因素;(4)揭示当前减少患者延误措施的不足。最后,提出临床实践和今后研究的建议。 | Debra K. Moser Laura P. Kimble Mark J. Alberts Angelo Alonzo Janet B. Croft Kathleen Dracup Kelly R. Evenson Alan S. Go Mary M. Hand Rashmi U. Kothari George A. Mensah Dexter L. Morris Arthur M. Pancioli Barbara Riegel Julie Johnson Zerwic 李宏建 曲东锋 | 2006 | 国际脑血管病杂志2006，14，10： | 39 |
| 3 | 2013地平线报告高等教育版(上)显示文摘美国新媒体联盟地平线报告系列是一项鉴别和描述未来五年内对全球教育产生巨大影响的新兴技术的综合性研究,旨在帮助教育领导者、政策制订者和教师们理解新兴技术,以及技术对教学和研究产生的潜在影响。自2004年以来地平线报告每年发布一次,均在全球范围内引起反响。2013地平线报告高等教育版于今年2月发布,该报告立足高等教育机构的现状,以全球化视角展望2013-2018未来五年间的技术发展和应用前景,包括大规模开放在线课程、平板电脑、游戏与游戏化、学习分析、3D打印、可穿戴技术等六项新兴技术,并概括了影响高等教育发展的六大趋势和高等教育面临的六大挑战。 | (美)NMC地平线项目 龚志武 吴迪 陈阳键 苏宏 王寒冰 Johnson L. Adams Becker S. Cummins M. Estrada V. Freeman A. Ludgate H. | 2013 | 广州广播电视大学学报2013，13，2： | 24 |
| 4 | 新媒体联盟2016地平线报告高等教育版显示文摘《2016地平线报告高等教育版》沿用以往讨论趋势和挑战的三元维度展开,即政策,领导力和实践,确定了18项未来五年极有可能影响高等教育变革的关键趋势、重大挑战和重要的技术进展。关键趋势中,长期趋势包括:推进创新文化、反思高校运作;中期趋势包括:学习空间的重构、转向深度学习;近期趋势包括:对测量学习持续关注、混合学习设计的广泛应用。就制约高等教育领域技术应用的挑战而言,正式与非正式学习的融合、数字素养的提升被认为是可解决的挑战,教育模式的竞争、个性化学习是艰巨的挑战,而平衡线上和线下生活、保持教育的切合性则是棘手的挑战。未来1-5年内,自带设备、学习分析和自适应学习、增强现实和虚拟现实、创客空间、情感计算、机器人技术将对高等教育产生重要影响。 | NMC地平线项目 苏宏 陈阳键 吴迪 龚志武 项荣健 Johnson L. Adams Becker S. Cummins M. Estrada V. Freeman A. Hall C. | 2016 | 广州广播电视大学学报2016，16，2： | 23 |
| 5 | 白蛋白刺激肾小管上皮细胞表达基质金属蛋白酶2和9显示文摘目的探讨白蛋白对近端肾小管上皮细胞表达基质金属蛋白酶2(MMP-2)和MMP-9的影响。方法大鼠近端肾小管细胞株NRK52E培养至70%或100%融合时,分别给予不同浓度(0.1~1.0g/L)去脂和非去脂牛血清白蛋白(dBSA和BSA)刺激,于24、48、72h收集培养液,用明胶酶谱和Western印迹方法检测培养液MMP-2和MMP-9活性和蛋白水平。结果与空白对照组比较,1.0g/LBSA刺激未完全融合NRK52E72h后,MMP-2和MMP-9活性分别上调276%、176%(P〈0.05)。与刺激24h比较,1.0g/LBSA刺激72h,在未完全融合NRK52E的MMP-2和MMP-9活性分别上调536%、148%;在完全融合NRK52E分别上调212%、184%(P〈0.05)。与完全融合NRK52E比较,1.0g/LBSA刺激未完全融合NRK52E 72h,MMP-2活性上调增加了274%,MMP-9活性上调减少了45.1%(P〈0.05)。dBSA刺激结果与BSA类似。结论白蛋白刺激呈剂量和时间依赖性上调近端肾小管细胞表达MMP-2和MMP-9。细胞完全融合可抑制MMP-2表达,促进MMP-9表达。 | 孙良忠 Ibrini Juma Parker Emma 陈述枚 Johnson Timothy S. El Nahas A. Meguid | 2007 | 中华肾脏病杂志2007，23，8： | 9 |
| 6 | Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology显示文摘 | Bernard Levin David A. Lieberman Beth McFarland Kimberly S. Andrews Durado Brooks John Bond Chiranjeev Dash Francis M. Giardiello Seth Glick David Johnson C. Daniel Johnson Theodore R. Levin Perry J. Pickhardt Douglas K. Rex Robert A. Smith Alan Thorson S | 2008 | Gastroenterology2008，，5： | 8 |
| 7 | 多囊卵巢综合征未治疗妇女分泌期子宫内膜中类固醇激素受体、辅助调节因子及子宫容受性相关分子研究显示文摘Objective: To evaluate gene and protein expression of steroid receptors, nuclear receptor coregulators, and uterine receptivity markers in midsecretory phase endometria from untreated women with polycystic ovary syndrome (PCOS).Design: Case-control study. Setting: Hospital research unit. Patient(s): Eight patients with PCOS and eight fertile women of similar age to those with PCOS. In-tervention(s): Endometrial samples were obtained from women with PCOS (PCOSE) and normal (NE)- women during the midsecretory phase of the menstrual cycle. Main Outcome Measure(s): Expression studies (immunohistoch-emistry, reverse transcription-polymerase chain reaction [RT- PCR] and Western blot). Result(s): Endometria from PCOS exhibit higher levels of messenger RNA (mRNA) and protein for estrogen receptor α and coactivators than NE. Epithelial cells had a greater expression of progesterone receptor in PCOSE, whereas, no differences were observed in gene and protein expression of the nuclear corepressor (NcoR)- and the antiadhesion molecule mucin type- 1 (MUC- 1) between PCOSE and NE. Immunodetection for the coactivator ARA70 was higher in PCOSE than in NE; in contrast, expression of β 3- integrin in epithelia was lower in PCOSE than in control endometria. Conclusion(s): The higher response to steroid hormones of endometria from untreated PCOS-women induces diminished expression of β 3 integrin, which partially explain implantation failure in PCOS patients. | Quezada S. Avellaira C. Johnson M.C. M. Vega 李跃萍 | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，0，8： | 7 |
| 8 | 左氧氟沙星、加替沙星及莫西沙星对肺结核患者的早期及延长早期杀菌活性显示文摘目的:评估左氧氟沙星、加替沙星及莫西沙星等新氟喹诺酮类药物对肺结核患者的早期杀菌活性及延长早期杀菌活性。设计:随机开放临床试验。40例成年新诊断的涂阳肺结核患者(每组10例)分别每日单一接受异烟肼300mg,或左氧氟沙星1000mg,或加替沙星400mg,或莫西沙星400mg的7天治疗。治疗前2天及单药治疗7天期间,每日收集痰液进行定量培养。计量单药治疗开始的头2天(0-2天)及治疗后5天(2-7天)的菌量下降情况,以评估各药的早期及延长早期杀菌活性。对实验室工作人员关于病人治疗分组信息采用单盲法。结果:异烟肼的早期杀菌活性为0.67log10cfu/毫升/天,高于莫西沙星(0.33log10cfu/毫升/天)及加替沙星(0.35log10cfu/毫升/天)。与每日1000mg左氧氟沙星的早期杀菌活性(0.45log10cfu/毫升/天)相比,无统计学差异(P=0.14)。3种氟喹诺酮类药物的早期杀菌活性(0-2天)与延长早期杀菌活性(2-7天)相似。总体说来,氟喹诺酮类药物的延长早期杀菌活性高于异烟肼。结论:莫西沙星、加替沙星及高剂量左氧氟沙星,虽然略低于异烟肼,但均有良好的早期杀菌活性,并具有较高的延长早期杀菌活性。有理由对这些药物敏感的结核病人进行进一步的治疗研究。 | J. L. Johnson D. J. Hadad W. H. Boom C. L. Daley C. A. Peloquin K. D. Eisenach D. D. Jankus S. M. Debanne E. D. Charlebois E. Maciel M. Palaci R. Dietzet 马玙(译) 屠德华(校) 张立兴(审) | 2006 | 国际结核病与肺部疾病杂志2006，1，2： | 5 |
| 9 | ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID Use: A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents显示文摘 | Deepak L. Bhatt James Scheiman Neena S. Abraham Elliott M. Antman Francis K.L. Chan Curt D. Furberg David A. Johnson Kenneth W. Mahaffey Eamonn M. Quigley Robert A. Harrington Eric R. Bates Charles R. Bridges Mark J. Eisenberg Victor A. Ferrari Mark A. Hl | 2008 | Circulation2008，，18： | 3 |
| 10 | Omega-3 supplementation and non-alcoholic fatty liver disease: A systematic review and meta-analysis显示文摘 | Helen M. Parker Nathan A. Johnson Catriona A. Burdon Jeffrey S. Cohn Helen T. O’Connor Jacob George | 2011 | Journal of Hepatology2011，，4： | 3 |
| 11 | Global patterns of hepatocellular carcinoma management from diagnosis to death: the BRIDGE Study显示文摘 | Joong‐Won Park Minshan Chen Massimo Colombo Lewis R. Roberts Myron Schwartz Pei‐Jer Chen Masatoshi Kudo Philip Johnson Samuel Wagner Lucinda S. Orsini Morris Sherman | 2015 | Liver Int2015，，9： | 3 |
| 12 | 输液方式行部分肠道营养治疗儿童活动性克罗恩病:一项随机对照试验显示文摘Background and aims: Total enteral nutrition (TEN) with a liquid formula can suppress gut inflammation and induce remission in active Crohn’s disease. The mechanism is obscure. Studies have suggested that long term nutritional supplementation with a liquid formula (partial enteral nutrition (PEN)) may also suppress inflammation and prevent relapse. The aim of this study was to compare PEN with conventional TEN in active Crohn’s disease. Patients and methods: Fifty children with a paediatric Crohn’s disease activity index (PCDAI) > 20 were randomly assigned to receive 50% (PEN) or 100% (TEN) of their energy requirement as elemental formula for six weeks. The PEN group was encouraged to eat an unrestricted dietwhile those receiving TEN were not allowed to eat. The primary outcome was achievement of remission (PCDAI < 10). Secondary analyses of changes in erythrocyte sedimentation rate (ESR), C reactive protein, albumin, and platelets were performed to look for evidence of anti-inflammatory effects. Results: Remission rate with PEN was lower than with TEN (15% v 42% ; p = 0.035). Although PCDAI fell in both groups (p = 0.001 for both), the reduction was greater with TEN (p = 0.005). Moreover, the fall in PCDAI with PEN was due to symptomatic and nutritional benefits. With both treatments there were significant improvements in relation to abdominal pain, “ sense of wellbeing', and nutritional status. However, only TEN led to a reduction in diarrhoea (p = 0.02), an increase in haemoglobin and albumin, and a fall in platelets and ESR. Conclusions: TEN suppresses inflammation in activeCrohn’s disease but PEN does not. This suggests that long term nutritional supplementation, although beneficial to some patients, is unlikely to suppress inflammation and so prevent disease relapse. | Johnson T. Macdonald S. Hill S.M. M.S. Murphy 程妍 | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，2，8： | 3 |
| 13 | Worsening renal function in heart failure: The need for a consensus definition显示文摘 | Noella J. Sheerin Phillip J. Newton Peter S. Macdonald Dominic Y.C. Leung David Sibbritt Stephen Timothy Spicer Kay Johnson Henry Krum Patricia M. Davidson | 2014 | International Journal of Cardiology2014，，： | 2 |
| 14 | Outcome After Colectomy for Clostridium Difficile Colitis显示文摘 | Walter E. Longo M.D. John E. Mazuski M.D. Katherine S. Virgo Ph.D. Paul Lee M.D. Anil N. Bahadursingh M.D. Frank E. Johnson M.D | 2004 | Diseases of the Colon & Rectum2004，，10： | 2 |
| 15 | Shapes and sizes of nanoscale Pb inclusions in Al显示文摘 | E. Johnson A. Johansen U. Dahmen S. Chen T. Fujii | 2001 | Materials Science & Engineering A2001，，： | 2 |
| 16 | Modeling Loss Aversion and Reference Dependence Effects on Brand Choice显示文摘 | Bruce G. S. Hardie Eric J. Johnson Peter S. Fader | 1993 | Marketing Science1993，，： | 2 |
| 17 | Plasma Tranexamic Acid Concentrations During Cardiopulmonary Bypass显示文摘 | Bridget K. Fiechtner Gregory A. Nuttall Michael E. Johnson Yue Dong Nuntiya Sujirattanawimol William C. Oliver Rajbir S. Sarpal Lance J. Oyen Mark H. Ereth | 2001 | Anesthesia and Analgesia2001，，5： | 2 |
| 18 | Stereotactic Body Radiotherapy for Primary Hepatocellular Carcinoma显示文摘 | David L. Andolino Cynthia S. Johnson Mary Maluccio Paul Kwo A. Joseph Tector Jennifer Zook Peter A.S. Johnstone Higinia R. Cardenes | 2011 | International Journal of Radiation Oncology, Biology, Physics2011，，4： | 2 |
| 19 | An anisotropic propagation technique for synthesizing hyperbranched polyvillic gold nanoparticles显示文摘近来,许多合成过程被学习了开发金 nanostructures 的不规则的 nano 形态学让生物医学的应用程序以便增加 nanoparticle theranostics 的功效,调节 plasmonic 吸收度系列,并且增加通过表面的 biomolecule 察觉的敏感提高的拉曼光谱学。这里,我们报导,一篇小说,非种子调停了能够与超过 50-90 分叉生产 hyperbranched 黄金 nano-polyvilli 的万用的单个壶合成方法在每结构以内从单个起源宣传的 nanowires。这种技术能够完成分叉能被改变孵化,温度,和氢离子集中的持续时间控制的分支繁殖的精确调节。 | Aaron S. Schwartz-Duval Santosh K. Misra Prabuddha Mukhejee Elyse Johnson Alvin S. Acerbo Dipanjan Pan | 2016 | Nano Research2016，9，10： | 2 |
| 20 | Multiphasic Enhancement Patterns of Small Renal Masses (≤4 cm) on Preoperative Computed Tomography: Utility for Distinguishing Subtypes of Renal Cell Carcinoma, Angiomyolipoma, and Oncocytoma显示文摘 | Phillip M. Pierorazio Elias S. Hyams Salina Tsai Zhaoyong Feng Bruce J. Trock Jeffrey K. Mullins Pamela T. Johnson Elliot K. Fishman Mohamad E. Allaf | 2013 | Urology2013，，6： | 2 |
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