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| 1 | Folate Biofortification of Potato by Tuber-Specific Expression of Four Folate Biosynthesis Genes显示文摘微量元素的不够的饮食的吸入,是隐藏饥饿知道,是破坏全球负担,影响 20 亿个人。folates (维生素 B9 ) 的缺乏,被知道在 C 1 新陈代谢起一个中央作用,每年在至少 1/4 百万个人引起出生缺点。在庄稼提高自然地发生的 folates 的水平的 Biofortification 种,证明是在战斗的一个有效、划算的工具叶酸的缺乏。以前,叶酸的生合成基因 GTPCHI 和模数转换器的介绍,证明是在米饭和西红柿的成功的 biofortification 策略,结果不够足够地在土豆 tubers 增加叶酸的层次。这里,我们提供概念的一个证明 HPPK/DHPS 或 FPGS 的那另外的介绍,在 mitochondrial 的下游的基因叶酸的生合成,启用 folates 的扩大到令人满意的层次(12 褶层) 并且在 tubers 的长期的存储之上保证叶酸的稳定性。在结论,这设计策略能在叶酸积累的土豆栽培变种的创造担任一个模型,在消费土豆的人口受不了容易地适用叶酸的缺乏。 | Jolien De Lepeleire Simon Strobbe Jana Verstraete Dieter Blancquaert Lars Ambach Richard G.F. Visser Christophe Stove Dominique Van Der Straeten | 2018 | Molecular Plant2018，11，1： | 12 |
| 2 | 二甲双胍长期治疗2型糖尿病患者以及维生素B12缺乏的危险性:随机安慰剂对照研究(摘要)显示文摘目的 研究接受胰岛素治疗的2型糖尿病患者中,二甲双胍所致维生素B12缺乏(〈150pmol/L)、低浓度维生素B12(150—220pmol/L)的发生率,以及叶酸和同型半胱氨酸的浓度。 | Jolien de Jager Adriaan Kooy Philippe Lehert Michiel G Wulffele Jan van der Kolk Daniel Bets Joop Verburg Ab J M Donker Coen D A Stehouwer 许翎岭(译) | 2010 | 英国医学杂志中文版2010，13，5： | 2 |
| 3 | Long-lasting symptoms and diagnostics in a patient with unrecognized right sided heart failure: Why listening to the heart is so important显示文摘M Ebstein is usually diagnosed in early childhood or ad-olescence. The young woman in our case complainted of fatigue and shortness of breath, on physical exami-nation she showed signs of heart failure with raised central venous pressure, palpable liver, an a cardiac murmer. Based on these findings she should have been referred to a cardiologist in an early stage after which transthoracic echocardiography resulted in the correct diagnosis. In this case the anomaly was missed for many years by different specialists and the patient was treated for liver disease, while she was suffering from liver congestion due to right-sided heart failure. | Liesbeth C de Vette Jasper J Brugts Jacky S McGhie Jolien W Roos-Hesselink | 2014 | World Journal of Cardiology2014，6，5： | 1 |
| 4 | Effects on startle responses in neonatally MSG-treated rats显示文摘 | YANG F C JOLIEN CONNOR ANISHA PATEL | 2000 | Physiology & Behavior2000，69，3： | 1 |
| 5 | Clinical Value of Real-Time Three-Dimensional Echocardiography for Right Ventricular Quantification in Congenital Heart Disease: Validation With Cardiac Magnetic Resonance Imaging显示文摘 | Heleen B. van der Zwaan Willem A. Helbing Jackie S. McGhie Marcel L. Geleijnse Saskia E. Luijnenburg Jolien W. Roos-Hesselink Folkert J. Meijboom | 2010 | Journal of the American Society of Echocardiography2010，，2： | 1 |
| 6 | Research:Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B - 12 deficiency : randomised placebo controlled trial 显示文摘 | Jolien de Jager Adriaan Kooy Philippe Lehert | 2010 | BMJ2010，340，： | 1 |
| 7 | Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab显示文摘 | Jolien Tol Jeroen R. Dijkstra Marjolein Klomp Steven Teerenstra Martin Dommerholt M. Elisa Vink-B?rger Patricia H. van Cleef J. Han van Krieken Cornelis J.A. Punt Iris D. Nagtegaal | 2010 | European Journal of Cancer2010，，11： | 1 |
| 8 | Outcome of Pregnancy in Women With Congenital Heart Disease显示文摘 | Willem Drenthen Petronella G. Pieper Jolien W. Roos-Hesselink Willem A. van Lottum Adriaan A. Voors Barbara J.M. Mulder Arie P.J. van Dijk Hubert W. Vliegen Sing C. Yap Philip Moons Tjark Ebels Dirk J. van Veldhuisen | 2007 | Journal of the American College of Cardiology2007，，24： | 1 |
| 9 | Outcome of Pregnancy in Women With Congenital Heart Disease显示文摘 | Willem Drenthen Petronella G. Pieper Jolien W. Roos-Hesselink Willem A. van Lottum Adriaan A. Voors Barbara J.M. Mulder Arie P.J. van Dijk Hubert W. Vliegen Sing C. Yap Philip Moons Tjark Ebels Dirk J. van Veldhuisen | 2007 | Journal of the American College of Cardiology2007，，24： | 1 |
| 10 | A qualitative participatory study to identify experiences of coronary heart disease patients to support the development of online self-management services显示文摘 | Sandra V Jolien J Pieter Jan S | 2013 | Int J Med Inform2013，82，12： | 1 |
| 11 | The role of the renin–angiotensin system in thoracic aortic aneurysms: Clinical implications显示文摘 | Els Moltzer Jeroen Essers Joep H.M. van Esch Jolien W. Roos-Hesselink A.H. Jan Danser | 2011 | Pharmacology and Therapeutics2011，，1： | 1 |
| 12 | Birth Prevalence of Congenital Heart Disease Worldwide显示文摘 | Denise van der Linde Elisabeth E.M. Konings Maarten A. Slager Maarten Witsenburg Willem A. Helbing Johanna J.M. Takkenberg Jolien W. Roos-Hesselink | 2011 | Journal of the American College of Cardiology2011，，21： | 1 |
| 13 | Test-Retest Variability of Volumetric Right Ventricular Measurements Using Real-Time Three-Dimensional Echocardiography显示文摘 | Heleen B. van der Zwaan Marcel L. Geleijnse Osama I.I. Soliman Jackie S. McGhie Ellen J.A. Wiegers-Groeneweg Willem A. Helbing Jolien W. Roos-Hesselink Folkert J. Meijboom | 2011 | Journal of the American Society of Echocardiography2011，，6： | 1 |
| 14 | Human pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus显示文摘 | Philip Roelandt Susan Obeid Jan Paeshuyse Jolien Vanhove Alfons Van Lommel Yaakov Nahmias Frederik Nevens Johan Neyts Catherine M Verfaillie | 2012 | Journal of Hepatology2012，，2： | 1 |
| 15 | A qualitative participatory study to identify experiences of coronary heart disease patients to support the development of online self-management services 显示文摘 | Sandra V Jolien J Pieter JS | 2013 | Int Med Inform NLM2013，82，12： | 1 |
| 16 | Monoclonal antibodies in the treatment of metastatic colorectal cancer: A review显示文摘 | Tol Jolien Punt CJ | 2010 | Clinical Thera- peutics2010，32，3： | 1 |
| 17 | Monoclonal antibodies in the treatment of metastatic colorectal cancer: A review显示文摘 | Jolien Tol Cornelis J.A. Punt | 2010 | Clinical Therapeutics2010，，3： | 1 |
| 18 | Is the god of diamonds alone? The role of institutions in artisanal mining in forest landscapes, Congo Basin显示文摘 | Jolien Schure Verina Ingram Julius Chupezi Tieguhong Cleto Ndikumagenge | 2011 | Resources Policy2011，，4： | 1 |
| 19 | Chemotherapy, Bevacizumab, and Cetuximab in Metastatic Colorectal Cancer显示文摘 | Jolien Tol Miriam Koopman Annernieke Cats | 2009 | New Engl J Med2009，360，6： | 1 |
| 20 | Comparison of Candesartan Versus Metoprolol for Treatment of Systemic Hypertension After Repaired Aortic Coarctation显示文摘 | Els Moltzer Francesco U.S. Mattace Raso Yusuf Karamermer Eric Boersma Gary D. Webb Maarten L. Simoons A.H. Jan Danser Anton H. van den Meiracker Jolien W. Roos-Hesselink | 2010 | The American Journal of Cardiology2010，，2： | 1 |
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