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您的检索式：作者名="Jonathan Tyler"
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| 1 | Histologic and Imaging Features of Mural Nodules in Mucinous Pancreatic Cysts显示文摘 | Ning Zhong Lizhi Zhang Naoki Takahashi Vladislav Shalmiyev Marcia Irene Canto Jonathan E. Clain John C. Deutsch John DeWitt Mohamad A. Eloubeidi Ferga C. Gleeson Michael J. Levy Shawn Mallery Massimo Raimondo Elizabeth Rajan Tyler Stevens Mark Topazian | 2012 | Clinical Gastroenterology and Hepatology2012，，2： | 2 |
| 2 | Consumer benefits and demand impacts of regular train timetables 显示文摘 | Mark Wardman Jeremy Shires William Lythgoe Jonathan Tyler | 2004 | International Journal of Transport Management2004，，2： | 1 |
| 3 | Development and assessment of a cutaneous tissue stretch device as a novel scar therapy显示文摘Aim:Scar prevention and reduction is an area of therapeutic opportunity and unmet medical need.With no current effective scar therapy,patients are often disappointed in their appearance post surgery and re-present to surgeons,only to be turned away.The purpose of this study was to develop and test a device that produces intermittent parallel stretch on new scars and to analyze its potential to reduce scarring.Methods:Mice were randomized into 5 scar stretch treatment groups:1 control,1 sham,and 3 stretch models(0.5×,1×,or 2×device strength)and treated for 10 days.Scars were scored using the Vancouver Scar Scale.Scar tissue samples were compared by histology and transforming growth factor beta 1(TGF-β1)expression between control and treatment groups.Results:Scar scores of 0.5×and 1×groups were significantly lower than the control group(P<0.05).Scar scores from the 1×treatment group were also significantly lower than the 0.5×group(P<0.05).Sham,control scar and 2×groups showed more collagen deposition and a thicker dermal scar than the 0.5×and 1×groups.Unstretched scars had fewer fibroblasts with more collagen deposition than the 0.5×and 2×groups.TGF-β1 levels were significantly lower in the 0.5×(342.1±9.2)and 1×(254.1±3.1)groups than in the control group(P<0.05).TGF-β1 levels in the 1×treatment group were also significantly lower than the 0.5×treatment group(P<0.05).Conclusion:Intermittent cutaneous tissue stretch parallel to scars during the proliferative phase of wound healing decreases fibrosis on a macroscopic,microscopic and biochemical level. | Jonathan Kanevsky Joshua Vorstenbosch Julian Diaz-Abele Tyler Safran Markus Prinz Youssef Tahiri Mirko Gilardino Satya Prakash | 2016 | Plastic and Aesthetic Research2016，3，1： | 0 |
| 4 | 产前和产后双酚A暴露和童年体质指数显示文摘[背景]双酚A(BPA)是一种广泛使用的内分泌干扰化学物,与啮齿类动物体重增加和脂肪沉积有关联。[目的]在CHAMACOS纵向队列的9岁儿童组(n=311)中,研究产前和产后尿BPA浓度与体质指数(BMI)、腰围、体脂肪率和肥胖间的关联。[方法]采集母亲怀孕期间现场收集的两次尿样以及5岁和9岁儿童的尿样,测量BPA浓度。[结果]产前尿BPA浓度与9岁女孩BMI降低有关联,但在男孩中无此关联。在女孩中,位于产前BPA浓度最高的三分位数与BMI z分值降低(β=-0.47,95%CI:-0.87~-0.07)和体脂肪率降低(β=-4.36,95%CI:-8.37~-0.34)有关联;与位于最低三分位数组的女孩相比,超重/肥胖的风险下降[比值比(OR)=0.37,95%CI:0.16~0.91]。这些发现在青春期前期的女孩中最强。5岁时的尿BPA浓度与5岁或9岁时任何人体测量学参数没有相关性,在9岁时的BPA浓度与男孩和女孩9岁时的BMI、腰围、脂肪量、超重/肥胖呈正相关。[结论]本研究的发现与其他横断面研究相一致,9岁时尿BPA浓度较高与9岁时肥胖增加相关联。然而,母亲怀孕期间BPA浓度增加与他们的女儿9岁时BMI、体内脂肪和超重/肥胖降低有关联。 | Kim G.Harley Raul Aguilar Schall Jonathan Chevrier Kristin Tyler Helen Aguirre Asa Bradman Nina T.Holland Robert H.Lustig Antonia M.Calafat Brenda Eskenazi | 2013 | 环境与职业医学2013，30，7： | 0 |
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