|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of penehyclidine in acute organophosphorus pesticide poisoning显示文摘BACKGROUND:Penehyclidine is a newly developed anticholinergic agent.We aimed to investigate the role of penehyclidine in acute organophosphorus pesticide poisoning(OP)patients.METHODS:We searched the Pubmed,Cochrane library,EMBASE,Chinese National Knowledge Infrastructure(CNKI),Chinese Biomedical literature(CBM)and Wanfang databases.Randomized controlled trials(RCTs)recruiting acute OP patients were identifi ed for meta-analysis.Main outcomes included cure rate,mortality rate,time to atropinization,time to 60%normal acetylcholinesterase(AchE)level,rate of intermediate syndrome(IMS)and rate of adverse drug reactions(ADR).RESULTS:Sixteen RCTs involving 1,334 patients were identifi ed.Compared with the atropineor penehyclidine-alone groups,atropine combined with penehyclidine significantly increased the cure rate(penehyclidine+atropine vs.atropine,0.97 vs.0.86,RR 1.13,95%CI[1.07–1.19];penehyclidine+atropine vs.penehyclidine,0.93 vs.0.80,RR 1.08,95%CI[1.01–1.15])and reduced the mortality rate(penehyclidine+atropine vs.atropine,0.015 vs.0.11,RR 0.17,95%CI[0.06–0.49];penehyclidine+atropine vs.penehyclidine,0.13 vs.0.08,RR 0.23,95%CI[0.04–1.28]).Atropine combined with penehyclidine in OP patients also helped reduce the time to atropinization and AchE recovery,the rate of IMS and the rate of ADR.Compared with a single dose of atropine,a single dose of penehyclidine also signifi cantly elevated the cure rate,reduced times to atropinization,AchE recovery,and rate of IMS.CONCLUSION:Atropine combined with penehyclidine benefi ts OP patients by enhancing the cure rate,mortality rate,time to atropinization,AchE recovery,IMS rate,total ADR and duration of hospitalization.Penehyclidine combined with atropine is likely a better initial therapy for OP patients than atropine alone. | Shi-yuan Yu Yan-xia Gao Joseph Walline Xin Lu Li-na Zhao Yuan-xu Huang Jiang Tao An-yong Yu Na Ta Ren-ju Xiao Yi Li | 2020 | World Journal of Emergency Medicine2020，11，1： | 18 |
| 2 | A wavelet-based approach for the identification of damping in non-linear oscillators 显示文摘 | Lardies Joseph Ta Minh-Nghi | 2005 | Journal of Mechanical Sciences2005，47，： | 1 |
| 3 | Neurobehavior of term neonates with neonatal Hyperbilirubinemia显示文摘 | Babu TA Bhat BV Joseph NM | 2013 | J Pediatr Neurosci2013，8，1： | 1 |
| 4 | A wavelet-based approach for the identification of damping in non-linear oscillators 显示文摘 | Lardies Joseph Ta Minh-Nghi | 2005 | Journal of Mechanical Sciences2005，47，： | 1 |
| 5 | An alternative Ca2+-dependent mechanism of neuroprotection by the metalloporphyrin class of superoxide dismutase mimetics显示文摘 | Josephs TA Eric B Natasa OR | | 0，，12： | 1 |
| 6 | A wavelet-based approach for the identification of damping in non-linear oscillators显示文摘 | Lardies Joseph Ta Minh-Nghi | 2005 | International Journal of Mechanical Science2005，47，： | 1 |
| 7 | Identification of weak nonlinearities on damping and stiffness by the continuous wavelet transform显示文摘 | Ta Minh-Nghi Lardies Joseph | 2006 | Journal of Sound and Vibration2006，293，： | 1 |
| 8 | Gene expression profi- ling signatures associated with RCC response to IL-2 therapy 显示文摘 | Libermann TA Bhasin M Joseph MG | 2008 | J lmmunother2008，31，9： | 1 |
| 9 | Hepatitis B prophylaxis in patients undergoing chemotherapy for lymphoma: a decision analysis model 显示文摘 | Saab S Dong MH Joseph TA | 2007 | Hepatology2007，46，4： | 1 |
| 10 | A wavelet-based approach for the i- dentification of damping in non-linear oscillators 显示文摘 | Lardies Joseph Ta Minh-Nghi | 2005 | Journal of Mechanical Sciences2005，47，： | 1 |
| 11 | Hepatitis B prophylaxis in patients undergoing chemotherapy for lymphoma: a decision analysis model 显示文摘 | Saab S Dong MH Joseph TA | 2007 | Hepatology2007，46，： | 1 |
| 12 | Hepatitis B prophylaxis in patients undergoing chemotherapy for lymphoma: a decision analysis model显示文摘 | Saab S Dong MH Joseph TA | 2007 | Hepatology2007，46，4： | 1 |
| 13 | A wavelet-based approach for the identification of damping in non-linear oscillators显示文摘 | Joseph L Ta M N | | 0，，08： | 1 |
| 14 | Neurobehavior of term neo- nates with neonatal hyperbilirubinemia 显示文摘 | Babu TA Bhat BV Joseph NM | 2013 | J Pediatr Neu- rosci2013，8，1： | 1 |
| 15 | Rupture of the subscapularis tendon after shoulder arthroplasty: diagnosis, treatment, and outcome显示文摘 | Miller BS Joseph TA Noonan TJ | 2005 | J Shoulder Elbow Surg2005，14，5： | 1 |
| 16 | Identification of weak nonlinearities on damping and stiffness by the continuous wavelet transform显示文摘 | Minh-Nghi Ta Joseph Lardiès | 2005 | Journal of Sound and Vibration2005，，1： | 1 |
| 17 | p-type Electrical Eonduction in ZnO Thin Films by Ga and N Codoping 显示文摘 | JOSEPH M TABA TA H KAWAI T | 1999 | J Appl Phys1999，38，11： | 1 |
| 18 | Identification of Weak Nonlinearities on Damping and Stiffness by the Continuous Wavelet Transform显示文摘 | Ta M N Joseph L | 2006 | Journal of Sound and Vibration2006，293，1： | 1 |
| 19 | Neurobehavior of term neonates with neonatal hyperbilirubinemia 显示文摘 | Babu TA Bhat BV Joseph NM | 2013 | J Pediatr Neurosci2013，8，1： | 1 |
| 20 | CoBRA: Containerized Bioinformatics Workflow for Reproducible Ch IP/ATAC-seq Analysis显示文摘Chromatin immunoprecipitation sequencing(Ch IP-seq)and the Assay for Transposase-Accessible Chromatin with high-throughput sequencing(ATAC-seq)have become essential technologies to effectively measure protein–DNA interactions and chromatin accessibility.However,there is a need for a scalable and reproducible pipeline that incorporates proper normalization between samples,correction of copy number variations,and integration of new downstream analysis tools.Here we present Containerized Bioinformatics workflow for Reproducible Ch IP/ATAC-seq Analysis(Co BRA),a modularized computational workflow which quantifies Ch IP-seq and ATAC-seq peak regions and performs unsupervised and supervised analyses.Co BRA provides a comprehensive state-of-the-art Ch IP-seq and ATAC-seq analysis pipeline that can be used by scientists with limited computational experience.This enables researchers to gain rapid insight into protein–DNA interactions and chromatin accessibility through sample clustering,differential peak calling,motif enrichment,comparison of sites to a reference database,and pathway analysis.Co BRA is publicly available online at https://bitbucket.org/cfce/cobra. | Xintao Qiu Avery S.Feit Ariel Feiglin Yingtian Xie Nikolas Kesten Len Taing Joseph Perkins Shengqing Gu Yihao Li Paloma Cejas Ningxuan Zhou Rinath Jeselsohn Myles Brown XShirley Liu Henry W.Long | 2021 | Genomics, Proteomics & Bioinformatics2021，19，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员