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| 1 | Phylogenetic relationships of Cyrtandromoea and Wightia revisited: A new tribe in Phrymaceae and a new family in Lamiales显示文摘The familial placements of Cyrtandromoea Zoll. and Wightia Wall., two small and enigmatic South‐East Asian genera, have long been controversial in Lamiales. Here we adopt a two‐step approach to resolve their phylogenetic relationships. We initially reconstructed a large‐scale phylogeny of Lamiales using six chloroplast markers (atpB, matK, ndhF, psbBTNH, rbcL, and rps4). The results showed that both Cyrtandromoea and Wightia emerged in the LMPO clade, including Lamiaceae, Mazaceae, Phrymaceae, Paulowniaceae, and Orobanchaceae. Based on the second set of six chloroplast markers (atpB, matK, ndhF, rbcL, rps16, and trnL‐F) and two nuclear ribosomal regions (external transcribed spacer and internal transcribed spacer) for the analyses focusing on the LMPO clade, our results revealed that Cyrtandromoea was consistently nested within Phrymaceae, whereas Wightia was supported as sister to Phrymaceae by the chloroplast DNA dataset or sister to Paulowniaceae by the nuclear ribosomal DNA dataset. Morphological and anatomical evidence fully supports the inclusion of Cyrtandromoea in Phrymaceae, and an updated tribal classification is done for Phrymaceae with five tribes, that is, Cyrtandromoeeae Bo Li, Bing Liu, Su Liu & Y. H. Tan, trib. nov., Diplaceae Bo Li, Bing Liu, Su Liu & Y. H. Tan, trib. nov., Leucocarpeae, Mimuleae, and Phrymeae. The conflicting phylogenetic position of Wightia indicated by different genome markers results in difficulty placing the genus in either Phrymaceae or Paulowniaceae. Considering the distinct morphological differences between Wightia and other families in the LMPO clade, we here propose a new family, Wightiaceae Bo Li, Bing Liu, Su Liu & Y. H. Tan, fam. nov., to accommodate it, which is the 26th family recognized in Lamiales. | Bing Liu Yun-Hong Tan Su Liu Richard GOlmstead Dao-Zhang Min Zhi-Duan Chen Nirmal Joshee Brajesh NVaidya Richard CKChung Bo Li | 2020 | Journal of Systematics and Evolution2020，58，1： | 8 |
| 2 | Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior显示文摘服的外皮为集成是必要的并且为大多数行为被要求的信息处理。当神经原从室的地区连续地移居联合进特定的外皮的层时,服的外皮的精致地精确的 laminar 组织在胚胎的开发期间产生。当时指南为设计神经原移植责骂的光线的神经胶质行为, pre-formed 脉管的网络为 GABAergic interneuron 移植提供支持和指导暗示。这研究提供新奇概念、机械学的卓见进 vascular-neuronal 相互作用的这个范例,揭示伽马氨基丁酸并且它经由胚胎的前脑 endothelial 房间的调停受体的发信号的新机制。与二个新 endothelial 房间的使用,特定的有条件的老鼠 GABA 小径当模特儿(Gabrb3 Tie2-Cre 和 Vgat 我们显示出的 Tie2-Cre ), 从 endothelial 房间的伽马氨基丁酸版本的那部分或完全的损失在 embryogenesis 期间导致脉管的缺点并且损害长途的移植并且外皮的 interneurons 放。使不安的 endothelial 的下游的效果导出房间的伽马氨基丁酸发信号是批评的,导致上次修改到外皮的电路和坚持的行为的赤字。而且,我们说明在支持他们血大脑障碍性质的迁居, angiogenesis 和获得的前脑 endothelial 房间发信号的伽马氨基丁酸的激活的新机制。我们的调查结果揭开并且阐明在从表明小径的古典 neuronal 伽马氨基丁酸是不同的并且在 neuropsychiatric 疾病的病原学和 pathophysiology 上打开新灯的 CNS 表明小径的新奇 endothelial 伽马氨基丁酸例如孤独性光谱混乱,癫痫,焦虑,消沉和精神分裂症。 | Suyan Li Peeyush Kumar Sampada Joshee Timo Kirschstein Sivan Subburaju Jahan S Khalili Jonas Kloepper Chuang Du Abdallah Elkhal Gabor Szabo Rakesh K Jain Rudiger Kohling Anju Vasudevan | 2018 | Cell Research2018，28，2： | 3 |
| 3 | Scutellaria extract and wogonin inhibit tumor-mediated induction of T (reg) ceils via inhibition of TGF-131 activi- ty 显示文摘 | Sagar Dandawate Linford Williams Nirmal Joshee | 2012 | Cancer Immunology Immunotherapy2012，61，5： | 1 |
| 4 | MRP2 and the handling of mercuric ions in rats exposed acutely to inorganic and organic species of mercury 显示文摘 | Bridges C C Joshee L Zalups R K | 2011 | Toxicol Appl Pharmacol2011，251，： | 1 |
| 5 | Scutellaria extract and wogonin inhibit tumor-mediated induction of T (reg) cells via inhibition of TGF-β1 activity 显示文摘 | Dandawate S Williams L Joshee N | 2012 | Cancer Immunol Immunother2012，61，5： | 1 |
| 6 | In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids 显示文摘 | Parajuli P Joshee N Rimando AM | 2009 | Planta medica2009，75，1： | 1 |
| 7 | Isolation and characterization of a water stress-specific genomic gene, pwsi 18, from rice 显示文摘 | Joshee N Kisaka H Kitagawa Y | 1998 | Plant and Cell Physiology1998，39，1： | 1 |
| 8 | Diversity and distribution of fungal foliar endophytes in New Zealand Podocarpaceae显示文摘 | Joshee S Paulus BC Park D | 2009 | Mycol Res2009，113，： | 1 |
| 9 | Transferrin-facilitated lipofection gene delivery strategy:characterization of the transfection complexes and intracellular trafficking显示文摘 | Joshee N Bastola DR Cheng PW | 2002 | Hum Gene Ther2002，13，： | 1 |
| 10 | Introduction of chilling resistance by water stress, and cDNA sequence - analysis and expression of water stress regulated gene in rice显示文摘 | Takahashi R Joshee N Kitajawa Y | 1994 | Plant Molecular Biology1994，26，1： | 1 |
| 11 | MRP2 and the han- dling of mercuric ions in rats exposed acutely to inorganic and organic species of mercury显示文摘 | Bridges C C Joshee L Zalups R K | 2011 | Toxicol Appl Pharm2011，251，1： | 1 |
| 12 | Aging and the dispo- sition and toxicity of mercury in rats 显示文摘 | Bridges C C Joshee L Zalups R K | 2014 | Exp Gerontol2014，53，2： | 1 |
| 13 | In vitro anti-tumor mechanisms of various Scutellaria extractsand constituent fla-vonoids 显示文摘 | Parajuli P Joshee N Rimando AM | 2009 | Planta Med2009，75，1： | 1 |
| 14 | Scutellaria extract and wogonin inhibit tumor-mediated induction of T(reg) cells via inhibition of TGF-betal activity 显示文摘 | Dandawate S Williams L Joshee N | 2011 | Cancer lmmunol lmmunother2011，61，5： | 1 |
| 15 | Scutellaria extract and wogonin inhibit tumor-mediated induction of T(reg)cells via inhi-bition of TGF-beta1 activity显示文摘 | Dandawate S Williams L Joshee N | | 0，，05： | 1 |
| 16 | In vitro antitu- mot mechanisms of various scutellaria extracts and constituent flavonoids 显示文摘 | Parajuli P Joshee N Rimando AM | 2009 | Planta Med2009，75，3： | 1 |
| 17 | Diversity and distribution of fungal foliar endophytes in New Zealand Podocar- paceae显示文摘 | JOSHEE S PAULUS B C PARK D | 2009 | Mycological Research2009，113，： | 1 |
| 18 | Novel Hg2 - in- duced nephropathy in rats and mice lacking Mrp2: evi- dence of axial heterogeneity in the handling of Hg2+ a- long the proximal tubule 显示文摘 | Zalups R K Joshee L Bridges C C | 2014 | Toxicol Sci2014，142，1： | 1 |
| 19 | In vitro antitumor mecha- nisms of various Scutellaria extracts and constituent flavonoids 显示文摘 | Parajuli P Joshee N Rimando AM | 2009 | Planta Med2009，75，1： | 1 |
| 20 | Scutellaria extract and wogonin inhibit tumor-mediated induction of T(reg) cells via inhibition of TGF-betal activity显示文摘 | Dandawate S Williams L Joshee N | 2012 | Cancer Immunol Im- munother2012，61，： | 1 |
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