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| 1 | Theoretical coupling longitudinal-transverse model and experimental verification of transverse vibration of rope for multi-rope friction hoisting system显示文摘 | Juan Wu Ziming Kou | 2016 | International Journal of Coal Science & Technology2016，3，1： | 4 |
| 2 | Gas injection membrane extraction for fast on-line analysis using GC detection显示文摘 | Kou D Juan A S Mitra S | 2001 | Anal Chem2001，73，22： | 1 |
| 3 | Four new labdane-type diterpenoid glycosides from Diplopterygium laevissimum显示文摘Four new labdane-type diterpenoid glycosides,laevissiosides A-D(1-4)were isolated from the 95%ethanol extract of Diplopterygium laevissimum(Christ)Nakai,along with two known analogues,18-b-D-glucopyranosyl ester-sclareol(5)and 18-hydroxy-sclareol(6).The structures of compounds 1-4 were elucidated by extensive 1D and 2D NMR spectroscopy as well as high-resolution MS analyses.All isolated compounds were evaluated for their cytotoxic effects. | Ming-Ming LI Kou WANG Juan HE Li-Yan PENG Xuan-Qin CHEN Xiao CHENG Qin-Shi ZHAO | 2013 | Natural Products and Bioprospecting2013，3，2： | 1 |
| 4 | Catalytic hydrolysis of carboxylic acid esters by Cu(Ⅱ) and Zn(Ⅱ) complexes containing a tetracoordinate macrocyclic Schiff base ligand in Brij35 micellar solution显示文摘 | Kou Xingrning Cheng Siqing Duan Juan | 2004 | Journal of Molecular Catalysis A : Chemical2004，210，1： | 1 |
| 5 | Genetic lineage tracing identifies cardiac mesenchymal-to-adipose transition in an arrhythmogenic cardiomyopathy model显示文摘Arrhythmogenic cardiomyopathy(ACM)is one of the most common inherited cardiomyopathies,characterized by progressive fibrofatty replacement in the myocardium.However,the cellular origin of cardiac adipocytes in ACM remains largely unknown.Unraveling the cellular source of cardiac adipocytes in ACM would elucidate the underlying pathological process and provide a potential target for therapy.Herein,we generated an ACM mouse model by inactivating desmosomal gene desmoplakin in cardiomyocytes;and examined the adipogenic fates of several cell types in the disease model.The results showed that SOX9^(+),PDGFRa^(+),and PDGFRb^(+)mesenchymal cells,but not cardiomyocytes or smooth muscle cells,contribute to the intramyocardial adipocytes in the ACM model.Mechanistically,Bmp4 was highly expressed in the ACM mouse heart and functionally promoted cardiac mesenchymal-to-adipose transition in vitro. | Xinyan Huang Lei Yan Jufeng Meng Nanbo Liu Shuoji Zhu Zhen Jiang Shan Kou Teng Feng Chao-Po Lin Bin Zhou Juan Tang Ping Zhu Hui Zhang | 2023 | Science China(Life Sciences)2023，66，1： | 1 |
| 6 | Ternary Self-Assembly of OrderedMetal Oxide Graphene Nanocomposites for Electrochemical Energy Storage显示文摘 | Donghai Wang Rong Kou Daiwon Choi Zhenguo Yang Zimin Nie Juan Li | 2010 | ACS NANO2010，3，： | 1 |
| 7 | Based on risk source pipe leakage emergency device and sealing method research 显示文摘 | YAN Hong-wei KOU Zi-ming WU Juan | 2011 | Advanced Materials Research2011，，287290： | 1 |
| 8 | Catalytic hydrolysis of carboxylic acid esters by Cu (Ⅱ) and Zn (Ⅱ) complexes containing a tetracoordinate macrocyclic Schiff base ligand in Brij35 micellar solution 显示文摘 | Cheng Siqing Du Juan | 2004 | Jounal of Molecular Catalysis A:Chemical2004，210，12： | 1 |
| 9 | Effects of Shengmai Yin(生脉饮)on pulmonary and cardiac function in coronavirus disease 2019 convalescent patients with cardiopulmonary symptoms:a randomized,double blind,multicenter control trial显示文摘OBJECTIVE:To evaluate the efficacy and safety of Shengmai Yin(生脉饮,SMY)on visual analogue scale(VAS)for cardiopulmonary symptoms in coronavirus disease 2019(COVID-19)convalescent patients.METHODS:In this randomized,double blind and multicenter controlled trial,a total of 200 COVID-19 convalescent patients who with cardiopulmonary symptoms were enrolled from three medical centers in Hubei,China.These patients were randomized divided into trial group and the control group,100 patients in each one,SMY and its placebo were applied to respectively,for two weeks.VAS of clinical symptoms included shortness of breath,hidrosis,chest distress,palpitation,and dry cough was performed at 0,1,2 weeks.Decrease in VAS of 30%or more was defined as effective,and a reduction in VAS of 0 was defined as curative.RESULTS:A total of 192 completed the study.The VAS of TCM symptoms showed there was no difference in baseline between the two groups.The VAS in both groups was down-regulated,and there was no significant difference in VAS and cure rates at the first and second week between the two groups.There was no significant difference in breath,hidrosis,palpitation,and dry cough between the two groups but SMY treatment for two weeks has remarkable therapeutic effects in chest distress than placebo.CONCLUSIONS:SMY could effectively ameliorate the symptoms of chest distress,and improve the quality of life of the COVID-19 convalescent patients. | AN Xuedong MAO Lina XIA Ping SU Wen WANG Beibei KOU Leiya ZHANG Zequan QI Meng HU Song CHEN Jing LI Xiujuan LIU Jinwei ZHOU Juan QIAO Jie LUO Dan LUO Guangwei YAN Youqin YANG Guiping DONG Dandan ZHOU Wei TAO Junxiu JIN De TONG Xiaolin WEI Li | 2023 | Journal of Traditional Chinese Medicine2023，43，1： | 1 |
| 10 | A brain structural connectivity biomarker for autism spectrum disorder diagnosis in early childhood显示文摘Background:Autism spectrum disorder(ASD)is associated with altered brain development,but it is unclear which specific structural changes may serve as potential diagnostic markers,particularly in young children at the age when symptoms become fully estab-lished.Furthermore,such brain markers need to meet the requirements of precision medicine and be accurate in aiding diagnosis at an individual rather than only a group level.Objective:This study aimed to identify and model brain-wide differences in structural connectivity using diffusion tensor imaging(DTI)in young ASD and typically developing(TD)children.Methods:A discovery cohort including 93 ASD and 26 TD children and two independent validation cohorts including 12 ASD and 9 TD children from three different cities in China were included.Brain-wide(294 regions)structural connectivity was measured using DTI(fractional anisotropy,FA)together with symptom severity and cognitive development.A connection matrix was constructed for each child for comparisons between ASD and TD groups.Pattern classification was performed on the discovery dataset and the resulting model was tested on the two independent validation datasets.Results:Thirty-three structural connections showed increased FA in ASD compared to TD children and associated with both autistic symptom severity and impaired general cognitive development.The majority(29/33)involved the frontal lobe and comprised five different networks with functional relevance to default mode,motor control,social recognition,language and reward.Overall,clas-sification achieved very high accuracy of 96.77%in the discovery dataset,and 91.67%and 88.89%in the two independent validation datasets.Conclusions:Identified structural connectivity differences primarily involving the frontal cortex can very accurately distinguish novel individual ASD from TD children and may therefore represent a robust early brain biomarker which can address the requirements of precision medicine. | Xi Jiang Xiao-Jing Shou Zhongbo Zhao Yuzhong Chen Fan-Chao Meng Jiao Le Tian-Jia Song Xin-Jie Xu Weitong Guo Xiaoyan Ke Xiao-E Cai Weihua Zhao Juan Kou Ran Huo Ying Liu Hui-Shu Yuan Yan Xing Ji-Sheng Han Song-Ping Han Yun Li Hua Lai Lan Zhang Mei-Xiang Jia Jing Liu Xuan Liu Keith M.Kendrick Rong Zhang | 2023 | Psychoradiology2023，3，1： | 0 |
| 11 | Exploring Sulfur Chemistry in TMC-1 with NSRT显示文摘There have been several studies on sulfur depletion in dense cores like TMC-1(Taurus Molecular Cloud 1),employing updated reaction networks for sulfur species to explain the missing sulfur in the gas within dense clouds.Most of these studies used a C/O ratio of 0.7 or lower.We present NSRT(NanShan 26m Radio Telescope)observations of TMC-1 alongside results from time-dependent chemical simulations using an updated chemical network.Our findings highlight the impact of the C/O ratio on the gas-phase evolution of C2S and C3S.The simulation results show that the C/O ratio is an important parameter,playing a fundamental role in determining the gas-phase abundances of sulfur species in dense cores. | Wasim Iqbal Xiaohu Li Juan Tuo Ryszard Szczerba Yanan Feng Zhenzhen Miao Jiangchao Yang Jixing Ge Gleb Fedoseev Donghui Quan Qiang Chang Chuan-Lu Yang Tao Yang Gao-Lei Hou Yong Zhang Xuan Fang Xia Zhang Fangfang Li Rong Ma Xiaomin Song Zhiping Kou Yuxuan Sun | 2024 | Chinese Physics Letters2024，41，2： | 0 |
| 12 | Development of plant cytosine base editors with the Cas12a system显示文摘Base editors of the Cas9 system have been widely used for precise nucleotide substitution in crops. In this study, Cas12a was applied to construct plant cytosine base editors(CBEs). The main elements of Cas12aCBEs were engineered and their efficiency was evaluated in stably transformed rice cells. An optimized ttCas12a-hyA3Bctd editor, consisting of a LbCas12a variant carrying catalytic inactive D832A and temperature-tolerance D156R double mutations, a truncated human APOBEC3B deaminase, a human RAD51 single-stranded DNA-binding domain, and double copies of UGI, outperformed other Cas12aCBEs in base editing efficiency. In T0transgenic rice plants, ttCas12a-hyA3Bctd edited an average of42.01% and a maximum of 68.75% of lines at six genomic targets. A-to-G conversions were generated in rice by an adenine base editor with a similar architecture to the optimized CBE. Our results provide preliminary evidence for the feasibility of robust and efficient plant Cas12a base editing systems, which could be useful for precise crop breeding. | Huanhuan Wang Jing Liang Like Chen Bufang Deng Dongfang Gu Xiaoshuang Liu Shan Jin Rongfang Xu Ruiying Qin Yitong Zhu Liangxia Zhao Dourong Kou Yanjun Chen Yingli Jiang Juan Li Pengcheng Wei | 2023 | The Crop Journal2023，11，5： | 0 |
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