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5篇 您的检索式:作者名="Junho Oh"
    题名 作者 年代 出处 被引量
1The originality of acupuncture in chosun dynasty found in introduction to medicine显示文摘Junho Oh Namil Kim Wungseok Cha 2009Korean Journal of Oriental Medicine2009,15,1:1
2The Originality of Acupuncture in Chosun Dynasty found in Introduction to Medicine显示文摘Junho Oh Namil Kim Wungseok Cha 2009KOREAN JOURNAL OF ORIENTAL MEDICINE2009,15,1:1
3Sliding mode control with uncertainty adaptation for uncertain input-delay systems显示文摘Roh Younghoon Oh Junho 2000Int J Control2000,73,13:1
4Cytochrome b5 Reductase 1 Triggers Serial Reactions that Lead to Iron Uptake in Plants显示文摘根围使发酸为铁(Fe ) 是必要的举起进植物根。在根围使发酸的血浆膜(下午) H +-ATPases 戏钥匙角色。然而,下午 H +-ATPase 活动怎么被调整在 Fe 缺乏的条件下面提高根 Fe 举起,充分没被理解。这里,我们现在的证据那细胞色素 b5 reductase (CBR1 ) 1 增加不饱和的丰满的酸的层次,它 stimulatePM H +-ATPase 活动并且这样 leadto 根围使发酸。不饱和的丰满的酸(18:2 和 18:3 ) 高级的有的 CBR1-overexpressing (CBR1 公牛) Arabidopsis thaliana 植物,更高级的下午 H +-ATPase 活动,和比野类型的植物的更低的根围 pH。由对比, cbr1loss-of-function 异种植物显示出不饱和的丰满的酸和更低的下午 H +-ATPase 活动的底层但是更高的根围 pH。在 cbr1 的减少的下午 H +-ATPase 活动能是由不饱和的丰满的酸的增加的恢复 invitro。CBR1,丰满的酸 desaturase2 (FAD2 ) ,和丰满的酸 desaturase3 (FAD3 ) 的抄本层次在 Fe 缺乏的条件下面被增加。我们建议 CBR1 在增加不饱和的丰满的酸的层次有一个关键角色,它 activatethe 下午 H +-ATPase 并且这样 reducerhizosphere pH。这反应串联最终支持根 Fe 举起。Young Jun Oh Hanul Kim Sung Hee Seo Bae Geun Hwang Yoon Seok Chang Junho Lee Dong Wook Lee Eun Ju Sohn Sang Joon Lee Youngsook Lee Inhwan Hwang 2016Molecular Plant2016,9,4:1
5DNA-based artificial dendritic cells for in situ cytotoxic T cell stimulation and immunotherapy显示文摘In immunotherapy,ex vivo stimulation of T cells requires significant resources and effort.Here,we report artificial dendritic cell-mimicking DNA microflowers(DM)for programming T cell stimulation in situ.To mimic dendritic cells,DNA-based artificial dendritic microflowers were constructed,surface-coated with polydopamine,and further modified with anti-CD3 and anti-CD28 antibodies to yield antibody-modified DM(DM-A).The porous structure of DM-A allowed entrapment of the T cell-stimulating cytokine,ineterleukin-2,yielding interleukin-2-loaded DM-A(DM-AI).For comparison,polystyrene microparticles coated with polydopamine and modified with anti-CD3 and anti-CD28 antibodies(PS-A)were used.Compared to PS-A,DM-AI showed significantly greater contact with T cell surfaces.DM-AI provided the highest ex vivo expansion of cytotoxic T cells.Local injection of DM-AI to tumor tissues induced the recruitment of T cells and expansion of cytotoxic T cells in tumor microenvironments.Unlike the other groups,model animals injected with DM-AI did not exhibit growth of primary tumors.Treatment of mice with DM-AI also protected against growth of a rechallenged distant tumor,and thus prevented tumor recurrence in this model.DM-AI has great potential for programmed stimulation of CD8+T cells.This concept could be broadly extended for the programming of specific T cell stimulation profiles.Quoc-Viet Le Jaiwoo Lee Junho Byun Gayong Shim Yu-Kyoung Oh 2022Bioactive Materials2022,7,9:0
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