|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | MiRNA-206 inhibits hepatocellular carcinoma cell proliferation and migration but promotes apoptosis by modulating cMET expression显示文摘A close relationship between cancer progression and microRNAs(miRNAs)regulation has been demonstrated.Abnormal microRNA-206(miR-206)expression has been shown to be related to the development of malignancies.However,the role of miR-206 in hepatocellular carcinoma(HCC)remains unclear.Here,we evaluated the function of miR-206 in HCC.Results showed that miR-206 expression was decreased in 27 human HCC tissues compared with that of adjacent normal tissues.Conversely,cMET was up-regulated in human HCC cancer tissues,and cMET levels were shown to be negatively correlated with miR-206 expression.Abnormally increased miR-206 expression in three HCC cell lines(SMMC-7721,HepG2,and Huh7)attenuated cell viability,migration,and invasion.Increased apoptosis was also observed in these miR-206 expressing cells.Furthermore,we identified that miR-206 targets the 3′-UTR of the cMET gene for silencing,and restoration of cMET expression reversed the inhibitory effect of miR-206 on HCC.Tumor cells expressing miR-206 also showed delayed growth in the in vivo experiments compared with the controls.Altogether,our findings provide new insights into the molecular mechanisms of HCC oncogenesis. | Yuanxi Wang Qinwen Tai Jinhui Zhang Junsheng Kang Feng Gao Feng Zhong Liquan Cai Fa Fang Yi Gao | 2019 | Acta Biochimica et Biophysica Sinica2019,51,3: | 7 |
| 2 | An ensemble local means decomposition method and its application to local rub-impact fault diagnosis of the rotor systems显示文摘 | YANG Yu CHENG Junsheng ZHANG Kang | 2011 | Measurement2011,,: | 1 |
| 3 | An Order TraRcking Technique for the Gear Fault Diagnosis Using Local Mean Decomposition Method显示文摘 | CHENG Junsheng ZHANG Kang YANG Yu | 2012 | Mechanism and Machine Theory2012,55,: | 1 |
| 4 | Cobalt tungsten phosphide with tunable W-doping as highly efficient electrocatalysts for hydrogen evolution reaction显示文摘It has been of interest in seeking electrocatalysts that could exercise equally high-efficient and durable hydrogen evolution upon nonselective electrolytes in both acidic and alkaline environments. Herein, we report a facile strategy to fabricate cobalt tungsten phosphides (CoxW2−xP2/C) hollow polyhedrons with tunable composition based on metal-organic frameworks (MOFs) template method. By the deliberate control of W doping, the synthesized catalyst with the composition of Co0.9W1.1P2/C is found to be able to achieve a current density of 10 mA·cm^(−2) at overpotentials of 35 and 54 mV in acidic and alkaline media, respectively. This combined electrochemical property stands atop the state-of-the-art electrocatalyst counterparts. To unveil the peculiar behavior of the structure, density functional theory (DFT) calculation was implemented and reveals that the surface W-doping facilitates the optimization of hydrogen absorption free energy (ΔGH*) as well as the thermodynamic and kinetics barriers for water dissociation, which is coupled with the hollow structure of Co-W phosphides, leading to the prominent HER catalytic performance. | Bowei Zhang Chaojiang Li Jun Hu Dongdong Peng Kang Huang Junsheng Wu Zhong Chen Yizhong Huang | 2021 | Nano Research2021,14,11: | 1 |
| 5 | An Ensem-ble Local Means Decomposition Method and ItsApplication to Local Rub-impact Fault Diagnosis ofthe Rotor Systems 显示文摘 | Yang Yu Cheng Junsheng Zhang Kang | 2012 | Measurement2012,45,3: | 1 |
| 6 | An En- semble Local Means Decomposition Method and Its Application to Local Rub-impact Fault Diagnosis of the Rotor Systems显示文摘 | Yang Yu Cheng Junsheng Zhang Kang | 2012 | Measurement2012,45,3: | 1 |
| 7 | An ensemble local means decomposition method and its application to local rub-impact fault diagnosis of the rotorsystems显示文摘 | YANG Yu CHENG Junsheng ZHANG Kang | 2012 | Measurement2012,45,3: | 1 |
| 8 | Studies of catalytic partial oxidation of methane to synthesis gas显示文摘 | Yu JunSheng Kang XingWu Yu ZuoLong | 1997 | Journal of Natural Gas Chemstry1997,6,1: | 1 |
| 9 | Electrochemical behaviors of hierarchical copper nano- dendrites in alkaline media显示文摘在这研究,层次铜 nano 树突(CuNDs ) 经由电极淀积方法被制作。在 0.1 M NaOH 水的答案的同样获得的层次 CuNDs 的电气化学的行为随后被学习。CuNDs 当使遭到了到周期的 voltammetry (CV ) 时,经历一个非平衡氧化过程大小。在 CV 的第一氧化山峰 O1 被归因于取向附生的 Cu 2 在层次 CuNDs 的表面上的 O 层。然而,在 CV 的第二氧化山峰 O 2 越过一个宽潜在的范围显得不平常地宽广。在这个区域,反应过程以 Cu 的成核和生长开始(哦)2 nanoneedles,由 Cu 2 O。在潜力的增加之后, Cu 2 O 逐渐地被转变到 CuO 和 Cu (哦) 与 Cu 的高生产率形成双层的结构的 2,( 哦)2 nanoneedles。 | Bowei Zhang Guang Yang Chaojiang Li Kang Huang Junsheng Wu Shiji Hao Yizhong Huang | 2018 | Nano Research2018,11,8: | 0 |
| 10 | Corrosion engineering on AlCoCrFeNi high-entropy alloys toward highly efficient electrocatalysts for the oxygen evolution of alkaline seawater显示文摘Seawater splitting is a prospective approach to yield renewable and sustainable hydrogen energy.Complex preparation processes and poor repeatability are currently considered to be an insuperable impediment to the promotion of the large-scale production and application of electrocatalysts.Avoiding the use of intricate instruments,corrosion engineering is an intriguing strategy to reduce the cost and presents considerable potential for electrodes with catalytic performance.An anode comprising quinary AlCoCrFeNi layered double hydroxides uniformly decorated on an AlCoCrFeNi high-entropy alloy is proposed in this paper via a one-step corrosion engineering method,which directly serves as a remarkably active catalyst for boosting the oxygen evolution reaction(OER)in alkaline seawater.Notably,the best-performing catalyst exhibited oxygen evolution reaction activity with overpotential values of 272.3 and 332 mV to achieve the current densities of 10 and100 mA·cm^(-2),respectively.The failure mechanism of the obtained catalyst was identified for advancing the development of multicomponent catalysts. | Zhibin Chen Kang Huang Bowei Zhang Jiuyang Xia Junsheng Wu Zequn Zhang Yizhong Huang | 2023 | International Journal of Minerals,Metallurgy and Materials2023,30,10: | 0 |