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您的检索式：作者名="K.M.Venkat"
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| 1 | 糖尿病转化研究的概念和发展概况显示文摘'2012年度的北大糖尿病论坛(PUDF)'于5月5~6日在北京九华山会议中心隆重举办。本届论坛以'糖尿病转化医学'为主题,会议邀请到美国CDC糖尿病流行病学与统计学分支负责人、美国埃默里大学的K.M.Venkat Narayan教授作'糖尿病转化医学研究———理念和发展'的主旨报告。Narayan教授是转化医学概念的提出者之一,在转化医学领域有很深造诣。Narayan在报告中介绍了转化医学的概念和发展概况,内容精辟。本刊征得Narayan教授的同意,由北京大学人民医院内分泌科罗樱樱医师翻译整理,现发表如下,以飨读者。 | K.M.Venkat Narayan 罗樱樱 | 2012 | 中国糖尿病杂志2012，20，6： | 3 |
| 2 | Lifestyle Interventions and the Prevention and Treatment of Type 2 Diabetes显示文摘 | Mary Beth Weber Jennifer G.Twombly K.M.Venkat Narayan | | 0，，： | 1 |
| 3 | Plasma lipoproteins and incidence of non-insulin-dependent diabetes mellitus in Pima Indians: protective effect of HDL cholesterol in women显示文摘 | Anne Fagot-Campagna K.M.Venkat Narayan Robert L Hanson Giuseppina Imperatore Barbara V Howard Robert G Nelson David J Pettitt William C Knowler | 1997 | Atherosclerosis1997，，1： | 1 |
| 4 | Health consequences of early-onset compared with late-onset type 2 diabetes mellitus显示文摘Background:Although cumulating evidence has suggested that early-onset type 2 diabetes mellitus(T2DM)conferred on patients a broader tendency for complications beyond vascular ones,a comprehensive analysis of patterns of complications across all relevant systems is currently lacking.Method:We prospectively studied 1777 early-onset(age at diagnosis≤45 years)and 35889 late-onset(>45 years)T2DM patients with matched unexposed individuals from the UK Biobank.Diabetes-specific and-related complications were examined using phenomewide association analysis,with patterns identified by comorbidity network analysis.We also evaluated the effect of lifestyle modifications and glycemic control on complication development.Results:The median follow-up times for early-onset and late-onset T2DM patients were 17.83 and 9.39 years,respectively.Compared to late-onset T2DM patients,patients with early-onset T2DM faced a significantly higher relative risk of developing subsequent complications that primarily affected sense organs[hazard ratio(HR)3.46 vs.1.72],the endocrine/metabolic system(HR 3.08 vs.2.01),and the neurological system(HR 2.70 vs.1.81).Despite large similarities in comorbidity patterns,a more complex and well-connected network was observed for early-onset T2DM.Furthermore,while patients with early-onset T2DM got fewer benefits(12.67%reduction in pooled HR for all studied complications)through fair glycemic control(median HbA1c≤53 mmol/mol)compared to late-onset T2DM patients(18.01%reduction),they seemed to benefit more from favorable lifestyles,including weight control,healthy diet,and adequate physical activity.Conclusions:Our analyses reveal that early-onset T2DM is an aggressive disease resulting in more complex complication networks than late-onset T2DM.Aggressive glucose-lowering intervention,complemented by lifestyle modifications,are feasible strategies for controlling early-onset T2DM-related complications. | Can Hou Huazhen Yang Yuanyuan Qu Wenwen Chen Yu Zeng Yao Hu K.M.Venkat Narayan Huan Song Dong Li | 2022 | Precision Clinical Medicine2022，5，2： | 1 |
| 5 | Microalbuminuria in the US population: Third National Health and Nutrition Examination Survey显示文摘 | Camille A. Jones Mildred E. Francis Mark S. Eberhardt Blanche Chavers Josef Coresh Michael Engelgau John W. Kusek Danita Byrd-Holt K.M.Venkat Narayan William H. Herman Camara P. Jones Marcel Salive Lawrence Y. Agodoa | 2002 | American Journal of Kidney Diseases2002，，3： | 1 |
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