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| 1 | Factor analysis identifies subgroups of constipation显示文摘AIM:To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction.METHODS:One hundred and ninety-one patients presenting to a Gastroenterology clinic with constipation and 32 constipated patients responding to a newspaper advertisement completed a 53-item,wide-ranging selfreport questionnaire.One hundred of these patients had colonic transit measured scintigraphically.Factor analysis determined whether constipation-related symptoms grouped into distinct aspects of symptomatology.Cluster analysis was used to determine whether indi-vidual patients naturally group into distinct subtypes.RESULTS:Cluster analysis yielded a 4 cluster solution with the presence or absence of pain and laxative unresponsiveness providing the main descriptors.Amongst all clusters there was a considerable proportion of patients with demonstrable delayed colon transit,irritable bowel syndrome positive criteria and regular stool frequency.The majority of patients with these characteristics also reported regular laxative use.CONCLUSION:Factor analysis identified four constipation subgroups,based on severity and laxative unresponsiveness,in a constipated population.However,clear stratification into clinically identifiable groups remains imprecise. | Philip G Dinning Mike Jones Linda Hunt Sergio E Fuentealba Jamshid Kalanter Denis W King David Z Lubowski Nicholas J Talley Ian J Cook | 2011 | World Journal of Gastroenterology2011，17，11： | 3 |
| 2 | Prednisone,azathioprine,and N-acetylcysteine for pulmonary fibrosis显示文摘 | Raghu G Anstrom K J King TE Jr | | 0，，21： | 2 |
| 3 | Pulmonary alveolar microlithiasis: an interesting case report with systematic review of Indian literature显示文摘肺的牙槽的 microlithiasis 是 microliths 的 intra 牙槽的存在描绘的稀罕疾病。这研究报导肺的牙槽的 microlithiasis 的一个有趣的案例并且提供从印度报导的案例的系统的评论。与咳嗽,喘息,胸疼痛,和阵发性的喘息的历史介绍五个月的 23 岁的女性。肺的功能测试表明了一个妨碍的模式,并且胸 X 射线显示出主要包含两个肺的中间、更低的地区的好 micronodular 暗。Transbronchial 肺活体检视揭示了诊断。她对吸入的类固醇治疗作出回应很好。文学的系统的评论被执行并且鉴别肺的牙槽的 microlithiasis 的 73 个案例从印度报导了。病人的平均数(SD ) 年龄是 28.8 (14.9 ) 年,与几乎相等的 male:female 比率。许多病人在表示是无征状的。呼吸急促和咳嗽是最普通的症状,并且疾病进行了进与英国管 pulmonale 联系的呼吸失败。大约三分之一个个案例开始被误诊并且对待同样肺的肺结核。额外肺的表明和 comorbidities 在我们的系列也是明显的。这系统的评论帮助决定肺的牙槽的 microlithiasis 的流行病学、临床的特征。进一步的研究被需要阐明 etiopathogenesis,诊断,和治疗学的选择,它在为肺的牙槽的 microlithiasis 开发并且识别 costeffective 治疗是有益的。 | Nidhya Ganesan Marie Moses Ambroise Anita Ramdas King Herald Kisku Kulwant Singh Renu G' Boy Varghese | 2015 | Frontiers of Medicine2015，9，2： | 2 |
| 4 | A double-blind, placebocontrolled trial of sertraline for depressive symptoms in patients with stable,chronic schizophrenis 显示文摘 | Mulholland C Lynch G King D J | 2003 | J Psychopharmacol2003，17，： | 1 |
| 5 | Heart rate variability in chronic traumatic brain injury显示文摘 | Lichtman SW Seliger G | 1997 | Brain Inj1997，11，6： | 1 |
| 6 | Correlation of heavy-truck driver fatigue with vehicle-based control measures显示文摘 | SIEGMUND G P KING D J MUMFORD D K | 1995 | SAE Paper 9525941995，，： | 1 |
| 7 | Assembly of foot-and- mouth disease virus empty capids synthesized by a vaccinia virus expression system显示文摘 | Abrams C C King A M Belsham G J | 1995 | J Gen Virol1995，76，： | 1 |
| 8 | The growth of geological structures by repeated earthquakes,1,Conceptual framework显示文摘 | king G C Stein R S Rundle J B | 1988 | Journal of Geophysical Research1988，93，13： | 1 |
| 9 | Restriction fragment length polymorphisms associated with water use efficiency in tomato显示文摘 | Martin B J Nienbuis J King G | 1989 | Science1989，243，： | 1 |
| 10 | Finance and growth:Schumpeter might be right显示文摘 | King R G Levine R | 1993 | The Quarterly Journal of Economics1993，108，3： | 1 |
| 11 | Flt3L and TK gene therapy eradicate multifocal glioma in a syngeneic glioblastoma model 显示文摘 | KING G D MUHAMMAD A K CURTIN J F | 2008 | Neuro Oncol2008，10，1： | 1 |
| 12 | Tributyltin in environmental samples from the Former Derecktor Shipyard, Coddington Cove, Newport RI显示文摘 | Wade T L Sweet S T Quinn J G Cairns R W King J W | 2004 | Environmental Pollution2004，129，2： | 1 |
| 13 | The role of protein kinase C activation andthe vascular complications of diabetes显示文摘 | Das Evcimen N King G L | 2007 | Pharmacol Res2007，55，6： | 1 |
| 14 | Antecedents of knowl- edge transfer from consultants to clients in enterprise sys- tem implementations 显示文摘 | KO D G KIRSH L J KING W R | 2005 | MIS Quarterly2005，29，1： | 1 |
| 15 | Aqueous phase reforming of glycerol for hydrogen production over Pt-Re supported on carbon显示文摘 | King D L Zhang L Xia G | | 0，，： | 1 |
| 16 | Self-organization in a multicore fiber laser array显示文摘 | E J Bochove P K Cheo G G King | 2003 | Opt Lett2003，28，14： | 1 |
| 17 | The Efficiencies of Cast Blasting in Wide Pits 显示文摘 | MARTIN R L KING M G | 1995 | Coal1995，，6： | 1 |
| 18 | Pulsed Laser Deposited ZnO for Device Application显示文摘 | Gardeniers J G E Boyd I W | 1996 | Appl Surf Sci1996，9698，： | 1 |
| 19 | An Investigation of the Structure Near the L2, 3 Edges of Argon, the M4, 5 Edges of Krypton and the N4, 5 Edges of Xenon, Using Electron Impact with High Resolution显示文摘 | Tronc M Read F H | 1977 | J Phys1977，10，： | 1 |
| 20 | The origin of large local uplift in extensional regions显示文摘 | King G C P Ellis S | 1990 | Nature1990，348，： | 1 |
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