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27篇 您的检索式:作者名="Kaback"
    题名 作者 年代 出处 被引量
1Characterization of Fam20C expression in odontogenesis and osteogenesis using transgenic mice显示文摘Our previous studies have demonstrated that Fam20 C promotes differentiation and mineralization of odontoblasts,ameloblasts,osteoblasts and osteocytes during tooth and bone development.Ablation of the Fam20 C gene inhibits bone and tooth growth by increasing fibroblast growth factor 23 in serum and causing hypophosphatemia in conditional knockout mice.However,control and regulation of the expression of Fam20 C are still unknown.In this study,we generated a transgenic reporter model which expresses green fluorescence protein(GFP) driven by the Fam20 C promoter.Recombineering was used to insert a 16 kb fragment of the mouse Fam20 C gene(containing the 15 kb promoter and 1.1 kb of exon 1) intoa pBluescript SK vector with the topaz variant of GFP and a bovine growth hormone polyadenylation sequence.GFP expression was subsequently evaluated by histomorphometry on cryosections from E14 to adult mice.Fluorescence was evident in the bone and teeth as early as E17.5.The GFP signal was maintained stably in odontoblasts and osteoblasts until 4 weeks after birth.The expression of GFP was significantly reduced in teeth,alveolar bone and muscle by 8 weeks of age.We also observed colocalization of the GFP signal with the Fam20 C antibody in postnatal 1- and 7-day-old animals.Successful generation of Fam20C-GFP transgenic mice will provide a unique model for studying Fam20 C gene expression and the biological function of this gene during odontogenesis and osteogenesis.Er-Xia Du Xiao-Fang Wang Wu-Chen Yang Deborah Kaback Siu-Pok Yee Chun-Lin Qin Anne George Jian-Jun Hao 2015International Journal of Oral Science2015,7,2:3
2Expression of hyaluroan synthase messenger ribonucleic acids and their induction by interleukin-1β, in human orbital fibroblasts:potential insight into the molecular pathogenesis of thyroid- associated ophthalmopathy显示文摘Kaback LA Smith TJ 1999J Clin Endocrinol Metab1999,84,11:1
3The Cys154--Giy muta tion in LacY causes constitutive opening of the hydrophilic periplasmic pathway 显示文摘Nie Y Sabetfard FE Kaback HR 2008J Mol Biol2008,379,4:1
4Ocular hypotensive efficacy of travoprost in patients unsuccessfully treated with latanoprost显示文摘Kaback M Geanon J Katz G 2004Curr Med Res Opin2004,20,:1
5Teriparatide (1-34 human PTH) regulation of osterix during fracture repair显示文摘Soung YD Naik A Kaback LA 2008J Cell Biochem2008,105,1:1
6MAL6 of Saccharomyces:a complex genetic locus containing three genes required for maltose fermentation显示文摘NEEDLEMAN R B KABACK D B DUBIN R A 1984Proceedings of the National Academy of Sciences of the United States of America1984,81,9:1
7Expression of hyaluronan synthase messenger ribonucleic acids and their induction by interleukin-1 beta in human orbital fibroblasts:potential insight into the molecular pathogenesis of thyroid-associated ophthalmopathy显示文摘Kaback LA Smith TJ 1999J Clin Endocrinol Metab1999,84,11:1
8The IFI/Plenum Chemical Indexing Systems显示文摘Kaback SM Computer Handling of Generic Chemical0,,:1
9Selective induction of tissue inhibitor of metalloproteinase-1 in bleomycin-induced pulmonary fibrosis显示文摘Mndtes DK Elston AL Kaback LA 2001Am J Respir Cell Mol Biol2001,24,5:1
10Osterix/Sp7 regulates mesenchymal stem cell mediated endochondral ossification显示文摘Kaback LA Soung do Y Naik A 2008J Cell Physiol2008,214,1:1
11Selective induction of tissue inhibitor of metalloproteinase-1 in bleomycin-induced pulmonary fibrosis显示文摘MADTES D K ELSTON A L KABACK L A 2001Am J Respir Cell Mol Biol2001,24,5:1
12Selective induction of tissue inhibitor of metalloproteinase 2 1inbleo mycin 2 induced pulmonary fibrosis显示文摘Madtes D K Elston A L Kaback L A 0,,:1
13Expression of hyaluronan synthase messenger ribonucleic acids and their induction by interleukin-1beta in human orbital fibroblasts: potential insight into the molecular pathogenesis of thyroid-associated ophthalmopathy显示文摘Kaback L Smith T 1999J Clin Endocrinol Metab1999,84,11:1
14Expression of hyaluronan synthase messenger ribonucleic acids and their induction by interleukin-1beta in human orbital fibroblasts: potential insight into the molecular pathogenesis of thyroid-associated ophthalmopathy显示文摘Kaback L A Smith T J 1999J Clin Endocrinol Metab1999,84,:1
15Teriparatide (1-34 human PTH) regulation of osterix during fracture repair 显示文摘Kaback L A Soung do Y Naik A 2008d Cell Biochem2008,,:1
16Teriparatide (1-34 human PTH) regulation of osterix during fracture repair显示文摘Kaback LA Soung do Y Naik A 0,,01:1
17Lactose permease as a paradigm for membrane transport proteins显示文摘ABRAMSON J IWATA S KABACK H R 2004Mol Membr Bioi2004,21,:1
18Teriparatide (1-34 human PTH) regulation of osterix during fracture repair显示文摘Kaback L A Soung-do Y Naik A 2008J Cell Biochem2008,105,1:1
19Teriparatide ( 1-34 human PTH) regulation of osterix during fracture repair 显示文摘Soung YD Naik A Kaback LA 2008J Cell Biochem2008,105,1:1
20Molecular biology and energetics of membrane transport显示文摘Kaback H R 1976 1976J Cell Physiol1976,89,:1
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