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| 1 | Patients with primary biliary cirrhosis have increased serum total antioxidant capacity measured with the crocin bleaching assay显示文摘AIM: The balance between oxidants and antioxidants can play an important role in the initiation and development of liver diseases. Recently, we have described a new automated method for the determination of total antioxidant capacity (TAC) in human serum and plasma.METHODS: We measured TAC and corrected TAC (CTAC -abstraction of interactions due to endogenous uric acid,bilirubin and albumin) in 52 patients with chronic liver diseases (41 patients with primary biliary cirrhosis (PBC),10 patients with chronic hepatitis C and 13 patients with viral HCV cirrhosis) as well as in 10 healthy controls. In 23 PBC patients measurement were also done 6 mo after treatment with ursodeoxycholic acid (UDCA). The TAC assay was based on a modification of the crocin bleaching assay. The results were correlated with routine laboratory measurements and the histological stage of PBC.RESULTS: There were no significant differences in TAC between the various groups. However, CTAC was considerably increased in the PBC group compared to controls and cirrhotics. Analysis of these patients according to disease stages showed that this increase was an early phenomenon observed only in stages Ⅰ and Ⅱ compared to controls, cirrhotics and patients with chronic hepatitis C).After 6 mo of treatment with UDCA, levels of CTAC decreased to those similar to that of controls.CONCLUSION: Patients in the early stages of PBC present with high levels of corrected total antioxidant capacity and this maybe related to the pathophysiology of the disease. UDCA treatment restores the levels of CTAC to control levels. | George Notas Niki Miliaraki Marilena Kampa Fillipos Dimoulios Erminia Matrella Adam Hatzidakis Elias Castanas Elias Kouroumalis | 2005 | World Journal of Gastroenterology2005，11，27： | 13 |
| 2 | Human health effects of air pollution显示文摘 | Marilena Kampa Elias Castanas | 2007 | Environmental Pollution2007，，2： | 2 |
| 3 | Human health effects of air pollution显示文摘 | KAMPA M CASTANAS E | 2008 | Environmental Pollution2008，151，2： | 1 |
| 4 | Current transport in amorphous silicon n/p junctions and their application as 'tunnel' junctions in tandem solar cells显示文摘 | Hegedus S S Kampas F Xi J | 1995 | Applied Physics Letters1995，67，： | 1 |
| 5 | Identification of a novel opioid peptide from human α sl casein显示文摘 | Kampa M Loukas S Hatzoglou A | 1996 | J Biochem1996，319，： | 1 |
| 6 | Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest,and NOS activation显示文摘 | Notas G Nifli A P Kampa M | 2006 | Biochim Biophys Acta2006，1760，11： | 1 |
| 7 | Polyphenols and cancer cell growth显示文摘 | Kampa M Nifli AP Notas G | 2007 | Rev Physiol Biochem Pharmacol2007，159，： | 1 |
| 8 | Human health effects of air pollution显示文摘 | Kampa M Castanas E | 2008 | Environmental Pollution2008，151，2： | 1 |
| 9 | Price induced irrigation water saving:Unraveling conflicts and synergies between European agricultural and water policies for a Greek water district显示文摘 | Kampas A Petsakos A Rozakis S | 2012 | Agricultural Systems2012，，113： | 1 |
| 10 | Mechanical sludge disintegration for the production of carbon source for biological nutrient removal 显示文摘 | Kampas P Parsons S A Pearce P | 2007 | Water Res2007，41，8： | 1 |
| 11 | Comparison be- tween disintegrated and fermented sewage sludge for pro- duction of a carbon source suitable for biological nutrient removal显示文摘 | Soares A Kampas P Maillard S | 2010 | J Hazard Mater2010，175，13： | 1 |
| 12 | Potent inhibitory action of red wine polyphenols on human breast cancer cells显示文摘 | DAMIANAKI A BAKOGEORGOU E KAMPA M | 2000 | J Cell Biochem2000，78，3： | 1 |
| 13 | An internal car- bon source for improving biological nutrient removal显示文摘 | Kampas P Parsons S A Pearce P | 2009 | Bioresour Technol2009，100，1： | 1 |
| 14 | Olea europaea leaf extract exerts L-type Ca 2+ channel antagonistic effects显示文摘 | A. Scheffler H.W. Rauwald B. Kampa U. Mann F.W. Mohr S. Dhein | 2008 | Journal of Ethnopharmacology2008，，2： | 1 |
| 15 | Administrative Costs and Instrument Choice for Stochastic Non-point Source Pollutants显示文摘 | Athanasios Kampas Ben White | 2004 | Environmental and Resource Economics2004，，2： | 1 |
| 16 | Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells,by inducing cell cycle arrest,and NOS activation显示文摘 | Notas G Nifli AP Kampa M | 2006 | Biochim Biophys Acta2006，1760，11： | 1 |
| 17 | Chemical Reactions in Plasma Deposition显示文摘 | Kampas F J | 1984 | Semiconductors and Semimetals1984，21，： | 1 |
| 18 | Imaging cellular network dynamics in three dimensions using fast 3D laser scanning显示文摘 | Werner Gobel Bjorn M Kampa Fritjof Helmchen | | 0，，01： | 1 |
| 19 | Opioid - somatostatin interactions in regulating cancer cell growth 显示文摘 | Hatzoglou A Kampa M Castanas E | 2005 | Front Biosci2005，，10： | 1 |
| 20 | Reactions of Hydrogen in the Deposition of Hydrogenated Amorphous Silicon by Glow Discharge and Reactive Sputtering显示文摘 | Kampas F J | 1982 | J Appl Phys1982，53，9： | 1 |
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