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| 1 | Preliminary study on modelling, fabrication by photo-chemical etching and in vivo testing of biodegradable magnesium AZ31 stents显示文摘Magnesium metal(Mg)is a promising material for stent applications due to its biocompatibility and ability to be resorbed by the body.Manufacturing of stents by laser cutting has become an industry standard.Our alternative approach uses photo-chemical etching to transfer a pattern of the stent onto a Mg sheet.In this study,we present three stages of creating and validating a stent prototype,which includes design and simulation using finite element analysis(FEA),followed by fabrication based on AZ31 alloy and,finally,in vivo testing in peripheral arteries of domestic pigs.Due to the preliminary character of this study,only six stents were implanted in two domestic farm pigs weighing 25-28 kg and they were evaluated after 28 days,with an interim follow-up on day 14.The left and right superficial femoral,the left iliac,and the right renal artery were selected for this study.The diameters of the stented artery segments were evaluated at the time of implantation,on day 14 and then,finally,on day 28,by quantitative vessel analysis(QVA)using fluoroscopic imaging.Optical Coherence Tomography(OCT)imaging displayed some malposition,breaks,stacking,and protrusion into the lumen at the proximal,distal,and mid-sections of the stented arteries.The stents degraded with time,but simultaneously became embedded in the intima.After 28 days,the animals were euthanized,and explanted vessels were fixed for micro-CT imaging and histology studies.Micro-CT imaging revealed stent morphological and volumetric changes due to the in-body degradation.An in vivo corrosion rate of 0.75 mm/year was obtained by the CT evaluation.The histology suggested no-life threatening effects,although moderate injury,inflammation,and endothelialization scores were observed. | Bala Subramanya Pavan Kumar Kandala Guangqi Zhang Capucine LCorriveau Mark Paquin Madeleine Chagnon Dana Begun Vesselin Shanov | 2021 | Bioactive Materials2021，6，6： | 2 |
| 2 | Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling Glucose regulatory protein 78 and AMPK显示文摘 | Kandala PK Srivastava SK | 2012 | Oncotarget2012，3，4： | 1 |
| 3 | Regulation of collagen degradation in the rat myocardium after infarction 显示文摘 | Cleutjens JPM Kandala JC Guarda E | 1995 | J Mol Cell Cardiol1995，27，： | 1 |
| 4 | Capacitive Sensors for Measuring Single-kernel Moisture Content in Corn显示文摘 | Kandala C V K Leffler R G Nelson S O | 1987 | American Society of Agricultural Engineers1987，30，3： | 1 |
| 5 | Classification of in-shell peanut kernels nondestructively using VIS/NIR reflectance spectroscopy显示文摘 | J. Sundaram C. V. K. Kandala C. L. Butts | 2010 | Sensing and Instrumentation for Food Quality and Safety2010，，2： | 1 |
| 6 | Clinical,laboratory,and pacing predictors of CRT response显示文摘 | Kandala J Altman RK Park MY | 2012 | J Cardiovasc Transl Res2012，5，： | 1 |
| 7 | Meta-analysis of short sleep duration and obesity in children and adults显示文摘 | Cappuccio FP Taggart FM Kandala NB | 2008 | Sleep2008，31，： | 1 |
| 8 | Gender-specific associations of short sleep duration with prevalent and incident hypertension:The Whitehall Ⅱ Study显示文摘 | Cappuccio FP Stranges S Kandala NB | 2007 | Hypertension2007，50，： | 1 |
| 9 | Clinical, laboratory, and pacing predictors of CRT response Of cardiovas显示文摘 | Kandala J Altman RK Park MY | 2012 | J Cardiovasc Trans Res2012，5，2： | 1 |
| 10 | Regulation of macroantophagy in ovari- an cancer cells in vitro and in vivo by controlling glucose regulatory protein 78 and AMPK显示文摘 | Kandala PK Srivastava SK | 2012 | Oncotarget2012，3，： | 1 |
| 11 | Geographic distribution of cardiovascular comorbidities in South Africa: a national cross-sectional analysis显示文摘 | Kandala N B Manda S O M Tigbe W W | 2014 | Journal of Applied Statistics2014，，6： | 1 |
| 12 | Regulation of collagen degradation in the rat myocardium after infarction 显示文摘 | Cleutjens J P M Kandala J C Guarda E | 1995 | J Mol Cell Cardiol1995，27，6： | 1 |
| 13 | Regulation of collagen degradation in the rat myocardium after infarction显示文摘 | Cleutjens JP Kandala JC Guarda E | 1995 | J Mol Cell Cardiol1995，27，6： | 1 |
| 14 | Moisture content determination for in-shell peanuts with a low-cost impedance analyzer and capacitor sensor 显示文摘 | Kandala C V K Butts C L Lamb M C | 2008 | T ASAE2008，51，： | 1 |
| 15 | Regulation of collagen degradation in the rat myocardium after infarction显示文摘 | Cleutjens JP Kandala JC Guarda E | 1995 | J Mol Cell Cardiol1995，27，6： | 1 |
| 16 | Interactions between GIPC–APPL and GIPC–TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes显示文摘 | Rajendra Kedlaya Gokul Kandala Tie Fu Liu Nityanand Maddodi Sulochana Devi Vijayasaradhi Setaluri | 2011 | Archives of Biochemistry and Biophysics2011，，2： | 1 |
| 17 | Measurement of moisture content in single kernels of peanuts:A nondestructive electrical method显示文摘 | KANDALA C V K NELSON S O | 1990 | Transactions of the ASAE1990，33，2： | 1 |
| 18 | Instrument for single-kernel nondestructive moisture measurement显示文摘 | KANDALA C V K NELSON S O LEFFLER R G | 1993 | Transactions of the ASAE1993，36，3： | 1 |
| 19 | Gender-specific associations of short sleep duration with prevalent and incident hypertension, the Whitehall Study 显示文摘 | Cappuccio FP Stranges S Kandala NB | 2007 | Hypertension2007，50，： | 1 |
| 20 | Nondestructive moisture determination in small samples of popcorn by RF impedance measurement显示文摘 | KANDALA C V K NELSON S O LAWRENCE K C | 1994 | Transactions of the ASAE1994，37，1： | 1 |
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