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| 1 | Oxidative stress in coronary artery disease: epigenetic perspective显示文摘 | Sana Venkata Vijaya Lakshmi Shaik Mohammad Naushad Cheruku Apoorva Reddy Kankanala Saumya Damera Seshagiri Rao Srigiridhar Kotamraju Vijay Kumar Kutala | 2013 | Molecular and Cellular Biochemistry2013，，1： | 2 |
| 2 | Roles for rice membrane dynamics and plasmodesmata during biotrophic invasion by the blast fungus 显示文摘 | KANKANALA P CZYMMEK K VAEENT B | 2007 | The Plant Cell2007，19，2： | 1 |
| 3 | Roles for rice membrane dynamics and plasmodesmata during biotrophic invasion by the blast fungus显示文摘 | Kankanala P Czymmek K Valent B | 2007 | The Plant Cell2007，19，2： | 1 |
| 4 | Role for rice membrane dynamics and plasmodesmata during biotrophic invasion by the blast fungus显示文摘 | Kankanala P Czymmek K Valent B | 2007 | The Plant Cell2007，19，： | 1 |
| 5 | A TFAA-H3PO4-mediated direct, metal-free and high-speed synthesis of aryl carboxylate esters from phenols显示文摘 | KANKANALA K REDDY VR MUKKANTI K | 2009 | Journal of Fluorine Chemistry2009，130，5： | 1 |
| 6 | Tribological behaviour of carbide-free bainific steel under dry wiling/sliding conditions显示文摘 | Leiro a Kankanala a Vuofinen E | 2011 | Wear2011，273，1： | 1 |
| 7 | Roles for rice membrane dynamics and plasmodeamata during biotrophic invasion by the blast fungus显示文摘 | Prasanna kankanala Kirk czymmek | 2007 | The plant cell2007，19，： | 1 |
| 8 | Roles for rice membrane dynamics and plasmodesmata during biotrophic invasion by the blast fungus显示文摘 | Kankanala P Czymmek K Valent B | 2007 | The Plant Ceil Online2007，19，2： | 1 |
| 9 | On finitely strained magnetorheological elastomers 显示文摘 | Kankanala S V Triantafyllidis N | 2004 | Journal of the Mechanics and Physics of Solids2004，52，： | 1 |
| 10 | Roles for rice membrane dynamics and plasmodesmata during biotrophic invasion by the blast fungus 显示文摘 | Kankanala P Czymmek K Valent B | 2007 | Plant Cell2007，19，： | 1 |
| 11 | Tribological BehaviourOf CarbideFfree Bainitic Steel Under Dry Rolling/Sliding Condi-tions 显示文摘 | Leiro A Kankanala A Vuorinen E | 2011 | Wear2011，273，： | 1 |
| 12 | Experimentsand modeling of iron-particle-filled magnetorheologicalelastomers 显示文摘 | Danas K Kankanala S V Triantafyllidis N | 2012 | Journal of the Mechanics and Physics ofSolids2012，60，： | 1 |
| 13 | Roles for ricemembrane dynam- ics and plasmodesmata duringbiotrophic invasion by the blast fungus 显示文摘 | Kankanala P Czymmek K Valent B | 2007 | Plant Cell2007，，19： | 1 |
| 14 | Discovery of N-benzyl hydroxypyridone carboxamides as a novel and potent antiviral chemotype against human cytomegalovirus (HCMV)显示文摘Current drugs for treating human cytomegalovirus(HCMV)infections are limited by resistance and treatment-associated toxicities.In developing mechanistically novel HCMV antivirals,we discovered an N-benzyl hydroxypyridone carboxamide antiviral hit(8a)inhibiting HCMV in submicromolar range.We describe herein the structure–activity relationship(SAR)for 8a,and the characterization of potent analogs for cytotoxicity/cytostatic property,the preliminary mechanism of action,and the absorption,distribution,metabolism and excretion(ADME)properties.The SAR revealed a few pharmacophore features conferring optimal antiviral profile,including the 5-OH,the N-1 benzyl,at least one–CH_(2)−in the linker,and a di-halogen substituted phenyl ring in the amide moiety.In the end,we identified numerous analogs with sub-micromolar antiviral potency and good selectivity index.The preliminary mechanism of action characterization used a pUL89-C biochemical endonuclease assay,a virus entry assay,a time-of-addition assay,and a compound withdrawal assay.ADME profiling measuring aqueous solubility,plasma and liver microsomal stability,and parallel artificial membrane permeability assay(PAMPA)permeability demonstrated largely favorable drug-like properties.Together,these studies validate the N-benzyl hydroxypyridone carboxamide as a viable chemotype for potent and mechanistically distinct antivirals against HCMV. | Sameera Senaweera Tiffany C.Edwards Jayakanth Kankanala Yan Wang Rajkumar Lalji Sahani Jiashu Xie Robert J.Geraghty Zhengqiang Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 0 |
| 15 | 红眼在基层医疗中的诊断和治疗显示文摘红限是基层医疗最常见的眼科问题之一。几乎眼睛任何部位(包括眼睑、泪腺)发炎或流泪障碍,均可能导致红眼。尽管知道转诊病人到眼科医生处是至关重要的,但是初级保健医生经常可以有效地管理红眼。 | HOLLY CRONAU RAMANA REDDY KANKANALA THOMAS MAUGER 周洁清(译) 孙允伟(译) 于明军(译) | 2010 | 中国实用乡村医生杂志2010，，7： | 0 |
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