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	题名	作者	年代	出处	被引量
1	Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?显示文摘Frequent activation of phosphatidylinositol-3 kinases(PI3K)/Akt/m TOR signaling pathway in gastric cancer(GC) is gaining immense popularity with identification of mutations and/or amplifications of PIK3 CA gene or loss of function of PTEN,a tumor suppressor protein,to name a few; both playing a crucial role in regulating this pathway. These aberrations result in dysregulation of this pathway eventually leading to gastric oncogenesis,hence,there is a need for targeted therapy for more effective anticancer treatment. Several inhibitors are currently in either preclinical or clinical stages for treatment of solid tumors like GC. With so many inhibitors under development,further studies on predictive biomarkers are needed to measure the specificity of any therapeutic intervention. Herein,we review the common dysregulation of PI3K/Akt/m TOR pathway in GC and the various types of single or dual pathway inhibitors under development that might have a superior role in GC treatment. We also summarize the recent developments in identification of predictive biomarkers and propose use of predictive biomarkers to facilitate more personalized cancer therapy with effective PI3K/Akt/m TOR pathway inhibition.	Shikha Satendra Singh Wei Ney Yap Frank Arfuso Shreya Kar Chao Wang Wanpei Cai Arunasalam M Dharmarajan Gautam Sethi Alan Prem Kumar	2015	World Journal of Gastroenterology2015，21，43：	36
2	Methylglyoxal increase in uremia with special reference to snakebite-mediated acute renal failure 显示文摘	Mukhopadhyay S Ghosh A Kar M	2008	Clin Chim Acta2008，391，12：	1
3	Two-phase anaerobic digestion of water hyacinth or urban garbage显示文摘	CHANAKYA H N BORGAON KARS RAJAN M G C	1992	Bioresource Technology1992，42，：	1
4	Thrombytopenic coagultpathy( Kasabach-Merritt phenomenon ) is asso('iated with Kaposifi~rm hemangioendolhelionla and not with common infantile hemangioma 显示文摘	Sm'kar M Mulliken JB Kozakewich HP	1997	Ptast R econstr Surg1997，100，6：	1
5	Disease-specific im- pairments in quality of life during long-term follow-up of pa- tients with different pituitary adenomas显示文摘	Klaauw AA Kars M Biermasz NR	2008	Clin Endocrinol2008，69，5：	1
6	Relativistically correct hole-boring and ion acceleration by circularly polarized laser pulses显示文摘	A P L Robinson P Gibbon M Zepf S Kar R G Evans C Bellei	2009	Plasma Physics and Controlled Fusion2009，，2：	1
7	Testing of MEMS capacitive accelerometer structure through electro-static actuation 显示文摘	KAR S K SWAMY K B M MUKHERJEE B	2013	Microsystem Tech- nologies2013，19，1：	1
8	Aerodynamic parameter estimation using adaptive unscented Kalman filter显示文摘	Majeed M Kar I N	2013	Aircraft Engi- neering and Aerospace Technology2013，85，4：	1
9	Percutaneous mitral repair with the Mitr- aClip system : safety and midterm durability in the initial EVEREST ( Endovas- cular Valve Edge-to-Edge REpair Study ) cohort 显示文摘	Feldman T Kar S Rinaldi M	2009	J Am Coll Cardiol2009，54，：	1
10	Minimum interference routing of bandwidth guaranteed tunnels with MPLS traffic engineering application 显示文摘	KAR K KODIALAM M LAKSHMANT V	2000	IEEE Journal on Selected Areas in Communications2000，18，12：	1
11	Thermoelastic interaction with energy dissipation in an infinitely extended thin platecontaining a circular hole显示文摘	Kar A Kanoria M	2006	Far East Journal of Applied Mathematics2006，24，2：	1
12	Oxidized high-density lipoprotein inhibits platelet activation and aggregation via scavenger receptor BI显示文摘	Valiyaveettil M Kar N Ashraf MZ	2008	Blood2008，111，4：	1
13	Kalman filtering with intermittent observations: weak convergence to a stationary distribution显示文摘	Kar S Sinopoli B Moura J M F	2012	IEEE Transactions on Automatic Control2012，57，2：	1
14	Rotatory vibration of sphere of higher order viscoelastic solid显示文摘	Sengupta P R De N Kar M	1994	Internat J Math Math Sci1994，17，4：	1
15	Thermoelastic interaction with energy dissipation in an unbounded body with aspherical hole显示文摘	Kar A Kanoria M	2007	International Journal of Solids and Structures2007，44，9：	1
16	A recombinant en- velope protein vaccine against West Nile virus 显示文摘	Ledizet M Kar K Foellmer H G	2005	Vac- cine2005，23，30：	1
17	QD-Leaming:a collaborative distributed strategy for multi-agent reinforcement learning through consensus plus innovations显示文摘	KAR S MOURA J M F POOR H V	2013	IEEE Transactions on Signal Processing2013，61，7：	1
18	Thermoelastic interaction with energy dissipation in a transversely isotropic thin cir-cular disc显示文摘	Kar A Kanoria M	2007	Europian Journal of Mechanics A/Solids2007，26，6：	1
19	Immu- nohistochemical localization of macrophage CD68+, HLA-DR+ , L1+ and CD44+ subsets in uterine endo- metrium during different phases of menstrual cycle 显示文摘	KAR M SENGUPTA J KUMAR S	2004	Indian J Physiol Pharrnacol2004，48，3：	1
20	Design of Model - Based Optimizing Control Scheme for anAir - Conditioning System 显示文摘	Kumar M Kar I N	2010	HVAC & R Research2010，16，5：	1

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