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| 1 | Current position of ALPPS in the surgical landscape of CRLM treatment proposals显示文摘The Authors summarize problems,criticisms but also advantages and indications regarding the recent surgical proposal of associating liver partition and portal vein ligation(PVL)for staged hepatectomy(ALPPS)for the surgical management of colorectal liver metastases.Looking at published data,the technique,when compared with other traditional and well established methods such as PVL/portal vein embolisation(PVE),seems to give real advantages in terms of volumetric gain of future liver remnant.However,major concerns are raised in the literature and some questions remain unanswered,preliminary experiences seem to be promising.The method has been adopted all over the world over the last 2 years,even if oncological long-term results remain unknown,and benefit for patients is questionable.No prospective studies comparing traditional methods(PVE,PVL or classical 2 staged hepatectomy)with ALPPS are available to date.Technical reinterpretations of the original method were also proposed in order to enhance feasability and increase safety of the technique.More data about morbidity and mortality are also expected.The real role of ALPPS is,to date,still to be established.Large clinical studies,even if,for ethical reasons,in well selected cohorts of patients,are expected to better define the indications for this new surgical strategy. | Marcello Donati Gregor A Stavrou Karl J Oldhafer | 2013 | World Journal of Gastroenterology2013，19，39： | 16 |
| 2 | Computed tomography and patient risk:Facts,perceptions and uncertainties显示文摘Since its introduction in the 1970s, computed tomography(CT) has revolutionized diagnostic decision-making. One of the major concerns associated with the widespread use of CT is the associated increased radiation exposure incurred by patients. The link between ionizing radiation and the subsequent development of neoplasia has been largely based on extrapolating data from studies of survivors of the atomic bombs dropped in Japan in 1945 and on assessments of the increased relative risk of neoplasia in those occupationally exposed to radiation within the nuclear industry. However, the association between exposure to low-dose radiation from diagnostic imaging examinations and oncogenesis remains unclear. With improved technology, significant advances have already been achieved with regards to radiation dose reduction. There are several dose optimization strategies available that may be readily employed including omitting unnecessary images at the ends of acquired series, minimizing the number of phases acquired, and the use of automated exposure control as opposed to fixed tube current techniques. In addition, new image reconstruction techniques that reduce radiation dose have been developed in recent years with promising results. These techniques use iterative reconstruction algorithms to attain diagnostic quality images with reduced image noise at lower radiation doses. | Stephen P Power Fiachra Moloney Maria Twomey Karl James Owen J O'Connor Michael M Maher | 2016 | World Journal of Radiology2016，8，12： | 7 |
| 3 | Laparoscopic step 1 ALPPS with microwave transection of theliver for Klatskin tumors:Is it worthwhile?显示文摘To the Editor:Associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)was introduced in 2007[1].This technique is now used worldwide and has a wide spectrum of indications.However,scientific debate and un-regulated surgical experimentation concerning the application of this technique led the surgeons to organize the first Consensus Meeting[2]to build a scientific consensus.One of the most controversial indications to ALPPS is its application for Klatskin tumors.The aim of this letter is to ana- | marcello donati francesco basile karl j oldhafer | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，3： | 4 |
| 4 | Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial显示文摘 | Roger Stupp Monika E Hegi Warren P Mason Martin J van den Bent Martin JB Taphoorn Robert C Janzer Samuel K Ludwin Anouk Allgeier Barbara Fisher Karl Belanger Peter Hau Alba A Brandes Johanna Gijtenbeek Christine Marosi Charles J Vecht Karima Mokhtari Piet | 2009 | Lancet Oncology2009，，5： | 4 |
| 5 | AN OVERVIEW OF CMIP5 AND THE EXPERIMENT DESIGN显示文摘 | Taylor Karl E Stouffer Ronald J Meehl Gerald A | 2012 | EN2012，，4： | 3 |
| 6 | A novel therapeutic hepatitis B vaccine induces cellular and humoral immune responses and breaks tolerance in hepatitis B virus (HBV) transgenic mice显示文摘 | Pascale Buchmann Claudia Dembek Larissa Kuklick Clemens J?ger Raindy Tedjokusumo Miriam John von Freyend Uta Drebber Zbigniew Janowicz Karl Melber Ulrike Protzer | 2013 | Vaccine2013，，8： | 3 |
| 7 | C-reactive protein and radiographic findings of lower respiratory tract infection in infants显示文摘AIM To evaluate the association between C-reactive protein(CRP) and radiological evidence of lower respiratory tract infection(LRTI) in infants.METHODS All patients aged less than 4 years who presented with suspected lower respiratory tract infection,who received a peri-presentation chest radiograph and CRP blood measurement over an 18-mo period were included in the study.Age,gender,source of referral,CRP,white cell count,neutrophil count along with the patients' symptoms and radiologist's report were recorded.RESULTS Three hundred and eleven patients met the inclusioncriteria.Abnormal chest radiographs were more common in patients with elevated CRP levels(P < 0.01).Radiologic signs of LRTI were identified in 73.7% of chest radiographs when a patient had a CRP level between 50-99 mg/L.CRP levels were a better predictor of positive chest radiograph findings for those aged greater than I year compared to those 1 year or less.CONCLUSION CRP may be used in patients with suspected LRTI diagnosis to select those who are likely to have positive findings on chest radiograph,thus reducing unnecessary chest radiographs. | Maria Twomey Hannah Fleming Fiachra Moloney Kevin P Murphy Lee Crush Siobhan B O’Neill Oisin Flanagan Karl James Conor Bogue Owen J O’Connor Michael M Maher | 2017 | World Journal of Radiology2017，9，4： | 2 |
| 8 | Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer显示文摘 | Anne Fl?rcken Joachim Kopp Antje van Lessen Kamran Movassaghi Anna Takvorian Korinna J?hrens Markus M?bs Constanze Sch?nemann Birgit Sawitzki Karl Egerer Bernd D?rken Antonio Pezzutto J?rg Westermann | 2013 | Human Vaccines & Immunotherapeutics2013，，： | 2 |
| 9 | The reliability of investment property fair value estimates显示文摘 | J Richard Dietrich Mary S Harris Karl A Muller | 2001 | Journal of Accounting and Economics2001，，2： | 2 |
| 10 | The fabrication of color-tunable organic light-emitting diode displays via solution processing显示文摘Electroluminescent devices based on organic semiconductors have attracted significant attention owing to their promising applications in flat-panel displays.The conventional display pixel consisting of side-by-side arrayed red,green and blue subpixels represents the mature technology but bears an intrinsic deficiency of a low pixel density.Constructing an individual color-tunable pixel that comprises vertically stacked subpixels is considered an advanced technology.Although color-tunable organic light-emitting diodes(OLEDs)have been fabricated using the vacuum deposition of small molecules,the solution processing of conjugated polymers would enable a much simpler and inexpensive manufacturing process.Here we present the all-solution processing of color-tunable OLEDs comprising two vertically stacked polymer emitters.A thin layer of highly conducting and transparent silver nanowires is introduced as the intermediate charge injection contact,which allows the emission spectrum and intensity of the tandem devices to be seamlessly manipulated.To demonstrate a viable application of this technology,a 4-by-4 pixelated matrix color-tunable display was fabricated. | Fei Guo Andre Karl Qi-Fan Xue Kai Cheong Tam Karen Forberich Christoph J Brabec | 2017 | Light(Science & Applications)2017，6，1： | 2 |
| 11 | Effects of sampling, preparation and defecation on metal concentration in selected invertebrates at urban sites显示文摘 | BETTINA Z KARL J W | 2003 | Chemosphere2003，52，： | 1 |
| 12 | Comparison of synthetic surfactants and biosurfactants in enhancing biodegradation of polycyclic aromatic hydrocarbons显示文摘 | RANDHIR S M KARL J R | 2003 | Envionmental Toxicology and Chemical2003，22，10： | 1 |
| 13 | Efflux of dietary flavonoid quercetin 4'-β-glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistanceassociated protein2显示文摘 | Richard A W Karl J R George E L | 2000 | J Pharm Exp Ther2000，294，3： | 1 |
| 14 | On deformation of near a circular underground cavity subjected to incident plane P waves显示文摘 | Lee V W Karl J | 1993 | European Journal of Earthquake Engineering1993，，1： | 1 |
| 15 | Pareto ant colonyoptimization:A metaheuristic approach to multiobjectiveportfolio selection 显示文摘 | Karl D Walter J Richard F | 2004 | Annals of Operations Research2004，131，1234： | 1 |
| 16 | Transgenic zebrafish using transposable elements显示文摘 | Karl J C Mark D U Kimberly J | 2011 | Methods Cell Biol2011，104，： | 1 |
| 17 | Development of a quantitative method for the analysis of tobacco-specific nitrosa- mines in mainstream cigarette smoke using isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry 显示文摘 | Karl A W Nancy H F Fossett J E | 2005 | Analytical Chemistry2005，77，： | 1 |
| 18 | Electronic Energy Spectrum and the Concept of Capacitance in Quantum Dots显示文摘 | Macucci M Karl Hess Iafrate G J | 1993 | Phys Rev1993，48，17： | 1 |
| 19 | Aspects of coal properties and constitution important for gasification 显示文摘 | Karl H Heek V and Mulen H J | 1985 | Fuel1985，64，10： | 1 |
| 20 | Molecular simulation of hydrogen adsorption in single-walled carbon nanotubes and idealized carbon slit pores显示文摘 | Qinyu Wang J Karl Johnson | 1999 | J Chem Phys1999，110，： | 1 |
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