| 1 | In vivo theranostics with near-infraredemitting carbon dots—highly efficient photothermal therapy based on passive targeting after intravenous administration显示文摘Carbon dots that exhibit near-infrared fluorescence(NIR CDs)are considered emerging nanomaterials for advanced biomedical applications with low toxicity and superior photostability and targeting compared to currently used photoluminescence agents.Despite progress in the synthesis of NIR CDs,there remains a key obstacle to using them as an in vivo theranostic agent.This work demonstrates that the newly developed sulfur and nitrogen codoped NIR CDs are highly efficient in photothermal therapy(PTT)in mouse models(conversion efficiency of 59%)and can be readily visualized by photoluminescence and photoacoustic imaging.The real theranostic potential of NIR CDs is enhanced by their unique biodistribution and targeting.Contrary to all other nanomaterials that have been tested in biomedicine,they are excreted through the body’s renal filtration system.Moreover,after intravenous injection,NIR CDs are accumulated in tumor tissue via passive targeting,without any active species such as antibodies.Due to their accumulation in tumor tissue without the need for intratumor injection,high photothermal conversion,excellent optical and photoacoustic imaging performance,and renal excretion,the developed CDs are suitable for transfer to clinical biomedical practice. | Xin Bao Ye Yuan Jingqin Chen Bohan Zhang Di Li Ding Zhou Pengtao Jing Guiying Xu Yingli Wang Kateřina Holá Dezhen Shen Changfeng Wu Liang Song Chengbo Liu Radek Zbořil Songnan Qu | 2018 | Light(Science & Applications)2018，7，1： | 13 |
| 3 | Visualization of Wormlike Micelle Fluid Flow in a Mixing Tank显示文摘In this study,particle image velocimetry was applied to investigate flow fields of wormlike micelle(WLM) fluids in a mixing tank equipped with a four-blade,down-pumping,pitched blade turbine. First,the rheology of WLM fluids was investigated,and the Carreau model was utilized to describe their apparent viscosity. Then,the effects of the rotation speeds and rheological properties on the flow fields were studied using different WLM fluids at different rotation speeds. The results revealed that with increasing Reynolds number,the discharge angle decreases and the carven size increases. Furthermore,elastic effects of WLM fluids lead to a more curved flow and a smaller carven. | Hongyuan Wei Jieliang Lu Chong Gu Kate Xu Boonho Ng Leping Dang | 2018 | Transactions of Tianjin University2018，24，4： | 0 |
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