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| 1 | Catheter ablation of atrial fibrillation in elderly population显示文摘Background Although elderly patients have been included in published series of catheter ablation for atrial fibrillation (AF), clinicalbenefit and safety remain still less defined in this population. A retrospective analysis of the results of catheter ablation for AF in a large volumecenter focused on comparison of elderly patients with the rest of the patient cohort was conducted in this study. Methods Consecutive patientswho underwent catheter ablation for AF between January 2001 and December 2016 were analysed. A total population of 3197 patients wasdichotomized by the age of 70 years (394 elderly vs. 2803 younger subjects). Patients were followed in terms of arrhythmia status and sur-vival for a median period of 18 vs. 21 and 35 vs. 57 months, respectively. Results Elderly patients were more frequently females (49% vs.29%, P 〈 0.0001), had a history of hypertension (79% vs. 57%, P 〈 0.0001), diabetes (16% vs. 11%, P 〈 0.01), stroke (9% vs. 6%, P 〈 0.01),coronary/peripheral artery disease (14% vs. 8%, P 〈 0.0001), and CHAzDS2-VASc score (3.1 ± 1.3 vs. 1.5 ± 1.2 s, P 〈 0.0001). Major com-plications were more frequent in elderly (5.3% vs. 3.2%, P = 0.03); however, this difference was driven by vascular complications (3.6% vs.1.9%, P = 0.04). There were comparable rates of cerebrovascular (0.3 vs. 0.3%) or nonvascular complications (1.8 vs. 1.2%). Good arrhyth-mia control was inferior in elderly patients as compared with the rest of the cohort, both without and with antiarrhythmic drugs: 44.2% vs.58.2% (P 〈 0.0001) and 78.2 vs. 83.2% (P 〈 0.01), respectively. Poor arrhythmia control was associated with relative risk of all-cause mor-tality of 2.7 (95% CI: 1.1-6.4) in elderly patients and 1.4 (95% CI: 0.9-2.0) in younger subjects. Conclusions Catheter ablation for AF inelderly patients is safe although somewhat less effective. Good arrhythmia control is associated with better survival, especially in elderly patients. | Josef Kautzner Petr Peichl Marek Sramko Robert Cihak Bashar Aldhoon Dan Wichterle | 2017 | Journal of Geriatric Cardiology2017，14，9： | 9 |
| 2 | Morphology of atrial myocardial extensions into human caval veins : a postmortem study in patients with and without atrial fibrillation显示文摘 | Kholova I Kautzner J | 2004 | Circulation2004，10，： | 1 |
| 3 | Electrical Reconnection After Pulmonary Vein Isolation Is Contingent on Contact Force During Initial Treatment: Results From the EFFICAS I Study显示文摘 | Petr Neuzil Vivek Y. Reddy Josef Kautzner Jan Petru Dan Wichterle Dipen Shah Hendrik Lambert Aude Yulzari Erik Wissner Karl-Heinz Kuck | 2013 | Circulation: Arrhythmia and Electrophysiology2013，，： | 1 |
| 4 | Influence ofdifferent atrovntrcular delays on cardiac output during cardiac resyn-chronization therapy显示文摘 | Riedlbaauchova L Kautzner J Fridl P | 2005 | PACE2005，28，： | 1 |
| 5 | Influence of different atrioventricular and interventricular delays on cardiac output during cardiac resynchronization therapy显示文摘 | Riedlbauchova L Kautzner J Frldl P | 2005 | Pacing Clin Electrophysiol2005，28，1： | 1 |
| 6 | The spectrum of inter-and intraventricular abnormalities in patients eligible for cardiac resynchronization显示文摘 | Peichl P Kautzner J Cihak R | 2004 | Pacing Clin Electrophysiol2004，27，8： | 1 |
| 7 | Catheter ablation of stable ventricular tachycardia before defibrillator implantation in patients with coronary heart disease (VTACH): a multicentre randomised controlled trial显示文摘 | Karl-Heinz Kuck Anselm Schaumann Lars Eckardt Stephan Willems Rodolfo Ventura Etienne Delacrétaz Heinz-Friedrich Pitschner Josef Kautzner Burghard Schumacher Peter S Hansen | 2010 | The Lancet2010，，9708： | 1 |
| 8 | Anatomic charateritics of extensions of atrial myocardium into the pulmonary veins in subjects with and without atrial fibrillation显示文摘 | Kholova I Kautzner J | 2003 | PACE2003，26，6： | 1 |
| 9 | Perform- ance of left ventricular versus biventricular pacing in chronic heart failure assessed by stress echocardio- graphy显示文摘 | Riedlbauchova L Fridl P Kautzner J | 2004 | Pacing Clin Electrophysiol2004，27，： | 1 |
| 10 | Morphology of Atrial Extensions Into Human Caval Veins显示文摘 | Kholova I Kautzner J | 2004 | Circulation2004，110，5： | 1 |
| 11 | Influence of different atrioventricular and interventricular delays on cardiac output during cardiac resynchronization therapy显示文摘 | RIEDLBAUCHOVAL KAUTZNER J FRIDL P | 2005 | PACE2005，，1： | 1 |
| 12 | Current treatment in cardiac amyloidosis 显示文摘 | Kholova I Kautzner J | 2006 | Curr Treat Options Cardiovasc Med2006，8，6： | 1 |
| 13 | QT interval dispersion and its cinical utility显示文摘 | Kautzner J Malik M | 1997 | Pacing Clin Electrophydiol1997，20，102： | 1 |
| 14 | Influence of different atrioventricular and interventricular delays on cardiac output during cardiac resynchronization therapy显示文摘 | Riedlbauchova L Kautzner J Fridl P | 2005 | Pacing Clin Electrophysiol12005，28，1： | 1 |
| 15 | The value of B-type natriuretic peptide and big endothel 1 for detection of severe pulmonary hypertension in heart transplant candidates显示文摘 | Kubanek M Malek I Kautzner J | 2005 | Eur J Heart Failure2005，7，7： | 1 |
| 16 | The relationship between contact force and clinical outcome during radiofrequency catheter ablation of atrial fibrillation in the TOCCATA study显示文摘 | Reddy VY Shah D Kautzner J | 2012 | Heart Rhythm2012，9，11： | 1 |
| 17 | Acquired left ventricular-right atrial and fight ventrieular communication due to infective endocarditis after aortic valve replacement显示文摘 | Kautzner J Miroslav J Kozakova M | 1990 | Am Heart J1990，120，5： | 1 |
| 18 | Short-and long-term reproducibility of QT,QTc and QT dispersion measurement in healthy subjects显示文摘 | Gang Y Camm AJ | 1994 | PACE1994，17，： | 1 |
| 19 | The value of B typenuretic peptide and big endothelinl for detection of severe pulmonary hypertension in heart transplant candidates显示文摘 | Kubanek M Malek I Kautzner J | 2005 | Eur J Heart Fail2005，7，7： | 1 |
| 20 | Arthroscopic tech- nique using crossed K-wires for avulsion fractures of in- tercondylar eminence in children 显示文摘 | Havlas V Kautzner J Tre T | 2011 | Acta Chir Orthop Traumatol Cech2011，78，4： | 1 |
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